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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 12551-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12551-1-AP, RRID:AB_1080025
- Product name
- Factor XII antibody
- Antibody type
- Polyclonal
- Description
- Factor XII antibody (Cat. #12551-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inflammation contributes to trauma-induced coagulopathy by oxidation of multiple clotting factors.
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women.
Maternal PM(2.5) Exposure and Cardiac Developmental Abnormalities in Fetuses and Neonates: Progressive Activation of the Complement and Coagulation Cascade.
Identification and Validation of Novel Metastasis-Related Immune Gene Signature in Breast Cancer.
TRIM28 regulates the coagulation cascade inhibited by p72 of African swine fever virus.
Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.
FXII regulates the formation of deep vein thrombosis via the PI3K/AKT signaling pathway in mice.
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Han CY, St John AE, Kim JH, Wang X, Ringgold KM, Neidig LE, Berenson R, Stern SA, White NJ
Redox biology 2026 Feb;89:103956
Redox biology 2026 Feb;89:103956
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women.
Chang Q, Wang S, Mai Q, Zhou C
Journal of ovarian research 2025 Jun 4;18(1):121
Journal of ovarian research 2025 Jun 4;18(1):121
Maternal PM(2.5) Exposure and Cardiac Developmental Abnormalities in Fetuses and Neonates: Progressive Activation of the Complement and Coagulation Cascade.
Guo Y, Niu S, Zhang Y, Yan W, Ji S, Ma L, Li G, Sang N
Environmental science & technology 2025 Aug 12;59(31):16156-16167
Environmental science & technology 2025 Aug 12;59(31):16156-16167
Identification and Validation of Novel Metastasis-Related Immune Gene Signature in Breast Cancer.
Ma S, Hao R, Lu YW, Wang HP, Hu J, Qi YX
Breast cancer (Dove Medical Press) 2024;16:199-219
Breast cancer (Dove Medical Press) 2024;16:199-219
TRIM28 regulates the coagulation cascade inhibited by p72 of African swine fever virus.
Zhu X, Li F, Fan B, Zhao Y, Zhou J, Wang D, Liu R, Zhao D, Fan H, Li B
Veterinary research 2024 Nov 12;55(1):149
Veterinary research 2024 Nov 12;55(1):149
Clinical and Molecular Characterizations of Papillary Thyroid Cancer in Children and Young Adults: A Multicenter Retrospective Study.
Guo K, Qian K, Shi Y, Sun T, Chen L, Mei D, Dong K, Gu S, Liu J, Lv Z, Wang Z
Thyroid : official journal of the American Thyroid Association 2021 Nov;31(11):1693-1706
Thyroid : official journal of the American Thyroid Association 2021 Nov;31(11):1693-1706
FXII regulates the formation of deep vein thrombosis via the PI3K/AKT signaling pathway in mice.
Meng Y, Yin Q, Ma Q, Qin H, Zhang J, Zhang B, Pang H, Tian H
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG
Nature communications 2016 May 18;7:11626
Nature communications 2016 May 18;7:11626
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12551-1-AP(F12 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 12551-1-AP(F12 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Factor XII antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Factor XII. This antibody recognizes human,mouse,rat antigen. The Factor XII antibody has been validated for the following applications: ELISA, WB, IHC analysis.
