DPABH-16496

antibody from Creative Diagnostics

Targeting: ZDHHC17 HIP14, HYPH, KIAA0946

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-16496

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-16496, RRID:AB_2525842

Product name

Rabbit Anti-Human ZDHHC17 Polyclonal antibody

Antibody type

Polyclonal

Description

Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL