FNab05021

antibody from FineTest Biotech
Targeting: MASP1 CRARF, MASP, PRSS5
Provider product page for FNab05021
Western blot
ELISA

Antibody data

Product number
FNab05021 - Provider product page
Provider
FineTest Biotech
Product name
MASP1 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin(MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
mannan-binding lectin serine peptid
ase 1(C4/C2 activating component of
Ra-reactive factor)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
MASP1 protein structure - FNab05021 shown in red.