Antibody data
- Antibody Data
- Antigen structure
- References [83]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 17247-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17247-1-AP, RRID:AB_2061878
- Product name
- ATPB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATPB antibody (Cat. #17247-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A small-molecule stabilizer of the calpastatin-calpain-2 complex restores mitochondrial function and mitigates neurodegeneration.
PAMD-Ch17, a Polymeric Analog of Plerixafor, Induces Mitochondrial Dysfunction in T-ALL Cells Independent of CXCR4.
Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.
TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Achilles tendon exhibits distinct transcriptomic changes with increased mitochondrial energy production under lunar gravity.
Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis.
Nitric oxide-primed engineered extracellular vesicles restore bioenergetics in acute kidney injury via mitochondrial transfer.
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
A cold-inducible phospholipid-protein interaction in brown fat mitochondria optimizes thermogenic capacity.
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Microalgae-Derived Extracellular Vesicles Synergize with Herbal Hydrogel for Energy Homeostasis in Osteoarthritis Treatment.
Formoterol, the Most Effective Bronchodilator, Has No Anti-Inflammatory nor Metabolic Modulatory Effects in Severe Asthma Induced by Aspergillus fumigatus.
Organic cation transporter 3 on neuronal mitochondria mediates MPP(+)-induced mitochondrial dysfunction and neurotoxicity in a TIMM22-dependent manner.
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Andrographolide Attenuates Myocardial Ischemia-Reperfusion Injury in Mice by Up-Regulating PPAR-α.
HUWE1-Mediated Degradation of MUTYH Facilitates DNA Damage and Mitochondrial Dysfunction to Promote Acute Kidney Injury.
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.
Proteomimetic polymer blocks mitochondrial damage, rescues Huntington's neurons, and slows onset of neuropathology in vivo.
Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment.
Proteomic Analysis Reveals Major Proteins and Pathways That Mediate the Effect of 17-β-Estradiol in Cell Division and Apoptosis in Breast Cancer MCF7 Cells.
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
Chimeric SFT2D2-TBX19 Promotes Prostate Cancer Progression by Encoding TBX19-202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation.
BCKDK loss impairs mitochondrial Complex I activity and drives alpha-synuclein aggregation in models of Parkinson's disease.
The VDAC1 oligomerization regulated by ATP5B leads to the NLRP3 inflammasome activation in the liver cells under PFOS exposure.
ITFG2, an immune-modulatory protein, targets ATP 5b to maintain mitochondrial function in myocardial infarction.
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice.
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury.
F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α.
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Small noncoding RNA interactome capture reveals pervasive, carbon source-dependent tRNA engagement of yeast glycolytic enzymes.
L-arginine homeostasis governs adult neural stem cell activation by modulating energy metabolism in vivo.
Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy.
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Legionella pneumophila temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation.
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Integrated Analyses Reveal the Multi-Omics and Prognostic Characteristics of ATP5B in Breast Cancer.
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
P2X7 receptor signaling promotes inflammation in renal parenchymal cells suffering from ischemia-reperfusion injury.
Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Mitochondrial F(1) F(O) ATP synthase determines the local proton motive force at cristae rims.
Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase.
In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study.
Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2.
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.
The spatio-temporal organization of mitochondrial F(1)F(O) ATP synthase in cristae depends on its activity mode.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress.
STING directly activates autophagy to tune the innate immune response.
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.
Intervention of mitochondrial activity attenuates cisplatin-induced acute kidney injury.
Mitochondrial stress response triggered by defects in protein synthesis quality control.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
TIM29 is a subunit of the human carrier translocase required for protein transport.
Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.
Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.
Hu D, Sun X, Shang Y, Lundberg K, Adams DJ, Qi X
Science advances 2026 Mar 27;12(13):eaeb1174
Science advances 2026 Mar 27;12(13):eaeb1174
PAMD-Ch17, a Polymeric Analog of Plerixafor, Induces Mitochondrial Dysfunction in T-ALL Cells Independent of CXCR4.
Lam C, Dhir A, Mitro A, Jogdeo CM, Panda S, Kapoor E, Tang S, Rivero VJ, McIntyre EM, Coulter DW, Xiao P, Black AR, Hewitt K, Romanova S, Swenson SA, Oupicky D, Hyde RK
Molecular cancer therapeutics 2026 Mar 27;
Molecular cancer therapeutics 2026 Mar 27;
Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.
Senoo N, Sheridan MS, Wohlfarter Y, Primrose MT, Tampakakis E, Keller MA, Claypool SM
iScience 2026 Mar 20;29(3):115111
iScience 2026 Mar 20;29(3):115111
TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
Barone C, Wang R, Cooke S, Ng HP, Ferreira RS, Miranda HC, Qi X
Acta neuropathologica 2026 Mar 16;151(1)
Acta neuropathologica 2026 Mar 16;151(1)
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Deng Y, Yang W, Yang J, Ji L, Xie M, Tang K, He Q, Hu G, Shangguan W, Jiang C, Li T
Redox biology 2026 Jun;93:104163
Redox biology 2026 Jun;93:104163
Achilles tendon exhibits distinct transcriptomic changes with increased mitochondrial energy production under lunar gravity.
Kasai T, Tsubaki T, Matsumoto T, Iwanaga Y, Terashima A, Omata Y, Tanaka S, Saito T
NPJ microgravity 2026 Apr 10;
NPJ microgravity 2026 Apr 10;
Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis.
Wang XL, He JH, Xie P, Wu Y, Dong LY, An W
Cellular and molecular gastroenterology and hepatology 2025;19(3):101436
Cellular and molecular gastroenterology and hepatology 2025;19(3):101436
Nitric oxide-primed engineered extracellular vesicles restore bioenergetics in acute kidney injury via mitochondrial transfer.
Peng F, Chen X, Wu L, He J, Li Z, Hong Q, Zhao Q, Qian M, Wang X, Shen W, Qi T, Huang Y, Cai G, Zhang C, Chen X
Theranostics 2025;15(11):5499-5517
Theranostics 2025;15(11):5499-5517
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
Liao SC, Kano K, Phanse S, Nguyen M, Margolis E, Fu Y, X Meng J, Moutaoufik MT, Chatterton Z, Saccon T, Broderick K, Aoki H, Simms J, Suteja FX, Sei Y, Huang EJ, McAvoy K, Manfredi G, Halliday G, Babu M, Nakamura K
Science advances 2025 Nov 14;11(46):eadu0726
Science advances 2025 Nov 14;11(46):eadu0726
A cold-inducible phospholipid-protein interaction in brown fat mitochondria optimizes thermogenic capacity.
Shimanaka Y, Tol MJ, Rocha-Roa C, Jellinek MJ, Cui L, Bender A, Bedard AH, Milner MG, Melillo B, Shoucri BM, Wong A, Williams KJ, Stiles L, Shum M, Weston TA, Cohn W, Whitelegge JP, Budin I, Bertholet AM, Cravatt BF, Young SG, Houten SM, Argmann C, Ford DA, Liesa M, Shirihai OS, Vanni S, Tontonoz P
bioRxiv : the preprint server for biology 2025 May 18;
bioRxiv : the preprint server for biology 2025 May 18;
Leucine 7 is a key residue for mutant huntingtin-induced mitochondrial pathology and neurotoxicity in Huntington's disease.
Zhang S, Wang S, Yang Z, Li Y, Li J, Chen X, Yao H, Zheng Z, Guo X
The Journal of biological chemistry 2025 Mar;301(3):108297
The Journal of biological chemistry 2025 Mar;301(3):108297
Microalgae-Derived Extracellular Vesicles Synergize with Herbal Hydrogel for Energy Homeostasis in Osteoarthritis Treatment.
Liang F, Zheng Y, Zhao C, Li L, Hu Y, Wang C, Wang R, Feng T, Liu X, Cui J, Zhong D, Zhou M
ACS nano 2025 Mar 4;19(8):8040-8057
ACS nano 2025 Mar 4;19(8):8040-8057
Formoterol, the Most Effective Bronchodilator, Has No Anti-Inflammatory nor Metabolic Modulatory Effects in Severe Asthma Induced by Aspergillus fumigatus.
Gan PXL, Linke KM, Liao W, Wong WSF
ACS pharmacology & translational science 2025 Jun 13;8(6):1556-1566
ACS pharmacology & translational science 2025 Jun 13;8(6):1556-1566
Organic cation transporter 3 on neuronal mitochondria mediates MPP(+)-induced mitochondrial dysfunction and neurotoxicity in a TIMM22-dependent manner.
Guan A, Han S, Liang S, Shen W, Guo M, Cui M
BMC biology 2025 Jul 15;23(1):214
BMC biology 2025 Jul 15;23(1):214
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Wang P, Ouyang J, Zhou K, Hu D, Zhang S, Zhang A, Yang Y
Biomedical journal 2025 Feb;48(1):100730
Biomedical journal 2025 Feb;48(1):100730
Andrographolide Attenuates Myocardial Ischemia-Reperfusion Injury in Mice by Up-Regulating PPAR-α.
Zhang S, Ye Y, Li Q, Zhao J, Song R, Huang C, Lu X, Huang C, Yin L, You Q
Inflammation 2025 Aug;48(4):2341-2354
Inflammation 2025 Aug;48(4):2341-2354
HUWE1-Mediated Degradation of MUTYH Facilitates DNA Damage and Mitochondrial Dysfunction to Promote Acute Kidney Injury.
Yang Y, Wang P, Zhou K, Zhang W, Liu S, Ouyang J, Bai M, Ding G, Huang S, Jia Z, Zhang A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2412250
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2412250
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Li T, Bao Y, Xia Y, Meng H, Zhou C, Huang L, Wang X, Lai EY, Jiang P, Mao J
International journal of biological sciences 2024;20(3):937-952
International journal of biological sciences 2024;20(3):937-952
Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.
Wen C, Jiang Y, Chen W, Xu Y, Chen G, Zhou Q, Liu Q, Jiang H, Liu Y, Cao X, Yao Y, Zhang R, Qiu Z, Liu S
Experimental and therapeutic medicine 2024 Sep;28(3):349
Experimental and therapeutic medicine 2024 Sep;28(3):349
RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.
Feng N, Zhang R, Wen X, Wang W, Zhang N, Zheng J, Zhang L, Liu N
Communications biology 2024 Oct 16;7(1):1333
Communications biology 2024 Oct 16;7(1):1333
Proteomimetic polymer blocks mitochondrial damage, rescues Huntington's neurons, and slows onset of neuropathology in vivo.
Choi W, Fattah M, Shang Y, Thompson MP, Carrow KP, Hu D, Liu Z, Avram MJ, Bailey K, Berger O, Qi X, Gianneschi NC
Science advances 2024 Nov;10(44):eado8307
Science advances 2024 Nov;10(44):eado8307
Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment.
Sun F, Wang H, Wu J, Quraishi IH, Zhang Y, Pedram M, Gao B, Jonas EA, Nguyen V, Wu S, Mabrouk OS, Jafar-Nejad P, Kaczmarek LK
Biomolecules 2024 Nov 2;14(11)
Biomolecules 2024 Nov 2;14(11)
Proteomic Analysis Reveals Major Proteins and Pathways That Mediate the Effect of 17-β-Estradiol in Cell Division and Apoptosis in Breast Cancer MCF7 Cells.
Zhou Z, Sicairos B, Zhou J, Du Y
Journal of proteome research 2024 Nov 1;23(11):4835-4848
Journal of proteome research 2024 Nov 1;23(11):4835-4848
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Wang M, Wang J, Wang L, Feng X, Qian Y, Ye C, Wang C
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
Chimeric SFT2D2-TBX19 Promotes Prostate Cancer Progression by Encoding TBX19-202 Protein and Stabilizing Mitochondrial ATP Synthase through ATP5F1A Phosphorylation.
Hu C, Zheng Z, Pang S, Zhu Y, Jie J, Lai Z, Zeng X, Xiao Y, Chen Z, Zhao J, Du Y, Li F, Wang Q, Tan W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408426
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408426
BCKDK loss impairs mitochondrial Complex I activity and drives alpha-synuclein aggregation in models of Parkinson's disease.
Jishi A, Hu D, Shang Y, Wang R, Gunzler SA, Qi X
Acta neuropathologica communications 2024 Dec 21;12(1):198
Acta neuropathologica communications 2024 Dec 21;12(1):198
The VDAC1 oligomerization regulated by ATP5B leads to the NLRP3 inflammasome activation in the liver cells under PFOS exposure.
Ma Y, Yang W, Liang P, Feng R, Qiu T, Zhang J, Sun X, Li Q, Yang G, Yao X
Ecotoxicology and environmental safety 2024 Aug;281:116647
Ecotoxicology and environmental safety 2024 Aug;281:116647
ITFG2, an immune-modulatory protein, targets ATP 5b to maintain mitochondrial function in myocardial infarction.
Bi FF, Cao M, Pan QM, Jing ZH, Lv LF, Liu F, Tian H, Yu T, Li TY, Li XL, Liang HH, Shan HL, Zhou YH
Biochemical pharmacology 2024 Aug;226:116338
Biochemical pharmacology 2024 Aug;226:116338
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Cai F, Li D, Zhou K, Zhang W, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155407
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice.
Gorski K, Jackson CB, Nyman TA, Rezov V, Battersby BJ, Lehesjoki AE
Frontiers in molecular neuroscience 2023;16:1175851
Frontiers in molecular neuroscience 2023;16:1175851
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury.
Hong X, Nie H, Deng J, Liang S, Chen L, Li J, Gong S, Wang G, Zuo W, Hou F, Zhang F
Theranostics 2023;13(4):1311-1324
Theranostics 2023;13(4):1311-1324
F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α.
Guo L, Gu Z
Frontiers in oncology 2023;13:1207603
Frontiers in oncology 2023;13:1207603
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Fu J, Liu G, Zhang X, Lei X, Liu Q, Qian K, Tong Q, Qin W, Li Z, Cao Z, Zhang J, Liu C, Wang Z, Liu Z, Liang XM, Yamamoto H, Xu X
Cancer gene therapy 2023 May;30(5):738-751
Cancer gene therapy 2023 May;30(5):738-751
Small noncoding RNA interactome capture reveals pervasive, carbon source-dependent tRNA engagement of yeast glycolytic enzymes.
Asencio C, Schwarzl T, Sahadevan S, Hentze MW
RNA (New York, N.Y.) 2023 Mar;29(3):330-345
RNA (New York, N.Y.) 2023 Mar;29(3):330-345
L-arginine homeostasis governs adult neural stem cell activation by modulating energy metabolism in vivo.
Xu M, Guo Y, Wang M, Luo X, Shen X, Li Z, Wang L, Guo W
The EMBO journal 2023 Mar 15;42(6):e112647
The EMBO journal 2023 Mar 15;42(6):e112647
Ligand-free mitochondria-localized mutant AR-induced cytotoxicity in spinal bulbar muscular atrophy.
Feng X, Cheng XT, Zheng P, Li Y, Hakim J, Zhang SQ, Anderson SM, Linask K, Prestil R, Zou J, Sheng ZH, Blackstone C
Brain : a journal of neurology 2023 Jan 5;146(1):278-294
Brain : a journal of neurology 2023 Jan 5;146(1):278-294
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.
Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D, Birth Defects Research Laboratory, Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X
Neuron 2023 Dec 20;111(24):3988-4005.e11
Neuron 2023 Dec 20;111(24):3988-4005.e11
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Yu X, Liu X, Mi X, Luo X, Lian Z, Tang J, Wang G
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice.
Xin J, Zhu B, Wang H, Zhang Y, Sun N, Cao X, Zheng L, Zhou Y, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Li F, Xia Y, Xu P, Ni X
Journal of hazardous materials 2023 Aug 15;456:131595
Journal of hazardous materials 2023 Aug 15;456:131595
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, Deng C, Feng J, Du S, Liu W, Geng G, Ma K, Cheng H, Liu Q, Luo Q, Zhang J, Du Z, Cao L, Wang H, Liu Y, Lin J, Chen G, Liu L, Lam SM, Shui G, Zhu Y, Chen Q
EMBO reports 2023 Apr 5;24(4):e54731
EMBO reports 2023 Apr 5;24(4):e54731
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
Song J, Sheng J, Lei J, Gan W, Yang Y
Oxidative medicine and cellular longevity 2022;2022:2223957
Oxidative medicine and cellular longevity 2022;2022:2223957
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Jia Z, Meng F, Chen H, Zhu G, Li X, He Y, Zhang L, He X, Zhan H, Chen M, Ji Y, Wang M, Guan MX
Nucleic acids research 2022 Sep 9;50(16):9368-9381
Nucleic acids research 2022 Sep 9;50(16):9368-9381
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
Shang Y, Sun X, Chen X, Wang Q, Wang EJ, Miller E, Xu R, Pieper AA, Qi X
Acta neuropathologica 2022 Nov;144(5):911-938
Acta neuropathologica 2022 Nov;144(5):911-938
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Gao Z, Zhang C, Peng F, Chen Q, Zhao Y, Chen L, Wang X, Chen X
Stem cell research & therapy 2022 May 7;13(1):191
Stem cell research & therapy 2022 May 7;13(1):191
Legionella pneumophila temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation.
Fu J, Li P, Guan H, Huang D, Song L, Ouyang S, Luo ZQ
mLife 2022 Mar;1(1):51-65
mLife 2022 Mar;1(1):51-65
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, Lundberg K, Wang Q, Adams DJ, Xu R, Qi X
Nature communications 2022 Mar 2;13(1):1121
Nature communications 2022 Mar 2;13(1):1121
Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
Fu J, Zhou M, Gritsenko MA, Nakayasu ES, Song L, Luo ZQ
eLife 2022 Jan 27;11
eLife 2022 Jan 27;11
Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.
Suzuki C, Fujiwara T, Shima H, Ono K, Saito K, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Igarashi K, Harigae H
Molecular and cellular biology 2022 Dec 15;42(12):e0014322
Molecular and cellular biology 2022 Dec 15;42(12):e0014322
TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549
Frontiers in cell and developmental biology 2021;9:726549
Integrated Analyses Reveal the Multi-Omics and Prognostic Characteristics of ATP5B in Breast Cancer.
Liu M, Xu Y, Zhou Y, Lang R, Shi Z, Zhao J, Meng Y, Bao L
Frontiers in genetics 2021;12:652474
Frontiers in genetics 2021;12:652474
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X
Nature communications 2021 Sep 6;12(1):5305
Nature communications 2021 Sep 6;12(1):5305
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Zhang W, Zhao W, Li Q, Zhao D, Qu J, Yuan Z, Cheng Z, Zhu X, Zhuang X, Zhang Z
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Sakai M, Takahashi N, Ikeda H, Furutani Y, Higuchi S, Suzuki T, Dohmae N, Kobayashi S, Harada H, Kojima S, Matsuura T, Hattori A, Kakeya H
Bioorganic & medicinal chemistry 2021 Sep 15;46:116375
Bioorganic & medicinal chemistry 2021 Sep 15;46:116375
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
Jin X, Zhang J, Yi Q, Meng F, Yu J, Ji Y, Mo JQ, Tong Y, Jiang P, Guan MX
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 17247-1-AP(ATPB antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-ATPB (IP:17247-1-AP, 3ug; Detection:17247-1-AP 1:500) with mouse heart tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ATPB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATPB. This antibody recognizes human,mouse,rat antigen. The ATPB antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17247-1-AP(ATPB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue