Tissue expression
Cell line expression
Protein structure

KNG1

Kininogen 1
BDK, BK, KNG 
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reduces or depletes angiotensin converting enzyme 2 (ACE2), which results in an increase in levels of des-Arg(9)-bradykinin, a bioactive metabolite of bradykinin that is associated with lung injury and inflammation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2020]
More gene data

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989 antibodies from 44 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
220 antibodies
Atlas Antibodies
2 antibodies
Proteintech Group
4 antibodies
Invitrogen Antibodies
34 antibodies
Biorbyt
202 antibodies
Novus Biologicals
60 antibodies
NovoPro Bioscience Inc.
8 antibodies
FineTest Biotech
3 antibodies
OriGene
12 antibodies
NSJ Bioreagents
7 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
GeneTex
8 antibodies
Aviva Systems Biology
6 antibodies
Acris Antibodies GmbH
13 antibodies
Abgent
5 antibodies
Affinity Biosciences
1 antibody
R&D Systems
8 antibodies
Signalway Antibody LLC
1 antibody
St John's Laboratory
7 antibodies
Everest Biotech
2 antibodies
ProSci
4 antibodies
Abnova Corporation
8 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
1 antibody
Antibodies.com
2 antibodies
QED Bioscience
2 antibodies
Boster Biological Technology
2 antibodies
HUABIO Research
1 antibody
RabMAbs
2 antibodies
MyBioSource
15 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
66 antibodies
Creative Biolabs
33 antibodies
Abbexa
14 antibodies
Leading Biology
5 antibodies
GenWay
7 antibodies
Arigo
3 antibodies
Molecular Innovations
14 antibodies
Creative Diagnostics
7 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
EMD Millipore
1 antibody
Exalpha Biologicals, Inc.
1 antibody