Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [124]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 17435-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17435-1-AP, RRID:AB_2035023
- Product name
- Transferrin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Transferrin antibody (Cat. #17435-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Phosphatidylethanolamine Alleviates Osteoarthritis Progression by Inhibiting Oxidative Stress-Induced Chondrocyte Ferroptosis in a Lysosomal-Dependent Manner.
Zha-Chong Shi-San-Wei Pill inhibits ferroptosis in cerebral ischemia via bioinformatics and experimental confirmation methods.
SIRT1 deficiency promotes age-related heart failure through enhancing ferroptosis via GATA4-HADHA-GPX4 axis.
A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor.
Quercetin Attenuates Iron Overload-Induced Renal Injury via Activating Nrf2/xCT/GPX4 Signaling to Inhibit Ferroptosis.
Serum Proteomics of Multiple Menstrual Symptoms in Female Athletes: A Pilot Study.
Proteomics to reveal relationship between menstrual cycle and subjective conditions.
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Metabolic-immune crosstalk in myocardial infarction: RLF and SMCHD1 identified as causal therapeutic targets via integrated lactylation-MR analysis.
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
DIA-based serum proteomics in goat pregnancy: biomarkers & mechanisms.
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
Identification of key ferroptosis-related genes associated with the development of gastric cancer: Prognostic models, molecular mechanisms and potential treatment strategies.
Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice.
HSPA4 restrains transferrin in dopaminergic neurons to attenuate ferroptosis in a Parkinson's disease model.
Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury.
Ferroptotic Pathway Activation in Spermatogonia: A Novel Mechanism of Busulfan-Induced Testicular Injury.
Iron Mediates Radiation-Induced Glioblastoma Cell Diffusion.
TFRC Ablation Induces Insufficient Cartilage Development Through Mitochondrial p53 Translocation-Mediated Ferroptosis.
Functional Characterization of the Hephaestin Variant D568H Provides Novel Mechanistic Insights on Iron-Dependent Asbestos-Induced Carcinogenesis.
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
Transcriptomic analysis of muscle and adipose tissues identifies myokines and adipokines contributing to lipid deposition in Taoyuan Black pigs.
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.
Coagulation Factor XII Is an Antibacterial Protein That Acts Against Bacterial Infection via Its Heavy Chain.
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Regional uterine contractility differences during pregnancy: The role of hypoxia and ferroptosis in vitro.
Targeting symbionts by apolipoprotein L proteins modulates gut immunity.
Myelin-axon interface vulnerability in Alzheimer's disease revealed by subcellular proteomics and imaging of human and mouse brain.
Heat shock protein B1-mediated ferroptosis regulates mitochondrial dysfunction in adipose tissue of ketotic dairy cows.
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma.
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression.
Iron promotes isocitrate dehydrogenase mutant glioma cell motility.
A Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production.
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Lysophosphatidylcholine Acyltransferase 1-Phosphatidylcholine Axis Protects Nucleus Pulposus Cells From Ferroptosis by Facilitating Lysosomal Repair via Interaction With the Endoplasmic Reticulum.
Faecalibacterium prausnitzii prevents age-related heart failure by suppressing ferroptosis in cardiomyocytes through butyrate-mediated LCN2 regulation.
Maimendong decoction and its active ingredient, ophiopogonin D, alleviate bleomycin-induced pulmonary fibrosis by regulating the behavior of lung fibroblasts.
Effect of Self-Assembled Polydopamine Nanoparticles on Ferroptosis in an MPTP-Induced Parkinson's Disease Mice Model.
RAB23 facilitates clathrin-coated nascent vesicle formation at the plasma membrane and modulates cell signaling.
The Cdc42/Rac1 pathway: a molecular mechanism behind iron-deficiency-driven aortic medial degeneration.
Corrigendum: YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Synergistic anti-osteoporosis effects of Anemarrhena asphodeloides bunge-Phellodendron chinense C.K. Schneid herb pair via ferroptosis suppression in ovariectomized mice.
Iron-depleting nutritional immunity controls extracellular bacterial replication in Legionella pneumophila infections.
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.
Gallium Uncouples Iron Metabolism to Enhance Glioblastoma Radiosensitivity.
Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.
SAT1/ALOX15 Signaling Pathway Is Involved in Ferroptosis After Skeletal Muscle Contusion.
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner.
Mitochondrial Iron Metabolism as a Potential Key Mediator of PD-L1 Thermal Regulation.
Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop.
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Characterization of the proteome of stable and unstable carotid atherosclerotic plaques using data-independent acquisition mass spectrometry.
The TF/Nrf2/GSTP1 pathway is involved in stress-induced hepatocellular injury through ferroptosis.
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.
Epithelial Membrane Protein 2 (EMP2) Blockade Attenuates Pathological Neovascularization in Murine Oxygen-Induced Retinopathy.
β-eudesmol inhibits cell proliferation and induces ferroptosis via regulating MAPK signaling pathway in breast cancer.
Magnetic graphene oxide nanocomposites induce cytotoxicity in ADSCs via GPX4 regulating ferroptosis.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
7-Dehydrocholesterol dictates ferroptosis sensitivity.
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4.
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction.
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction.
Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Intra-host Trypanosoma cruzi strain dynamics shape disease progression: the missing link in Chagas disease pathogenesis.
Western blot and immunohistochemical analysis of mouse tissue factor.
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Continuously increased generation of ROS in human plasma after cardiac arrest as determined by Amplex Red oxidation.
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.
Transgelin promotes ferroptosis to inhibit the malignant progression of esophageal squamous cell carcinoma.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Opening K(ATP) channels induces inflammatory tolerance and prevents chronic pain.
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier.
Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier.
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Myelin regulatory factor is a target of individual and interactive effects of HIV-1 Tat and morphine in the striatum and pre-frontal cortex.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
ATP5O Hypo-crotonylation Caused by HDAC2 Hyper-Phosphorylation Is a Primary Detrimental Factor for Downregulated Phospholipid Metabolism under Chronic Stress.
The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells.
Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis.
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Precise Investigation of the Efficacy of Multicomponent Drugs Against Pneumonia Infected With Influenza Virus.
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood-brain barrier and attenuates their targeting ability to brain tumor.
Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models.
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements.
Tumor cell-imposed iron restriction drives immunosuppressive polarization of tumor-associated macrophages.
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice.
Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production.
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess.
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Dysregulated expression of antioxidant enzymes in polyethylene particle-induced periprosthetic inflammation and osteolysis.
NF-κB p65 Knock-down inhibits TF, PAI-1 and promotes activated protein C production in lipopolysaccharide-stimulated alveolar epithelial cells type II.
Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.
Lipid A-activated inducible nitric oxide synthase expression via nuclear factor-κB in mouse choroid plexus cells.
Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.
CXCR7 correlates with the differentiation of hepatocellular carcinoma and suppresses HNF4α expression through the ERK pathway.
Investigating the role of transferrin in the distribution of iron, manganese, copper, and zinc.
Zheng H, Zhu Z, Zhu J, Chen D, Ruan R, Ning R
International journal of general medicine 2026;19:581128
International journal of general medicine 2026;19:581128
Zha-Chong Shi-San-Wei Pill inhibits ferroptosis in cerebral ischemia via bioinformatics and experimental confirmation methods.
Shang J, Chen W, Wei W, Wang B, Song Q, Bai M, Liu X
Journal of ethnopharmacology 2026 May 23;363:121402
Journal of ethnopharmacology 2026 May 23;363:121402
SIRT1 deficiency promotes age-related heart failure through enhancing ferroptosis via GATA4-HADHA-GPX4 axis.
Duan Y, Luo Y, Han X, Yu H, Liu H, Zhou Y, Gao Y, Xu Q, Wei Y, Min R, Hong Y, Ji X, Jia H, Li Y, Zhang Y
Cell death & disease 2026 Mar 23;17(1)
Cell death & disease 2026 Mar 23;17(1)
A paraventricular hypothalamic control of social stress susceptibility by targeting brown adipose tissue β3 adrenoceptor.
Du X, Zhang J, Wang Q, Zhou D, Zhang W, Song L, Cui M, Ge T, Zhai X, Yu Y, Yang J, Hu A, Zhang H, Cao JL, Wu Z
Communications biology 2026 Jan 23;9(1)
Communications biology 2026 Jan 23;9(1)
Quercetin Attenuates Iron Overload-Induced Renal Injury via Activating Nrf2/xCT/GPX4 Signaling to Inhibit Ferroptosis.
Wang X, Li W, Yuan W, Wei Z, Yang Z, Zhang Z, Sun Z, Ji G, Hu H
Life (Basel, Switzerland) 2026 Feb 25;16(3)
Life (Basel, Switzerland) 2026 Feb 25;16(3)
Serum Proteomics of Multiple Menstrual Symptoms in Female Athletes: A Pilot Study.
Fushimi K, Kondo T, Ikegami N, Yamada M, Wong SY, Sakamaki-Sunaga M, Hayashi N
FASEB bioAdvances 2026 Apr;8:e70109
FASEB bioAdvances 2026 Apr;8:e70109
Proteomics to reveal relationship between menstrual cycle and subjective conditions.
Fushimi K, Kondo T, Ikegami N, Yamada M, Wong SY, Sakamaki-Sunaga M, Hayashi N
Scientific reports 2026 Apr 15;
Scientific reports 2026 Apr 15;
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Fang P, Li S, Lu ZQ, Xia DL, Xu MM, Pan JJ, Fu L, Sun GY, You QH
Burns & trauma 2025;13:tkaf056
Burns & trauma 2025;13:tkaf056
Metabolic-immune crosstalk in myocardial infarction: RLF and SMCHD1 identified as causal therapeutic targets via integrated lactylation-MR analysis.
Tang J, Yuan L, Han YL
Frontiers in cell and developmental biology 2025;13:1653551
Frontiers in cell and developmental biology 2025;13:1653551
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Luis DD, Liehr T, Kankel S, Weise A, Pentzold C, Buhl EM, Hardt KS, Keller DT, Schröder-Lange SK, Weiskirchen R
Frontiers in cell and developmental biology 2025;13:1648639
Frontiers in cell and developmental biology 2025;13:1648639
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Song Y, Hai E, He L, Zhang N, Zhang N, Wang J, Sun Y, Zeng D, Zhang J
Frontiers in cell and developmental biology 2025;13:1610621
Frontiers in cell and developmental biology 2025;13:1610621
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
Wu Y, Li J, Zhai W, Liu W, Wu H, Liu H, Min J, Wang F, Liu JX
Neurobiology of disease 2025 Sep;213:107027
Neurobiology of disease 2025 Sep;213:107027
DIA-based serum proteomics in goat pregnancy: biomarkers & mechanisms.
Xu D, Wang D, Zhou L, Huang Z, Sun M, Cao X, Zhou J, Gao X, He J, Zhao J, Li H
Research in veterinary science 2025 Sep;193:105815
Research in veterinary science 2025 Sep;193:105815
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
Zhang F, Cui D, Wang Z, Li Y, Wang K, Lu H, Yu H, Jiao W, Cui X
Inflammation 2025 Oct;48(5):3111-3129
Inflammation 2025 Oct;48(5):3111-3129
Identification of key ferroptosis-related genes associated with the development of gastric cancer: Prognostic models, molecular mechanisms and potential treatment strategies.
Wang H, Chen H, Liu J, Zhang D, Wang D, Huang M, Li M, He S, Ma L
Oncology letters 2025 Oct;30(4):450
Oncology letters 2025 Oct;30(4):450
Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice.
Lu S, Khan MA, Setua S, O'Boyle Q, Thangaraju K, Cabrales P, Swindle DC, Irwin DC, Buehler PW, Palmer AF
Biotechnology and bioengineering 2025 Oct;122(10):2709-2723
Biotechnology and bioengineering 2025 Oct;122(10):2709-2723
HSPA4 restrains transferrin in dopaminergic neurons to attenuate ferroptosis in a Parkinson's disease model.
Gao T, Wei H, Ju Q, Lin Y, Yin X, Liu X, Shen J, Ji Q, Sun C, Shen L
Communications biology 2025 Oct 9;8(1):1453
Communications biology 2025 Oct 9;8(1):1453
Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis.
Puri C, Park SJ, Wrobel L, Rubinsztein DC
Developmental cell 2025 Oct 20;60(20):2715-2729.e8
Developmental cell 2025 Oct 20;60(20):2715-2729.e8
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury.
Liu Y, Wang Q, Hou Z, Gao Y, Li P
Journal of molecular neuroscience : MN 2025 May 3;75(2):63
Journal of molecular neuroscience : MN 2025 May 3;75(2):63
Ferroptotic Pathway Activation in Spermatogonia: A Novel Mechanism of Busulfan-Induced Testicular Injury.
Hu H, Yuan W, Wang Y, Dong Z, Chen G
Biology 2025 May 23;14(6)
Biology 2025 May 23;14(6)
Iron Mediates Radiation-Induced Glioblastoma Cell Diffusion.
Owusu SB, Ekanayake AB, Tivanski AV, Petronek MS
International journal of molecular sciences 2025 May 16;26(10)
International journal of molecular sciences 2025 May 16;26(10)
TFRC Ablation Induces Insufficient Cartilage Development Through Mitochondrial p53 Translocation-Mediated Ferroptosis.
Wang Y, Wen X, Guo Y, Wang Y, Gu Y
International journal of molecular sciences 2025 Mar 18;26(6)
International journal of molecular sciences 2025 Mar 18;26(6)
Functional Characterization of the Hephaestin Variant D568H Provides Novel Mechanistic Insights on Iron-Dependent Asbestos-Induced Carcinogenesis.
Zacchi P, Longo F, Marconato A, Amadei M, Bonaccorsi di Patti MC, Avolio E, Li P, Fan H, Tetley TD, Zabucchi G, Borelli V
International journal of molecular sciences 2025 Mar 13;26(6)
International journal of molecular sciences 2025 Mar 13;26(6)
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
Xu J, Cai Z, Pang Z, Chen J, Zhu K, Wang D, Tu J
International journal of molecular sciences 2025 Mar 10;26(6)
International journal of molecular sciences 2025 Mar 10;26(6)
Transcriptomic analysis of muscle and adipose tissues identifies myokines and adipokines contributing to lipid deposition in Taoyuan Black pigs.
Guo L, Xu J, Zhou W, Chen S, Shi H, Han M, Pang W, Yin Y, Li F
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Jun;21:256-266
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Jun;21:256-266
OTUB1-SLC7A11 Axis Mediates 4-Octyl Itaconate Protection Against Acetaminophen-Induced Ferroptotic Liver Injury.
Hu Z, Li Y, Xu D, Meng H, Liu W, Xu Q, Yao B, Wang J
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
Antioxidants (Basel, Switzerland) 2025 Jun 9;14(6)
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Wei Z, Bai B, Zheng Y, Wang H, Zhang M, Zhang Q, Li X
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.
Yuan W, Ji G, Wang X, Li W, Sun Z, Wei Z, Shi X, Hu H
Journal of agricultural and food chemistry 2025 Jun 25;73(25):15579-15595
Journal of agricultural and food chemistry 2025 Jun 25;73(25):15579-15595
Coagulation Factor XII Is an Antibacterial Protein That Acts Against Bacterial Infection via Its Heavy Chain.
Liu J, Wang D, Pan S, Song X
International journal of molecular sciences 2025 Jun 23;26(13)
International journal of molecular sciences 2025 Jun 23;26(13)
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Liu Y, Yu J, Hu H, Pu S, Wu H, Ma Y, Yang W, Fang C, Sun F, Wang H
Aging 2025 Jun 2;17(6):1386-1404
Aging 2025 Jun 2;17(6):1386-1404
Regional uterine contractility differences during pregnancy: The role of hypoxia and ferroptosis in vitro.
Tian R, Li X, Su J, Yu H, Fei J, Xu C, Du X, Yu B, Cao Y, Yin Z
Life sciences 2025 Jun 15;371:123603
Life sciences 2025 Jun 15;371:123603
Targeting symbionts by apolipoprotein L proteins modulates gut immunity.
Yang T, Hu X, Cao F, Yun F, Jia K, Zhang M, Kong G, Nie B, Liu Y, Zhang H, Li X, Gao H, Shi J, Liang G, Hu G, Kasper DL, Song X, Qian Y
Nature 2025 Jul;643(8070):210-218
Nature 2025 Jul;643(8070):210-218
Myelin-axon interface vulnerability in Alzheimer's disease revealed by subcellular proteomics and imaging of human and mouse brain.
Cai Y, Pinheiro-de-Sousa I, Slobodyanyuk M, Chen F, Huynh T, Kanyo J, Tang P, Fuentes LA, Braker A, Welch R, Huttner A, Tong L, Yuan P, Lam TT, Petsalaki E, Reimand J, Nairn AC, Grutzendler J
Nature neuroscience 2025 Jul;28(7):1418-1435
Nature neuroscience 2025 Jul;28(7):1418-1435
Heat shock protein B1-mediated ferroptosis regulates mitochondrial dysfunction in adipose tissue of ketotic dairy cows.
Fan Y, Ma L, Xu X, Fang X, Mauck J, Loor JJ, Sun X, Jia H, Xu C, Xu Q
Journal of dairy science 2025 Jul;108(7):7815-7836
Journal of dairy science 2025 Jul;108(7):7815-7836
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Wang S, Zhu L, Wang Y, Han Y, Wang Q, Yang W, Zhao L, Zhang Y, Pei D, Huang W, Jin A, Lin Z, Piao J
Cell death & disease 2025 Jul 23;16(1):549
Cell death & disease 2025 Jul 23;16(1):549
Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma.
Li A, Gong Z, Long Y, Li Y, Liu C, Lu X, Li Q, He X, Lu H, Wu K, Nie Y, Tan J, Ye J, You H
Developmental cell 2025 Jul 21;60(14):1974-1990.e11
Developmental cell 2025 Jul 21;60(14):1974-1990.e11
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression.
Wang M, Wen X, Feng Z, Choubey M, Chen S, Pan R, Gong K, Tirumalasetty MB, Gao F, Liao C, Yin Z, Zhang S, He Y, Chen H, Cao Y, Miao QR, Hu W, Duan Y
Nature communications 2025 Jul 1;16(1):5491
Nature communications 2025 Jul 1;16(1):5491
Iron promotes isocitrate dehydrogenase mutant glioma cell motility.
Owusu SB, Russell E, Ekanayake AB, Tivanski AV, Petronek MS
Free radical biology & medicine 2025 Jan;226:109-116
Free radical biology & medicine 2025 Jan;226:109-116
A Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.
Wang J, Li M, Zhao B, Chang R, Wu W, Zhang H, Usman M, Loor JJ, Xu C
Journal of agricultural and food chemistry 2025 Jan 8;73(1):549-561
Journal of agricultural and food chemistry 2025 Jan 8;73(1):549-561
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
Fan Y, Ren Y, Deng L, Lv D, Chen J, Ling Y, Tu J, Xu X, Wang D, Cai Z
International immunopharmacology 2025 Jan 10;144:113641
International immunopharmacology 2025 Jan 10;144:113641
MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production.
Yang X, Liu J, Yin Y, Yang L, Gao M, Wu Z, Lu B, Luo S, Wang W, Li R
Ecotoxicology and environmental safety 2025 Jan 1;289:117654
Ecotoxicology and environmental safety 2025 Jan 1;289:117654
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Zheng F, Lei JZ, Wang JX, Xu XY, Zhou B, Ge R, Dai M, Dong HK, Wu N, Li YH, Zhu GQ, Zhou YB
Free radical biology & medicine 2025 Feb 1;227:296-311
Free radical biology & medicine 2025 Feb 1;227:296-311
Lysophosphatidylcholine Acyltransferase 1-Phosphatidylcholine Axis Protects Nucleus Pulposus Cells From Ferroptosis by Facilitating Lysosomal Repair via Interaction With the Endoplasmic Reticulum.
Li C, Jiang J, Tu S, Dong Y, Zhang W, Chen X
Neurospine 2025 Dec;22(4):953-973
Neurospine 2025 Dec;22(4):953-973
Faecalibacterium prausnitzii prevents age-related heart failure by suppressing ferroptosis in cardiomyocytes through butyrate-mediated LCN2 regulation.
Zhang Y, Wei Y, Han X, Shi L, Yu H, Ji X, Gao Y, Gao Q, Zhang L, Duan Y, Li W, Yuan Y, Shi J, Cheng L, Li Y
Gut microbes 2025 Dec;17(1):2505119
Gut microbes 2025 Dec;17(1):2505119
Maimendong decoction and its active ingredient, ophiopogonin D, alleviate bleomycin-induced pulmonary fibrosis by regulating the behavior of lung fibroblasts.
Yang M, Zhang X, Bao S, Yang S, Zhang Y, Liu Y, Li C, Zou J, Li J, Yan S
Chinese medicine 2025 Aug 29;20(1):135
Chinese medicine 2025 Aug 29;20(1):135
Effect of Self-Assembled Polydopamine Nanoparticles on Ferroptosis in an MPTP-Induced Parkinson's Disease Mice Model.
Xu Q, Xie D, Qie X, Chi B, Liu H
ACS applied bio materials 2025 Aug 18;8(8):7410-7419
ACS applied bio materials 2025 Aug 18;8(8):7410-7419
RAB23 facilitates clathrin-coated nascent vesicle formation at the plasma membrane and modulates cell signaling.
Hasan MR, Takatalo M, Nieminen P, Rice R, Mustonen T, Rice DP
Cellular and molecular life sciences : CMLS 2025 Apr 22;82(1):171
Cellular and molecular life sciences : CMLS 2025 Apr 22;82(1):171
The Cdc42/Rac1 pathway: a molecular mechanism behind iron-deficiency-driven aortic medial degeneration.
Wang S, Liu H, Hu J, Li T, Li B
American journal of translational research 2024;16(8):3922-3937
American journal of translational research 2024;16(8):3922-3937
Corrigendum: YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Jing-Lun Z, Shuang C, Li-Mei Z, Xiao-Dong L
Frontiers in pharmacology 2024;15:1395496
Frontiers in pharmacology 2024;15:1395496
Synergistic anti-osteoporosis effects of Anemarrhena asphodeloides bunge-Phellodendron chinense C.K. Schneid herb pair via ferroptosis suppression in ovariectomized mice.
Deng X, Xiao W, Lin B, Wang F, Song L, Wang N
Frontiers in pharmacology 2024;15:1378634
Frontiers in pharmacology 2024;15:1378634
Iron-depleting nutritional immunity controls extracellular bacterial replication in Legionella pneumophila infections.
Torres-Escobar A, Wilkins A, Juárez-Rodríguez MD, Circu M, Latimer B, Dragoi AM, Ivanov SS
Nature communications 2024 Sep 8;15(1):7848
Nature communications 2024 Sep 8;15(1):7848
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.
Ong HW, Yang X, Smith JL, Taft-Benz S, Howell S, Dickmander RJ, Havener TM, Sanders MK, Brown JW, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM
Molecules (Basel, Switzerland) 2024 Sep 2;29(17)
Molecules (Basel, Switzerland) 2024 Sep 2;29(17)
Gallium Uncouples Iron Metabolism to Enhance Glioblastoma Radiosensitivity.
Owusu SB, Zaher A, Ahenkorah S, Pandya DN, Wadas TJ, Petronek MS
International journal of molecular sciences 2024 Sep 18;25(18)
International journal of molecular sciences 2024 Sep 18;25(18)
Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.
Prajapati M, Chiu L, Zhang JZ, Chong GS, DaSilva NA, Bartnikas TB
Metallomics : integrated biometal science 2024 Oct 4;16(10)
Metallomics : integrated biometal science 2024 Oct 4;16(10)
SAT1/ALOX15 Signaling Pathway Is Involved in Ferroptosis After Skeletal Muscle Contusion.
Yang H, Li Y, Zhu W, Feng X, Xin H, Chen H, Zhang G, Zuo M, Cong B, Shi W
International journal of molecular sciences 2024 Oct 21;25(20)
International journal of molecular sciences 2024 Oct 21;25(20)
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner.
Yang BL, Long YY, Lei Q, Gao F, Ren WX, Cao YL, Wu D, Xu LY, Qu J, Li H, Yu YL, Zhang AY, Wang S, Wang HX, Chen ZC, Li QB
Acta pharmacologica Sinica 2024 Nov;45(11):2300-2312
Acta pharmacologica Sinica 2024 Nov;45(11):2300-2312
Mitochondrial Iron Metabolism as a Potential Key Mediator of PD-L1 Thermal Regulation.
Keeler G, Owusu SB, Zanaty M, Petronek MS
Cancers 2024 Nov 5;16(22)
Cancers 2024 Nov 5;16(22)
Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop.
Shang J, Jiao J, Wang J, Yan M, Li Q, Shabuerjiang L, Huang G, Song Q, Wen Y, Zhang X, Wu K, Cui Y, Liu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116500
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116500
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L
British journal of cancer 2024 Mar;130(5):755-768
British journal of cancer 2024 Mar;130(5):755-768
Characterization of the proteome of stable and unstable carotid atherosclerotic plaques using data-independent acquisition mass spectrometry.
Lai Z, Wang C, Liu X, Sun H, Guo Z, Shao J, Li K, Chen J, Wang J, Lei X, Shu K, Feng Y, Kong D, Sun W, Liu B
Journal of translational medicine 2024 Mar 7;22(1):247
Journal of translational medicine 2024 Mar 7;22(1):247
The TF/Nrf2/GSTP1 pathway is involved in stress-induced hepatocellular injury through ferroptosis.
Tian X, Li Y, Lei L, Feng X, Xin H, Chen H, Zhang G, Zuo M, Shi W, Cong B
Journal of cellular and molecular medicine 2024 Jun;28(12):e18494
Journal of cellular and molecular medicine 2024 Jun;28(12):e18494
GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Chen B, Fu W, Jie C, Zhang G, Li Z, Liu Y, Zhou S
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
Chen Y, Bao S, Wang Z, Fang Z, Tang H
European journal of medical research 2024 Jul 26;29(1):387
European journal of medical research 2024 Jul 26;29(1):387
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.
Ong HW, Yang X, Smith JL, Dickmander RJ, Brown JW, Havener TM, Taft-Benz S, Howell S, Sanders MK, Capener JL, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM
Journal of medicinal chemistry 2024 Jul 25;67(14):12261-12313
Journal of medicinal chemistry 2024 Jul 25;67(14):12261-12313
Epithelial Membrane Protein 2 (EMP2) Blockade Attenuates Pathological Neovascularization in Murine Oxygen-Induced Retinopathy.
Aguirre B, Lin MC, Araujo E, Lu CH, Casero D, Sun M, Nusinowitz S, Hanson J, Calkins K, Gordon L, Wadehra M, Chu A
Investigative ophthalmology & visual science 2024 Jul 1;65(8):10
Investigative ophthalmology & visual science 2024 Jul 1;65(8):10
β-eudesmol inhibits cell proliferation and induces ferroptosis via regulating MAPK signaling pathway in breast cancer.
Li Z, Li J, Liu X, Liu Y, Chen H, Sun X
Toxicon : official journal of the International Society on Toxinology 2024 Jan;237:107529
Toxicon : official journal of the International Society on Toxinology 2024 Jan;237:107529
Magnetic graphene oxide nanocomposites induce cytotoxicity in ADSCs via GPX4 regulating ferroptosis.
He Y, Shi F, Hu J, Li H, Chen X, Yuan L, Lu Y, Du W, Li R, Wu J, Deng F, Yu D
Ecotoxicology and environmental safety 2024 Jan 1;269:115745
Ecotoxicology and environmental safety 2024 Jan 1;269:115745
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
7-Dehydrocholesterol dictates ferroptosis sensitivity.
Li Y, Ran Q, Duan Q, Jin J, Wang Y, Yu L, Wang C, Zhu Z, Chen X, Weng L, Li Z, Wang J, Wu Q, Wang H, Tian H, Song S, Shan Z, Zhai Q, Qin H, Chen S, Fang L, Yin H, Zhou H, Jiang X, Wang P
Nature 2024 Feb;626(7998):411-418
Nature 2024 Feb;626(7998):411-418
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
Hao J, Lu M, Zhao X, Li C, Ge C, Zhang J, Tu L, Zhang Q
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4.
Chen Y, Guan S, Liu M, Lang L, Peng H, Lu J
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26859-26873
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26859-26873
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
Sun X, Yang S, He Z, Wang L, He J
Chinese medicine 2024 Dec 18;19(1):170
Chinese medicine 2024 Dec 18;19(1):170
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Pan C, Wang K, Hong R, Wang X, Zhang Y, Fan Z, Shi Y, Liu T, Chen H
Environmental research 2024 Dec 15;263(Pt 2):120098
Environmental research 2024 Dec 15;263(Pt 2):120098
Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction.
Guo D, Yang X, Yu R, Geng J, Zhang X, Wang Y, Liang Q, Pu S, Peng T, Liu M, Fu F, Li Z, Hu L, Li Y
Journal of nanobiotechnology 2024 Aug 31;22(1):527
Journal of nanobiotechnology 2024 Aug 31;22(1):527
Human umbilical cord mesenchymal stem cells alleviate chemotherapy-induced premature ovarian insufficiency mouse model by suppressing ferritinophagy-mediated ferroptosis in granulosa cells.
Dai W, Xu B, Ding L, Zhang Z, Yang H, He T, Liu L, Pei X, Fu X
Free radical biology & medicine 2024 Aug 1;220:1-14
Free radical biology & medicine 2024 Aug 1;220:1-14
YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.
Jing-Lun Z, Shuang C, Li-Mei Z, Xiao-Dong L
Frontiers in pharmacology 2023;14:1205062
Frontiers in pharmacology 2023;14:1205062
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction.
Ye T, Yang W, Gao T, Yu X, Chen T, Yang Y, Guo J, Li Q, Li H, Yang L
Free radical biology & medicine 2023 Sep;206:143-161
Free radical biology & medicine 2023 Sep;206:143-161
Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification.
He S, He X, Pan S, Jiang W
Molecules (Basel, Switzerland) 2023 Sep 19;28(18)
Molecules (Basel, Switzerland) 2023 Sep 19;28(18)
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Intra-host Trypanosoma cruzi strain dynamics shape disease progression: the missing link in Chagas disease pathogenesis.
Dumonteil E, Desale H, Tu W, Hernandez-Cuevas N, Shroyer M, Goff K, Marx PA, Herrera C
Microbiology spectrum 2023 Oct 17;11(5):e0423622
Microbiology spectrum 2023 Oct 17;11(5):e0423622
Western blot and immunohistochemical analysis of mouse tissue factor.
Mackman N, Hisada Y, Park JA
Research and practice in thrombosis and haemostasis 2023 Nov;7(8):102249
Research and practice in thrombosis and haemostasis 2023 Nov;7(8):102249
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Liu H, He Y, Gao X, Li T, Qiao B, Tang L, Lan J, Su Q, Ruan Z, Tang Z, Hu L
Mycotoxin research 2023 Nov;39(4):437-451
Mycotoxin research 2023 Nov;39(4):437-451
Continuously increased generation of ROS in human plasma after cardiac arrest as determined by Amplex Red oxidation.
Shoaib M, Kim N, Choudhary RC, Espin B, Nishikimi M, Iverson A, Yagi T, Marashi Shoshtari SS, Shinozaki K, Becker LB, Kim J
Free radical research 2023 May;57(5):384-394
Free radical research 2023 May;57(5):384-394
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.
Kessel JC, Weiskirchen R, Schröder SK
International journal of molecular sciences 2023 May 25;24(11)
International journal of molecular sciences 2023 May 25;24(11)
Transgelin promotes ferroptosis to inhibit the malignant progression of esophageal squamous cell carcinoma.
Chen Q, Zhang L, Wan C, Yang B, Kong X, Xu X, Gu Y, Wang C, Liu X, Ding Q, Zhu L, Li Y, Wang B, Zhong W
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
SATB1/SLC7A11/HO-1 Axis Ameliorates Ferroptosis in Neuron Cells After Ischemic Stroke by Danhong Injection.
Zhan S, Liang J, Lin H, Cai J, Yang X, Wu H, Wei J, Wang S, Xian M
Molecular neurobiology 2023 Jan;60(1):413-427
Molecular neurobiology 2023 Jan;60(1):413-427
Opening K(ATP) channels induces inflammatory tolerance and prevents chronic pain.
Qian C, Fan Y, Zong L, Miao C, Ji LL, Wan L, Jia R, Qin X, Wang Y, Wu Q, Tao XY, Hao L, Hu L, Liu WT
Brain, behavior, and immunity 2023 Jan;107:76-86
Brain, behavior, and immunity 2023 Jan;107:76-86
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier.
Baringer S, Palsa K, Simpson IA, Connor JR
Research square 2023 Jan 17;
Research square 2023 Jan 17;
Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.
Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S
Proceedings of the National Academy of Sciences of the United States of America 2023 Jan 10;120(2):e2212644120
Proceedings of the National Academy of Sciences of the United States of America 2023 Jan 10;120(2):e2212644120
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier.
Baringer SL, Palsa K, Simpson IA, Connor JR
bioRxiv : the preprint server for biology 2023 Jan 10;
bioRxiv : the preprint server for biology 2023 Jan 10;
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Liu C, Tian Q, Wang J, He P, Han S, Guo Y, Yang C, Wang G, Wei H, Li M
Molecular neurobiology 2023 Feb;60(2):460-479
Molecular neurobiology 2023 Feb;60(2):460-479
Myelin regulatory factor is a target of individual and interactive effects of HIV-1 Tat and morphine in the striatum and pre-frontal cortex.
Flounlacker KM, Hahn YK, Xu R, Simons CA, Tian T, Hauser KF, Knapp PE
Journal of neurovirology 2023 Feb;29(1):15-26
Journal of neurovirology 2023 Feb;29(1):15-26
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
Nox4-and Tf/TfR-mediated peroxidation and iron overload exacerbate neuronal ferroptosis after intracerebral hemorrhage: Involvement of EAAT3 dysfunction.
Xie J, Lv H, Liu X, Xia Z, Li J, Hong E, Ding B, Zhang W, Chen Y
Free radical biology & medicine 2023 Apr;199:67-80
Free radical biology & medicine 2023 Apr;199:67-80
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
ATP5O Hypo-crotonylation Caused by HDAC2 Hyper-Phosphorylation Is a Primary Detrimental Factor for Downregulated Phospholipid Metabolism under Chronic Stress.
Chen LJ, Tu ZY, Wang Y, He YH, Wang X, Tao SZ, Xu YY, Li CR, Wang RL, Yang ZX, Sun J, Ma X, Zhang D
Research (Washington, D.C.) 2022;2022:9834963
Research (Washington, D.C.) 2022;2022:9834963
The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells.
Liu F, Cai Z, Yang Y, Plasko G, Zhao P, Wu X, Tang C, Li D, Li T, Hu S, Song L, Yu S, Xu R, Luo H, Fan L, Wang E, Xiao Z, Ji Y, Zeng R, Li R, Bai J, Zhou Z, Liu F, Zhang J
Science advances 2022 Sep 23;8(38):eabq1799
Science advances 2022 Sep 23;8(38):eabq1799
Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis.
Lv Z, Han J, Li J, Guo H, Fei Y, Sun Z, Dong J, Wang M, Fan C, Li W, Xie Y, Sun W, Chen J, Liu Y, Chen F, Liu Z, Liu A, Wu R, Xu X, Yan W, Jiang Q, Ikegawa S, Chen X, Shi D
EBioMedicine 2022 Oct;84:104258
EBioMedicine 2022 Oct;84:104258
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Hou Y, Wang S, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Yang G
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Precise Investigation of the Efficacy of Multicomponent Drugs Against Pneumonia Infected With Influenza Virus.
Wei J, Sun J, Zeng J, Ji E, Xu J, Tang C, Huo H, Zhang Y, Li H, Yang H
Frontiers in pharmacology 2021;12:604009
Frontiers in pharmacology 2021;12:604009
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood-brain barrier and attenuates their targeting ability to brain tumor.
Xiao W, Wang Y, Zhang H, Liu Y, Xie R, He X, Zhou Y, Liang L, Gao H
Biomaterials 2021 Jul;274:120888
Biomaterials 2021 Jul;274:120888
Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models.
Wu Y, Johnson G, Zhao F, Wu Y, Zhao G, Brown A, You S, Zou MH, Song P
International journal of molecular sciences 2021 Jul 31;22(15)
International journal of molecular sciences 2021 Jul 31;22(15)
Role of ferroptosis induced by a high concentration of calcium oxalate in the formation and development of urolithiasis.
He Z, Liao W, Song Q, Li B, Liu J, Xiong Y, Song C, Yang S
International journal of molecular medicine 2021 Jan;47(1):289-301
International journal of molecular medicine 2021 Jan;47(1):289-301
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Li B, Wang Z, Hong J, Che Y, Chen R, Hu Z, Hu X, Wu Q, Hu J, Zhang M
Clinical and translational medicine 2021 Jan;11(1):e276
Clinical and translational medicine 2021 Jan;11(1):e276
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements.
Zhang Q, Lu XM, Zhang M, Yang CY, Lv SY, Li SF, Zhong CY, Geng SS
Scientific reports 2021 Jan 14;11(1):1347
Scientific reports 2021 Jan 14;11(1):1347
Tumor cell-imposed iron restriction drives immunosuppressive polarization of tumor-associated macrophages.
Sun JL, Zhang NP, Xu RC, Zhang GC, Liu ZY, Abuduwaili W, Wang F, Yu XN, Shi X, Song GQ, Wu H, Liu TT, Shen XZ, Deng B, Weng SQ, Dong L, Zhu JM
Journal of translational medicine 2021 Aug 13;19(1):347
Journal of translational medicine 2021 Aug 13;19(1):347
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438
Archives of pharmacal research 2021 Apr;44(4):427-438
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L
Frontiers in neuroscience 2020;14:925
Frontiers in neuroscience 2020;14:925
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Shi Y, Lam SM, Liu H, Luo G, Zhang J, Yao S, Li J, Zheng L, Xu N, Zhang X, Shui G
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice.
Shi Y, Liu H, Liu H, Yu Y, Zhang J, Li Y, Luo G, Zhang X, Xu N
Molecular medicine reports 2020 Oct;22(4):3117-3126
Molecular medicine reports 2020 Oct;22(4):3117-3126
Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production.
Rossi G, Dufrusine B, Lizzi AR, Luzi C, Piccoli A, Fezza F, Iorio R, D'Andrea G, Dainese E, Cecconi S, Maccarrone M
International journal of molecular sciences 2020 Nov 26;21(23)
International journal of molecular sciences 2020 Nov 26;21(23)
Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation.
Weber RA, Yen FS, Nicholson SPV, Alwaseem H, Bayraktar EC, Alam M, Timson RC, La K, Abu-Remaileh M, Molina H, Birsoy K
Molecular cell 2020 Feb 6;77(3):645-655.e7
Molecular cell 2020 Feb 6;77(3):645-655.e7
The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells.
Wang Q, Wang HX, Shen JY, Zhang R, Hong JW, Li Z, Chen G, Li MX, Ding Z, Li J, Zhang JP, Zhang MR, Xu LC
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Ecotoxicology and environmental safety 2019 Aug 15;177:58-65
Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess.
Mercadante CJ, Prajapati M, Parmar JH, Conboy HL, Dash ME, Pettiglio MA, Herrera C, Bu JT, Stopa EG, Mendes P, Bartnikas TB
Haematologica 2019 Apr;104(4):678-689
Haematologica 2019 Apr;104(4):678-689
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, Li H
Cell & bioscience 2018;8:41
Cell & bioscience 2018;8:41
Dysregulated expression of antioxidant enzymes in polyethylene particle-induced periprosthetic inflammation and osteolysis.
Peng KT, Tsai MH, Lee CW, Chiang YC, Chen PC, Chen CC, Chang CH, Shih HN, Chang PJ
PloS one 2018;13(8):e0202501
PloS one 2018;13(8):e0202501
NF-κB p65 Knock-down inhibits TF, PAI-1 and promotes activated protein C production in lipopolysaccharide-stimulated alveolar epithelial cells type II.
Liu B, Wu Y, Wang Y, Cheng Y, Yao L, Liu Y, Qian H, Yang H, Shen F
Experimental lung research 2018 May-Jun;44(4-5):241-251
Experimental lung research 2018 May-Jun;44(4-5):241-251
Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice.
Liu Y, Su X, Hao J, Chen M, Liu W, Liao X, Li G
International journal of molecular sciences 2016 Jan 13;17(1)
International journal of molecular sciences 2016 Jan 13;17(1)
Lipid A-activated inducible nitric oxide synthase expression via nuclear factor-κB in mouse choroid plexus cells.
Takano M, Ohkusa M, Otani M, Min KS, Kadoyama K, Minami K, Sano K, Matsuyama S
Immunology letters 2015 Oct;167(2):57-62
Immunology letters 2015 Oct;167(2):57-62
Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.
Patil H, Saha A, Senda E, Cho KI, Haque M, Yu M, Qiu S, Yoon D, Hao Y, Peachey NS, Ferreira PA
The Journal of biological chemistry 2014 Oct 24;289(43):29767-89
The Journal of biological chemistry 2014 Oct 24;289(43):29767-89
CXCR7 correlates with the differentiation of hepatocellular carcinoma and suppresses HNF4α expression through the ERK pathway.
Xue TC, Jia QA, Bu Y, Chen RX, Cui JF, Tang ZY, Ye SL
Oncology reports 2014 Dec;32(6):2387-96
Oncology reports 2014 Dec;32(6):2387-96
Investigating the role of transferrin in the distribution of iron, manganese, copper, and zinc.
Herrera C, Pettiglio MA, Bartnikas TB
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2014 Aug;19(6):869-77
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2014 Aug;19(6):869-77
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 17435-1-AP(TF antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 17435-1-AP(TF antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Transferrin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Transferrin. This antibody recognizes human, mouse, rat antigen. The Transferrin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
