Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 14892-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14892-1-AP, RRID:AB_2160044
- Product name
- PCK2 antibody
- Antibody type
- Polyclonal
- Description
- PCK2 antibody (Cat. #14892-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Fish oil-derived n-3 polyunsaturated fatty acids downregulate aquaporin 9 protein expression of liver and white adipose tissues in diabetic KK mice and 3T3-L1 adipocytes.
Metabolomic profiling reveals decreased serum cysteine levels during gestational diabetes mellitus progression.
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
Targeting BCAA metabolism to potentiate metformin's therapeutic efficacy in the treatment of diabetes in mice.
Douchi Peptides VY and SFLLR Improve Glucose Homeostasis and Gut Dysbacteriosis in High-Fat Diet-Induced Insulin Resistant Mice.
Exercise postconditioning reduces ischemic injury via suppression of cerebral gluconeogenesis in rats.
MiR-34a-5p promotes hepatic gluconeogenesis by suppressing SIRT1 expression.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Different types of reactions to E7386 among colorectal cancer patient-derived organoids and corresponding CAFs.
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension.
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Effect of 1-Deoxynojirimycin Isolated from Mulberry Leaves on Glucose Metabolism and Gut Microbiota in a Streptozotocin-Induced Diabetic Mouse Model.
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Yu Q, Zuo X, Bai H, Zhang S, Luan J, Zhao Q, Zhao X, Feng X
European journal of pharmacology 2024 May 15;971:176529
European journal of pharmacology 2024 May 15;971:176529
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Yang Y, Qiu W, Xiao J, Sun J, Ren X, Jiang L
Journal of translational medicine 2024 Mar 26;22(1):309
Journal of translational medicine 2024 Mar 26;22(1):309
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Chen LL, Li YQ, Kang ZH, Zhang X, Gu SY, Wang N, Shen XY
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Fish oil-derived n-3 polyunsaturated fatty acids downregulate aquaporin 9 protein expression of liver and white adipose tissues in diabetic KK mice and 3T3-L1 adipocytes.
Iizuka Y, Hirako S, Kim H, Wada N, Ohsaki Y, Yanagisawa N
The Journal of nutritional biochemistry 2024 Feb;124:109514
The Journal of nutritional biochemistry 2024 Feb;124:109514
Metabolomic profiling reveals decreased serum cysteine levels during gestational diabetes mellitus progression.
Lai M, Li J, Yang J, Zhang Q, Gong Y, Ma Y, Fang F, Li N, Zhai Y, Shen T, Peng Y, Liu J, Wang Y
Journal of molecular cell biology 2024 Aug 26;16(3)
Journal of molecular cell biology 2024 Aug 26;16(3)
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
Guo H, Wu H, Hou Y, Hu P, Du J, Cao L, Yang R, Dong X, Li Z
International journal of biological macromolecules 2023 Sep 30;249:126039
International journal of biological macromolecules 2023 Sep 30;249:126039
Targeting BCAA metabolism to potentiate metformin's therapeutic efficacy in the treatment of diabetes in mice.
Zhao X, Zhang X, Pei J, Liu Y, Niu W, Sun H
Diabetologia 2023 Nov;66(11):2139-2153
Diabetologia 2023 Nov;66(11):2139-2153
Douchi Peptides VY and SFLLR Improve Glucose Homeostasis and Gut Dysbacteriosis in High-Fat Diet-Induced Insulin Resistant Mice.
Yu S, Wang W, Wang H, Bu T, Liu L, Zhao R, Li S, Liu D, Wu J
Molecular nutrition & food research 2023 May;67(10):e2200681
Molecular nutrition & food research 2023 May;67(10):e2200681
Exercise postconditioning reduces ischemic injury via suppression of cerebral gluconeogenesis in rats.
Li F, Geng X, Ilagan R, Bai S, Chen Y, Ding Y
Brain and behavior 2023 Jan;13(1):e2805
Brain and behavior 2023 Jan;13(1):e2805
MiR-34a-5p promotes hepatic gluconeogenesis by suppressing SIRT1 expression.
Wang Y, Zhou F, Li M, Zhang Y, Li N, Shao L
Experimental cell research 2022 Nov 1;420(1):113336
Experimental cell research 2022 Nov 1;420(1):113336
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Different types of reactions to E7386 among colorectal cancer patient-derived organoids and corresponding CAFs.
Imai T, Naruse M, Ochiai M, Matsumoto K, Ikeda S, Kani M, Kato Y, Hirayama A, Soga T, Hori Y, Yokoi A, Ochiai A
Oncology letters 2022 Jul;24(1):221
Oncology letters 2022 Jul;24(1):221
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, Han Q, He H, Zhou Q
Cell death & disease 2022 Feb 16;13(2):156
Cell death & disease 2022 Feb 16;13(2):156
Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation.
Li H, Xu Q, Xu C, Hu Y, Yu X, Zhao K, Li M, Li M, Xu J, Kuang H
Frontiers in pharmacology 2021;12:644129
Frontiers in pharmacology 2021;12:644129
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Geng X, Shen J, Li F, Yip J, Guan L, Rajah G, Peng C, DeGracia D, Ding Y
Molecular neurobiology 2021 May;58(5):2309-2321
Molecular neurobiology 2021 May;58(5):2309-2321
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Hu Y, Deng K, Pan M, Liu S, Li W, Huang J, Yao J, Zuo J
American journal of translational research 2020;12(7):3842-3857
American journal of translational research 2020;12(7):3842-3857
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Yang R, Li Y, Cai J, Ji J, Wang Y, Zhang W, Pan W, Chen Y
Food & function 2020 Nov 18;11(11):9675-9685
Food & function 2020 Nov 18;11(11):9675-9685
Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension.
Valuparampil Varghese M, James J, Eccles CA, Niihori M, Rafikova O, Rafikov R
Journal of clinical medicine 2020 Feb 6;9(2)
Journal of clinical medicine 2020 Feb 6;9(2)
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Wang S, Ai H, Liu L, Zhang X, Gao F, Zheng L, Yi J, Sun L, Yu C, Zhao H, Li Y
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
Effect of 1-Deoxynojirimycin Isolated from Mulberry Leaves on Glucose Metabolism and Gut Microbiota in a Streptozotocin-Induced Diabetic Mouse Model.
Hu TG, Wen P, Shen WZ, Liu F, Li Q, Li EN, Liao ST, Wu H, Zou YX
Journal of natural products 2019 Aug 23;82(8):2189-2200
Journal of natural products 2019 Aug 23;82(8):2189-2200
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80
Molecular and cellular endocrinology 2017 May 5;446:70-80
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859
Scientific reports 2016 Apr 25;6:24859
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Cai D, Jia Y, Song H, Sui S, Lu J, Jiang Z, Zhao R
PloS one 2014;9(8):e105504
PloS one 2014;9(8):e105504
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 14892-1-AP(PCK2 antibody) at dilution of 1:200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14892-1-AP(PCK2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PCK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PCK2. This antibody recognizes human,mouse,rat antigen. The PCK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
