FNab00394

antibody from FineTest Biotech
Targeting: AGT SERPINA8
Provider product page for FNab00394
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab00394 - Provider product page
Provider
FineTest Biotech
Product name
Angiotensinogen antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
angiotensinogen(serpin peptidase in
hibitor, clade A, member 8)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
AGT protein structure - FNab00394 shown in red.