ABIN393530
antibody from antibodies-online
Targeting: CDK5RAP3
C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393530 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) (AA 1-507) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-507
- Isotype
- IgG
- Antibody clone number
- 1G4
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling.
Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice.
Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation.
LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB.
Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma.
Wu J, Lei G, Mei M, Tang Y, Li H
The Journal of biological chemistry 2010 May 14;285(20):15126-36
The Journal of biological chemistry 2010 May 14;285(20):15126-36
Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice.
Zhuo ML, Huang Y, Chen JZ, Sun LH, Yang RF, Chen HZ, Lv X, Li HL, Wei YS, Liu G, Zhang R, Ma TM, Cai H, Hui RT, Liu DP, Liang CC
Cardiovascular research 2009 Nov 1;84(2):292-9
Cardiovascular research 2009 Nov 1;84(2):292-9
Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation.
Jiang H, Wu J, He C, Yang W, Li H
Cell research 2009 Apr;19(4):458-68
Cell research 2009 Apr;19(4):458-68
LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB.
Wang J, An H, Mayo MW, Baldwin AS, Yarbrough WG
Cancer cell 2007 Sep;12(3):239-51
Cancer cell 2007 Sep;12(3):239-51
Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma.
Stav D, Bar I, Sandbank J
The International journal of biological markers 2007 Apr-Jun;22(2):108-13
The International journal of biological markers 2007 Apr-Jun;22(2):108-13
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Supportive validation
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- Experimental details
- WB
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC