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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [2]
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- Product number
- PA5-68817 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Nrf2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This target displays homology in the following species: Cow: 86%; Dog: 79%; Human: 86%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Yeast: 83%
- Reactivity
- Human, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Studies on male gonadal toxicity of bisphenol A in diabetic rats: An example of exacerbation effect.
Zinc deficient diet increases the toxicity of bisphenol A in rat testis.
Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation.
Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H(2)O(2)-Induced Oxidative Damage.
Sahu C, Singla S, Jena G
Journal of biochemical and molecular toxicology 2022 Apr;36(4):e22996
Journal of biochemical and molecular toxicology 2022 Apr;36(4):e22996
Zinc deficient diet increases the toxicity of bisphenol A in rat testis.
Sahu C, Charaya A, Singla S, Dwivedi DK, Jena G
Journal of biochemical and molecular toxicology 2020 Oct;34(10):e22549
Journal of biochemical and molecular toxicology 2020 Oct;34(10):e22549
Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation.
Das R, Balmik AA, Chinnathambi S
ASN neuro 2020 Jan-Dec;12:1759091420981204
ASN neuro 2020 Jan-Dec;12:1759091420981204
Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H(2)O(2)-Induced Oxidative Damage.
Yang R, Hui Q, Jiang Q, Liu S, Zhang H, Wu J, Lin F, O K, Yang C
Antioxidants (Basel, Switzerland) 2019 Jul 28;8(8)
Antioxidants (Basel, Switzerland) 2019 Jul 28;8(8)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Nrf2 on rat thymus tissue lysate. The sample was probed with a Nrf2 polyclonal antibody (Product # PA5-68817) using a primary antibody dilution of 1.0 µg/mL.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- 13 Figure Effect of BPA and ZDD on testicular protein expressions in different groups. Representative photomicrographs of Western blot analysis and histogram showing catalase, PCNA, Nrf-2, and Keap1 quantification. All the values are shown as mean +- SEM ( n = 3). * P < .05, ** P < .01, and *** P < .001. BPA, bisphenol A; Keap1, Kelch-like ECH-associated protein 1; Nrf-2, nuclear erythroid derived related factor 2; PCNA, proliferating cell nuclear antigen; ZDD, Zinc deficient diet
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- 13 Figure Combined effect of BPA and diabetes (DIA) on the testicular protein expression by immunoblotting; western blot photomicrographs and histograms are showing catalase, Nrf-2, SOD-1, OCT4, and SIRT1 quantification. Values are expressed as mean +- SEM ( n = 3-4). BPA, bisphenol A; Nrf-2, nuclear factor-erythroid 2-related factor 2; ns, not significant; OCT4, octamer-binding transcription factor 4; SIRT1, Sirtulin (silent mating type information regulation 2 homolog) 1; SOD, superoxide dismutase. * p < 0.05
