ABIN359711

antibody from antibodies-online

Targeting: DYRK1A DYRK, DYRK1, MNBH

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN359711

Provider

antibodies-online

Product name

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A) (N-Term) antibody

Antibody type

Polyclonal

Description

Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

Wissing J, Jänsch L, Nimtz M, Dieterich G, Hornberger R, Kéri G, Wehland J, Daub H
Molecular & cellular proteomics : MCP 2007 Mar;6(3):537-47

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Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Adayev T, Chen-Hwang MC, Murakami N, Lee E, Bolton DC, Hwang YW
Biochemistry 2007 Jun 26;46(25):7614-24

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Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis.

Chang HS, Lin CH, Yang CH, Yen MS, Lai CR, Chen YR, Liang YJ, Yu WC
International journal of cancer 2007 Jun 1;120(11):2377-85

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DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.

Alvarez M, Altafaj X, Aranda S, de la Luna S
Molecular biology of the cell 2007 Apr;18(4):1167-78

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB