CABT-BL3560

antibody from Creative Diagnostics
Targeting: TG AITD3, TGN
Provider product page for CABT-BL3560
ELISA

Antibody data

Product number
CABT-BL3560 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-TG monoclonal antibody, clone 22B27
Antibody type
Monoclonal
Description
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
22B27
Storage
Store at 4&deg
TG protein structure - CABT-BL3560 shown in red.