Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN117958 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ras-Like Without CAAX 2 (RIT2) (C-Term), (AA 102-113) antibody
- Antibody type
- Polyclonal
- Antigen
- Prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 102-113 of Human ROC2 (C-terminal) coupled to KLH.
- Description
- Delipidation and defibrination.
- Reactivity
- Human, Mouse, Zebrafish
- Host
- Rabbit
- Antigen sequence
Human ROC2 (113 aa 12.6 kDa) 1 madv
edgeet calashsgss gsksggdkmf slkkwn
avam wswdvecdtc aicrvqvmda 61 clrcq
aenkq edcvvvwgec nhsfhnccms lwvkqnn
rcp lcqqdwvvqr igk- Epitope
- C-Term,AA 102-113
- Vial size
- 0.1 mL
- Concentration
- 85 mg/mL (by Refractometry)
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Endometrial stromal sarcoma of the small bowel.
[Short-term therapy with pegylated interferon plus ribavirin for the chronic hepatitis C genotype 2 patients].
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.
SAG/ROC2/Rbx2/Hrt2, a component of SCF E3 ubiquitin ligase: genomic structure, a splicing variant, and two family pseudogenes.
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation.
Ubiquitin and its kin: how close are the family ties?
Protein kinase CKII interacts with and phosphorylates the SAG protein containing ring-H2 finger motif.
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents.
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Kim L, Choi SJ, Park IS, Han JY, Kim JM, Chu YC, Kim KR
Annals of diagnostic pathology 2008 Apr;12(2):128-33
Annals of diagnostic pathology 2008 Apr;12(2):128-33
[Short-term therapy with pegylated interferon plus ribavirin for the chronic hepatitis C genotype 2 patients].
Jung EU, Park JH, Pae KI, Kang SW, Park SJ, Jee SR, Park ET, Lee YJ, Lee SH, Seol SY
The Korean journal of hepatology 2007 Sep;13(3):341-8
The Korean journal of hepatology 2007 Sep;13(3):341-8
Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.
Kim YS, Lee JY, Son MY, Park W, Bae YS
The Journal of biological chemistry 2003 Aug 1;278(31):28462-9
The Journal of biological chemistry 2003 Aug 1;278(31):28462-9
SAG/ROC2/Rbx2/Hrt2, a component of SCF E3 ubiquitin ligase: genomic structure, a splicing variant, and two family pseudogenes.
Swaroop M, Gosink M, Sun Y
DNA and cell biology 2001 Jul;20(7):425-34
DNA and cell biology 2001 Jul;20(7):425-34
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y
Molecular and cellular biology 2000 Nov;20(21):8185-97
Molecular and cellular biology 2000 Nov;20(21):8185-97
Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation.
Swaroop M, Wang Y, Miller P, Duan H, Jatkoe T, Madore SJ, Sun Y
Oncogene 2000 Jun 1;19(24):2855-66
Oncogene 2000 Jun 1;19(24):2855-66
Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G
Trends in cell biology 2000 Aug;10(8):335-42
Trends in cell biology 2000 Aug;10(8):335-42
Protein kinase CKII interacts with and phosphorylates the SAG protein containing ring-H2 finger motif.
Son MY, Park JW, Kim YS, Kang SW, Marshak DR, Park W, Bae YS
Biochemical and biophysical research communications 1999 Oct 5;263(3):743-8
Biochemical and biophysical research communications 1999 Oct 5;263(3):743-8
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ
Genes & development 1999 Jun 15;13(12):1614-26
Genes & development 1999 Jun 15;13(12):1614-26
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ
Molecular cell 1999 Apr;3(4):527-33
Molecular cell 1999 Apr;3(4):527-33
SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents.
Duan H, Wang Y, Aviram M, Swaroop M, Loo JA, Bian J, Tian Y, Mueller T, Bisgaier CL, Sun Y
Molecular and cellular biology 1999 Apr;19(4):3145-55
Molecular and cellular biology 1999 Apr;19(4):3145-55
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW
Science (New York, N.Y.) 1999 Apr 23;284(5414):662-5
Science (New York, N.Y.) 1999 Apr 23;284(5414):662-5
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG Jr, Elledge SJ, Conaway RC, Harper JW, Conaway JW
Science (New York, N.Y.) 1999 Apr 23;284(5414):657-61
Science (New York, N.Y.) 1999 Apr 23;284(5414):657-61
No comments: Submit comment
No validations: Submit validation data