Antibody data

Product number
Ab128849 - Provider product page
Provider
Aladdin Scientific
Product name
Recombinant SP1 Antibody
Antibody type
Recombinant
Description
Rabbit anti Human SP1 Antibody, Recombinant, could be used for WB, IHC, IF/ICC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100IF/ICC:1/50-1/200Protein Function:Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 554-568
Vial size
100_l,10_l,1ml,50_l
Concentration
1 mg/ml
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
SP1 protein structure - Ab128849 shown in red.