Antibody data
- Antibody Data
- Antigen structure
- References [125]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 15282-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15282-1-AP, RRID:AB_2121440
- Product name
- HSP60 antibody
- Antibody type
- Polyclonal
- Description
- HSP60 antibody (Cat. #15282-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Zinc-Mediated Endoplasmic Reticulum Stress and Metallothionein Alleviate Arsenic-Induced Cardiotoxicity in Cyprinus Carpio.
Transcription Factor TFAP2B Exerts Neuroprotective Effects Targeting BNIP3-Mediated Mitophagy in Ischemia/Reperfusion Injury.
Blocking of FGFR4 signaling by F30 inhibits hepatocellular carcinoma cell proliferation through HMOX1-dependent ferroptosis pathway.
Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS.
Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events.
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Mechanistic study of heat shock protein 60-mediated apoptosis in DF-1 cells.
A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
Data-Independent Acquisition Proteomics and N-Terminomics Methods Reveal Alterations in Mitochondrial Function and Metabolism in Ischemic-Reperfused Hearts.
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Loss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway.
Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS.
A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia.
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer.
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis.
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).
IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Neospora caninum Evades Immunity via Inducing Host Cell Mitophagy to Inhibit Production of Proinflammatory Cytokines in a ROS-Dependent Manner.
AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Mammary Fibrosis Tendency and Mitochondrial Adaptability in Dairy Cows with Mastitis.
Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C.
A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication.
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Mouse midbrain dopaminergic neurons survive loss of the PD-associated mitochondrial protein CHCHD2.
CircEIF3H-IGF2BP2-HuR scaffold complex promotes TNBC progression via stabilizing HSPD1/RBM8A/G3BP1 mRNA.
Host HSPD1 Translocation from Mitochondria to the Cytoplasm Induced by Streptococcus suis Serovar 2 Enolase Mediates Apoptosis and Loss of Blood-Brain Barrier Integrity.
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response.
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.
Role of caspase-8 and/or -9 as biomarkers that can distinguish the potential to cause toxic- and immune related-adverse event, for the progress of acetaminophen-induced liver injury.
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells.
Molecular cloning and characterization of HSP60 gene in domestic pigeons (Columba livia) and differential expression patterns under temperature stress.
Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
Streptococcus suis serotype 2 enolase interaction with host brain microvascular endothelial cells and RPSA-induced apoptosis lead to loss of BBB integrity.
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice.
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
ATF4 Mediates Mitochondrial Unfolded Protein Response in Alveolar Epithelial Cells.
ChREBP-β regulates thermogenesis in brown adipose tissue.
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma.
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia.
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function.
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity Reactions.
EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming.
First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa.
A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.
Impacts of simultaneous exposure to arsenic (III) and copper (II) on inflammatory response, immune homeostasis, and heat shock response in chicken thymus.
Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants.
Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken.
Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines.
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations.
Potential urine proteomics biomarkers for primary nephrotic syndrome.
Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network.
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins.
Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation.
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade.
Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
Alterations of mitochondrial protein assembly and jasmonic acid biosynthesis pathway in Honglian (HL)-type cytoplasmic male sterility rice.
Membrane proteomic analysis comparing squamous cell lung cancer tissue and tumour-adjacent normal tissue.
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.
Dong H, Song H, Liu Y, Zou H
Biological trace element research 2024 Sep;202(9):4203-4215
Biological trace element research 2024 Sep;202(9):4203-4215
Transcription Factor TFAP2B Exerts Neuroprotective Effects Targeting BNIP3-Mediated Mitophagy in Ischemia/Reperfusion Injury.
Peng Y, Jia J, Zhang M, Ma W, Cui Y, Yu M
Molecular neurobiology 2024 Oct;61(10):7319-7334
Molecular neurobiology 2024 Oct;61(10):7319-7334
Blocking of FGFR4 signaling by F30 inhibits hepatocellular carcinoma cell proliferation through HMOX1-dependent ferroptosis pathway.
Huang F, Shi X, Hu M, Yan H, Li X, Ding Y, Zheng X, Cai X, Dai S, Xia Q, Cai Y
European journal of pharmacology 2024 May 5;970:176493
European journal of pharmacology 2024 May 5;970:176493
Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS.
Oliveira NAS, Pinho BR, Pinto J, Guedes de Pinho P, Oliveira JMA
Free radical biology & medicine 2024 May 1;217:126-140
Free radical biology & medicine 2024 May 1;217:126-140
Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events.
Edington AR, Connor OM, Marlar-Pavey M, Friedman JR
bioRxiv : the preprint server for biology 2024 Mar 22;
bioRxiv : the preprint server for biology 2024 Mar 22;
The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy.
Xu WN, Zheng HL, Yang RZ, Sun YF, Peng BR, Liu C, Song J, Jiang SD, Zhu LX
Cell biology and toxicology 2024 Mar 13;40(1):16
Cell biology and toxicology 2024 Mar 13;40(1):16
Reactive metabolite of trovafloxacin activates inflammasomes: Implications for trovafloxacin-induced liver injury.
Tanaka S, Noda T, Urashima K, Ijiri Y, Kohda Y, Kato R
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Journal of applied toxicology : JAT 2024 Jun;44(6):846-852
Mechanistic study of heat shock protein 60-mediated apoptosis in DF-1 cells.
Li Y, Cao S, Li Y
Poultry science 2024 Jun;103(6):103619
Poultry science 2024 Jun;103(6):103619
A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Kumar A, Gok MO, Nguyen KN, Connor OM, Reese ML, Wideman JG, Muñoz-Gómez SA, Friedman JR
Current biology : CB 2024 Jun 17;34(12):2606-2622.e9
Current biology : CB 2024 Jun 17;34(12):2606-2622.e9
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
Lin N, Sun L, Chai J, Qi H, Zhao Y, Ma J, Xia M, Hu X
Cancer cell international 2024 Jan 18;24(1):38
Cancer cell international 2024 Jan 18;24(1):38
Data-Independent Acquisition Proteomics and N-Terminomics Methods Reveal Alterations in Mitochondrial Function and Metabolism in Ischemic-Reperfused Hearts.
Hartley B, Bassiouni W, Roczkowsky A, Fahlman R, Schulz R, Julien O
Journal of proteome research 2024 Feb 2;23(2):844-856
Journal of proteome research 2024 Feb 2;23(2):844-856
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.
Liu PY, Hong KF, Liu YD, Sun ZY, Zhao TT, Li XL, Lao CC, Tan SF, Zhang HY, Zhao YH, Xie Y, Xu YH
Chinese medicine 2024 Feb 16;19(1):27
Chinese medicine 2024 Feb 16;19(1):27
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
Zhan XZ, Luo P, Zhang C, Zhang LJ, Shen X, Jiang DL, Liu WJ
Animal reproduction science 2024 Aug;267:107540
Animal reproduction science 2024 Aug;267:107540
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma.
Cai Y, Chen X, Lu T, Fang X, Ding M, Yu Z, Hu S, Liu J, Zhou X, Wang X
International journal of biological sciences 2023;19(14):4627-4643
International journal of biological sciences 2023;19(14):4627-4643
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Shelton SD, House S, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P
bioRxiv : the preprint server for biology 2023 Sep 5;
bioRxiv : the preprint server for biology 2023 Sep 5;
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Almeida LM, Oliveira Â, Oliveira JMA, Pinho BR
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Sang Y, Yang Q, Guo Y, Liu X, Shen D, Jiang C, Wang X, Li K, Wang H, Yang C, Ding L, Sun H, Guo X, Li C
The Journal of biological chemistry 2023 Oct;299(10):105183
The Journal of biological chemistry 2023 Oct;299(10):105183
Loss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway.
Chen T, Li D, Wang Y, Shen X, Dong A, Dong C, Duan K, Ren J, Li W, Shu G, Yang J, Xie Y, Qian F, Zhou J
British journal of cancer 2023 Oct;129(8):1261-1273
British journal of cancer 2023 Oct;129(8):1261-1273
Chronic stress hinders sensory axon regeneration via impairing mitochondrial cristae and OXPHOS.
Ruan Y, Cheng J, Dai J, Ma Z, Luo S, Yan R, Wang L, Zhou J, Yu B, Tong X, Shen H, Zhou L, Yuan TF, Han Q
Science advances 2023 Oct 6;9(40):eadh0183
Science advances 2023 Oct 6;9(40):eadh0183
A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Kumar A, Gok MO, Nguyen KN, Reese ML, Wideman JG, Muñoz-Gómez SA, Friedman JR
bioRxiv : the preprint server for biology 2023 Oct 4;
bioRxiv : the preprint server for biology 2023 Oct 4;
Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia.
Henning Y, Willbrand K, Larafa S, Weißenberg G, Matschke V, Theiss C, Görtz GE, Matschke J
Cell death discovery 2023 Oct 25;9(1):398
Cell death discovery 2023 Oct 25;9(1):398
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
Li D, Ding L, Yan Y, Xing Y, Xu J, Qin L
International journal of molecular sciences 2023 Nov 28;24(23)
International journal of molecular sciences 2023 Nov 28;24(23)
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection.
Li Y, Cao H, Qiu D, Wang N, Wang Y, Wen T, Wang J, Zhu H
Cancer cell international 2023 Nov 16;23(1):272
Cancer cell international 2023 Nov 16;23(1):272
PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer.
Ye H, Shi W, Yang J, Wang L, Jiang X, Zhao H, Qin L, Qin J, Li L, Cai W, Guan J, Yang H, Zhou H, Yu Z, Sun H, Jiao Z
Cancer research 2023 Nov 15;83(22):3767-3782
Cancer research 2023 Nov 15;83(22):3767-3782
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
Xu D, Hu G, Luo J, Cheng J, Wu D, Cheng L, Huang X, Fu S, Liu J
Veterinary microbiology 2023 May;280:109697
Veterinary microbiology 2023 May;280:109697
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, Zhao M, Shao Y, Li Z, Chen J, Chen S, Wang L
Cell death & disease 2023 May 13;14(5):325
Cell death & disease 2023 May 13;14(5):325
Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission.
Liao KM, Chen CJ, Luo WJ, Hsu CW, Yu SL, Yang PC, Su KY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114616
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114616
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Wu J, Deng F, Tang X, Chen W, Zhou R, Zhao T, Mao X, Shu F
Journal of hazardous materials 2023 Jun 15;452:131234
Journal of hazardous materials 2023 Jun 15;452:131234
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Liu Y, Liu K, Thorne RF, Shi R, Zhang Q, Wu M, Liu L
Cell reports 2023 Feb 28;42(2):112041
Cell reports 2023 Feb 28;42(2):112041
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103
Theriogenology 2023 Dec;212:91-103
Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes.
Kato R, Yamada T, Noda T, Tanaka S, Kohda Y, Ijiri Y
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
Toxicology in vitro : an international journal published in association with BIBRA 2023 Aug;90:105606
RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis.
Liu C, Wang L, Li Y, Guo M, Hu J, Wang T, Li M, Yang Z, Lin R, Xu W, Chen Y, Luo M, Gao F, Chen JY, Sun Q, Liu H, Sun B, Li W
Nucleic acids research 2023 Aug 11;51(14):7357-7375
Nucleic acids research 2023 Aug 11;51(14):7357-7375
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).
Duan Y, Yu J, Chen M, Lu Q, Ning F, Gan X, Liu H, Ye Y, Lu S, Lash GE
Journal of ovarian research 2023 Apr 22;16(1):81
Journal of ovarian research 2023 Apr 22;16(1):81
IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING.
Zeng X, Li X, Zhang Y, Cao C, Zhou Q
Journal of immunology research 2022;2022:3815853
Journal of immunology research 2022;2022:3815853
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
Neospora caninum Evades Immunity via Inducing Host Cell Mitophagy to Inhibit Production of Proinflammatory Cytokines in a ROS-Dependent Manner.
Zhang X, Wang Y, Gong P, Wang X, Zhang N, Chen M, Wei R, Zhang X, Li X, Li J
Frontiers in immunology 2022;13:827004
Frontiers in immunology 2022;13:827004
AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages.
Xia L, Zhang C, Lv N, Liang Z, Ma T, Cheng H, Xia Y, Shi L
Theranostics 2022;12(6):2928-2947
Theranostics 2022;12(6):2928-2947
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.
Pachnis P, Wu Z, Faubert B, Tasdogan A, Gu W, Shelton S, Solmonson A, Rao AD, Kaushik AK, Rogers TJ, Ubellacker JM, LaVigne CA, Yang C, Ko B, Ramesh V, Sudderth J, Zacharias LG, Martin-Sandoval MS, Do D, Mathews TP, Zhao Z, Mishra P, Morrison SJ, DeBerardinis RJ
Science advances 2022 Sep 2;8(35):eabn9550
Science advances 2022 Sep 2;8(35):eabn9550
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC
Nature metabolism 2022 Oct;4(10):1369-1401
Nature metabolism 2022 Oct;4(10):1369-1401
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Wang X, Duan C, Li Y, Lu H, Guo K, Ge X, Chen T, Shang Y, Liu H, Zhang D
International immunopharmacology 2022 Oct;111:109083
International immunopharmacology 2022 Oct;111:109083
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Mammary Fibrosis Tendency and Mitochondrial Adaptability in Dairy Cows with Mastitis.
Kan X, Hu G, Liu Y, Xu P, Huang Y, Cai X, Guo W, Fu S, Liu J
Metabolites 2022 Oct 28;12(11)
Metabolites 2022 Oct 28;12(11)
Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C.
Tang J, Abdullah SW, Li P, Wu J, Pei C, Mu S, Wang Y, Sun S, Guo H
mBio 2022 Oct 26;13(5):e0143422
mBio 2022 Oct 26;13(5):e0143422
A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication.
Shackleford G, Marziali LN, Sasaki Y, Claessens A, Ferri C, Weinstock NI, Rossor AM, Silvestri NJ, Wilson ER, Hurley E, Kidd GJ, Manohar S, Ding D, Salvi RJ, Feltri ML, D'Antonio M, Wrabetz L
PLoS genetics 2022 Nov;18(11):e1010477
PLoS genetics 2022 Nov;18(11):e1010477
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Lan B, Zhao H, He Y, Zhao Z, Wang N, Gao Y
Experimental cell research 2022 Nov 15;420(2):113358
Experimental cell research 2022 Nov 15;420(2):113358
Mouse midbrain dopaminergic neurons survive loss of the PD-associated mitochondrial protein CHCHD2.
Nguyen MK, McAvoy K, Liao SC, Doric Z, Lo I, Li H, Manfredi G, Nakamura K
Human molecular genetics 2022 May 4;31(9):1500-1518
Human molecular genetics 2022 May 4;31(9):1500-1518
CircEIF3H-IGF2BP2-HuR scaffold complex promotes TNBC progression via stabilizing HSPD1/RBM8A/G3BP1 mRNA.
Song X, Chen B, Liang Y, Li Y, Zhang H, Han D, Wang Y, Ye F, Wang L, Zhao W, Yang Q
Cell death discovery 2022 May 14;8(1):261
Cell death discovery 2022 May 14;8(1):261
Host HSPD1 Translocation from Mitochondria to the Cytoplasm Induced by Streptococcus suis Serovar 2 Enolase Mediates Apoptosis and Loss of Blood-Brain Barrier Integrity.
Wu T, Jia L, Lei S, Jiang H, Liu J, Li N, Langford PR, Liu H, Lei L
Cells 2022 Jun 29;11(13)
Cells 2022 Jun 29;11(13)
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Peng MZ, Shao YX, Li XZ, Zhang KD, Cai YN, Lin YT, Jiang MY, Liu ZC, Su XY, Zhang W, Jiang XL, Liu L
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response.
Hou M, Bao W, Gao Y, Chen J, Song G
Chemico-biological interactions 2022 Jan 5;351:109741
Chemico-biological interactions 2022 Jan 5;351:109741
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG.
Perivolidi VI, Violitzi F, Ioannidou E, Rinotas V, Stamatakis G, Samiotaki M, Panayotou G, Douni E
Journal of proteome research 2022 Feb 4;21(2):375-394
Journal of proteome research 2022 Feb 4;21(2):375-394
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, Han Q, He H, Zhou Q
Cell death & disease 2022 Feb 16;13(2):156
Cell death & disease 2022 Feb 16;13(2):156
Regorafenib and reactive metabolite of sunitinib activate inflammasomes: Implications for multi tyrosine kinase inhibitor-Iiduced immune related adverse events.
Kato R, Ijiri Y
Die Pharmazie 2022 Feb 1;77(2):54-58
Die Pharmazie 2022 Feb 1;77(2):54-58
Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.
Suzuki C, Fujiwara T, Shima H, Ono K, Saito K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Igarashi K, Harigae H
Molecular and cellular biology 2022 Dec 15;42(12):e0014322
Molecular and cellular biology 2022 Dec 15;42(12):e0014322
Role of caspase-8 and/or -9 as biomarkers that can distinguish the potential to cause toxic- and immune related-adverse event, for the progress of acetaminophen-induced liver injury.
Noda T, Kato R, Hattori T, Furukawa Y, Ijiri Y, Tanaka K
Life sciences 2022 Apr 1;294:120351
Life sciences 2022 Apr 1;294:120351
SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth.
Jiang M, Kuang Z, He Y, Cao Y, Yu T, Cheng J, Liu W, Wang W
Frontiers in endocrinology 2021;12:624309
Frontiers in endocrinology 2021;12:624309
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
Wang N, Zhu P, Huang R, Sun L, Dong D, Gao Y
Experimental and therapeutic medicine 2021 Nov;22(5):1246
Experimental and therapeutic medicine 2021 Nov;22(5):1246
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Wang D, Yin Y, Wang S, Zhao T, Gong F, Zhao Y, Wang B, Huang Y, Cheng Z, Zhu G, Wang Z, Wang Y, Ren J, Liang G, Li X, Huang Z
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells.
Della-Flora Nunes G, Wilson ER, Marziali LN, Hurley E, Silvestri N, He B, O'Malley BW, Beirowski B, Poitelon Y, Wrabetz L, Feltri ML
Nature communications 2021 Jun 2;12(1):3285
Nature communications 2021 Jun 2;12(1):3285
Molecular cloning and characterization of HSP60 gene in domestic pigeons (Columba livia) and differential expression patterns under temperature stress.
Yang J, Gu J, Hu Y, Wang N, Gao J, Wang P
Cell stress & chaperones 2021 Jan;26(1):115-127
Cell stress & chaperones 2021 Jan;26(1):115-127
Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity.
Shields LY, Li H, Nguyen K, Kim H, Doric Z, Garcia JH, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K
The Journal of biological chemistry 2021 Jan-Jun;296:100469
The Journal of biological chemistry 2021 Jan-Jun;296:100469
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q
Nature communications 2021 Jan 20;12(1):476
Nature communications 2021 Jan 20;12(1):476
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
Arzuk E, Karakuş F, Orhan H
Toxicology 2021 Jan 15;447:152628
Toxicology 2021 Jan 15;447:152628
Streptococcus suis serotype 2 enolase interaction with host brain microvascular endothelial cells and RPSA-induced apoptosis lead to loss of BBB integrity.
Liu H, Lei S, Jia L, Xia X, Sun Y, Jiang H, Zhu R, Li S, Qu G, Gu J, Sun C, Feng X, Han W, Langford PR, Lei L
Veterinary research 2021 Feb 22;52(1):30
Veterinary research 2021 Feb 22;52(1):30
ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
Hu M, Zhou M, Bao X, Pan D, Jiao M, Liu X, Li F, Li CY
The Journal of clinical investigation 2021 Feb 1;131(3)
The Journal of clinical investigation 2021 Feb 1;131(3)
N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
Scott GK, Mahoney S, Scott M, Loureiro A, Lopez-Ramirez A, Tanner JJ, Ellerby LM, Benz CC
Amino acids 2021 Dec;53(12):1927-1939
Amino acids 2021 Dec;53(12):1927-1939
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin.
Chen H, Zhang DM, Zhang ZP, Li MZ, Wu HF
Genes & genomics 2021 Dec;43(12):1433-1444
Genes & genomics 2021 Dec;43(12):1433-1444
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice.
Li D, Hu Z, He Q, Guo Y, Chong Y, Xu J, Qin L
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14856-14867
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14856-14867
Amiodarone, Unlike Dronedarone, Activates Inflammasomes via Its Reactive Metabolites: Implications for Amiodarone Adverse Reactions.
Kato R, Ijiri Y, Hayashi T
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
Chemical research in toxicology 2021 Aug 16;34(8):1860-1865
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction.
Kato R, Ijiri Y, Hayashi T, Uetrecht J
The Journal of toxicological sciences 2020;45(11):673-680
The Journal of toxicological sciences 2020;45(11):673-680
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
Mitochondrial DNA Haplogroup M7 Confers Disability in a Chinese Aging Population.
Sun D, Yao S, Wu F, Deng W, Ma Y, Jin L, Wang J, Wang X
Frontiers in genetics 2020;11:577795
Frontiers in genetics 2020;11:577795
ATF4 Mediates Mitochondrial Unfolded Protein Response in Alveolar Epithelial Cells.
Jiang D, Cui H, Xie N, Banerjee S, Liu RM, Dai H, Thannickal VJ, Liu G
American journal of respiratory cell and molecular biology 2020 Oct;63(4):478-489
American journal of respiratory cell and molecular biology 2020 Oct;63(4):478-489
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum.
Yang X, Zhao H, Wang Y, Liu J, Guo M, Fei D, Mu M, Xing M
Biological trace element research 2020 Jun;195(2):613-623
Biological trace element research 2020 Jun;195(2):613-623
Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.
Zhang ZL, Wang NN, Ma QL, Chen Y, Yao L, Zhang L, Li QS, Shi MH, Wang HF, Ying Z
Acta pharmacologica Sinica 2020 Jan;41(1):93-100
Acta pharmacologica Sinica 2020 Jan;41(1):93-100
Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp.
Wang Y, Zhao H, Nie X, Guo M, Jiang G, Xing M
Environmental research 2020 Dec;191:110063
Environmental research 2020 Dec;191:110063
MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma.
Yang L, Kong D, He M, Gong J, Nie Y, Tai S, Teng CB
Biochimica et biophysica acta. Molecular cell research 2020 Dec;1867(12):118826
Biochimica et biophysica acta. Molecular cell research 2020 Dec;1867(12):118826
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, Wang J, Sun L
IUBMB life 2020 Aug;72(8):1659-1679
IUBMB life 2020 Aug;72(8):1659-1679
Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia.
Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Apr 8;40(15):3119-3129
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Apr 8;40(15):3119-3129
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Shen Y, Ding M, Xie Z, Liu X, Yang H, Jin S, Xu S, Zhu Z, Wang Y, Wang D, Xu L, Zhou X, Wang P, Bi J
Frontiers in cellular neuroscience 2019;13:568
Frontiers in cellular neuroscience 2019;13:568
Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function.
Guan M, Zhang Y, Huang Q, He L, Fang Q, Zhang J, Gao S, Fang J, Ma Y, Su K, Gao X
American journal of translational research 2019;11(3):1343-1358
American journal of translational research 2019;11(3):1343-1358
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
Wang W, Wang M, Ruan Y, Tan J, Wang H, Yang T, Li J, Zhou Q
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
The 2-Hydroxyiminostilbene Metabolite of Carbamazepine or the Supernatant from Incubation of Hepatocytes with Carbamazepine Activates Inflammasomes: Implications for Carbamazepine-Induced Hypersensitivity Reactions.
Kato R, Ijiri Y, Hayashi T, Uetrecht J
Drug metabolism and disposition: the biological fate of chemicals 2019 Oct;47(10):1093-1096
Drug metabolism and disposition: the biological fate of chemicals 2019 Oct;47(10):1093-1096
EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming.
Meng F, Wu L, Dong L, Mitchell AV, James Block C, Liu J, Zhang H, Lu Q, Song WM, Zhang B, Chen W, Hu J, Wang J, Yang Q, Hüttemann M, Wu G
Nature communications 2019 Nov 6;10(1):5033
Nature communications 2019 Nov 6;10(1):5033
First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa.
Santiago J, Silva JV, Fardilha M
International journal of molecular sciences 2019 Nov 5;20(21)
International journal of molecular sciences 2019 Nov 5;20(21)
A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
Chen D, Liu X, Xia T, Tekcham DS, Wang W, Chen H, Li T, Lu C, Ning Z, Liu X, Liu J, Qi H, He H, Piao HL
iScience 2019 Jun 28;16:177-191
iScience 2019 Jun 28;16:177-191
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D
EBioMedicine 2019 Jan;39:239-254
EBioMedicine 2019 Jan;39:239-254
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
Xu H, Li Y, Liu R, Wu L, Zhang C, Ding N, Ma A, Zhang J, Xie X
Neuropeptides 2019 Aug;76:101936
Neuropeptides 2019 Aug;76:101936
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.
Flippo KH, Gnanasekaran A, Perkins GA, Ajmal A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Sep 19;38(38):8233-8242
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Sep 19;38(38):8233-8242
Impacts of simultaneous exposure to arsenic (III) and copper (II) on inflammatory response, immune homeostasis, and heat shock response in chicken thymus.
Liu J, Zhao H, Wang Y, Shao Y, Zhang L, Xing M
International immunopharmacology 2018 Nov;64:60-68
International immunopharmacology 2018 Nov;64:60-68
Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants.
Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM
JCI insight 2018 Nov 2;3(21)
JCI insight 2018 Nov 2;3(21)
Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken.
Shao Y, Zhao H, Wang Y, Liu J, Li J, Chai H, Xing M
Environmental science and pollution research international 2018 Mar;25(8):7719-7729
Environmental science and pollution research international 2018 Mar;25(8):7719-7729
Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines.
Wang Y, Zhao H, Liu J, Shao Y, Li J, Luo L, Xing M
International immunopharmacology 2018 Jul;60:64-75
International immunopharmacology 2018 Jul;60:64-75
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773
Cancer science 2018 Dec;109(12):3762-3773
Three human aminoacyl-tRNA synthetases have distinct sub-mitochondrial localizations that are unaffected by disease-associated mutations.
González-Serrano LE, Karim L, Pierre F, Schwenzer H, Rötig A, Munnich A, Sissler M
The Journal of biological chemistry 2018 Aug 31;293(35):13604-13615
The Journal of biological chemistry 2018 Aug 31;293(35):13604-13615
Potential urine proteomics biomarkers for primary nephrotic syndrome.
Choi YW, Kim YG, Song MY, Moon JY, Jeong KH, Lee TW, Ihm CG, Park KS, Lee SH
Clinical proteomics 2017;14:18
Clinical proteomics 2017;14:18
Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network.
Liu X, Wang W, Song G, Wei X, Zeng Y, Han P, Wang D, Shao M, Wu J, Sun H, Xiong G, Li S
PloS one 2017;12(8):e0182558
PloS one 2017;12(8):e0182558
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Wu L, Guo X, Lyu Y, Clarke SL, Lucas EA, Smith BJ, Hildebrand D, Wang W, Medeiros DM, Shen X, Lin D
Scientific reports 2017 Nov 7;7(1):14624
Scientific reports 2017 Nov 7;7(1):14624
Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken.
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M
Oncotarget 2017 Nov 17;8(58):98103-98116
Oncotarget 2017 Nov 17;8(58):98103-98116
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Chang CH, Liu WT, Hung HC, Gean CY, Tsai HM, Su CL, Gean PW
BMC cancer 2017 Dec 29;17(1):905
BMC cancer 2017 Dec 29;17(1):905
Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins.
Shi M, Liu Y, Feng L, Cui Y, Chen Y, Wang P, Wu W, Chen C, Liu X, Yang W
Evidence-based complementary and alternative medicine : eCAM 2015;2015:278014
Evidence-based complementary and alternative medicine : eCAM 2015;2015:278014
Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation.
Zhao Y, Zhang C, Wei X, Li P, Cui Y, Qin Y, Wei X, Jin M, Kohama K, Gao Y
Scientific reports 2015 Oct 19;5:15352
Scientific reports 2015 Oct 19;5:15352
Identification of Hsf1 as a novel androgen receptor-regulated gene in mouse Sertoli cells.
Yang L, Wang Y, Zhang Q, Lai Y, Li C, Zhang Q, Huang W, Duan Y, Jiang Z, Li X, Cai Z, Mou L, Gui Y
Molecular reproduction and development 2014 Jun;81(6):514-23
Molecular reproduction and development 2014 Jun;81(6):514-23
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD
Cell 2014 Jul 31;158(3):607-19
Cell 2014 Jul 31;158(3):607-19
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu C, Lin JJ, Yang ZY, Tsai CC, Hsu JL, Wu YJ
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade.
Li HH, Su JH, Chiu CC, Lin JJ, Yang ZY, Hwang WI, Chen YK, Lo YH, Wu YJ
Marine drugs 2013 Jul 22;11(7):2625-42
Marine drugs 2013 Jul 22;11(7):2625-42
Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.
Cheng KC, Huang HH, Hung CT, Chen CC, Wu WC, Suen JL, Chen KJ, Wu YJ, Chang CH
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2013 Dec;251(12):2777-87
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2013 Dec;251(12):2777-87
A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.
Yang MS, Wang HS, Wang BS, Li WH, Pang ZF, Zou BK, Zhang X, Shi XT, Mu DB, Zhang DX, Gao YS, Sun XW, Xia SJ
Diagnostic pathology 2013 Apr 15;8:58
Diagnostic pathology 2013 Apr 15;8:58
Alterations of mitochondrial protein assembly and jasmonic acid biosynthesis pathway in Honglian (HL)-type cytoplasmic male sterility rice.
Liu G, Tian H, Huang YQ, Hu J, Ji YX, Li SQ, Feng YQ, Guo L, Zhu YG
The Journal of biological chemistry 2012 Nov 16;287(47):40051-60
The Journal of biological chemistry 2012 Nov 16;287(47):40051-60
Membrane proteomic analysis comparing squamous cell lung cancer tissue and tumour-adjacent normal tissue.
Li B, Chang J, Chu Y, Kang H, Yang J, Jiang J, Ma H
Cancer letters 2012 Jun 1;319(1):118-24
Cancer letters 2012 Jun 1;319(1):118-24
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Su TR, Lin JJ, Chiu CC, Chen JY, Su JH, Cheng ZJ, Hwang WI, Huang HH, Wu YJ
Electrophoresis 2012 Apr;33(7):1139-52
Electrophoresis 2012 Apr;33(7):1139-52
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells.
Liu CI, Chen CC, Chen JC, Su JH, Huang HH, Chen JY, Wu YJ
Marine drugs 2011;9(7):1254-1272
Marine drugs 2011;9(7):1254-1272
An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.
Su CC, Su JH, Lin JJ, Chen CC, Hwang WI, Huang HH, Wu YJ
Marine drugs 2011 Dec;9(12):2622-2642
Marine drugs 2011 Dec;9(12):2622-2642
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15282-1-AP(HSPD1 antibody) at dilution of 1:6000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 15282-1-AP(HSPD1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSP60 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSP60. This antibody recognizes human,mouse,rat antigen. The HSP60 antibody has been validated for the following applications: ELISA, WB, IHC analysis.