ABIN1673059

antibody from antibodies-online

Targeting: SPARC BM-40, ON, ONT

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673059

Provider

antibodies-online

Product name

anti-Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human SPARC.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Genes that mediate breast cancer metastasis to lung.

Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massagué J
Nature 2005 Jul 28;436(7050):518-24

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Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.

Gilmour DT, Lyon GJ, Carlton MB, Sanes JR, Cunningham JM, Anderson JR, Hogan BL, Evans MJ, Colledge WH
The EMBO journal 1998 Apr 1;17(7):1860-70

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SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function.

Goldblum SE, Ding X, Funk SE, Sage EH
Proceedings of the National Academy of Sciences of the United States of America 1994 Apr 12;91(8):3448-52