Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1881275 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (C-Term), (AA 718-745) antibody
- Antibody type
- Polyclonal
- Antigen
- This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term,AA 718-745
- Antibody clone number
- RB40563
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping.
Park J, Oh Y, Yoo L, Jung MS, Song WJ, Lee SH, Seo H, Chung KC
The Journal of biological chemistry 2010 Oct 8;285(41):31895-906
The Journal of biological chemistry 2010 Oct 8;285(41):31895-906
DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping.
Kurabayashi N, Hirota T, Sakai M, Sanada K, Fukada Y
Molecular and cellular biology 2010 Apr;30(7):1757-68
Molecular and cellular biology 2010 Apr;30(7):1757-68
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Mouse Dyrk1a Antibody (C-term) (ABIN1881275) western blot analysis in NCI-H460 cell line lysates (35 μg/lane). This demonstrates the Mouse Dyrk1a antibody detected the Mouse Dyrk1a protein (arrow).