CABT-BL3560

antibody from Creative Diagnostics

Targeting: TG AITD3, TGN

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL3560

Provider

Creative Diagnostics

Product name

Anti-TG monoclonal antibody, clone 22B27

Antibody type

Monoclonal

Description

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

22B27

Storage

Store at 4&deg