Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- GTX21223 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX21223, RRID:AB_374305
- Product name
- Transferrin antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Bovine
- Host
- Rabbit
Submitted references TNF-α exerts potent anti-rotavirus effects via the activation of classical NF-κB pathway.
Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders.
Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease.
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution.
A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.
Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains.
Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders.
Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis.
Abnormal brain iron homeostasis in human and animal prion disorders.
Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport.
Hakim MS, Ding S, Chen S, Yin Y, Su J, van der Woude CJ, Fuhler GM, Peppelenbosch MP, Pan Q, Wang W
Virus research 2018 Jul 15;253:28-37
Virus research 2018 Jul 15;253:28-37
Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders.
Asthana A, Baksi S, Ashok A, Karmakar S, Mammadova N, Kokemuller R, Greenlee MH, Kong Q, Singh N
Scientific reports 2017 Aug 29;7(1):9600
Scientific reports 2017 Aug 29;7(1):9600
Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease.
Tripathi AK, Singh N
Journal of Alzheimer's disease : JAD 2016;51(1):107-21
Journal of Alzheimer's disease : JAD 2016;51(1):107-21
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution.
Gasperini L, Meneghetti E, Legname G, Benetti F
Frontiers in neuroscience 2016;10:437
Frontiers in neuroscience 2016;10:437
A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.
Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N
Antioxidants & redox signaling 2013 Nov 10;19(14):1662-75
Antioxidants & redox signaling 2013 Nov 10;19(14):1662-75
Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains.
Singh A, Qing L, Kong Q, Singh N
Neurobiology of disease 2012 Mar;45(3):930-8
Neurobiology of disease 2012 Mar;45(3):930-8
Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders.
Singh A, Beveridge AJ, Singh N
PloS one 2011 Mar 9;6(3):e16804
PloS one 2011 Mar 9;6(3):e16804
Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis.
Singh A, Mohan ML, Isaac AO, Luo X, Petrak J, Vyoral D, Singh N
PloS one 2009;4(2):e4468
PloS one 2009;4(2):e4468
Abnormal brain iron homeostasis in human and animal prion disorders.
Singh A, Isaac AO, Luo X, Mohan ML, Cohen ML, Chen F, Kong Q, Bartz J, Singh N
PLoS pathogens 2009 Mar;5(3):e1000336
PLoS pathogens 2009 Mar;5(3):e1000336
Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport.
Singh A, Kong Q, Luo X, Petersen RB, Meyerson H, Singh N
PloS one 2009 Jul 1;4(7):e6115
PloS one 2009 Jul 1;4(7):e6115
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Supportive validation
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- Experimental details
- Western Blot of Rabbit Anti-Transferrin primary antibody (GTX21223). Lane 1: Human Transferrin. Lane 2: None. Primary antibody: Transferrin primary antibody at 1:1,000 overnight at 4¢XC. Secondary antibody: Peroxidase rabbit secondary antibody at 1:40,000 for 30 min at RT. Blocking for 30 min at RT. Predicted/Observed size: 76-81 kDa. 76 kDa for Transferrin. Other band(s): Transferrin slice varients and isoforms.