16821-1-AP

antibody from Proteintech Group

Targeting: SRF MCM1

Provider product page for 16821-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 16821-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#16821-1-AP, RRID:AB_2194384
Product name: SRF antibody
Antibody type: Polyclonal
Description: KD/KO validated SRF antibody (Cat. #16821-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SRF protein structure - 16821-1-AP shown in red.

Submitted references EPC1/2 regulate hematopoietic stem and progenitor cell proliferation by modulating H3 acetylation and DLST.

Liu W, Liu X, Li L, Tai Z, Li G, Liu JX
iScience 2024 Mar 15;27(3):109263

Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor.

Gong Y, Liu M, Zhang Q, Li J, Cai H, Ran J, Ma L, Ma Y, Quan S
Journal of translational medicine 2024 Jun 12;22(1):561

A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection.

Jiang H, Zhao Y, Su M, Sun L, Chen M, Zhang Z, Ilyas I, Wang Z, Little PJ, Wang L, Weng J, Ge J, Xu S
Pharmacological research 2024 Jan;199:107029

Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer.

Peng Y, Lei X, Yang Q, Zhang G, He S, Wang M, Ling R, Zheng B, He J, Chen X, Li F, Zhou Q, Zhao L, Ye G, Li G
Experimental & molecular medicine 2024 Feb;56(2):441-452

Myocardin regulates fibronectin expression and secretion from human pleural mesothelial cells.

Sakai T, Choo YY, Mitsuhashi S, Ikebe R, Jeffers A, Idell S, Tucker TA, Ikebe M
American journal of physiology. Lung cellular and molecular physiology 2024 Apr 1;326(4):L419-L430

Total sesquiterpenoids from Eupatorium lindleyanum DC. attenuate bleomycin-induced lung fibrosis by suppressing myofibroblast transition.

Sun X, Zhu M, Xia W, Xu X, Zhang J, Jiang X
Fitoterapia 2023 Sep;169:105567

Translational landscape of direct cardiac reprogramming reveals a role of Ybx1 in repressing cardiac fate acquisition.

Xie Y, Wang Q, Yang Y, Near D, Wang H, Colon M, Nguyen C, Slattery C, Keepers B, Farber G, Wang TW, Lee SH, Shih YI, Liu J, Qian L
Nature cardiovascular research 2023 Nov;2(11):1060-1077

Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB.

Zhou LY, Jin CX, Wang WX, Song L, Shin JB, Du TT, Wu H
eLife 2023 Nov 20;12

Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.

Xu M, Zhu F, Yin Q, Yin H, Fang S, Luo G, Huang J, Huang W, Liu F, Zhong M, Deng X
Cancers 2023 Feb 19;15(4)

Heterogeneity of T cells and macrophages in chlorine-induced acute lung injury in mice using single-cell RNA sequencing.

Zhao CQ, Liu JZ, Liu MM, Ren XT, Kong DQ, Peng J, Cao M, Liu R, Hai CX, Zhang XD
Inhalation toxicology 2022;34(13-14):399-411

SRSF3 Promotes Angiogenesis in Colorectal Cancer by Splicing SRF.

Chen Y, Yang M, Meng F, Zhang Y, Wang M, Guo X, Yang J, Zhang H, Zhang H, Sun J, Wang W
Frontiers in oncology 2022;12:810610

Generation and Comparative Analysis of an Itga8-CreER (T2) Mouse with Preferential Activity in Vascular Smooth Muscle Cells.

Warthi G, Faulkner JL, Doja J, Ghanam AR, Gao P, Yang AC, Slivano OJ, Barris CT, Kress TC, Zawieja SD, Griffin SH, Xie X, Ashworth A, Christie CK, Bryant WB, Kumar A, Davis MJ, Long X, Gan L, Belin de Chantemele EJ, Lyu Q, Miano JM
Nature cardiovascular research 2022 Nov;1(11):1084-1100

Activin B-activated Cdc42 signaling plays a key role in regulating adipose-derived mesenchymal stem cells-mediated skin wound healing.

Huang S, Wang X, Zhang M, Huang M, Yan Y, Chen Y, Zhang Y, Xu J, Bu L, Fan R, Tang H, Zeng C, Zhang L, Zhang L
Stem cell research & therapy 2022 Jun 11;13(1):248

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages.

Blair L, Pattison MJ, Chakravarty P, Papoutsopoulou S, Bakiri L, Wagner EF, Smale S, Ley SC
Journal of immunology (Baltimore, Md. : 1950) 2022 Feb 15;208(4):941-954

Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors.

Liu L, Kryvokhyzha D, Rippe C, Jacob A, Borreguero-Muñoz A, Stenkula KG, Hansson O, Smith CWJ, Fisher SA, Swärd K
Cellular and molecular life sciences : CMLS 2022 Aug 1;79(8):459

MicroRNA-125b inhibits the proliferation of vascular smooth muscle cells induced by platelet-derived growth factor BB.

Wang X, Chen S, Gao Y, Yu C, Nie Z, Lu R, Sun Y, Guan Z
Experimental and therapeutic medicine 2021 Aug;22(2):791

Galectin-3- Mediated Transdifferentiation of Pulmonary Artery Endothelial Cells Contributes to Hypoxic Pulmonary Vascular Remodeling.

Zhang L, Li YM, Zeng XX, Wang XY, Chen SK, Gui LX, Lin MJ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(2):763-777

Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.

Ahmad A, Zhang W, Wu M, Tan S, Zhu T
Genes & genomics 2018 Mar;40(3):243-251

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

Yao Y, Hu Z, Ye J, Hu C, Song Q, Da X, Yu Y, Li H, Xu C, Chen Q, Wang QK
Journal of the American Heart Association 2017 Jun 25;6(6)

microRNA let-7g suppresses PDGF-induced conversion of vascular smooth muscle cell into the synthetic phenotype.

Wang TM, Chen KC, Hsu PY, Lin HF, Wang YS, Chen CY, Liao YC, Juo SH
Journal of cellular and molecular medicine 2017 Dec;21(12):3592-3601

Pedicled no-touch saphenous vein graft harvest limits vascular smooth muscle cell activation: the PATENT saphenous vein graft study.

Verma S, Lovren F, Pan Y, Yanagawa B, Deb S, Karkhanis R, Quan A, Teoh H, Feder-Elituv R, Moussa F, Souza DS, Fremes SE
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2014 Apr;45(4):717-25

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 16821-1-AP(SRF antibody) at dilution of 1:400
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human brain using 16821-1-AP(SRF antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The SRF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SRF. This antibody recognizes human,mouse,rat antigen. The SRF antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Appendix: 16821-1-AP.pdf

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