66041-1-Ig

antibody from Proteintech Group

Targeting: HSPD1 GroEL, HSP60, SPG13

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

66041-1-Ig

Provider

Proteintech Group

Proper citation

Proteintech Cat#66041-1-Ig, RRID:AB_11041709

Product name

HSP60 antibody

Antibody type

Monoclonal

Description

HSP60 antibody (Cat. #66041-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2F10E7

Vial size

20ul, 150ul

References

Submitted references

HSP60 Regulates Lipid Metabolism in Human Ovarian Cancer.

Li N, Li N, Wen S, Li B, Zhang Y, Liu Q, Zheng S, Yang J, Shen L, Xing L, Zhan X
Oxidative medicine and cellular longevity 2021;2021:6610529

---

Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.

Song Y, Ge X, Chen Y, Hussain T, Liang Z, Dong Y, Wang Y, Tang C, Zhou X
Autophagy 2021 Oct 31;:1-15

---

Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.

Li Z, Xiao Z, Feng Y, Wang Q, Teng M
Photodiagnosis and photodynamic therapy 2021 Oct 17;:102591

---

Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse-induced muscle atrophy.

Yamashita SI, Kyuuma M, Inoue K, Hata Y, Kawada R, Yamabi M, Fujii Y, Sakagami J, Fukuda T, Furukawa K, Tsukamoto S, Kanki T
Journal of cellular physiology 2021 Nov;236(11):7612-7624

---

The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo.

Han S, Zhao F, Hsia J, Ma X, Liu Y, Torres S, Fujioka H, Zhu X
Journal of cell science 2021 Jul 1;134(13)

---

Exogenous Fatty Acids Modulate ER Lipid Composition and Metabolism in Breast Cancer Cells.

Rizzo AM, Colombo I, Montorfano G, Zava S, Corsetto PA
Cells 2021 Jan 16;10(1)

---

ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.

Hu M, Zhou M, Bao X, Pan D, Jiao M, Liu X, Li F, Li CY
The Journal of clinical investigation 2021 Feb 1;131(3)

---

DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke.

Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, Li L, Zhang J, Yu S, Zhao Y
Journal of neuroinflammation 2020 Mar 9;17(1):81

---

Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.

Kalpage HA, Wan J, Morse PT, Lee I, Hüttemann M
Cells 2020 Aug 6;9(8)

---

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.

Wang P, Geng J, Gao J, Zhao H, Li J, Shi Y, Yang B, Xiao C, Linghu Y, Sun X, Chen X, Hong L, Qin F, Li X, Yu JS, You H, Yuan Z, Zhou D, Johnson RL, Chen L
Nature communications 2019 Feb 14;10(1):755

---

Potential urine proteomics biomarkers for primary nephrotic syndrome.

Choi YW, Kim YG, Song MY, Moon JY, Jeong KH, Lee TW, Ihm CG, Park KS, Lee SH
Clinical proteomics 2017;14:18

---

BMI1, a new target of CK2α.

Banerjee Mustafi S, Chakraborty PK, Dwivedi SK, Ding K, Moxley KM, Mukherjee P, Bhattacharya R
Molecular cancer 2017 Mar 7;16(1):56

---

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D
Nature immunology 2015 Nov;16(11):1142-52

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Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.

Hu L, Su C, Song X, Shi Q, Fu J, Xia X, Xu D, Song E, Song Y
Neurotoxicology 2015 Jul;49:149-57

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HeLa cells were subjected to SDS PAGE followed by western blot with 66041-1-Ig(HSPD1 antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of Hela cells, using HSPD1 antibody 66041-1-lg at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human testis using 66041-1-Ig(HSPD1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human testis using 66041-1-Ig(HSPD1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue