Antibody data
- Antibody Data
- Antigen structure
- References [31]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 17247-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17247-1-AP, RRID:AB_2061878
- Product name
- ATPB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATPB antibody (Cat. #17247-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.
Integrated Analyses Reveal the Multi-Omics and Prognostic Characteristics of ATP5B in Breast Cancer.
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
P2X7 receptor signaling promotes inflammation in renal parenchymal cells suffering from ischemia-reperfusion injury.
Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Mitochondrial F1 FO ATP synthase determines the local proton motive force at cristae rims.
Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase.
Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2.
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress.
STING directly activates autophagy to tune the innate immune response.
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.
Intervention of mitochondrial activity attenuates cisplatin-induced acute kidney injury.
Mitochondrial stress response triggered by defects in protein synthesis quality control.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
TIM29 is a subunit of the human carrier translocase required for protein transport.
Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.
Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.
Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549
Frontiers in cell and developmental biology 2021;9:726549
Integrated Analyses Reveal the Multi-Omics and Prognostic Characteristics of ATP5B in Breast Cancer.
Liu M, Xu Y, Zhou Y, Lang R, Shi Z, Zhao J, Meng Y, Bao L
Frontiers in genetics 2021;12:652474
Frontiers in genetics 2021;12:652474
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X
Nature communications 2021 Sep 6;12(1):5305
Nature communications 2021 Sep 6;12(1):5305
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Zhang W, Zhao W, Li Q, Zhao D, Qu J, Yuan Z, Cheng Z, Zhu X, Zhuang X, Zhang Z
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Sakai M, Takahashi N, Ikeda H, Furutani Y, Higuchi S, Suzuki T, Dohmae N, Kobayashi S, Harada H, Kojima S, Matsuura T, Hattori A, Kakeya H
Bioorganic & medicinal chemistry 2021 Sep 15;46:116375
Bioorganic & medicinal chemistry 2021 Sep 15;46:116375
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
Jin X, Zhang J, Yi Q, Meng F, Yu J, Ji Y, Mo JQ, Tong Y, Jiang P, Guan MX
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L, Wu JY
EMBO reports 2021 Jul 5;22(7):e52006
EMBO reports 2021 Jul 5;22(7):e52006
P2X7 receptor signaling promotes inflammation in renal parenchymal cells suffering from ischemia-reperfusion injury.
Qian Y, Qian C, Xie K, Fan Q, Yan Y, Lu R, Wang L, Zhang M, Wang Q, Mou S, Dai H, Ni Z, Pang H, Gu L
Cell death & disease 2021 Jan 27;12(1):132
Cell death & disease 2021 Jan 27;12(1):132
Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase.
Weissert V, Rieger B, Morris S, Arroum T, Psathaki OE, Zobel T, Perkins G, Busch KB
Biochimica et biophysica acta. Bioenergetics 2021 Jan 1;1862(1):148322
Biochimica et biophysica acta. Bioenergetics 2021 Jan 1;1862(1):148322
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
Mitochondrial F1 FO ATP synthase determines the local proton motive force at cristae rims.
Rieger B, Arroum T, Borowski MT, Villalta J, Busch KB
EMBO reports 2021 Dec 6;22(12):e52727
EMBO reports 2021 Dec 6;22(12):e52727
Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase.
Reisman BJ, Guo H, Ramsey HE, Wright MT, Reinfeld BI, Ferrell PB, Sulikowski GA, Rathmell WK, Savona MR, Plate L, Rubinstein JL, Bachmann BO
Nature chemical biology 2021 Dec 2;
Nature chemical biology 2021 Dec 2;
Shen Shuai II Recipe Attenuates Apoptosis in 5/6 Renal Ablation/Infarction Rats by Inhibiting p53 and the Mitochondrial Pathway of Apoptosis.
Wang M, Yang J, Wang C
Oxidative medicine and cellular longevity 2020;2020:7083575
Oxidative medicine and cellular longevity 2020;2020:7083575
Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2.
Yang Y, Liu S, Gao H, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
Free radical biology & medicine 2020 May 20;152:821-837
Free radical biology & medicine 2020 May 20;152:821-837
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.
Yang L, Liu Q, Zhang X, Liu X, Zhou B, Chen J, Huang D, Li J, Li H, Chen F, Liu J, Xing Y, Chen X, Su S, Song E
Nature 2020 Jul;583(7814):133-138
Nature 2020 Jul;583(7814):133-138
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress.
Zhang M, Wu J, Sun R, Tao X, Wang X, Kang Q, Wang H, Zhang L, Liu P, Zhang J, Xia Y, Zhao Y, Yang Y, Xiong Y, Guan KL, Zou Y, Ye D
PloS one 2019;14(2):e0211796
PloS one 2019;14(2):e0211796
STING directly activates autophagy to tune the innate immune response.
Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, Sehgal SA, Wang X, Wang J, Shang Y, Jiang Z, Liu L, Chen Q
Cell death and differentiation 2019 Sep;26(9):1735-1749
Cell death and differentiation 2019 Sep;26(9):1735-1749
Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis.
Wang M, Yang L, Yang J, Zhou Y, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109316
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.
Wu H, Wang Y, Li W, Chen H, Du L, Liu D, Wang X, Xu T, Liu L, Chen Q
Autophagy 2019 Nov;15(11):1882-1898
Autophagy 2019 Nov;15(11):1882-1898
Intervention of mitochondrial activity attenuates cisplatin-induced acute kidney injury.
Yang Y, Fu Y, Wang P, Liu S, Sha Y, Zhang Y, Zhang A, Jia Z, Ding G, Huang S
International urology and nephrology 2019 Jul;51(7):1207-1218
International urology and nephrology 2019 Jul;51(7):1207-1218
Mitochondrial stress response triggered by defects in protein synthesis quality control.
Richter U, Ng KY, Suomi F, Marttinen P, Turunen T, Jackson C, Suomalainen A, Vihinen H, Jokitalo E, Nyman TA, Isokallio MA, Stewart JB, Mancini C, Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ
Life science alliance 2019 Feb;2(1)
Life science alliance 2019 Feb;2(1)
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Zhang W, Sha Y, Wei K, Wu C, Ding D, Yang Y, Zhu C, Zhang Y, Ding G, Zhang A, Jia Z, Huang S
Oncotarget 2018 May 11;9(36):24199-24208
Oncotarget 2018 May 11;9(36):24199-24208
PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver.
Xiao Y, Zhou Y, Lu Y, Zhou K, Cai W
Cell death & disease 2018 Feb 7;9(2):160
Cell death & disease 2018 Feb 7;9(2):160
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Di Nottia M, Masciullo M, Verrigni D, Petrillo S, Modoni A, Rizzo V, Di Giuda D, Rizza T, Niceta M, Torraco A, Bianchi M, Santoro M, Bentivoglio AR, Bertini E, Piemonte F, Carrozzo R, Silvestri G
Clinical genetics 2017 Jul;92(1):18-25
Clinical genetics 2017 Jul;92(1):18-25
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Li P, Zhang D, Shen L, Dong K, Wu M, Ou Z, Shi D
Scientific reports 2016 Mar 9;6:22831
Scientific reports 2016 Mar 9;6:22831
TIM29 is a subunit of the human carrier translocase required for protein transport.
Callegari S, Richter F, Chojnacka K, Jans DC, Lorenzi I, Pacheu-Grau D, Jakobs S, Lenz C, Urlaub H, Dudek J, Chacinska A, Rehling P
FEBS letters 2016 Dec;590(23):4147-4158
FEBS letters 2016 Dec;590(23):4147-4158
Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.
Richter U, Lahtinen T, Marttinen P, Suomi F, Battersby BJ
The Journal of cell biology 2015 Oct 26;211(2):373-89
The Journal of cell biology 2015 Oct 26;211(2):373-89
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ
Genetics 2015 May;200(1):221-35
Genetics 2015 May;200(1):221-35
Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.
Hall JA, Kusuma BR, Brandt GE, Blagg BS
ACS chemical biology 2014 Apr 18;9(4):976-85
ACS chemical biology 2014 Apr 18;9(4):976-85
Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.
Preuss B, Berg C, Dengjel J, Stevanovic S, Klein R
Liver international : official journal of the International Association for the Study of the Liver 2012 Feb;32(2):249-57
Liver international : official journal of the International Association for the Study of the Liver 2012 Feb;32(2):249-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 17247-1-AP(ATPB antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ATPB (IP:17247-1-AP, 3ug; Detection:17247-1-AP 1:500) with mouse heart tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATPB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATPB. This antibody recognizes human,mouse,rat antigen. The ATPB antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17247-1-AP(ATPB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue