MA5-11751

antibody from Invitrogen Antibodies

Targeting: F13A1 F13A

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-11751

Provider

Invitrogen Antibodies

Product name

Factor XIII A Monoclonal Antibody (AC-1A1)

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

MA5-11751 targets Factor XIII A in IHC (P) and WB applications and shows reactivity with Human samples. The MA5-11751 immunogen is recombinant protein corresponding to A-subunit of coagulation Factor XIII.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

AC-1A1

Vial size

500 µL

Concentration

0.1 mg/mL

Storage

4° C

References

Submitted references

Transcriptome of microglia reveals a species-specific expression profile in bovines with conserved and new signature genes.

Tavares-Gomes L, Monney C, Neuhaus G, Francisco D, Solis D, Summerfield A, Erny D, Jagannathan V, Oevermann A
Glia 2021 Aug;69(8):1932-1949

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Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.

Abaeva AA, Canault M, Kotova YN, Obydennyy SI, Yakimenko AO, Podoplelova NA, Kolyadko VN, Chambost H, Mazurov AV, Ataullakhanov FI, Nurden AT, Alessi MC, Panteleev MA
The Journal of biological chemistry 2013 Oct 11;288(41):29621-32

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Malignant dermatofibroma: clinicopathological, immunohistochemical, and molecular analysis of seven cases.

Mentzel T, Wiesner T, Cerroni L, Hantschke M, Kutzner H, Rütten A, Häberle M, Bisceglia M, Chibon F, Coindre JM
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Feb;26(2):256-67

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Plaque-like CD34-positive dermal fibroma ("medallion-like dermal dendrocyte hamartoma"): clinicopathologic, immunohistochemical, and molecular analysis of 5 cases emphasizing its distinction from superficial, plaque-like dermatofibrosarcoma protuberans.

Kutzner H, Mentzel T, Palmedo G, Hantschke M, Rütten A, Paredes BE, Schärer L, Guillen CS, Requena L
The American journal of surgical pathology 2010 Feb;34(2):190-201

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Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm.

Mentzel T, Kutzner H
The American Journal of dermatopathology 2009 Feb;31(1):44-9

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Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent.

Miserus RJ, Herías MV, Prinzen L, Lobbes MB, Van Suylen RJ, Dirksen A, Hackeng TM, Heemskerk JW, van Engelshoven JM, Daemen MJ, van Zandvoort MA, Heeneman S, Kooi ME
JACC. Cardiovascular imaging 2009 Aug;2(8):987-96

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Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA.

Huebner JL, Johnson KA, Kraus VB, Terkeltaub RA
Osteoarthritis and cartilage 2009 Aug;17(8):1056-64

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Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages.

Zaba LC, Fuentes-Duculan J, Steinman RM, Krueger JG, Lowes MA
The Journal of clinical investigation 2007 Sep;117(9):2517-25

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Expression and localization of plasma transglutaminase factor XIIIA in bone.

Nakano Y, Al-Jallad HF, Mousa A, Kaartinen MT
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 Jul;55(7):675-85

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The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha.

Lohwasser C, Neureiter D, Weigle B, Kirchner T, Schuppan D
The Journal of investigative dermatology 2006 Feb;126(2):291-9

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Incidental calcifying fibrous tumor of the stomach presenting as a polyp.

Elpek GO, Küpesiz GY, Ogüs M
Pathology international 2006 Apr;56(4):227-31

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Mammalian transglutaminases: a family portrait.

Mehta K
Progress in experimental tumor research 2005;38:1-18

Western blot

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot of Factor XIII A using Factor XIII A Monoclonal Antibody (Product # MA5-11751) on GST Factor 8 Recombinant Protein.

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded human placenta stained with Factor XIIIa antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of fibroblasts and macrophages

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

3 FIGURE (a,b) P2RY12 expression in-situ: IHC for P2RY12 in cow brains shows that P2RY12-expressing microglia are detected in (a) paraffin-embedded healthy cow brain and in (b) areas of inflammation in cow brains affected by neurolisteriosis; insets show higher magnifications of (a) resting and (b) reactive microglia. (c,d) F13A1 expression in-situ: IHC for F13A1 in (c) paraffin-embedded healthy cow brain shows absence of F13A1 expressing cells in the neuroparenchyma; in contrast, F13A1 expressing infiltrating MDM are present in (d) microabscess areas of brains with neurolisteriosis; insets show higher magnifications of (c) healthy neuroparenchyma and (d) infiltrating MDM. (e) IF of healthy brain tissue shows that all IBA1 positive cells (blue) express P2RY12 (red). (f) In areas of inflammation P2RY12 (red) shows no overlap with F13A1 (blue)