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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Immunoelectron microscopy [1]
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- Product number
- AB0043-200 - Provider product page
- Provider
- SICGEN
- Proper citation
- SICGEN Cat#AB0043-200, RRID:AB_2333119
- Product name
- Anti-Cathepsin D
- Antibody type
- Polyclonal
- Description
- Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 600 µg
- Concentration
- 3 mg/ml
- Storage
- Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.
Pelkonen L, Sato K, Reinisalo M, Kidron H, Tachikawa M, Watanabe M, Uchida Y, Urtti A, Terasaki T
Molecular pharmaceutics 2017 Mar 6;14(3):605-613
Molecular pharmaceutics 2017 Mar 6;14(3):605-613
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Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- Cell lysate at 100 µg and 30 µg per lane (transfected)
- Sample type
- Anti-CTSD Ab (AB0043) at 1/500 dilution; endogenous CTSD and transfected 293FT cells
- Primary Ab dilution
- 1/500
- Conjugate
- Unconjugated
- Secondary Ab
- Secondary Ab
- Secondary Ab dilution
- 1/10,000
Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- paraformaldehyde-fixed paraffin-embedded tissue
- Sample type
- mouse lung
- Primary Ab dilution
- 1/200
- Conjugate
- Unconjugated
Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- IEM
- Sample type
- Melanocytes
