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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [264]
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- Product number
- 66305-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66305-1-Ig, RRID:AB_2810300
- Product name
- Vinculin antibody
- Antibody type
- Monoclonal
- Description
- Vinculin antibody (Cat. #66305-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B5A7
- Vial size
- 150ul
Submitted references Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer.
Global stabilization of the transcriptome in mitotic cells.
Mitochondrial control of glycerolipid synthesis by a PEP shuttle.
p53 and fatty acids collaborate to trigger ferroptosis via the FBXO2-FABP5 axis in colorectal cancer.
VAMP8 function reveals tight linkage between endocytic recycling and endocytosis.
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Knockdown of Ddx3x in mPFC induces autistic-like phenotype in mice via altered synaptic plasticity.
DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling-Mediated Anti-tumor Immunity.
Pro-Inflammatory Activation Promotes Atherogenic Endothelial Phenotype in Male and Female Human Umbilical Endothelial Vein Cells (HUVECs).
Structurally-defined non-cationic docosahexaenoic acid based siRNA-micelles for safe and effective combinatorial glioblastoma therapy.
Mitochondrial control of glycerolipid synthesis by a PEP shuttle.
Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer.
Unraveling the antidepressant mechanisms of JiaWeiSiNiSan: Insights from network pharmacology and experimental validation.
Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma.
Transcriptomics-guided high-throughput drug screening identifies potent therapies for P53 pathway altered DIPG/DMG.
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Environmentally relevant lanthanum chloride exposure induces hepatic steatosis in zebrafish larvae via PPARα-dependent ApoB suppression.
Cis and Trans Regulatory Mechanisms of ecDNA Segregation.
FBXO22 targets ubiquitination and degradation of c-Cbl in leukemia.
Bioadhesive Scaffold for Dual Delivery of Methotrexate-Loaded Liposomes and Chondrogenic miRNA in Advanced Rheumatoid Arthritis Therapy.
Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy.
Versatile CRISPR-Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System.
Treatment of Huntington's disease with a pan-HTT-targeting CRISPR nuclease.
Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress.
Extracellular vesicles-miR-205-5p inhibits lymphatic metastasis in pancreatic cancer through diffusely downregulating VEGFA.
Network pharmacology combined with molecular docking and experimental validation of the mechanism of action of columbianetin acetate in the treatment of ovarian cancer.
Exploring the Functional Role of Programmed Death-Ligand 1 (PD-L1) in the Castration-Resistant Prostate Cancer Using Transcriptomic Sequencing Analysis.
Genome-wide mapping of RNA-protein associations through sequencing.
Erucic acid impairs male fertility by suppressing retinoic acid synthesis in sertoli cells.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
The individual isoforms of ORMDL, the regulatory subunit of serine palmitoyltransferase, have distinctive sensitivities to ceramide.
Androgen regulates seasonal changes in triglyceride synthesis through the AR-SREBP1-FASN axis in the scented glands of muskrats (Ondatra zibethicus).
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
The PDGFBB-PDGFRβ Pathway and Laminins in Pericytes Are Involved in the Temporal Change of AQP4 Polarity during Temporal Lobe Epilepsy Pathogenesis.
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.
Differential cell survival outcomes in response to diverse amino acid stress.
The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity.
C1orf50 Accelerates Epithelial-Mesenchymal Transition and the Cell Cycle of Hepatocellular Carcinoma.
Dihydromyricetin exerts dual anti-acne actions by suppressing propionibacterium acnes proliferation and host inflammatory responses via TLR2/NF-κB/MAPK pathway inhibition.
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
Epigenetic regulation of ACSL4 via H2A monoubiquitylation connects lipid metabolism to BAP1-mediated ferroptosis.
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment.
Dihydrotanshinone I potentiates the anti-tumor activity of cisplatin by activating ROS-mediated ER stress through targeting HSPD1 in lung cancer cells.
STIM1/2 maintain signaling competence at ER-PM contact sites during neutrophil spreading.
Modulation of Filopodial Myosin Function.
Indole-3-lactic acid derived from tryptophan metabolism promotes trophoblast migration and invasion by activating the AhR/VCAN pathway.
Vascular grafts with a mimetic microenvironment extracted from extracellular matrix of adipocytes can promote endothelialization in vivo.
Inherited deficiency of DIAPH1 identifies a DNA double strand break repair pathway regulated by γ-actin.
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Exosomal miR-184 facilitates bladder cancer progression by targeting AKR1C3 and inducing immune escape via IRF2-CXCL10 axis.
Loss of MNX1 Sensitizes Tumors to Cytotoxic T Cells by Degradation of PD-L1 mRNA.
Intratumoral Collagen Deposition Supports Angiogenesis Suggesting Anti-angiogenic Therapy in Armored and Cold Tumors.
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
The individual isoforms of ORMDL, the regulatory subunit of serine palmitoyltransferase, have distinctive sensitivities to ceramide.
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo.
Noscapine derivative 428 suppresses ferroptosis through targeting GPX4.
Polygonati kingianum polysaccharide alleviates dextran sulfate sodium-induced colitis by modulating gut microbiota and metabolic homeostasis.
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2.
Constitutive HIF-1α Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation.
Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.
Hexahydrocurcumin suppresses hepatocellular carcinoma by regulating TRIM23/MBNL1 pathway.
E3 ligase TRIM22 promotes melanoma proliferation by regulating cell cycle progression through K63-linked ubiquitination of p21.
Disruption of Ferroptosis Inhibition and Immune Evasion with Tumor-Activatable Prodrug for Boosted Photodynamic/Chemotherapy Eradication of Drug-Resistant Tumors.
Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation.
Decoding the general role of tRNA queuosine modification in eukaryotes.
Tubeimoside-I, an inhibitor of HSPD1, enhances cytotoxicity of oxaliplatin by activating ER stress and MAPK signaling pathways in colorectal cancer.
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism.
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Metabolic dysfunction in mice with adipocyte-specific ablation of the adenosine A2A receptor.
Inhibition of Endoplasmic Reticulum Stress Cooperates with SLC7A11 to Promote Disulfidptosis and Suppress Tumor Growth upon Glucose Limitation.
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers.
SAMD9L inhibits flavivirus translation independently of its capacity to trigger innate immune response.
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.
Genetic characterization and screening of congenital adrenal hyperplasia by long-read sequencing in a cohort of 21,239 newborns.
Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.
Treatment of Huntington's disease with a pan-HTT-targeting CRISPR nuclease.
TCF19 promotes gastric cancer progression through MCM6.
Single-cell, spatial and bulk transcriptome data analysis revealed LINC00467-mediated Sertoli cell ferroptosis is a potential therapeutic target and biomarker for azoospermia.
Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention.
Reduction in vinculin levels with Rb1 loss is responsible for altered differentiation in preosteoblasts.
Mitoxantrone-Encapsulated ZIF-8 Enhances Chemo-Immunotherapy via Amplified Immunogenic Cell Death.
HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis.
Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer.
FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release.
Usutu virus NS4A induces autophagy and is targeted by the selective autophagy receptor p62/SQSTM1 for degradation.
Transcription factor MEF2D regulates aberrant expression of ACSL3 and enhances sorafenib resistance by inhibiting ferroptosis in HCC.
SENP3 sensitizes macrophages to ferroptosis via de-SUMOylation of FSP1.
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains.
Granulosa Cell-Layer Stiffening Prevents Escape of Mural Granulosa Cells from the Post-Ovulatory Follicle.
Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention.
Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation and Pyroptosis.
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
Chiral Hydrogel Nerve Conduit Boosts Peripheral Nerve Regeneration via Regulation of Schwann Cell Reprogramming.
Targeting NQO1 induces ferroptosis and triggers anti-tumor immunity in immunotherapy-resistant KEAP1-deficient cancers.
PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina3.
METTL3 facilitates kidney injury through promoting IRF4-mediated plasma cell infiltration via an m6A-dependent manner in systemic lupus erythematosus.
Multi-protomics analysis identified host cellular pathways perturbed by tick-borne encephalitis virus infection.
An interaction network of inner centriole proteins organised by POC1A-POC1B heterodimer crosslinks ensures centriolar integrity.
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.
A Zinc Oxide Nanowire-Modified Mineralized Collagen Scaffold Promotes Infectious Bone Regeneration.
Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Label-free cell phenotypic profiling of histamine H4R receptor and discovery of non-competitive H4R antagonist from natural products.
Heparin-Functionalized Bioactive Glass to Harvest Endogenous Growth Factors for Pulp Regeneration.
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin.
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
METTL1-modulated LSM14A facilitates proliferation and migration in glioblastoma via the stabilization of DDX5.
Glutamate rescues heat stress-induced apoptosis of Sertoli cells by enhancing the activity of antioxidant enzymes and activating the Trx1-Akt pathway in vitro.
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca(2+) antagonism and maintaining mitochondrial function.
Osteoblast Attachment on Bioactive Glass Air Particle Abrasion-Induced Calcium Phosphate Coating.
HBV infection effects prognosis and activates the immune response in intrahepatic cholangiocarcinoma.
Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.
Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
USP54 is a potential therapeutic target in castration-resistant prostate cancer.
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
Arctigenin promotes mucosal healing in ulcerative colitis through facilitating focal adhesion assembly and colonic epithelial cell migration via targeting focal adhesion kinase.
LncRNA MYOSLID contributes to PH via targeting BMPR2 signaling in pulmonary artery smooth muscle cell.
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells.
CRISPR/Cas13 sgRNA-Mediated RNA-RNA Interaction Mapping in Live Cells with APOBEC RNA Editing.
Scutellaria barbata D.Don and Scleromitrion diffusum (Willd.) R.J.Wang inhibits the progression of triple negative breast cancer though the activation inhibition of NF-κB triggered by CAFs-derived IL6.
Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation.
Mitochondrial transplantation rescues Ca(2+) homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy.
H(2)S-releasing oridonin derivatives with improved antitumor activity by inhibiting the PI3K/AKT pathway.
Polydatin, a potential NOX5 agonist, synergistically enhances antitumor activity of cisplatin by stimulating oxidative stress in non‑small cell lung cancer.
Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.
Triptolide-induced cuproptosis is a novel antitumor strategy for the treatment of cervical cancer.
Mito-LND and (E)-Akt inhibitor-IV: novel compounds inducing endoplasmic reticulum stress and ROS accumulation against hepatocellular carcinoma.
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.
A NRF2 Regulated and the Immunosuppressive Microenvironment Reversed Nanoplatform for Cholangiocarcinoma Photodynamic-Gas Therapy.
Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides.
Fatty liver disease protective MTARC1 p.A165T variant reduces the protein stability of MTARC1.
Sea Buckthorn Polyphenols Alleviate High-Fat-Diet-Induced Metabolic Disorders in Mice via Reprograming Hepatic Lipid Homeostasis Owing to Directly Targeting Fatty Acid Synthase.
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus.
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides.
Predicting lung adenocarcinoma prognosis, immune escape, and pharmacomic profile from arginine and proline-related genes.
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.
Regorafenib activates oxidative stress by inhibiting SELENOS and potentiates oxaliplatin-induced cell death in colon cancer cells.
An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing.
Multiomics characterization and verification of clear cell renal cell carcinoma molecular subtypes to guide precise chemotherapy and immunotherapy.
p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP.
Nanofibrous PCL-Based Human Trabecular Meshwork for Aqueous Humor Outflow Studies.
Osteocyte β3 integrin promotes bone mass accrual and force-induced bone formation in mice.
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis.
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells.
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities.
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells.
Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33.
Identification of c-Met as a novel target of γ-glutamylcyclotransferase.
Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells.
Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1.
Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression.
Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury.
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury.
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
GEF-H1 Transduces FcεRI Signaling in Mast Cells to Activate RhoA and Focal Adhesion Formation during Exocytosis.
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells.
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Perinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner.
A subset of VEGFR-TKIs activates AMPK in LKB1-mutant lung cancer.
Klotho protects chromosomal DNA from radiation-induced damage.
RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mTOR pathway.
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling.
Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.
Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility.
Oxidant stress-sensitive circRNA Mdc1 controls cardiomyocyte chromosome stability and cell cycle re-entry during heart regeneration.
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency.
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
Antifouling poly(PEGMA) grafting modified titanium surface reduces osseointegration through resisting adhesion of bone marrow mesenchymal stem cells.
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development.
Induction of Stem-Cell-Derived Cardiomyogenesis by Fibroblast Growth Factor 10 (FGF10) and Its Interplay with Cardiotrophin-1 (CT-1).
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification.
Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the presence of lipopolysaccharide.
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
JCI‑20679 suppresses the proliferation of glioblastoma stem cells by activating AMPK and decreasing NFATc2 expression levels.
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis.
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus.
Five hypoxia and immunity related genes as potential biomarkers for the prognosis of osteosarcoma.
Modular assembly of the principal microtubule nucleator γ-TuRC.
The osteogenic effects of porous Tantalum and Titanium alloy scaffolds with different unit cell structure.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Dihydroartemisinin enhances the anti-tumor activity of oxaliplatin in colorectal cancer cells by altering PRDX2-reactive oxygen species-mediated multiple signaling pathways.
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Fibrous Structure and Stiffness of Designer Protein Hydrogels Synergize to Regulate Endothelial Differentiation of Bone Marrow Mesenchymal Stem Cells.
Three-Dimensionally Printed Ti2448 With Low Stiffness Enhanced Angiogenesis and Osteogenesis by Regulating Macrophage Polarization via Piezo1/YAP Signaling Axis.
The Recurrent Mutation in PATL2 Inhibits Its Degradation Thus Causing Female Infertility Characterized by Oocyte Maturation Defect Through Regulation of the Mos-MAPK Pathway.
The forkhead box transcription factor FoxP4 regulates thermogenic programs in adipocytes.
BRCA1 Antibodies Matter.
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Browning of adipose tissue and increased thermogenesis induced by Methotrexate.
Disorganization of intercalated discs in dilated cardiomyopathy.
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling.
SPEG binds with desmin and its deficiency causes defects in triad and focal adhesion proteins.
Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model.
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis.
DDX52 knockdown inhibits the growth of prostate cancer cells by regulating c-Myc signaling.
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
Oscillating Magnetic Field Regulates Cell Adherence and Endothelialization Based on Magnetic Nanoparticle-Modified Bacterial Cellulose.
The mRNA levels of heat shock factor 1 are regulated by thermogenic signals via the cAMP-dependent transcription factor ATF3.
ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite ETS/E-box motifs.
HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer.
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.
Regulation of hepatic glutamine metabolism by miR-122.
Long noncoding RNA expression analysis reveals the regulatory effects of nitinol-based nanotubular coatings on human coronary artery endothelial cells.
Micro- and Nanohemispherical 3D Imprints Modulate the Osteogenic Differentiation and Mineralization Tendency of Bone Cells.
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Danggui Buxue Tang promotes the adhesion and migration of bone marrow stromal cells via the focal adhesion pathway in vitro.
BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells.
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Transcriptional Regulation of ZNF638 in Thermogenic Cells by the cAMP Response Element Binding Protein in Male Mice.
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
CRMP4a suppresses cell motility by sequestering RhoA activity in prostate cancer cells.
Recurrent Loss of APOBEC3H Activity during Primate Evolution.
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer.
The impact of photofunctionalized gold nanoparticles on osseointegration.
Focal adhesions are involved in simulated-microgravity-induced basilar and femoral arterial remodelling in rats.
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
ProBDNF inhibits collective migration and chemotaxis of rat Schwann cells.
Gao W, Pan F, Qiu K, Ou C, Tian F, Yu C
Frontiers in cell and developmental biology 2026;14:1722916
Frontiers in cell and developmental biology 2026;14:1722916
Global stabilization of the transcriptome in mitotic cells.
Khalizeva E, Latifkar A, Xiang K, Bartel DP, Ly J, Cheeseman IM
The EMBO journal 2026 May;45(10):3563-3588
The EMBO journal 2026 May;45(10):3563-3588
Mitochondrial control of glycerolipid synthesis by a PEP shuttle.
Yamamuro T, Katoh D, Silva GM, Nishida H, Oikawa S, Higuchi Y, Wang D, Fujimoto M, Yoshida N, Li M, Shin J, Zhao Z, Yook JS, Sun L, Kajimura S
Cell 2026 May 14;189(10):2988-3003.e23
Cell 2026 May 14;189(10):2988-3003.e23
p53 and fatty acids collaborate to trigger ferroptosis via the FBXO2-FABP5 axis in colorectal cancer.
Tong J, Han T, Deng J, Gan Y, Ruan R, Zhao W, Xiong C, Liao Q, Chen S, Bu H, Xiong J, Zhou X, Hao Q
Redox biology 2026 Mar;90:104043
Redox biology 2026 Mar;90:104043
VAMP8 function reveals tight linkage between endocytic recycling and endocytosis.
Liu A, Li Y, Huang Z, Chen W, Xu P, Wei X, Hu G, Liu S, Liu X, He Y, Wang D, Schmid SL, Chen Z
Proceedings of the National Academy of Sciences of the United States of America 2026 Mar 31;123(13):e2602991123
Proceedings of the National Academy of Sciences of the United States of America 2026 Mar 31;123(13):e2602991123
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Du T, Yao L, Wang W, Li Z, Dong J, Zhou Z, Shi C, Ge X, Ma R, Chen L, Xiang Y, He Z, Zheng L, Xu Y, Cao C, Jing J, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Knockdown of Ddx3x in mPFC induces autistic-like phenotype in mice via altered synaptic plasticity.
Zhuang H, Cao X, Tang X, Liang Z, Wang H, Liu Q, Yan X, Lin X, Su X, Wang M, Huang Y, Lu D, Wang Y, Chen H, Shen L
Translational psychiatry 2026 Mar 30;16(1)
Translational psychiatry 2026 Mar 30;16(1)
DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling-Mediated Anti-tumor Immunity.
Huang K, Dai X, Li S, Chen Y, Yu Y, Wang L, Liu K, Lyu S, Li C, Sun Y, Li F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 29;:e17634
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 29;:e17634
Pro-Inflammatory Activation Promotes Atherogenic Endothelial Phenotype in Male and Female Human Umbilical Endothelial Vein Cells (HUVECs).
Lorenz M, Palant R, Oscherowa E, Karmid-Haj Hamoud W, Kirwan JA, Trajkovski S, Wiebach J, Fritsche-Guenther R, Wu H, Haritonow N, Vietzke A, Kaschina E, Henrich W, Temp J, Barcena ML
International journal of molecular sciences 2026 Mar 27;27(7)
International journal of molecular sciences 2026 Mar 27;27(7)
Structurally-defined non-cationic docosahexaenoic acid based siRNA-micelles for safe and effective combinatorial glioblastoma therapy.
Xu S, Fan M, Ding Q, Wang Y, Ismail M, Ruan W, Zou Y, Zhang D, Zheng M
Journal of controlled release : official journal of the Controlled Release Society 2026 Mar 10;391:114568
Journal of controlled release : official journal of the Controlled Release Society 2026 Mar 10;391:114568
Mitochondrial control of glycerolipid synthesis by a PEP shuttle.
Yamamuro T, Katoh D, Silva GM, Nishida H, Oikawa S, Higuchi Y, Wang D, Fujimoto M, Yoshida N, Li M, Shin J, Zhao Z, Yook JS, Sun L, Kajimura S
bioRxiv : the preprint server for biology 2026 Mar 10;
bioRxiv : the preprint server for biology 2026 Mar 10;
Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer.
Ma S, Ma Z, Shen J, Liu H, Yang H, Hu Y, Ying S
Oncology letters 2026 Jan;31(1):41
Oncology letters 2026 Jan;31(1):41
Unraveling the antidepressant mechanisms of JiaWeiSiNiSan: Insights from network pharmacology and experimental validation.
Qiu Z, Hu L, Yuan E, Ai Z, Liu R, Li H
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120745
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120745
Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma.
Chianese U, Papulino C, Saggese G, Ali A, Ciotola M, Lonardo E, Cortese M, Favale G, Di Mauro A, La Gioia D, Golino V, Sommella E, Campiglia P, Franco R, Ciardiello F, De Vita F, Carafa V, Altucci L, Benedetti R
Signal transduction and targeted therapy 2026 Jan 20;11(1):25
Signal transduction and targeted therapy 2026 Jan 20;11(1):25
Transcriptomics-guided high-throughput drug screening identifies potent therapies for P53 pathway altered DIPG/DMG.
Jiang Z, Xie L, Zhou H, Geng Y, Xiao X, Li T, Deng Y, Zhang M, Shan S, Xu C, Zhang L
Neuro-oncology 2026 Jan 1;28(1):251-267
Neuro-oncology 2026 Jan 1;28(1):251-267
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Fan JB, Qin LQ, Ding L, Zhang L, Shao MM, Tong X, Xu JY
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Environmentally relevant lanthanum chloride exposure induces hepatic steatosis in zebrafish larvae via PPARα-dependent ApoB suppression.
Li K, Zhao X, Xie Z, Wu Q, Jia W, Zhou X, Gao X, Zeng P, Li J, Niu Q, Qi Z, Cui M, Song W
Communications biology 2026 Feb 9;9(1)
Communications biology 2026 Feb 9;9(1)
Cis and Trans Regulatory Mechanisms of ecDNA Segregation.
Xie Y, Lim JYS, Liu W, Gilbreath C, Sun X, Qiao K, Kim YJ, Wu S
bioRxiv : the preprint server for biology 2026 Feb 5;
bioRxiv : the preprint server for biology 2026 Feb 5;
FBXO22 targets ubiquitination and degradation of c-Cbl in leukemia.
Li J, Ma L, Wang J, Xu W, Cheng Y, Zhang J, Cao H, Wang Y, Wang Z, Xu H, Li Y, Zhang Y
Scientific reports 2026 Feb 26;16(1)
Scientific reports 2026 Feb 26;16(1)
Bioadhesive Scaffold for Dual Delivery of Methotrexate-Loaded Liposomes and Chondrogenic miRNA in Advanced Rheumatoid Arthritis Therapy.
Hu Y, Yan L, Xv D, Ran J, Hou Y, Zheng J, Wu Z, Kuai X, Lu X, Xie C, Han L
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(21):e11882
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(21):e11882
Characterization of NLRP3 Inflammasome-Associated Hub Genes in the Progression of Diabetic Nephropathy.
Zhao S, Li Y, Li W, Dong L, Lian R, Luo Q, Lian X, Li J, He F
Immunity, inflammation and disease 2026 Apr;14(4):e70424
Immunity, inflammation and disease 2026 Apr;14(4):e70424
Versatile CRISPR-Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System.
Shi M, Ge W, Li C, Liu B, Deng X, Liu C, Zheng M, Zhang P, Li L, Guo Y, Han Y, Yang Y, Yu YV, Jin YN
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e11485
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e11485
Treatment of Huntington's disease with a pan-HTT-targeting CRISPR nuclease.
Tan K, Del Bosque Siller D, Xiong AY, Wang AXA, McCallister TX, Mummadi S, St John LA, Lee TK, Carrillo AN, Renshaw DG, Zhou RH, Lim CKW, He J, Fields CJ, Hayden MR, Gaj T
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Apr 24;
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Apr 24;
Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress.
Guan H, Huang L, Liu Y, Zhu E, Chen L, Li W, Wu H, Zhang X, Qin R, Zheng J, Mo Y, Zhong M, Xu B, Dai X, Wei Q, Chen Y, Wang Q, Zheng Z, Ma K, Tang C
Journal of inflammation research 2025;18:11521-11538
Journal of inflammation research 2025;18:11521-11538
Extracellular vesicles-miR-205-5p inhibits lymphatic metastasis in pancreatic cancer through diffusely downregulating VEGFA.
Wang Y, Qin C, Zhao Y, Zhao B, Li Z, Li T, Zhang X, Wang W
Journal of Cancer 2025;16(7):2197-2211
Journal of Cancer 2025;16(7):2197-2211
Network pharmacology combined with molecular docking and experimental validation of the mechanism of action of columbianetin acetate in the treatment of ovarian cancer.
Hu M, Wang L, Zhang F, Xie Y, Zhang T, Liu H, Li Z, Zhang J
Frontiers in oncology 2025;15:1515976
Frontiers in oncology 2025;15:1515976
Exploring the Functional Role of Programmed Death-Ligand 1 (PD-L1) in the Castration-Resistant Prostate Cancer Using Transcriptomic Sequencing Analysis.
Zhong L, Zhang P, Ji J, Mao J, Li L
Cancer medicine 2025 Sep;14(17):e71225
Cancer medicine 2025 Sep;14(17):e71225
Genome-wide mapping of RNA-protein associations through sequencing.
Qi Z, Xue S, Chen J, Zhao W, Johnson K, Wen X, Charles Richard JL, Lin P, Zhong S
Nature biotechnology 2025 Sep 9;
Nature biotechnology 2025 Sep 9;
Erucic acid impairs male fertility by suppressing retinoic acid synthesis in sertoli cells.
Jiaming S, Xie G, Xinlong W, Jun J, Yijian X, Ting T, Zhaowanyue H, Jinzhao M, Chun C, Tian D, Rujun M, Kai Z, Zhiyong L, Hongli Y, Bing Y
Ecotoxicology and environmental safety 2025 Sep 15;303:118971
Ecotoxicology and environmental safety 2025 Sep 15;303:118971
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
The individual isoforms of ORMDL, the regulatory subunit of serine palmitoyltransferase, have distinctive sensitivities to ceramide.
Mahawar U, Davis DL, Kannan M, Suemitsu J, Oltorik CD, Farooq F, Fulani R, Weintraub C, Wattenberg B
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159677
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159677
Androgen regulates seasonal changes in triglyceride synthesis through the AR-SREBP1-FASN axis in the scented glands of muskrats (Ondatra zibethicus).
Shi X, Gao Q, Lu W, Xie Y, Zhang H, Zhang D, Liu Y, Weng Q
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159675
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159675
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
Cheng L, Li H, Xie C, Kuang K, Wan B, Chen P, Sui H, Zhao Q, Cho N, Cui R
Bioorganic chemistry 2025 Oct;165:109010
Bioorganic chemistry 2025 Oct;165:109010
The PDGFBB-PDGFRβ Pathway and Laminins in Pericytes Are Involved in the Temporal Change of AQP4 Polarity during Temporal Lobe Epilepsy Pathogenesis.
Lin L, Tang H, Cui K, Kang Z, Pan T, Feng C, Zhao X, Wang J, Chen Z, Jiang Z, Wu G
eNeuro 2025 Oct;12(10)
eNeuro 2025 Oct;12(10)
Simultaneously induce apoptosis and inhibiting metastasis of Triple negative breast cancer Enabled by a highly potent NIR fluorescent inhibitor.
Zhao Q, Wu J, Yao J, Liu Z, Li C, Sun Q
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2025 Oct 15;339:126183
PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.
Zhou H, Sun S, Liu H, Li T, Xu Y, Yang R, Liu H, He L, Xu W, Guan S, Xu J
Antioxidants (Basel, Switzerland) 2025 Oct 11;14(10)
Antioxidants (Basel, Switzerland) 2025 Oct 11;14(10)
Differential cell survival outcomes in response to diverse amino acid stress.
Russier M, Fiore A, Bici A, Groß A, Tanzer M, Yeroslaviz A, Mann M, Murray PJ
Life science alliance 2025 Nov;8(11)
Life science alliance 2025 Nov;8(11)
The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity.
Zhang H, Guo Z, Wei G, Yi J, Wang Z, Zhang Y, Zhao H, Ren T, Wang Y, Kuang J, Sheng Z, Zhang D
EMBO reports 2025 Nov;26(21):5300-5325
EMBO reports 2025 Nov;26(21):5300-5325
C1orf50 Accelerates Epithelial-Mesenchymal Transition and the Cell Cycle of Hepatocellular Carcinoma.
Tanaka A, Otani Y, Maekawa M, Rogachevskaya A, Peña T, Chin VD, Toyooka S, Roehrl MH, Fujimura A
Cancer genomics & proteomics 2025 Nov-Dec;22(6):836-849
Cancer genomics & proteomics 2025 Nov-Dec;22(6):836-849
Dihydromyricetin exerts dual anti-acne actions by suppressing propionibacterium acnes proliferation and host inflammatory responses via TLR2/NF-κB/MAPK pathway inhibition.
Jin L, Li R, Zhou X, Chen W, Chen X, Zhu W
European journal of pharmacology 2025 Nov 5;1006:178161
European journal of pharmacology 2025 Nov 5;1006:178161
The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.
Li J, He M, Huang M, Xiang J, Zhang L, Liu Y, Ma Y, Zeng X, Sun X
Scientific reports 2025 Nov 4;15(1):38574
Scientific reports 2025 Nov 4;15(1):38574
Epigenetic regulation of ACSL4 via H2A monoubiquitylation connects lipid metabolism to BAP1-mediated ferroptosis.
Fan K, Zhou S, Ren Y, Xiong J, Wang H, Fu Y, Chen Y, Wang B, Fan K, Gao M, Guo T, Wei X, Jiao L, Shi J, Ding C, Zhang Y
Cell death and differentiation 2025 Nov 27;
Cell death and differentiation 2025 Nov 27;
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment.
Qiao K, Yang QL, Li T, Chen X, Yazgan Z, Kim YJ, Gilbreath C, Stanley Lim JY, Xie Y, Sun X, Liu Y, Jia Y, Chen ZJ, Huang H, Wu S
bioRxiv : the preprint server for biology 2025 Nov 16;
bioRxiv : the preprint server for biology 2025 Nov 16;
Dihydrotanshinone I potentiates the anti-tumor activity of cisplatin by activating ROS-mediated ER stress through targeting HSPD1 in lung cancer cells.
Lin H, Sui H, Yu Y, Xie C, Shen Y, Cheng L, Wang J, Yu Y, Xie C, Cui R
European journal of pharmacology 2025 May 5;994:177378
European journal of pharmacology 2025 May 5;994:177378
STIM1/2 maintain signaling competence at ER-PM contact sites during neutrophil spreading.
Rabesahala de Meritens C, Carreras-Sureda A, Rosa N, Pick R, Scheiermann C, Demaurex N
The Journal of cell biology 2025 May 5;224(5)
The Journal of cell biology 2025 May 5;224(5)
Modulation of Filopodial Myosin Function.
Crawford A, Schwartz JK, Hall E, Houdusse A, Titus MA
bioRxiv : the preprint server for biology 2025 May 29;
bioRxiv : the preprint server for biology 2025 May 29;
Indole-3-lactic acid derived from tryptophan metabolism promotes trophoblast migration and invasion by activating the AhR/VCAN pathway.
Wei Y, Wei M, Zhang L, Jia L, Huang X, Duan T, He Q, Wang K
Placenta 2025 May 23;165:4-15
Placenta 2025 May 23;165:4-15
Vascular grafts with a mimetic microenvironment extracted from extracellular matrix of adipocytes can promote endothelialization in vivo.
Wang J, Xu M, Liu H, Wang D, Zhang H, Xu Z, Shi X, Liu X, Tan Z
Acta biomaterialia 2025 May 15;198:49-62
Acta biomaterialia 2025 May 15;198:49-62
Inherited deficiency of DIAPH1 identifies a DNA double strand break repair pathway regulated by γ-actin.
Woodward BL, Lahiri S, Chauhan AS, Garcia MR, Goodley LE, Clarke TL, Pal M, Agathanggelou A, Jhujh SS, Ganesh AN, Hollins FM, Deforie VG, Maroofian R, Efthymiou S, Meinhardt A, Mathew CG, Simpson MA, Mefford HC, Faqeih EA, Rosenzweig SD, Volpi S, Di Matteo G, Cancrini C, Scardamaglia A, Shackley F, Davies EG, Ibrahim S, Arkwright PD, Zaki MS, Stankovic T, Taylor AMR, Mazur AJ, Di Donato N, Houlden H, Rothenberg E, Stewart GS
Nature communications 2025 May 14;16(1):4491
Nature communications 2025 May 14;16(1):4491
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Wang X, Li J, Zhu Y, Shen H, Ding J, Zeng T, Min W, Liang SQ, Huang L, Shi Z, Shen H, Huang F, Yuan K, Kuang W, Ji M, Sun C, Hou Y, Wang L, Chen W, Jiang Y, Hao H, Xiao Y, Yang P
Nature cancer 2025 Mar;6(3):474-492
Nature cancer 2025 Mar;6(3):474-492
Exosomal miR-184 facilitates bladder cancer progression by targeting AKR1C3 and inducing immune escape via IRF2-CXCL10 axis.
Ying W, Zhao Y, He Y, Deng Y, Gan X, Li P, Chen X, Ding Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167627
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167627
Loss of MNX1 Sensitizes Tumors to Cytotoxic T Cells by Degradation of PD-L1 mRNA.
Li Z, Chen L, Zhang G, Wang S, Xu E, Teng J, Xu J, Peng F, Min Q, Wang Z, Shao S, Zhao L, Shan B, Wang Y, Zhan Q, Liu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403077
Intratumoral Collagen Deposition Supports Angiogenesis Suggesting Anti-angiogenic Therapy in Armored and Cold Tumors.
Mei J, Yang K, Zhang X, Luo Z, Tian M, Fan H, Chu J, Zhang Y, Ding J, Xu J, Cai Y, Yin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2409147
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2409147
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
Liehr T, Kankel S, Hardt KS, Buhl EM, Noels H, Keller DT, Schröder-Lange SK, Weiskirchen R
Cells 2025 Mar 28;14(7)
Cells 2025 Mar 28;14(7)
The individual isoforms of ORMDL, the regulatory subunit of serine palmitoyltransferase, have distinctive sensitivities to ceramide.
Mahawar U, Davis DL, Kannan M, Suemitsu J, Oltorik CD, Farooq F, Fulani R, Weintraub C, Allegood J, Wattenberg B
bioRxiv : the preprint server for biology 2025 Mar 21;
bioRxiv : the preprint server for biology 2025 Mar 21;
Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo.
Lu Y, Yan Z, Sun J, Wang C, Xu L, Lyu X, Wang X, Lou J, Huang H, Meng L, Zhao Y
Journal of medicinal chemistry 2025 Mar 13;68(5):5616-5640
Journal of medicinal chemistry 2025 Mar 13;68(5):5616-5640
Noscapine derivative 428 suppresses ferroptosis through targeting GPX4.
Zhang Y, Shi H, Wang Y, Liu W, Li G, Li D, Wu W, Wu Y, Zhang Z, Ji Y, Zhu C, Bai W, Lei H, Xu H, Zhong H, Han B, Yang L, Liu L, Wang W, Zhao Y, Zhang Y, Wu Y
Redox biology 2025 Jun;83:103635
Redox biology 2025 Jun;83:103635
Polygonati kingianum polysaccharide alleviates dextran sulfate sodium-induced colitis by modulating gut microbiota and metabolic homeostasis.
Fan H, Zhao H, Zheng Y, Chen G, Ji Y, Yu W, Yan J, Yang H, Liang X, Chen Y
International journal of biological macromolecules 2025 Jun;316(Pt 2):144836
International journal of biological macromolecules 2025 Jun;316(Pt 2):144836
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
Li G, Ni R, Shi Z, Mao H, Luo Y, Cao X, Zhang C, Liu Y, Jin Z, Chen J, Fu J, Zhang H, Zhu Y
International journal of biological macromolecules 2025 Jun;312:144042
International journal of biological macromolecules 2025 Jun;312:144042
Alpha-1 antitrypsin modulates neutrophil phenotype and function: implications for inflammatory regulation.
Oshins R, Patel I, Khartabil L, Katikaneni DS, Scindia Y, Khodayari N
Journal of leukocyte biology 2025 Jun 4;117(6)
Journal of leukocyte biology 2025 Jun 4;117(6)
Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2.
Zhang K, Ji Y, Fu Z, Wang X, Zhang Y, Yang Y, Liu R, Chen X, Cai G, Hong Q
Journal of cellular and molecular medicine 2025 Jul;29(14):e70732
Journal of cellular and molecular medicine 2025 Jul;29(14):e70732
Constitutive HIF-1α Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation.
Boix J, Knuever J, Niehoff N, Sen A, Pla-Martin D, Baris OR, Etich J, Brachvogel B, Kaul H, Isbrandt D, Soroka E, Bazzi H, Wenger RH, Giavalisco P, Wiesner RJ
The Journal of investigative dermatology 2025 Jul;145(7):1683-1692.e8
The Journal of investigative dermatology 2025 Jul;145(7):1683-1692.e8
Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.
Teng X, Wang Y, Huang H, Ding Y, Wang J, Liu M, Song K, Shao L, Yu Y, Yang Z, Shen Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501112
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501112
Hexahydrocurcumin suppresses hepatocellular carcinoma by regulating TRIM23/MBNL1 pathway.
Wang M, Weng C, Xu J, Xu K
Scientific reports 2025 Jul 2;15(1):22541
Scientific reports 2025 Jul 2;15(1):22541
E3 ligase TRIM22 promotes melanoma proliferation by regulating cell cycle progression through K63-linked ubiquitination of p21.
Jin CX, Feng TZ, Ji X, Liu YS, Qin HN, Teng YB, Sampson C, Xia T, Piao HL, Liu JW
Scientific reports 2025 Jul 1;15(1):22311
Scientific reports 2025 Jul 1;15(1):22311
Disruption of Ferroptosis Inhibition and Immune Evasion with Tumor-Activatable Prodrug for Boosted Photodynamic/Chemotherapy Eradication of Drug-Resistant Tumors.
Bi T, Zhao Q, Wang T, Huang R, Liu B, Liu X, Wang Y, Sun Q, Yang Y, Liu Z
Advanced healthcare materials 2025 Jan;14(2):e2403473
Advanced healthcare materials 2025 Jan;14(2):e2403473
Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation.
Ruan J, Wei X, Li S, Ye Z, Hu L, Zhuang R, Cao Y, Wang S, Wu S, Peng D, Chen S, Yuan S, Xu A
Cell discovery 2025 Jan 21;11(1):4
Cell discovery 2025 Jan 21;11(1):4
Decoding the general role of tRNA queuosine modification in eukaryotes.
Díaz-Rullo J, González-Moreno L, Del Arco A, González-Pastor JE
Scientific reports 2025 Jan 2;15(1):345
Scientific reports 2025 Jan 2;15(1):345
Tubeimoside-I, an inhibitor of HSPD1, enhances cytotoxicity of oxaliplatin by activating ER stress and MAPK signaling pathways in colorectal cancer.
Wu T, Yu Y, Tu X, Ye L, Wang J, Xie C, Kuang K, Yu Y, Zhuge W, Wang Z, Cui R, Zheng Y
Journal of ethnopharmacology 2025 Jan 10;336:118754
Journal of ethnopharmacology 2025 Jan 10;336:118754
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism.
Kim YC, Das V, Kanoo S, Yao H, Stanford SM, Bottini N, Karihaloo A, Vallon V
American journal of physiology. Renal physiology 2025 Jan 1;328(1):F68-F81
American journal of physiology. Renal physiology 2025 Jan 1;328(1):F68-F81
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Yu Z, Wang Z, Chen Y, Wang Y, Tang L, Xi Y, Lai K, Zhang Q, Li S, Xu D, Tian A, Wu M, Wang Y, Yang G, Gao C, Huang T
Biomaterials 2025 Feb;313:122772
Biomaterials 2025 Feb;313:122772
Metabolic dysfunction in mice with adipocyte-specific ablation of the adenosine A2A receptor.
Verma N, Perie L, Silvestro M, Verma A, Cronstein BN, Ramkhelawon B, Mueller E
The Journal of biological chemistry 2025 Feb;301(2):108206
The Journal of biological chemistry 2025 Feb;301(2):108206
Inhibition of Endoplasmic Reticulum Stress Cooperates with SLC7A11 to Promote Disulfidptosis and Suppress Tumor Growth upon Glucose Limitation.
Wang J, Chen J, Fan K, Wang M, Gao M, Ren Y, Wu S, He Q, Tu K, Xu Q, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2408789
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2408789
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
Tang H, Han S, Jie Y, Jiang X, Zhang Y, Peng J, Wang F, Li X, Zhou X, Jiang W, Weng X
Nucleic acids research 2025 Feb 27;53(5)
Nucleic acids research 2025 Feb 27;53(5)
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers.
Li K, Yu X, Xu Y, Wang H, Liu Z, Wu C, Luo X, Xu J, Fang Y, Ju E, Lv S, Chan HF, Lao YH, He W, Tao Y, Li M
Nature communications 2025 Feb 14;16(1):1629
Nature communications 2025 Feb 14;16(1):1629
SAMD9L inhibits flavivirus translation independently of its capacity to trigger innate immune response.
Cannac M, Zoladek J, Bribes I, Fresneau-Resende M, Legrand A, Demeure R, Zusinaite E, Merits A, Etienne L, Nisole S
PLoS pathogens 2025 Dec;21(12):e1013773
PLoS pathogens 2025 Dec;21(12):e1013773
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.
Bigi A, Conti AC, Napolitano L, Fusco G, De Simone A, Chiti F, Cascella R, Cecchi C
Cell & bioscience 2025 Dec 9;15(1):166
Cell & bioscience 2025 Dec 9;15(1):166
Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.
de la Calle Arregui C, Frank AR, Mun K, Kim J, Majmudar K, Bishop JA, Lewis C, Xie Y, McFadden DG
bioRxiv : the preprint server for biology 2025 Dec 9;
bioRxiv : the preprint server for biology 2025 Dec 9;
Genetic characterization and screening of congenital adrenal hyperplasia by long-read sequencing in a cohort of 21,239 newborns.
Liang D, Zhu M, Liang Q, Qiang R, Yu L, Xu S, Li M, Song J, Zhou Y, He X, Huang Y, Jin H, Tan J, Liu H, Xia A, Liu Y, Liu P, Li Z, Wang R, Wang D, Zhang R, Pu Q, Zhou J, Xu R, Wang X, Tan M, Chen D, Wu C, Cui D, Mao A, Zhou W, Qiu W, Wu L
Genome medicine 2025 Dec 30;18(1):15
Genome medicine 2025 Dec 30;18(1):15
Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.
Li J, Li Y, Zhou X, Yang S, Liu D, Wen H, Chen X, Duan C, Yu M, Zhang M, Tang B, Wang Y, Wang L, Wu Y
Signal transduction and targeted therapy 2025 Dec 3;10(1):394
Signal transduction and targeted therapy 2025 Dec 3;10(1):394
Treatment of Huntington's disease with a pan-HTT-targeting CRISPR nuclease.
Tan K, Siller DDB, Xiong AY, Wang AXA, McCallister TX, Mummadi S, St John LA, Lee TK, Carrillo A, Renshaw DG, Zhou RH, Lim CKW, He J, Fields CJ, Hayden MR, Gaj T
bioRxiv : the preprint server for biology 2025 Dec 22;
bioRxiv : the preprint server for biology 2025 Dec 22;
TCF19 promotes gastric cancer progression through MCM6.
Zhang J, Liu Y, Chen S, Pang Y, Zeng J, An J
BMC gastroenterology 2025 Dec 15;26(1):45
BMC gastroenterology 2025 Dec 15;26(1):45
Single-cell, spatial and bulk transcriptome data analysis revealed LINC00467-mediated Sertoli cell ferroptosis is a potential therapeutic target and biomarker for azoospermia.
Bo H, Zhu F, Zhao X, Du L, Zhou Q, Liu L, Lv S, Zhang H, Fan L
Free radical biology & medicine 2025 Dec 1;240:650-662
Free radical biology & medicine 2025 Dec 1;240:650-662
Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention.
Tan L, Wang Y, Huyan C, Li M, Liu D, Liu M, Luo Z, Cai K, Hu Y
Acta biomaterialia 2025 Aug;202:170-192
Acta biomaterialia 2025 Aug;202:170-192
Reduction in vinculin levels with Rb1 loss is responsible for altered differentiation in preosteoblasts.
Pendleton E, Abdallah K, Chandar N
Experimental cell research 2025 Aug 1;451(1):114690
Experimental cell research 2025 Aug 1;451(1):114690
Mitoxantrone-Encapsulated ZIF-8 Enhances Chemo-Immunotherapy via Amplified Immunogenic Cell Death.
Li J, Lv W, Han Z, Li Y, Deng J, Huang Y, Wan S, Sun J, Dai B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2501542
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2501542
HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis.
Peng X, Sun B, Tang C, Shi C, Xie X, Wang X, Jiang D, Li S, Jia Y, Wang Y, Tang H, Zhong S, Piao M, Cui X, Zhang S, Wang F, Wang Y, Na R, Huang R, Jiang Y, Zhang W, Xu J, Lin K, Guo J, Pan Z, Wang K, Zhao Q, Liu H, Yu B, Ji Y, Zhang J, Li S, Tian J
Developmental cell 2025 Apr 7;60(7):1070-1086.e8
Developmental cell 2025 Apr 7;60(7):1070-1086.e8
Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer.
Deng R, Fu L, Liang H, Ai X, Liu F, Li N, Wu L, Li S, Yang X, Lin Y, Huang Y, Yun J
Cell death & disease 2025 Apr 5;16(1):254
Cell death & disease 2025 Apr 5;16(1):254
FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release.
Chen X, Liu H, Huang Y, Li L, Jiang X, Liu B, Li N, Zhu L, Liu C, Xiao J
International journal of molecular sciences 2025 Apr 24;26(9)
International journal of molecular sciences 2025 Apr 24;26(9)
Usutu virus NS4A induces autophagy and is targeted by the selective autophagy receptor p62/SQSTM1 for degradation.
Nelemans T, Tas A, de Beijer NL, Janssen GMC, van Veelen PA, van Hemert MJ, Kikkert M
Virology journal 2025 Apr 17;22(1):103
Virology journal 2025 Apr 17;22(1):103
Transcription factor MEF2D regulates aberrant expression of ACSL3 and enhances sorafenib resistance by inhibiting ferroptosis in HCC.
Li X, Chen S, Shi Y, Wang Y, Wang X, Lin Q, Wu C, Fang W, Sun P, Ma L
Frontiers in pharmacology 2024;15:1464852
Frontiers in pharmacology 2024;15:1464852
SENP3 sensitizes macrophages to ferroptosis via de-SUMOylation of FSP1.
Chen X, Wang J, Yang P, Liu HY, Zhong S, Lu C, Gao M, Liu D, Zhang J, Wang J, Ma S, Wang W, Zhu H, Zhang X, Liu Y
Redox biology 2024 Sep;75:103267
Redox biology 2024 Sep;75:103267
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains.
Beigl TB, Paul A, Fellmeth TP, Nguyen D, Barber L, Weller S, Schäfer B, Gillissen BF, Aulitzky WE, Kopp HG, Rehm M, Andrews DW, Pluhackova K, Essmann F
EMBO reports 2024 Sep;25(9):3896-3924
EMBO reports 2024 Sep;25(9):3896-3924
Granulosa Cell-Layer Stiffening Prevents Escape of Mural Granulosa Cells from the Post-Ovulatory Follicle.
Wang X, Liao J, Shi H, Zhao Y, Ke W, Wu H, Liu G, Li X, He C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2403640
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2403640
Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention.
Zou ZY, Ren TY, Li JQ, Jiao TY, Wang MY, Huang LJ, Lin SZ, Wang YY, Guo XZ, Song YY, Yang RX, Xie C, Fan JG
Journal of clinical and translational hepatology 2024 Sep 28;12(9):765-779
Journal of clinical and translational hepatology 2024 Sep 28;12(9):765-779
Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation and Pyroptosis.
Cao D, Xi R, Li H, Zhang Z, Shi X, Li S, Jin Y, Liu W, Zhang G, Liu X, Dong S, Feng X, Wang F
Journal of medicinal chemistry 2024 Sep 12;67(17):15873-15891
Journal of medicinal chemistry 2024 Sep 12;67(17):15873-15891
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Chang Y, Wang X, Yang J, Tien JC, Mannan R, Cruz G, Zhang Y, Vo JN, Magnuson B, Mahapatra S, Cho H, Dhanasekaran SM, Wang C, Wang Z, Zhou L, Zhou K, Zhou Y, Zhang P, Huang W, Xiao L, Liu WR, Hamadeh R, Su F, Wang R, Miner SJ, Cao X, Cheng Y, Mehra R, Ding K, Chinnaiyan AM
Cell reports. Medicine 2024 Oct 15;5(10):101752
Cell reports. Medicine 2024 Oct 15;5(10):101752
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
Zhang R, Hu M, Liu Y, Li W, Xu Z, He S, Lu Y, Gong Y, Wang X, Hai S, Li S, Qi S, Li Y, Shu Y, Du D, Zhang H, Xu H, Zhou Z, Lei P, Chen HN, Dai L
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
Chiral Hydrogel Nerve Conduit Boosts Peripheral Nerve Regeneration via Regulation of Schwann Cell Reprogramming.
Han S, Gao L, Dou X, Wang Z, Yang K, Li D, Yuan Y, Xing C, Jiang B, Tian Y, Feng CL, Zhang P
ACS nano 2024 Oct 15;18(41):28358-28370
ACS nano 2024 Oct 15;18(41):28358-28370
Targeting NQO1 induces ferroptosis and triggers anti-tumor immunity in immunotherapy-resistant KEAP1-deficient cancers.
Yuan Z, Wang X, Qin B, Hu R, Miao R, Zhou Y, Wang L, Liu T
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Nov;77:101160
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Nov;77:101160
PARD6A promotes lung adenocarcinoma cell proliferation and invasion through Serpina3.
Hu L, Liu M, Tang B, Li X, Xu H, Wang H, Wang D, Liu S, Xu C
Cancer gene therapy 2024 Nov;31(11):1696-1707
Cancer gene therapy 2024 Nov;31(11):1696-1707
METTL3 facilitates kidney injury through promoting IRF4-mediated plasma cell infiltration via an m6A-dependent manner in systemic lupus erythematosus.
Liu Y, Wang X, Huang M, Luo A, Liu S, Cai M, Li W, Yuan S, Zheng Z, Liu X, Tang C
BMC medicine 2024 Nov 5;22(1):511
BMC medicine 2024 Nov 5;22(1):511
Multi-protomics analysis identified host cellular pathways perturbed by tick-borne encephalitis virus infection.
Sui L, Wang W, Guo X, Zhao Y, Tian T, Zhang J, Wang H, Xu Y, Chi H, Xie H, Xu W, Liu N, Zhao L, Song G, Wang Z, Zhang K, Che L, Zhao Y, Wang G, Liu Q
Nature communications 2024 Nov 30;15(1):10435
Nature communications 2024 Nov 30;15(1):10435
An interaction network of inner centriole proteins organised by POC1A-POC1B heterodimer crosslinks ensures centriolar integrity.
Sala C, Würtz M, Atorino ES, Neuner A, Partscht P, Hoffmann T, Eustermann S, Schiebel E
Nature communications 2024 Nov 14;15(1):9857
Nature communications 2024 Nov 14;15(1):9857
Alkenyl oxindole is a novel PROTAC moiety that recruits the CRL4DCAF11 E3 ubiquitin ligase complex for targeted protein degradation.
Wang Y, Wei T, Zhao M, Huang A, Sun F, Chen L, Lin R, Xie Y, Zhang M, Xu S, Sun Z, Hong L, Wang R, Tian R, Li G
PLoS biology 2024 May;22(5):e3002550
PLoS biology 2024 May;22(5):e3002550
A Zinc Oxide Nanowire-Modified Mineralized Collagen Scaffold Promotes Infectious Bone Regeneration.
Zhang Y, Li Z, Guo B, Wang Q, Chen L, Zhu L, Zhang T, Wang R, Li W, Luo D, Liu Y
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(19):e2309230
Small (Weinheim an der Bergstrasse, Germany) 2024 May;20(19):e2309230
Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration.
Zhang JJ, Li X, Tian Y, Zou JK, Gan D, Deng DK, Jiao C, Yin Y, Tian BM, Wu RX, Chen FM, He XT
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Calbert ML, Chandramouly G, Adams CM, Saez-Ayala M, Kent T, Tyagi M, Ayyadevara VSSA, Wang Y, Krais JJ, Gordon J, Atkins J, Toma MM, Betzi S, Boghossian AS, Rees MG, Ronan MM, Roth JA, Goldman AR, Gorman N, Mitra R, Childers WE, Graña X, Skorski T, Johnson N, Hurtz C, Morelli X, Eischen CM, Pomerantz RT
Molecular cancer therapeutics 2024 May 2;23(5):683-699
Molecular cancer therapeutics 2024 May 2;23(5):683-699
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Liu M, Ren Y, Zhou Z, Yang J, Shi X, Cai Y, Arreola AX, Luo W, Fung KM, Xu C, Nipp RD, Bronze MS, Zheng L, Li YP, Houchen CW, Zhang Y, Li M
Cancer cell 2024 May 13;42(5):885-903.e4
Cancer cell 2024 May 13;42(5):885-903.e4
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Shi W, Wang J, Li Z, Xu S, Wang J, Zhang L, Yang H
Free radical biology & medicine 2024 Mar;213:343-358
Free radical biology & medicine 2024 Mar;213:343-358
Label-free cell phenotypic profiling of histamine H4R receptor and discovery of non-competitive H4R antagonist from natural products.
Tang H, Hou T, Zhou H, Liao H, Xu F, Xie X, Yuan W, Guo Z, Liu Y, Wang J, Zhou W, Liang X
Bioorganic chemistry 2024 Jun;147:107387
Bioorganic chemistry 2024 Jun;147:107387
Heparin-Functionalized Bioactive Glass to Harvest Endogenous Growth Factors for Pulp Regeneration.
Wu J, Li J, Mao S, Li B, Zhu L, Jia P, Huang G, Yang X, Xu L, Qiu D, Wang S, Dong Y
ACS applied materials & interfaces 2024 Jun 19;16(24):30715-30727
ACS applied materials & interfaces 2024 Jun 19;16(24):30715-30727
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
Chen X, Cheng G, Zhu L, Liu T, Yang X, Liu R, Ou Z, Zhang S, Tan W, Lin D, Wu C
Cell reports. Medicine 2024 Jun 18;5(6):101576
Cell reports. Medicine 2024 Jun 18;5(6):101576
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin.
Wang C, Fu W, Zhang Y, Hu X, Xu Q, Tong X
Biology direct 2024 Jun 18;19(1):47
Biology direct 2024 Jun 18;19(1):47
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
Zheng X, Wu W, Zhao Z, Zhang X, Yu S
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
METTL1-modulated LSM14A facilitates proliferation and migration in glioblastoma via the stabilization of DDX5.
Wang C, He Y, Fang X, Zhang D, Huang J, Zhao S, Li L, Li G
iScience 2024 Jul 19;27(7):110225
iScience 2024 Jul 19;27(7):110225
Glutamate rescues heat stress-induced apoptosis of Sertoli cells by enhancing the activity of antioxidant enzymes and activating the Trx1-Akt pathway in vitro.
Cai XQ, Yang H, Liang BQ, Deng CC, Xue HY, Zhang JJ, Wang XZ
Theriogenology 2024 Jul 15;223:1-10
Theriogenology 2024 Jul 15;223:1-10
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca(2+) antagonism and maintaining mitochondrial function.
Shen G, Zhou Z, Guo Y, Li L, Zeng J, Wang J, Zhao J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117192
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117192
Osteoblast Attachment on Bioactive Glass Air Particle Abrasion-Induced Calcium Phosphate Coating.
Abushahba F, Kylmäoja E, Areid N, Hupa L, Vallittu PK, Tuukkanen J, Närhi T
Bioengineering (Basel, Switzerland) 2024 Jan 12;11(1)
Bioengineering (Basel, Switzerland) 2024 Jan 12;11(1)
HBV infection effects prognosis and activates the immune response in intrahepatic cholangiocarcinoma.
Li Z, Gao Q, Wu Y, Ma X, Wu F, Luan S, Chen S, Shao S, Shen Y, Zhang D, Feng F, Yuan L, Wei S
Hepatology communications 2024 Jan 1;8(1)
Hepatology communications 2024 Jan 1;8(1)
Omega-3 polyunsaturated fatty acids and its metabolite 12-HEPE rescue busulfan disrupted spermatogenesis via target to GPR120.
Jing J, Ouyang L, Zhang H, Liang K, Ma R, Ge X, Tang T, Zhao S, Xue T, Shen J, Ma J, Li Z, Wu J, Yang Y, Zhao W, Zheng L, Qian Z, Sun S, Ge Y, Chen L, Li C, Yao B
Cell proliferation 2024 Feb;57(2):e13551
Cell proliferation 2024 Feb;57(2):e13551
Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
Wang H, Chen S, Tang Y, Nie K, Gao Y, Wang Z, Su H, Wu F, Gong J, Fang K, Dong H, Hu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155268
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155268
USP54 is a potential therapeutic target in castration-resistant prostate cancer.
Zhou C, Zhang X, Ma H, Zhou Y, Meng Y, Chen C, Shi G, Yu W, Zhang J
BMC urology 2024 Feb 6;24(1):32
BMC urology 2024 Feb 6;24(1):32
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells.
Hu H, Hu W, Guo AD, Zhai L, Ma S, Nie HJ, Zhou BS, Liu T, Jia X, Liu X, Yao X, Tan M, Chen XH
Nature communications 2024 Feb 17;15(1):1465
Nature communications 2024 Feb 17;15(1):1465
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
Arctigenin promotes mucosal healing in ulcerative colitis through facilitating focal adhesion assembly and colonic epithelial cell migration via targeting focal adhesion kinase.
Guo Y, Liu X, Tao Y, Zhu Y, Zhang J, Yu X, Guo P, Liu S, Wei Z, Dai Y, Xia Y
International immunopharmacology 2024 Feb 15;128:111552
International immunopharmacology 2024 Feb 15;128:111552
LncRNA MYOSLID contributes to PH via targeting BMPR2 signaling in pulmonary artery smooth muscle cell.
Chen Y, Li Y, Leng B, Cao C, Wu G, Ye S, Deng L
Vascular pharmacology 2024 Dec;157:107439
Vascular pharmacology 2024 Dec;157:107439
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells.
Wang Y, Zhang Y, Luo H, Wei W, Liu W, Wang W, Wu Y, Peng C, Ji Y, Zhang J, Zhu C, Bai W, Xia L, Lei H, Xu H, Yin L, Weng W, Yang L, Liu L, Zhou A, Wei Y, Zhu Q, Zhu W, Yang Y, Xu Z, Wu Y
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5235-5248
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5235-5248
CRISPR/Cas13 sgRNA-Mediated RNA-RNA Interaction Mapping in Live Cells with APOBEC RNA Editing.
Diao LT, Xie SJ, Xu WY, Zhang HH, Hou YR, Hu YX, Liang XX, Liang JB, Zhang Q, Xiao ZD
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(45):e2409004
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(45):e2409004
Scutellaria barbata D.Don and Scleromitrion diffusum (Willd.) R.J.Wang inhibits the progression of triple negative breast cancer though the activation inhibition of NF-κB triggered by CAFs-derived IL6.
Pan Y, Ma T, Chen D, Wang Y, Peng Y, Lu T, Yin X, Li H, Zhang G, Wang X
Journal of ethnopharmacology 2024 Dec 5;335:118656
Journal of ethnopharmacology 2024 Dec 5;335:118656
Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation.
Xu Y, Cai Q, Zhao C, Zhang W, Xu X, Lin H, Lin Y, Chen D, Lin S, Jia P, Wang M, Zhang L, Lin W
Pharmaceuticals (Basel, Switzerland) 2024 Dec 25;18(1)
Pharmaceuticals (Basel, Switzerland) 2024 Dec 25;18(1)
Mitochondrial transplantation rescues Ca(2+) homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy.
Li S, Zhang J, Fu W, Cao J, Li Z, Tian X, Yang M, Zhao J, Wang C, Liu Y, Liu M, Zhao X, Li X, Dong J, Qi Y
Cell reports 2024 Dec 24;43(12):115065
Cell reports 2024 Dec 24;43(12):115065
H(2)S-releasing oridonin derivatives with improved antitumor activity by inhibiting the PI3K/AKT pathway.
Li H, Ma Q, Jia Y, Wang C, Wu J, Wang S, Hua H, Lu J, Li D
Bioorganic & medicinal chemistry 2024 Dec 1;115:117968
Bioorganic & medicinal chemistry 2024 Dec 1;115:117968
Polydatin, a potential NOX5 agonist, synergistically enhances antitumor activity of cisplatin by stimulating oxidative stress in non‑small cell lung cancer.
Wu S, Zhao Q, Liu S, Kuang J, Zhang J, Onga A, Shen Y, Wang J, Sui H, Ni L, Ye Y, Tu X, Le HB, Zheng Y, Cui R, Zhu W
International journal of oncology 2024 Aug;65(2)
International journal of oncology 2024 Aug;65(2)
Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.
Qin C, Zhao B, Wang Y, Li Z, Li T, Zhao Y, Wang W, Zhao Y
Journal of extracellular vesicles 2024 Aug;13(8):e12488
Journal of extracellular vesicles 2024 Aug;13(8):e12488
Triptolide-induced cuproptosis is a novel antitumor strategy for the treatment of cervical cancer.
Xiao Y, Yin J, Liu P, Zhang X, Lin Y, Guo J
Cellular & molecular biology letters 2024 Aug 28;29(1):113
Cellular & molecular biology letters 2024 Aug 28;29(1):113
Mito-LND and (E)-Akt inhibitor-IV: novel compounds inducing endoplasmic reticulum stress and ROS accumulation against hepatocellular carcinoma.
Liao S, Wang Q, Chen S, Huang Q, Zhou L, Liu H, He S, Zhou Z
Journal of translational medicine 2024 Aug 28;22(1):792
Journal of translational medicine 2024 Aug 28;22(1):792
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Deng J, Lin X, Qin J, Li Q, Zhang Y, Zhang Q, Ji C, Shen S, Li Y, Zhang B, Lin N
Redox biology 2024 Apr;70:103039
Redox biology 2024 Apr;70:103039
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
Li ZA, Bajpai AK, Wang R, Liu Y, Webby RJ, Wilk E, Gu W, Schughart K, Li K, Lu L
Virus research 2024 Apr;342:199335
Virus research 2024 Apr;342:199335
Integrative analysis unveils ECM signatures and pathways driving hepatocellular carcinoma progression: A multi-omics approach and prognostic model development.
Liu Z, Zhao P
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
Journal of cellular and molecular medicine 2024 Apr;28(8):e18230
RBMS1 Coordinates with the m(6)A Reader YTHDF1 to Promote NSCLC Metastasis through Stimulating S100P Translation.
Sun Y, Chen D, Sun S, Ren M, Zhou L, Chen C, Zhao J, Wei H, Zhao Q, Qi Y, Zhang J, Zhang G, Liu H, Yang Q, Liu Q, Wang Y, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2307122
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2307122
A NRF2 Regulated and the Immunosuppressive Microenvironment Reversed Nanoplatform for Cholangiocarcinoma Photodynamic-Gas Therapy.
Wang W, Gao Y, Xu J, Zou T, Yang B, Hu S, Cheng X, Xia Y, Zheng Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307143
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307143
Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides.
Schofield JH, Longo J, Sheldon RD, Albano E, Ellis AE, Hawk MA, Murphy S, Duong L, Rahmy S, Lu X, Jones RG, Schafer ZT
Cell reports 2024 Apr 23;43(4):113984
Cell reports 2024 Apr 23;43(4):113984
Fatty liver disease protective MTARC1 p.A165T variant reduces the protein stability of MTARC1.
Wu M, Tie M, Hu L, Yang Y, Chen Y, Ferguson D, Chen Y, He A
Biochemical and biophysical research communications 2024 Apr 2;702:149655
Biochemical and biophysical research communications 2024 Apr 2;702:149655
Sea Buckthorn Polyphenols Alleviate High-Fat-Diet-Induced Metabolic Disorders in Mice via Reprograming Hepatic Lipid Homeostasis Owing to Directly Targeting Fatty Acid Synthase.
Yuan L, Zhang W, Fang W, Zhuang X, Gong W, Xu X, Li Y, Wang X
Journal of agricultural and food chemistry 2024 Apr 17;72(15):8632-8649
Journal of agricultural and food chemistry 2024 Apr 17;72(15):8632-8649
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Tang X, Luo X, Wang X, Zhang Y, Xie J, Niu X, Lu X, Deng X, Xu Z, Wu F
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Diagnostic Values of METTL1-Related Genes and Immune Characteristics in Systemic Lupus Erythematosus.
Liu Y, Zhu E, Lei Y, Luo A, Yan Y, Cai M, Liu S, Huang Y, Guan H, Zhong M, Li W, Lin L, Hultstöm M, Lai E, Zheng Z, Liu X, Tang C
Journal of inflammation research 2023;16:5367-5383
Journal of inflammation research 2023;16:5367-5383
Prognostic and therapeutic implications of iron-related cell death pathways in acute myeloid leukemia.
Li T, Lin T, Zhu J, Zhou M, Fan S, Zhou H, Mu Q, Sheng L, Ouyang G
Frontiers in oncology 2023;13:1222098
Frontiers in oncology 2023;13:1222098
Role of UDP-glucose ceramide glucosyltransferase in venous malformation.
Chen S, Wang Y, Kong L, Ji Y, Cui J, Shen W
Frontiers in cell and developmental biology 2023;11:1178045
Frontiers in cell and developmental biology 2023;11:1178045
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Lin X, Liu YH, Zhang HQ, Wu LW, Li Q, Deng J, Zhang Q, Yang Y, Zhang C, Li YL, Hu J
Cancer cell international 2023 Sep 23;23(1):208
Cancer cell international 2023 Sep 23;23(1):208
Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides.
Schofield JH, Longo J, Sheldon RD, Albano E, Hawk MA, Murphy S, Duong L, Rahmy S, Lu X, Jones RG, Schafer ZT
bioRxiv : the preprint server for biology 2023 Sep 17;
bioRxiv : the preprint server for biology 2023 Sep 17;
Predicting lung adenocarcinoma prognosis, immune escape, and pharmacomic profile from arginine and proline-related genes.
Wang Z, Zhang J, Shi S, Ma H, Wang D, Zuo C, Zhang Q, Lian C
Scientific reports 2023 Sep 14;13(1):15198
Scientific reports 2023 Sep 14;13(1):15198
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells.
Liu Y, Yao X, Zhao Y, Fang D, Shi L, Yang L, Song G, Cai K, Li L, Deng Q, Li M, Luo Z
Cell reports 2023 Oct 31;42(10):113213
Cell reports 2023 Oct 31;42(10):113213
In Cerebellar Atrophy of 12-Month-Old ATM-Null Mice, Transcriptome Upregulations Concern Most Neurotransmission and Neuropeptide Pathways, While Downregulations Affect Prominently Itpr1, Usp2 and Non-Coding RNA.
Reichlmeir M, Canet-Pons J, Koepf G, Nurieva W, Duecker RP, Doering C, Abell K, Key J, Stokes MP, Zielen S, Schubert R, Ivics Z, Auburger G
Cells 2023 Oct 3;12(19)
Cells 2023 Oct 3;12(19)
Regorafenib activates oxidative stress by inhibiting SELENOS and potentiates oxaliplatin-induced cell death in colon cancer cells.
Yu Y, Wu T, Zhang X, Li P, Ye L, Kuang J, Tao L, Ni L, Zhao Q, Zhang J, Pan H, Xie C, Zheng C, Li S, Cui R
European journal of pharmacology 2023 Oct 15;957:175986
European journal of pharmacology 2023 Oct 15;957:175986
An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing.
Pan H, Cheng X, Rodríguez PFG, Zhang X, Chung I, Jin VX, Li W, Hu Y, Li R
The Journal of biological chemistry 2023 Nov;299(11):105259
The Journal of biological chemistry 2023 Nov;299(11):105259
Multiomics characterization and verification of clear cell renal cell carcinoma molecular subtypes to guide precise chemotherapy and immunotherapy.
Meng J, Jiang A, Lu X, Gu D, Ge Q, Bai S, Zhou Y, Zhou J, Hao Z, Yan F, Wang L, Wang H, Du J, Liang C
iMeta 2023 Nov;2(4):e147
iMeta 2023 Nov;2(4):e147
p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP.
Huang Y, Xiong C, Wang C, Deng J, Zuo Z, Wu H, Xiong J, Wu X, Lu H, Hao Q, Zhou X
Cell reports 2023 Nov 28;42(11):113426
Cell reports 2023 Nov 28;42(11):113426
Nanofibrous PCL-Based Human Trabecular Meshwork for Aqueous Humor Outflow Studies.
Bikuna-Izagirre M, Aldazabal J, Extramiana L, Moreno-Montañés J, Carnero E, Paredes J
ACS biomaterials science & engineering 2023 Nov 13;9(11):6333-6344
ACS biomaterials science & engineering 2023 Nov 13;9(11):6333-6344
Osteocyte β3 integrin promotes bone mass accrual and force-induced bone formation in mice.
Qin L, Chen Z, Yang D, He T, Xu Z, Zhang P, Chen D, Yi W, Xiao G
Journal of orthopaedic translation 2023 May;40:58-71
Journal of orthopaedic translation 2023 May;40:58-71
Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis.
Wang X, Wei X, Lu Y, Wang Q, Fu R, Wang Y, Wang Q, Wang X, Chen S, Xu A, Yuan S
PLoS biology 2023 May;21(5):e3002062
PLoS biology 2023 May;21(5):e3002062
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Apiz Saab JJ, Dzierozynski LN, Jonker PB, AminiTabrizi R, Shah H, Menjivar RE, Scott AJ, Nwosu ZC, Zhu Z, Chen RN, Oh M, Sheehan C, Wahl DR, Pasca di Magliano M, Lyssiotis CA, Macleod KF, Weber CR, Muir A
eLife 2023 May 31;12
eLife 2023 May 31;12
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice.
Kessel JC, Weiskirchen R, Schröder SK
International journal of molecular sciences 2023 May 25;24(11)
International journal of molecular sciences 2023 May 25;24(11)
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Wang YN, Yu L, Wang T, Liu S
International journal of biological macromolecules 2023 May 1;236:123998
International journal of biological macromolecules 2023 May 1;236:123998
Myb Repression Mediates Stat5b-knockdown-induced Apoptosis and Inhibits Proliferation of Glioblastoma Stem Cells.
Moyama C, Fujita M, Okamoto H, Ii H, Nakata S
Cancer genomics & proteomics 2023 Mar-Apr;20(2):195-202
Cancer genomics & proteomics 2023 Mar-Apr;20(2):195-202
Bioinspired Piezoelectric Periosteum to Augment Bone Regeneration via Synergistic Immunomodulation and Osteogenesis.
Liu H, Shi Y, Zhu Y, Wu P, Deng Z, Dong Q, Wu M, Cai L
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
ACS applied materials & interfaces 2023 Mar 8;15(9):12273-12293
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
Xue T, Zhao S, Zhang H, Tang T, Zheng L, Jing J, Ge X, Ma R, Ma J, Ren X, Jueraitetibaike K, Guo Z, Chen L, Yao B
iScience 2023 Mar 17;26(3):106131
iScience 2023 Mar 17;26(3):106131
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Qin C, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cell death & disease 2023 Mar 11;14(3):191
Cell death & disease 2023 Mar 11;14(3):191
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
Suryawan A, Rudar M, Naberhuis JK, Fiorotto ML, Davis TA
Pediatric research 2023 Jun;93(7):1891-1898
Pediatric research 2023 Jun;93(7):1891-1898
In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
Jin ML, Gong Y, Ji P, Hu X, Shao ZM
Cancer science 2023 Jun;114(6):2375-2385
Cancer science 2023 Jun;114(6):2375-2385
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities.
Debar L, Ishak L, Moretton A, Anoosheh S, Morel F, Jenninger L, Garreau-Balandier I, Vernet P, Hofer A, van den Wildenberg S, Farge G
Mitochondrion 2023 Jul;71:93-103
Mitochondrion 2023 Jul;71:93-103
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells.
Hom LM, Sun S, Campbell J, Liu P, Culbert S, Murphy IM, Schafer ZT
The Journal of biological chemistry 2023 Jul;299(7):104922
The Journal of biological chemistry 2023 Jul;299(7):104922
Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33.
Witz A, Effertz D, Goebel N, Schwab M, Franke UFW, Torzewski M
Biomolecules 2023 Jul 7;13(7)
Biomolecules 2023 Jul 7;13(7)
Identification of c-Met as a novel target of γ-glutamylcyclotransferase.
Saito Y, Taniguchi K, Ii H, Horinaka M, Kageyama S, Nakata S, Ukimura O, Sakai T
Scientific reports 2023 Jul 24;13(1):11922
Scientific reports 2023 Jul 24;13(1):11922
Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells.
Flores JC, Sidoli S, Dawlaty MM
iScience 2023 Jul 21;26(7):107170
iScience 2023 Jul 21;26(7):107170
Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1.
Bagka M, Choi H, Héritier M, Schwaemmle H, Pasquer QTL, Braun SMG, Scapozza L, Wu Y, Hoogendoorn S
Nature communications 2023 Jul 1;14(1):3893
Nature communications 2023 Jul 1;14(1):3893
Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression.
Hu Z, Wei F, Su Y, Wang Y, Shen Y, Fang Y, Ding J, Chen Y
Signal transduction and targeted therapy 2023 Jan 6;8(1):11
Signal transduction and targeted therapy 2023 Jan 6;8(1):11
Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury.
Ren J, Zhu B, Gu G, Zhang W, Li J, Wang H, Wang M, Song X, Wei Z, Feng S
Cell death & disease 2023 Jan 30;14(1):70
Cell death & disease 2023 Jan 30;14(1):70
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Jiang Z, Jiang Y, Fan J, Zhang J, Xu G, Fan Y, Zhang L, Qin X, Jiang X, Mao L, Liu G, Chen C, Zou Z
Toxicology letters 2023 Jan 15;373:62-75
Toxicology letters 2023 Jan 15;373:62-75
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury.
Huo S, Wang Q, Shi W, Peng L, Jiang Y, Zhu M, Guo J, Peng D, Wang M, Men L, Huang B, Lv J, Lin L
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
RBM4 regulates cellular senescence via miR1244/SERPINE1 axis.
Wang L, Zhang X, Sheng J, Chen L, Zhi L, Zheng Q, Qi Y, Wang L, Zhang J, Zhao J, Wang Y, Liu SX, Sun MZ, Zhang W
Cell death & disease 2023 Jan 13;14(1):27
Cell death & disease 2023 Jan 13;14(1):27
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
Liu D, Liang CH, Huang B, Zhuang X, Cui W, Yang L, Yang Y, Zhang Y, Fu X, Zhang X, Du L, Gu W, Wang X, Yin C, Chai R, Chu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2204006
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2204006
GEF-H1 Transduces FcεRI Signaling in Mast Cells to Activate RhoA and Focal Adhesion Formation during Exocytosis.
Guo Y, Negre J, Eitzen G
Cells 2023 Feb 7;12(4)
Cells 2023 Feb 7;12(4)
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Gu G, Zhu B, Ren J, Song X, Fan B, Ding H, Shang J, Wu H, Li J, Wang H, Li J, Wei Z, Feng S
Cell & bioscience 2023 Feb 4;13(1):23
Cell & bioscience 2023 Feb 4;13(1):23
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells.
Hom LM, Sun S, Campbell J, Liu P, Culbert S, Murphy IM, Schafer ZT
bioRxiv : the preprint server for biology 2023 Feb 22;
bioRxiv : the preprint server for biology 2023 Feb 22;
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Perinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner.
Noble RMN, Holody CD, Woodman AG, Nie C, Liu SN, Young D, Wiedemeyer A, Soni S, Dyck JRB, Graf D, Eckersley LG, Dufour A, Bourque SL
Clinical science (London, England : 1979) 2023 Aug 14;137(15):1115-1130
Clinical science (London, England : 1979) 2023 Aug 14;137(15):1115-1130
A subset of VEGFR-TKIs activates AMPK in LKB1-mutant lung cancer.
Yang L, Zhang Q, Xiong Y, Dang Z, Xiao H, Chen Q, Dai X, Zhang L, Zhu J, Wang D, Li M
Cancer science 2023 Apr;114(4):1651-1662
Cancer science 2023 Apr;114(4):1651-1662
Klotho protects chromosomal DNA from radiation-induced damage.
Nakayama S, Sun J, Horikoshi Y, Kamimura Y, Ike T, Fujino S, Kinugasa Y, Sasaki K, Nakashima A, Masaki T, Tashiro S
Journal of biochemistry 2023 Apr 26;173(5):375-382
Journal of biochemistry 2023 Apr 26;173(5):375-382
RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.
Chen L, Zhang W, Chen D, Yang Q, Sun S, Dai Z, Li Z, Liang X, Chen C, Jiao Y, Zhi L, Zhao L, Zhang J, Liu X, Zhao J, Li M, Wang Y, Qi Y
Signal transduction and targeted therapy 2023 Apr 21;8(1):159
Signal transduction and targeted therapy 2023 Apr 21;8(1):159
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Biophysical Analysis and Preclinical Pharmacokinetics-Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute.
Greenfield A, Lamb DR, Gu X, Thangaraju K, Setua S, Yahya A, Vahedi A, Khan MA, Wang Q, Buehler PW, Palmer AF
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Biomacromolecules 2023 Apr 10;24(4):1855-1870
Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mTOR pathway.
Wang L, Otkur W, Wang A, Wang W, Lyu Y, Fang L, Shan X, Song M, Feng Y, Zhao Y, Piao HL, Qi H, Liu JW
Frontiers in pharmacology 2022;13:906043
Frontiers in pharmacology 2022;13:906043
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
Wang C, Wang Y, Fu Z, Huang W, Yu Z, Wang J, Zheng K, Zhang S, Li S, Chen J
Frontiers in oncology 2022;12:837581
Frontiers in oncology 2022;12:837581
Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling.
Mahapatra S, Sharma MVR, Brownson B, Gallicano VE, Gallicano GI
Molecular biology of the cell 2022 Sep 15;33(11):ar96
Molecular biology of the cell 2022 Sep 15;33(11):ar96
Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice.
Zhang Y, Xi X, Yu H, Yang L, Lin J, Yang W, Liu J, Fan X, Xu Y
Molecular therapy. Nucleic acids 2022 Sep 13;29:657-671
Molecular therapy. Nucleic acids 2022 Sep 13;29:657-671
Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility.
Hou M, Zhu L, Jiang J, Liu Z, Li Z, Jia W, Hu J, Zhou X, Zhang D, Luo Y, Peng X, Xi Q, Jin L, Zhang X
Reproductive sciences (Thousand Oaks, Calif.) 2022 Oct;29(10):3047-3054
Reproductive sciences (Thousand Oaks, Calif.) 2022 Oct;29(10):3047-3054
Oxidant stress-sensitive circRNA Mdc1 controls cardiomyocyte chromosome stability and cell cycle re-entry during heart regeneration.
Ma W, Wang X, Sun H, Xu B, Song R, Tian Y, Zhao L, Xu Y, Zhao Y, Yang F, Chen H, Gong R, Yu Y, Li X, Li S, Zhang W, Zhang T, Ne J, Cai B
Pharmacological research 2022 Oct;184:106422
Pharmacological research 2022 Oct;184:106422
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency.
Oluwadare J, Cabodevilla AG, Son NH, Hu Y, Mullick AE, Verano M, Alemán JO, Ramasamy R, Goldberg IJ
Journal of lipid research 2022 Nov;63(11):100274
Journal of lipid research 2022 Nov;63(11):100274
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
Zhang J, Zhang G, Zhang W, Bai L, Wang L, Li T, Yan L, Xu Y, Chen D, Gao W, Gao C, Chen C, Ren M, Jiao Y, Qin H, Sun Y, Zhi L, Qi Y, Zhao J, Liu Q, Liu H, Wang Y
Cell death and differentiation 2022 Nov;29(11):2247-2261
Cell death and differentiation 2022 Nov;29(11):2247-2261
Antifouling poly(PEGMA) grafting modified titanium surface reduces osseointegration through resisting adhesion of bone marrow mesenchymal stem cells.
Huang T, Tu C, Zhou T, Yu Z, Wang Y, Yu Q, Yu K, Jiang Z, Gao C, Yang G
Acta biomaterialia 2022 Nov;153:585-595
Acta biomaterialia 2022 Nov;153:585-595
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Qin C, Li T, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cancer cell international 2022 Nov 7;22(1):340
Cancer cell international 2022 Nov 7;22(1):340
Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development.
Wang S, Hao Q, Li J, Chen Y, Lu H, Wu X, Zhou X
Genes & diseases 2022 May;9(3):705-716
Genes & diseases 2022 May;9(3):705-716
Induction of Stem-Cell-Derived Cardiomyogenesis by Fibroblast Growth Factor 10 (FGF10) and Its Interplay with Cardiotrophin-1 (CT-1).
Khosravi F, Ahmadvand N, Wartenberg M, Sauer H
Biology 2022 Mar 30;11(4)
Biology 2022 Mar 30;11(4)
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification.
Choezom D, Gross JC
Journal of cell science 2022 Mar 1;135(5)
Journal of cell science 2022 Mar 1;135(5)
Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the presence of lipopolysaccharide.
Li L, Sun W, Yu J, Lei W, Zeng H, Shi B
Journal of periodontal research 2022 Jun;57(3):644-659
Journal of periodontal research 2022 Jun;57(3):644-659
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Zhang L, Zhang Y, Qin X, Jiang X, Zhang J, Mao L, Jiang Z, Jiang Y, Liu G, Qiu J, Chen C, Qiu F, Zou Z
Critical care (London, England) 2022 Jun 9;26(1):171
Critical care (London, England) 2022 Jun 9;26(1):171
Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function.
Zhao X, Wei Y, Chu YY, Li Y, Hsu JM, Jiang Z, Liu C, Hsu JL, Chang WC, Yang R, Chan LC, Qu J, Zhang S, Ying H, Yu D, Hung MC
Cancer research 2022 Jun 6;82(11):2185-2195
Cancer research 2022 Jun 6;82(11):2185-2195
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL
Cell reports 2022 Jun 21;39(12):110995
Cell reports 2022 Jun 21;39(12):110995
JCI‑20679 suppresses the proliferation of glioblastoma stem cells by activating AMPK and decreasing NFATc2 expression levels.
Ando S, Kojima N, Moyama C, Fujita M, Ohta K, Ii H, Nakata S
Molecular medicine reports 2022 Jul;26(1)
Molecular medicine reports 2022 Jul;26(1)
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Yao Q, Wang H, Chen H, Li Z, Jiang Y, Li Z, Wang J, Xing Y, Liu F, Yu D, Yin S
Molecular neurobiology 2022 Jan;59(1):386-404
Molecular neurobiology 2022 Jan;59(1):386-404
γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis.
Taniguchi K, Kageyama S, Moyama C, Ando S, Ii H, Ashihara E, Horinaka M, Sakai T, Kubota S, Kawauchi A, Nakata S
Cancer gene therapy 2022 Jan;29(1):37-48
Cancer gene therapy 2022 Jan;29(1):37-48
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71
The American journal of pathology 2022 Jan;192(1):56-71
Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus.
Seki M, Komuro A, Ishikawa T, Takahashi M, Nashimoto M
Biochemical and biophysical research communications 2022 Jan 8;587:63-68
Biochemical and biophysical research communications 2022 Jan 8;587:63-68
Five hypoxia and immunity related genes as potential biomarkers for the prognosis of osteosarcoma.
Liu D, Hu Z, Jiang J, Zhang J, Hu C, Huang J, Wei Q
Scientific reports 2022 Jan 31;12(1):1617
Scientific reports 2022 Jan 31;12(1):1617
Modular assembly of the principal microtubule nucleator γ-TuRC.
Würtz M, Zupa E, Atorino ES, Neuner A, Böhler A, Rahadian AS, Vermeulen BJA, Tonon G, Eustermann S, Schiebel E, Pfeffer S
Nature communications 2022 Jan 25;13(1):473
Nature communications 2022 Jan 25;13(1):473
The osteogenic effects of porous Tantalum and Titanium alloy scaffolds with different unit cell structure.
Huang G, Pan ST, Qiu JX
Colloids and surfaces. B, Biointerfaces 2022 Feb;210:112229
Colloids and surfaces. B, Biointerfaces 2022 Feb;210:112229
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes.
Li Y, Yang L, Hou Y, Zhang Z, Chen M, Wang M, Liu J, Wang J, Zhao Z, Xie C, Lu X
Bioactive materials 2022 Dec;18:213-227
Bioactive materials 2022 Dec;18:213-227
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Lu B, Chen X, Liu X, Chen J, Qin H, Chen S, Zhao Y
Journal of translational medicine 2022 Dec 24;20(1):618
Journal of translational medicine 2022 Dec 24;20(1):618
Dihydroartemisinin enhances the anti-tumor activity of oxaliplatin in colorectal cancer cells by altering PRDX2-reactive oxygen species-mediated multiple signaling pathways.
Yu Y, Chen D, Wu T, Lin H, Ni L, Sui H, Xiao S, Wang C, Jiang S, Pan H, Li S, Jin X, Xie C, Cui R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153932
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153932
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Cao DY, Zhang ZH, Li RZ, Shi XK, Xi RY, Zhang GL, Li F, Wang F
Immunology letters 2022 Apr;244:28-39
Immunology letters 2022 Apr;244:28-39
Fibrous Structure and Stiffness of Designer Protein Hydrogels Synergize to Regulate Endothelial Differentiation of Bone Marrow Mesenchymal Stem Cells.
Tian KK, Huang SC, Xia XX, Qian ZG
Biomacromolecules 2022 Apr 11;23(4):1777-1788
Biomacromolecules 2022 Apr 11;23(4):1777-1788
Three-Dimensionally Printed Ti2448 With Low Stiffness Enhanced Angiogenesis and Osteogenesis by Regulating Macrophage Polarization via Piezo1/YAP Signaling Axis.
Tang Z, Wei X, Li T, Wu H, Xiao X, Hao Y, Li S, Hou W, Shi L, Li X, Guo Z
Frontiers in cell and developmental biology 2021;9:750948
Frontiers in cell and developmental biology 2021;9:750948
The Recurrent Mutation in PATL2 Inhibits Its Degradation Thus Causing Female Infertility Characterized by Oocyte Maturation Defect Through Regulation of the Mos-MAPK Pathway.
Cao Q, Zhao C, Wang C, Cai L, Xia M, Zhang X, Han J, Xu Y, Zhang J, Ling X, Ma X, Huo R
Frontiers in cell and developmental biology 2021;9:628649
Frontiers in cell and developmental biology 2021;9:628649
The forkhead box transcription factor FoxP4 regulates thermogenic programs in adipocytes.
Perie L, Verma N, Mueller E
Journal of lipid research 2021;62:100102
Journal of lipid research 2021;62:100102
BRCA1 Antibodies Matter.
Yang J, Qi L, Chiang HC, Yuan B, Li R, Hu Y
International journal of biological sciences 2021;17(12):3239-3254
International journal of biological sciences 2021;17(12):3239-3254
Inhibition of Shear-Induced Platelet Aggregation by Xueshuantong via Targeting Piezo1 Channel-Mediated Ca(2+) Signaling Pathway.
Liu L, Zhang Q, Xiao S, Sun Z, Ding S, Chen Y, Wang L, Yin X, Liao F, Jiang LH, Xue M, You Y
Frontiers in pharmacology 2021;12:606245
Frontiers in pharmacology 2021;12:606245
SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway.
Luo Z, Wang J, Zhu Y, Sun X, He C, Cai M, Ma J, Wang Y, Han S
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Neoplasia (New York, N.Y.) 2021 Oct;23(10):1037-1047
Browning of adipose tissue and increased thermogenesis induced by Methotrexate.
Verma N, Perie L, Corciulo C, Leucht P, Ramkhelawon B, Cronstein BN, Mueller E
FASEB bioAdvances 2021 Nov;3(11):877-887
FASEB bioAdvances 2021 Nov;3(11):877-887
Disorganization of intercalated discs in dilated cardiomyopathy.
Ito Y, Yoshida M, Masuda H, Maeda D, Kudo-Asabe Y, Umakoshi M, Nanjo H, Goto A
Scientific reports 2021 Jun 4;11(1):11852
Scientific reports 2021 Jun 4;11(1):11852
The molecular basis of coupling between poly(A)-tail length and translational efficiency.
Xiang K, Bartel DP
eLife 2021 Jul 2;10
eLife 2021 Jul 2;10
Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling.
Inaba H, Miao Q, Nakata T
The Journal of biological chemistry 2021 Jan-Jun;296:100290
The Journal of biological chemistry 2021 Jan-Jun;296:100290
SPEG binds with desmin and its deficiency causes defects in triad and focal adhesion proteins.
Luo S, Li Q, Lin J, Murphy Q, Marty I, Zhang Y, Kazerounian S, Agrawal PB
Human molecular genetics 2021 Feb 25;29(24):3882-3891
Human molecular genetics 2021 Feb 25;29(24):3882-3891
Inhibition of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model.
Tanigawa S, Fujita M, Moyama C, Ando S, Ii H, Kojima Y, Fujishita T, Aoki M, Takeuchi H, Yamanaka T, Takahashi Y, Hashimoto N, Nakata S
Cancer gene therapy 2021 Dec;28(12):1339-1352
Cancer gene therapy 2021 Dec;28(12):1339-1352
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis.
Cui W, Liu D, Gu W, Chu B
Cell death and differentiation 2021 Aug;28(8):2536-2551
Cell death and differentiation 2021 Aug;28(8):2536-2551
DDX52 knockdown inhibits the growth of prostate cancer cells by regulating c-Myc signaling.
Yu W, Ma H, Li J, Ge J, Wang P, Zhou Y, Zhang J, Shi G
Cancer cell international 2021 Aug 16;21(1):430
Cancer cell international 2021 Aug 16;21(1):430
Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, Asahina N, Shiraishi H, Hosoki K, Tomiwa K, Ishihara N, Mishima H, Mori R, Nakashima M, Saitoh S, Yoshiura KI
Development (Cambridge, England) 2021 Aug 15;148(16)
Development (Cambridge, England) 2021 Aug 15;148(16)
Reduced intracellular chloride concentration impairs angiogenesis by inhibiting oxidative stress-mediated VEGFR2 activation.
Li K, Liu YY, Lv XF, Lin ZM, Zhang TT, Zhang FR, Guo JW, Hong Y, Liu X, Lin XC, Zhou JG, Wu QQ, Liang SJ, Shang JY
Acta pharmacologica Sinica 2021 Apr;42(4):560-572
Acta pharmacologica Sinica 2021 Apr;42(4):560-572
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.
Afonso MS, Verma N, van Solingen C, Cyr Y, Sharma M, Perie L, Corr EM, Schlegel M, Shanley LC, Peled D, Yoo JY, Schmidt AM, Mueller E, Moore KJ
Arteriosclerosis, thrombosis, and vascular biology 2021 Apr;41(4):1360-1373
Arteriosclerosis, thrombosis, and vascular biology 2021 Apr;41(4):1360-1373
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
Chiang MH, Liang CJ, Lin LC, Yang YF, Huang CC, Chen YH, Kao HL, Chen YC, Ke SR, Lee CW, Lin MS, Chen YL
Journal of cellular physiology 2020 Sep;235(9):6085-6102
Journal of cellular physiology 2020 Sep;235(9):6085-6102
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
Xu R, Jones W, Wilcz-Villega E, Costa AS, Rajeeve V, Bentham RB, Bryson K, Nagano A, Yaman B, Olendo Barasa S, Wang Y, Chelala C, Cutillas P, Szabadkai G, Frezza C, Bianchi K
EMBO reports 2020 Sep 3;21(9):e48260
EMBO reports 2020 Sep 3;21(9):e48260
Oscillating Magnetic Field Regulates Cell Adherence and Endothelialization Based on Magnetic Nanoparticle-Modified Bacterial Cellulose.
Zhang L, Wei F, Bai Q, Song D, Zheng Z, Wang Y, Liu X, Abdulrahman AA, Bian Y, Xu X, Chen C, Zhang H, Sun D
ACS applied materials & interfaces 2020 Nov 25;12(47):52467-52478
ACS applied materials & interfaces 2020 Nov 25;12(47):52467-52478
The mRNA levels of heat shock factor 1 are regulated by thermogenic signals via the cAMP-dependent transcription factor ATF3.
Verma N, Perie L, Mueller E
The Journal of biological chemistry 2020 May 1;295(18):5984-5994
The Journal of biological chemistry 2020 May 1;295(18):5984-5994
ETS variant transcription factor 5 and c-Myc cooperate in derepressing the human telomerase gene promoter via composite ETS/E-box motifs.
Zhang F, Wang S, Zhu J
The Journal of biological chemistry 2020 Jul 17;295(29):10062-10075
The Journal of biological chemistry 2020 Jul 17;295(29):10062-10075
HNF1B inhibits cell proliferation via repression of SMAD6 expression in prostate cancer.
Lu W, Sun J, Zhou H, Wang F, Zhao C, Li K, Fan C, Ding G, Wang J
Journal of cellular and molecular medicine 2020 Dec;24(24):14539-14548
Journal of cellular and molecular medicine 2020 Dec;24(24):14539-14548
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
Tran DT, Pottekat A, Mir SA, Loguercio S, Jang I, Campos AR, Scully KM, Lahmy R, Liu M, Arvan P, Balch WE, Kaufman RJ, Itkin-Ansari P
Diabetes 2020 Aug;69(8):1723-1734
Diabetes 2020 Aug;69(8):1723-1734
Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.
Cao Q, Zhao C, Zhang X, Zhang H, Lu Q, Wang C, Hu Y, Ling X, Zhang J, Huo R
Journal of cellular and molecular medicine 2020 Aug;24(15):8557-8566
Journal of cellular and molecular medicine 2020 Aug;24(15):8557-8566
Regulation of hepatic glutamine metabolism by miR-122.
Sengupta D, Cassel T, Teng KY, Aljuhani M, Chowdhary VK, Hu P, Zhang X, Fan TW, Ghoshal K
Molecular metabolism 2020 Apr;34:174-186
Molecular metabolism 2020 Apr;34:174-186
Long noncoding RNA expression analysis reveals the regulatory effects of nitinol-based nanotubular coatings on human coronary artery endothelial cells.
Shang P, Chen G, Zu G, Song X, Jiao P, You G, Zhao J, Li H, Zhou H
International journal of nanomedicine 2019;14:3297-3309
International journal of nanomedicine 2019;14:3297-3309
Micro- and Nanohemispherical 3D Imprints Modulate the Osteogenic Differentiation and Mineralization Tendency of Bone Cells.
Zhu Y, Liu X, Wu J, Wong TM, Feng X, Yang C, Wu S, Zheng Y, Liu X, Cheung KMC, Yeung KWK
ACS applied materials & interfaces 2019 Oct 2;11(39):35513-35524
ACS applied materials & interfaces 2019 Oct 2;11(39):35513-35524
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Li H, Tong X, Xu Y, Wang M, Dai H, Shi T, Sun M, Chen K, Cheng X, Wei Q
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Danggui Buxue Tang promotes the adhesion and migration of bone marrow stromal cells via the focal adhesion pathway in vitro.
Bo H, He J, Wang X, Du R, Bei H, Chen J, Wang J, Wu F, Zhang W, Chen Q
Journal of ethnopharmacology 2019 Mar 1;231:90-97
Journal of ethnopharmacology 2019 Mar 1;231:90-97
BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells.
Chiang HC, Zhang X, Li J, Zhao X, Chen J, Wang HT, Jatoi I, Brenner A, Hu Y, Li R
Nucleic acids research 2019 Jun 4;47(10):5086-5099
Nucleic acids research 2019 Jun 4;47(10):5086-5099
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ
eLife 2019 Jun 11;8
eLife 2019 Jun 11;8
Transcriptional Regulation of ZNF638 in Thermogenic Cells by the cAMP Response Element Binding Protein in Male Mice.
Perie L, Verma N, Xu L, Ma X, Mueller E
Journal of the Endocrine Society 2019 Dec 1;3(12):2326-2340
Journal of the Endocrine Society 2019 Dec 1;3(12):2326-2340
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
Yang C, Li X, Zhang B, Fu S, Li S, Shen J, Guan L, Qiao L, Lin J
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
CRMP4a suppresses cell motility by sequestering RhoA activity in prostate cancer cells.
Li C, Xu H, Xiao L, Zhu H, Zhang G, Wei W, Li K, Cao X, Shen D, Holzbeierlein J, Li B
Cancer biology & therapy 2018;19(12):1193-1203
Cancer biology & therapy 2018;19(12):1193-1203
Recurrent Loss of APOBEC3H Activity during Primate Evolution.
Garcia EI, Emerman M
Journal of virology 2018 Sep 1;92(17)
Journal of virology 2018 Sep 1;92(17)
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer.
Barajas JM, Reyes R, Guerrero MJ, Jacob ST, Motiwala T, Ghoshal K
Scientific reports 2018 Jun 14;8(1):9105
Scientific reports 2018 Jun 14;8(1):9105
The impact of photofunctionalized gold nanoparticles on osseointegration.
Elkhidir Y, Lai R, Feng Z
Heliyon 2018 Jul;4(7):e00662
Heliyon 2018 Jul;4(7):e00662
Focal adhesions are involved in simulated-microgravity-induced basilar and femoral arterial remodelling in rats.
Jiang M, Lyu Q, Bai YG, Liu H, Yang J, Cheng JH, Zheng M, Ma J
Canadian journal of physiology and pharmacology 2018 Aug;96(8):772-782
Canadian journal of physiology and pharmacology 2018 Aug;96(8):772-782
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Ma D, Zheng B, Suzuki T, Zhang R, Jiang C, Bai D, Yin W, Yang Z, Zhang X, Hou L, Zhan H, Wen JK
Circulation research 2017 Mar 3;120(5):799-815
Circulation research 2017 Mar 3;120(5):799-815
ProBDNF inhibits collective migration and chemotaxis of rat Schwann cells.
Ding YQ, Li XY, Xia GN, Ren HY, Zhou XF, Su BY, Qi JG
Tissue & cell 2016 Oct;48(5):503-10
Tissue & cell 2016 Oct;48(5):503-10
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