BS4177

antibody from Bioworld Technology, Inc
Targeting: SRF MCM1
Provider product page for BS4177
Western blot
Immunohistochemistry

Antibody data

Product number
BS4177 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SRF (phospho S103) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human SRF around the phosphorylation site of Serine 103.
Description
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1) have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SRF protein structure - BS4177 shown in red.