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- Antigen structure
- References [110]
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- Product number
- 66504-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- NRF2, NFE2L2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated NRF2, NFE2L2 antibody (Cat. #66504-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E9E3
- Vial size
- 20ul, 150ul
Submitted references Arenobufagin inhibits lung metastasis of colorectal cancer by targeting c-MYC/Nrf2 axis.
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
A Novel lncRNA FUAT1/TNS4 Axis Confers Chemoresistance by Suppressing Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer.
ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Dietary Ferulic Acid Increases Endurance Capacity by Promoting Skeletal Muscle Oxidative Phenotype, Mitochondrial Function, and Antioxidant Capacity.
Quercetin attenuates deoxynivalenol-induced intestinal barrier dysfunction by activation of Nrf2 signaling pathway in IPEC-J2 cells and weaned piglets.
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress.
Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway.
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.
Glycosides of Buyang Huanwu decoction inhibits pyroptosis associated with cerebral ischemia-reperfusion through Nrf2-mediated antioxidant signaling pathway both in vivo and in vitro.
Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons.
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.
Meloxicam inhibited oxidative stress and inflammatory response of LPS-stimulated bovine endometrial epithelial cells through Nrf2 and NF-κB pathways.
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
A peptide encoded by lncRNA MIR7-3 host gene (MIR7-3HG) alleviates dexamethasone-induced dysfunction in pancreatic β-cells through the PI3K/AKT signaling pathway.
Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP(+)-Induced SH-SY5Y Cells.
Effects of protocatechuic acid on antioxidant capacity, mitochondrial biogenesis and skeletal muscle fiber transformation.
Hepatic Anti-Oxidative Genes CAT and GPX4 Are Epigenetically Modulated by RORγ/NRF2 in Alphacoronavirus-Exposed Piglets.
Angiotensin-(1-7) ameliorates intestinal barrier dysfunction by activating the Keap1/Nrf2/HO-1 signaling pathway in acute pancreatitis.
Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.
Astragalus polysaccharide ameliorated complex factor-induced chronic fatigue syndrome by modulating the gut microbiota and metabolites in mice.
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids.
Catalpol Ameliorates Oxidative Stress and Neuroinflammation after Traumatic Brain Injury in Rats.
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.
FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway.
Dietary grape seed proanthocyanidin extract supplementation improves antioxidant capacity and lipid metabolism in finishing pigs.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Hydrogen Attenuates Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy by Regulating Iron Metabolism.
5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway.
Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System.
Zinc Oxide Nanoparticle Improves the Intestinal Function of Intrauterine Growth Retardation Finishing Pigs via Regulating Intestinal Morphology, Inflammation, Antioxidant Status and Autophagy.
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Icariside II Attenuates Methamphetamine-Induced Neurotoxicity and Behavioral Impairments via Activating the Keap1-Nrf2 Pathway.
Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway.
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.
Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.
Melatonin protects porcine oocyte from copper exposure potentially by reducing oxidative stress potentially through the Nrf2 pathway.
ROS-responsive PPGF nanofiber membrane as a drug delivery system for long-term drug release in attenuation of osteoarthritis.
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Caspase-8 mutants activate Nrf2 via phosphorylating SQSTM1 to protect against oxidative stress in esophageal squamous cell carcinoma.
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Daphnetin ameliorates Aβ pathogenesis via STAT3/GFAP signaling in an APP/PS1 double-transgenic mouse model of Alzheimer's disease.
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway.
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Procyanidins inhibit zearalenone-induced apoptosis and oxidative stress of porcine testis cells through activation of Nrf2 signaling pathway.
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in vivo.
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62-Keap1-Nrf2 signaling pathway.
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway.
Dietary L-theanine supplementation improves lipid metabolism and antioxidant capacity in weaning piglets.
Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in weaning piglets.
Daidzein supplementation improved fecundity in sows via modulation of ovarian oxidative stress and inflammation.
Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora.
Monosodium urate crystals with controlled shape and aspect ratio for elucidating the pathological progress of acute gout.
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy.
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Sevoflurane preconditioning prevents acute renal injury caused by ischemia-reperfusion in mice via activation of the Nrf2 signaling pathway.
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H(2)O(2)-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
Dihydromyricetin Enhances Intestinal Antioxidant Capacity of Growing-Finishing Pigs by Activating ERK/Nrf2/HO-1 Signaling Pathway.
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Atorvastatin Regulates MALAT1/miR-200c/NRF2 Activity to Protect Against Podocyte Pyroptosis Induced by High Glucose.
Integrating Network Analysis and Metabolomics to Reveal Mechanism of Huaganjian Decoction in Treatment of Cholestatic Hepatic Injury.
Synergistic Protective Effect of Konjac Mannan Oligosaccharides and Bacillus subtilis on Intestinal Epithelial Barrier Dysfunction in Caco-2 Cell Model and Mice Model of Lipopolysaccharide Stimulation.
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways.
Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation by activating the Nrf2 pathway.
Pristimerin reduces dextran sulfate sodium-induced colitis in mice by inhibiting microRNA-155.
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS.
H(2)S probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys434.
Galangin ameliorates severe acute pancreatitis in mice by activating the nuclear factor E2-related factor 2/heme oxygenase 1 pathway.
Dietary dihydromyricetin supplementation enhances antioxidant capacity and improves lipid metabolism in finishing pigs.
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κ
Effect of Quercetin on PC12 Alzheimer's Disease Cell Model Induced by Aβ (25-35) and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway.
Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis.
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection.
Dietary Ferulic Acid Supplementation Improves Antioxidant Capacity and Lipid Metabolism in Weaned Piglets.
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Wang M, Hu S, Yang J, Yuan L, Han L, Liang F, Zhang F, Zhao H, Liu Y, Gao N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155391
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155391
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134
iScience 2024 Mar 15;27(3):109134
A Novel lncRNA FUAT1/TNS4 Axis Confers Chemoresistance by Suppressing Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer.
Liu M, Li H, Li X, Pan B, Zhang J, Pan Y, Shen M, Liu L
Antioxidants & redox signaling 2024 Jul;41(1-3):24-41
Antioxidants & redox signaling 2024 Jul;41(1-3):24-41
ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
Luo M, Bao L, Xue Y, Zhu M, Kumar A, Xing C, Wang JE, Wang Y, Luo W
The Journal of clinical investigation 2024 Jan 23;134(6)
The Journal of clinical investigation 2024 Jan 23;134(6)
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
Dietary Ferulic Acid Increases Endurance Capacity by Promoting Skeletal Muscle Oxidative Phenotype, Mitochondrial Function, and Antioxidant Capacity.
Huang T, Li H, Chen X, Chen D, Yu B, He J, Luo Y, Yan H, Zheng P, Yu J, Huang Z
Molecular nutrition & food research 2024 Feb;68(4):e2200719
Molecular nutrition & food research 2024 Feb;68(4):e2200719
Quercetin attenuates deoxynivalenol-induced intestinal barrier dysfunction by activation of Nrf2 signaling pathway in IPEC-J2 cells and weaned piglets.
Li E, Li C, Horn N, Ajuwon KM
Current research in toxicology 2023;5:100122
Current research in toxicology 2023;5:100122
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Huang Y, Liu Z, Wang X, Li Y, Liu L, Li B
Neurochemical research 2023 Sep;48(9):2808-2825
Neurochemical research 2023 Sep;48(9):2808-2825
CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress.
Wu F, Hu R, Huang X, Lou J, Cai Z, Chen G, Zhao W, Xiong H, Sha SH, Zheng Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115399
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115399
Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway.
Si J, Liu B, Qi K, Chen X, Li D, Yang S, Ji E
Journal of ethnopharmacology 2023 Oct 28;315:116677
Journal of ethnopharmacology 2023 Oct 28;315:116677
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.
Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, Lander GC, Wiseman RL, Bollong MJ
Cell chemical biology 2023 Oct 19;30(10):1295-1302.e4
Cell chemical biology 2023 Oct 19;30(10):1295-1302.e4
Glycosides of Buyang Huanwu decoction inhibits pyroptosis associated with cerebral ischemia-reperfusion through Nrf2-mediated antioxidant signaling pathway both in vivo and in vitro.
She Y, Shao L, Jiao K, Sun R, Lang T, Long H, Tang Y, Zhang W, Ding C, Deng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155001
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155001
Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons.
Yang Y, Yu L, Zhu T, Xu S, He J, Mao N, Liu Z, Wang D
International journal of biological macromolecules 2023 Nov 1;251:126315
International journal of biological macromolecules 2023 Nov 1;251:126315
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation.
Ibrahim L, Stanton C, Nutsch K, Nguyen T, Li-Ma C, Ko Y, Lander GC, Wiseman RL, Bollong MJ
bioRxiv : the preprint server for biology 2023 May 9;
bioRxiv : the preprint server for biology 2023 May 9;
Meloxicam inhibited oxidative stress and inflammatory response of LPS-stimulated bovine endometrial epithelial cells through Nrf2 and NF-κB pathways.
Cui L, Guo J, Wang Z, Zhang J, Li W, Dong J, Liu K, Guo L, Li J, Wang H, Li J
International immunopharmacology 2023 Mar;116:109822
International immunopharmacology 2023 Mar;116:109822
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Jiang H, Fang Y, Wang Y, Li T, Lin H, Lin J, Pan T, Liu Q, Lv J, Chen D, Chen Y
International immunopharmacology 2023 Mar;116:109762
International immunopharmacology 2023 Mar;116:109762
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C, Lu T, Liu M, Yuan X, Li D, Zhang J, Zhou L, Xu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154668
A peptide encoded by lncRNA MIR7-3 host gene (MIR7-3HG) alleviates dexamethasone-induced dysfunction in pancreatic β-cells through the PI3K/AKT signaling pathway.
Mao X, Zhou J, Kong L, Zhu L, Yang D, Zhang Z
Biochemical and biophysical research communications 2023 Mar 5;647:62-71
Biochemical and biophysical research communications 2023 Mar 5;647:62-71
Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP(+)-Induced SH-SY5Y Cells.
Lai X, Zhang Y, Wu J, Shen M, Yin S, Yan J
Neurotoxicity research 2023 Jun;41(3):242-255
Neurotoxicity research 2023 Jun;41(3):242-255
Effects of protocatechuic acid on antioxidant capacity, mitochondrial biogenesis and skeletal muscle fiber transformation.
Yang L, Chen X, Chen D, Yu B, He J, Luo Y, Zheng P, Chen H, Yan H, Huang Z
The Journal of nutritional biochemistry 2023 Jun;116:109327
The Journal of nutritional biochemistry 2023 Jun;116:109327
Hepatic Anti-Oxidative Genes CAT and GPX4 Are Epigenetically Modulated by RORγ/NRF2 in Alphacoronavirus-Exposed Piglets.
Gu H, Liu Y, Zhao Y, Qu H, Li Y, Ahmed AA, Liu HY, Hu P, Cai D
Antioxidants (Basel, Switzerland) 2023 Jun 19;12(6)
Antioxidants (Basel, Switzerland) 2023 Jun 19;12(6)
Angiotensin-(1-7) ameliorates intestinal barrier dysfunction by activating the Keap1/Nrf2/HO-1 signaling pathway in acute pancreatitis.
Gu R, Cui T, Guo Y, Luan Y, Wang X, Liu R, Yin C
Molecular biology reports 2023 Jul;50(7):5991-6003
Molecular biology reports 2023 Jul;50(7):5991-6003
Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.
Huang Q, Zhang Y, Jiang Y, Huang L, Liu Q, Ouyang D
Chinese journal of natural medicines 2023 Jul;21(7):516-526
Chinese journal of natural medicines 2023 Jul;21(7):516-526
Astragalus polysaccharide ameliorated complex factor-induced chronic fatigue syndrome by modulating the gut microbiota and metabolites in mice.
Wei X, Xin J, Chen W, Wang J, Lv Y, Wei Y, Li Z, Ding Q, Shen Y, Xu X, Zhang X, Zhang W, Zu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114862
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114862
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Qin H, Zhuang W, Liu X, Wu J, Li S, Wang Y, Liu X, Chen C, Zhang H
Cell reports 2023 Jul 25;42(7):112745
Cell reports 2023 Jul 25;42(7):112745
Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids.
Liu P, Cheng M, Guo J, Cao D, Luo J, Wan Y, Fang Y, Jin Y, Xie SS, Liu J
Bioorganic & medicinal chemistry 2023 Jan 15;78:117146
Bioorganic & medicinal chemistry 2023 Jan 15;78:117146
Catalpol Ameliorates Oxidative Stress and Neuroinflammation after Traumatic Brain Injury in Rats.
Ni H, Rui Q, Kan X, Gao R, Zhang L, Zhang B
Neurochemical research 2023 Feb;48(2):681-695
Neurochemical research 2023 Feb;48(2):681-695
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.
Wu J, Wang S, Zhao W, Li M, Li S
European journal of pharmacology 2023 Feb 5;940:175391
European journal of pharmacology 2023 Feb 5;940:175391
FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway.
Zhou Y, Chen Y, Shi Y, Wu L, Tan Y, Li T, Chen Y, Xia J, Hu R
The Journal of clinical investigation 2023 Feb 1;133(3)
The Journal of clinical investigation 2023 Feb 1;133(3)
Dietary grape seed proanthocyanidin extract supplementation improves antioxidant capacity and lipid metabolism in finishing pigs.
Feng Y, Chen X, Chen D, He J, Zheng P, Luo Y, Yu B, Huang Z
Animal biotechnology 2023 Dec;34(8):4021-4031
Animal biotechnology 2023 Dec;34(8):4021-4031
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Hydrogen Attenuates Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy by Regulating Iron Metabolism.
Song J, Chen Q, Xu S, Gou Y, Guo Y, Jia C, Zhao C, Zhang Z, Li B, Zhao Y, Ji E
Current issues in molecular biology 2023 Dec 16;45(12):10193-10210
Current issues in molecular biology 2023 Dec 16;45(12):10193-10210
5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway.
Ma Y, Wang Z, Wu X, Ma Z, Shi J, He S, Li S, Li X, Li X, Li Y, Yu J
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1633-1647
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Aug;72(8):1633-1647
Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System.
Jin T, You Y, Fan W, Wang J, Chen Y, Li S, Hong S, Wang Y, Cao R, Yodoi J, Tian H
Antioxidants (Basel, Switzerland) 2023 Aug 31;12(9)
Antioxidants (Basel, Switzerland) 2023 Aug 31;12(9)
Zinc Oxide Nanoparticle Improves the Intestinal Function of Intrauterine Growth Retardation Finishing Pigs via Regulating Intestinal Morphology, Inflammation, Antioxidant Status and Autophagy.
Zhou B, Zhang J, Liu H, Chen S, Wang T, Wang C
Frontiers in veterinary science 2022;9:884945
Frontiers in veterinary science 2022;9:884945
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047
Frontiers in cardiovascular medicine 2022;9:844047
Icariside II Attenuates Methamphetamine-Induced Neurotoxicity and Behavioral Impairments via Activating the Keap1-Nrf2 Pathway.
Huang J, Ding J, Wang Z, Li Y, He Y, Wang X, Fan H, Xie Q, Qiu P
Oxidative medicine and cellular longevity 2022;2022:8400876
Oxidative medicine and cellular longevity 2022;2022:8400876
Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway.
Xia M, Zhang Q, Zhang Y, Li R, Zhao T, Chen L, Liu Q, Zheng S, Li H, Qian Z, Yang L
Frontiers in aging neuroscience 2022;14:905115
Frontiers in aging neuroscience 2022;14:905115
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Wu X, Zhao K, Fang X, Lu F, Cheng P, Song X, Zhang W, Yao C, Zhu J, Chen H
Frontiers in pharmacology 2022;13:845959
Frontiers in pharmacology 2022;13:845959
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Guo K, Liu R, Jing R, Wang L, Li X, Zhang K, Fu M, Ye J, Hu Z, Zhao W, Xu N
Frontiers in pharmacology 2022;13:1036013
Frontiers in pharmacology 2022;13:1036013
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma.
Kang X, Huo Y, Jia S, He F, Li H, Zhou Q, Chang N, Liu D, Li R, Hu Y, Zhang P, Xu A
Frontiers in oncology 2022;12:939605
Frontiers in oncology 2022;12:939605
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ
Cell death & disease 2022 Sep 26;13(9):824
Cell death & disease 2022 Sep 26;13(9):824
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy.
Bian Y, Shi C, Song S, Mu L, Wu M, Qiu D, Dong J, Zhang W, Yuan C, Wang D, Zhou Z, Dong X, Shi Y
Cell and tissue research 2022 Oct;390(1):93-112
Cell and tissue research 2022 Oct;390(1):93-112
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.
Yang PW, Xu PL, Cheng CS, Jiao JY, Wu Y, Dong S, Xie J, Zhu XY
Journal of ethnopharmacology 2022 Oct 28;297:115516
Journal of ethnopharmacology 2022 Oct 28;297:115516
Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.
Qiu L, Liu X, Xia H, Xu C
International journal of molecular sciences 2022 Oct 20;23(20)
International journal of molecular sciences 2022 Oct 20;23(20)
Melatonin protects porcine oocyte from copper exposure potentially by reducing oxidative stress potentially through the Nrf2 pathway.
Zhan C, Cao X, Zhang T, Guo J, Xu G, Wang H, Yang W, Yang L, Che D, Lu W, Ma X
Theriogenology 2022 Nov;193:1-10
Theriogenology 2022 Nov;193:1-10
ROS-responsive PPGF nanofiber membrane as a drug delivery system for long-term drug release in attenuation of osteoarthritis.
Wu J, Qin Z, Jiang X, Fang D, Lu Z, Zheng L, Zhao J
NPJ Regenerative medicine 2022 Nov 3;7(1):66
NPJ Regenerative medicine 2022 Nov 3;7(1):66
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
Guo J, Cheng M, Liu P, Cao D, Luo J, Wan Y, Fang Y, Jin Y, Xie SS, Liu J
European journal of medicinal chemistry 2022 Nov 15;242:114630
European journal of medicinal chemistry 2022 Nov 15;242:114630
Caspase-8 mutants activate Nrf2 via phosphorylating SQSTM1 to protect against oxidative stress in esophageal squamous cell carcinoma.
Li L, Feng R, Li Y, Yu X, Liu Y, Zhao Y, Liu Z
Free radical biology & medicine 2022 Nov 1;192:51-62
Free radical biology & medicine 2022 Nov 1;192:51-62
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Hu S, Luo L, Bian X, Liu RH, Zhao S, Chen Y, Sun K, Jiang J, Liu Z, Zeng L
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Yu X, Jiang N, Li J, Li X, He S
Tissue & cell 2022 Jun;76:101813
Tissue & cell 2022 Jun;76:101813
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Ouyang S, Li H, Lou L, Huang Q, Zhang Z, Mo J, Li M, Lu J, Zhu K, Chu Y, Ding W, Zhu J, Lin Z, Zhong L, Wang J, Yue P, Turkson J, Liu P, Wang Y, Zhang X
Redox biology 2022 Jun;52:102317
Redox biology 2022 Jun;52:102317
Daphnetin ameliorates Aβ pathogenesis via STAT3/GFAP signaling in an APP/PS1 double-transgenic mouse model of Alzheimer's disease.
Gao P, Wang Z, Lei M, Che J, Zhang S, Zhang T, Hu Y, Shi L, Cui L, Liu J, Noda M, Peng Y, Long J
Pharmacological research 2022 Jun;180:106227
Pharmacological research 2022 Jun;180:106227
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Peng J, Cai Z, Wang Q, Zhou J, Xu J, Pan D, Chen T, Zhang G, Tao L, Chen Y, Shen X
Molecules (Basel, Switzerland) 2022 Jun 4;27(11)
Molecules (Basel, Switzerland) 2022 Jun 4;27(11)
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Huang T, Che Q, Chen X, Chen D, Yu B, He J, Chen H, Yan H, Zheng P, Luo Y, Huang Z
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway.
Huang JC, Yue ZP, Yu HF, Yang ZQ, Wang YS, Guo B
Molecular therapy. Nucleic acids 2022 Jun 14;28:435-449
Molecular therapy. Nucleic acids 2022 Jun 14;28:435-449
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Lei S, Feng Y, Huang P, Chen B, Bao K, Wu Q, Zhang H, Huang X
Toxicology 2022 Jul;477:153275
Toxicology 2022 Jul;477:153275
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Wu Y, Wu Y, Yang Y, Yu J, Wu J, Liao Z, Guo A, Sun Y, Zhao Y, Chen J, Xiao Q
Aging cell 2022 Jul;21(7):e13659
Aging cell 2022 Jul;21(7):e13659
Procyanidins inhibit zearalenone-induced apoptosis and oxidative stress of porcine testis cells through activation of Nrf2 signaling pathway.
Yan R, Wang H, Zhu J, Wang T, Nepovimova E, Long M, Li P, Kuca K, Wu W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jul;165:113061
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jul;165:113061
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
Huo K, Ma KG, Guo QY, Duan P, Xu J
International immunopharmacology 2022 Jul;108:108718
International immunopharmacology 2022 Jul;108:108718
Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in vivo.
Chen X, Zhang M, Xue Y, Liang D, An W, Jia G, Zhao H, Liu G, Huang Z
The Journal of nutritional biochemistry 2022 Jan;99:108859
The Journal of nutritional biochemistry 2022 Jan;99:108859
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Guo Z, Chen X, Huang Z, Chen D, Yu J, Yan H, Chen H, He J, Zheng P, Luo Y, Yu B
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Urolithin A alleviates acute kidney injury induced by renal ischemia reperfusion through the p62-Keap1-Nrf2 signaling pathway.
Zhang Y, Liu M, Zhang Y, Tian M, Chen P, Lan Y, Zhou B
Phytotherapy research : PTR 2022 Feb;36(2):984-995
Phytotherapy research : PTR 2022 Feb;36(2):984-995
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway.
Fu Y, Gao J, Li Y, Yang X, Zhang Y
International immunopharmacology 2022 Feb;103:108414
International immunopharmacology 2022 Feb;103:108414
Dietary L-theanine supplementation improves lipid metabolism and antioxidant capacity in weaning piglets.
Chen X, Chen L, Qin Y, Mao Z, Huang Z, Jia G, Zhao H, Liu G
Animal biotechnology 2022 Dec;33(7):1407-1415
Animal biotechnology 2022 Dec;33(7):1407-1415
Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in weaning piglets.
Chen X, Chen L, Qin Y, Mao Z, Jia G, Zhao H, Liu G, Huang Z
Animal biotechnology 2022 Dec;33(7):1389-1397
Animal biotechnology 2022 Dec;33(7):1389-1397
Daidzein supplementation improved fecundity in sows via modulation of ovarian oxidative stress and inflammation.
Xie K, Li Y, He G, Zhao X, Chen D, Yu B, Luo Y, Mao X, Huang Z, Yu J, Luo J, Zheng P, Yan H, Li H, He J
The Journal of nutritional biochemistry 2022 Dec;110:109145
The Journal of nutritional biochemistry 2022 Dec;110:109145
Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora.
Ren X, Miao B, Cao H, Tian X, Shen L, Yang Z, Yuan F, Ding Y
Molecules (Basel, Switzerland) 2022 Dec 28;28(1)
Molecules (Basel, Switzerland) 2022 Dec 28;28(1)
Monosodium urate crystals with controlled shape and aspect ratio for elucidating the pathological progress of acute gout.
Chen C, Wang J, Liang Z, Li M, Fu D, Zhang L, Yang X, Guo Y, Ge D, Liu Y, Sun B
Biomaterials advances 2022 Aug;139:213005
Biomaterials advances 2022 Aug;139:213005
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Huang P, Luo FJ, Ma YC, Wang SX, Huang J, Qin DD, Xue FF, Liu BY, Wu Q, Wang XL, Liu GQ
Food & function 2022 Aug 30;13(17):9032-9048
Food & function 2022 Aug 30;13(17):9032-9048
Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy.
Wang Y, Zhang Y, Chen K, Liu J, Wu D, Cheng Y, Wang H, Li Y
Stem cell research & therapy 2022 Aug 13;13(1):418
Stem cell research & therapy 2022 Aug 13;13(1):418
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Chen X, Wang Y, Chen D, Yu B, Huang Z
Animal biotechnology 2022 Apr;33(2):356-361
Animal biotechnology 2022 Apr;33(2):356-361
Sevoflurane preconditioning prevents acute renal injury caused by ischemia-reperfusion in mice via activation of the Nrf2 signaling pathway.
Wang WX, Zhao ZR, Bai Y, Li YX, Gao XN, Zhang S, Sun YB
Experimental and therapeutic medicine 2022 Apr;23(4):303
Experimental and therapeutic medicine 2022 Apr;23(4):303
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H(2)O(2)-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
Su J, Zhang X, Kan Q, Chu X
Molecules (Basel, Switzerland) 2022 Apr 30;27(9)
Molecules (Basel, Switzerland) 2022 Apr 30;27(9)
Dihydromyricetin Enhances Intestinal Antioxidant Capacity of Growing-Finishing Pigs by Activating ERK/Nrf2/HO-1 Signaling Pathway.
Wei C, Chen X, Chen D, Yu B, Zheng P, He J, Chen H, Yan H, Luo Y, Huang Z
Antioxidants (Basel, Switzerland) 2022 Apr 2;11(4)
Antioxidants (Basel, Switzerland) 2022 Apr 2;11(4)
Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.
Zhou Z, Li H, Bai S, Xu Z, Jiao Y
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Biochemical and biophysical research communications 2022 Apr 16;600:87-93
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Xi X, Li Z, Liu H, Chen S, Liu D
Frontiers in cell and developmental biology 2021;9:816000
Frontiers in cell and developmental biology 2021;9:816000
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844
Oxidative medicine and cellular longevity 2021;2021:8847844
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512
Oxidative medicine and cellular longevity 2021;2021:7292512
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Ni B, Pei W, Qu Y, Zhang R, Chu X, Wang Y, Huang X, You H
Oxidative medicine and cellular longevity 2021;2021:4139048
Oxidative medicine and cellular longevity 2021;2021:4139048
Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.
Liu J, Wu Q, Yang T, Yang F, Guo T, Zhou Y, Han S, Luo Y, Guo T, Luo F, Lin Q
Oxidative medicine and cellular longevity 2021;2021:2637577
Oxidative medicine and cellular longevity 2021;2021:2637577
Atorvastatin Regulates MALAT1/miR-200c/NRF2 Activity to Protect Against Podocyte Pyroptosis Induced by High Glucose.
Zuo Y, Chen L, He X, Ye Z, Li L, Liu Z, Zhou S
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:1631-1645
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:1631-1645
Integrating Network Analysis and Metabolomics to Reveal Mechanism of Huaganjian Decoction in Treatment of Cholestatic Hepatic Injury.
Dong Q, Chen J, Jiang YP, Zhu ZP, Zheng YF, Zhang JM, Zhang Z, Chen WQ, Sun SY, Pang L, Yan X, Liao W, Fu CM
Frontiers in pharmacology 2021;12:773957
Frontiers in pharmacology 2021;12:773957
Synergistic Protective Effect of Konjac Mannan Oligosaccharides and Bacillus subtilis on Intestinal Epithelial Barrier Dysfunction in Caco-2 Cell Model and Mice Model of Lipopolysaccharide Stimulation.
Chen L, Zhang S, Wu S, Ren Z, Liu G, Wu J
Frontiers in immunology 2021;12:696148
Frontiers in immunology 2021;12:696148
Bakuchiol ameliorates cerebral ischemia-reperfusion injury by modulating NLRP3 inflammasome and Nrf2 signaling.
Xu Y, Gao X, Wang L, Yang M, Xie R
Respiratory physiology & neurobiology 2021 Oct;292:103707
Respiratory physiology & neurobiology 2021 Oct;292:103707
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia.
Dąbrowska K, Skowrońska K, Popek M, Albrecht J, Zielińska M
International journal of molecular sciences 2021 Oct 18;22(20)
International journal of molecular sciences 2021 Oct 18;22(20)
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways.
Zhao L, Zhou N, Zhang H, Pan F, Ai X, Wang Y, Hao S, Wang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112582
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112582
Physalin B inhibits PDGF-BB-induced VSMC proliferation, migration and phenotypic transformation by activating the Nrf2 pathway.
Qiu L, Hu L, Liu X, Li W, Zhang X, Xia H, Zhang C
Food & function 2021 Nov 1;12(21):10950-10966
Food & function 2021 Nov 1;12(21):10950-10966
Pristimerin reduces dextran sulfate sodium-induced colitis in mice by inhibiting microRNA-155.
Tian M, Peng S, Wang S, Li X, Li H, Shen L
International immunopharmacology 2021 May;94:107491
International immunopharmacology 2021 May;94:107491
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Yue XF, Shen CX, Wang JW, Dai LY, Fang Q, Long L, Zhi Y, Li XR, Wang YW, Shen GF, Liu ZJ, Shi CM, Li WB
Asian journal of andrology 2021 May-Jun;23(3):249-258
Asian journal of andrology 2021 May-Jun;23(3):249-258
Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats.
Zhang N, Zhao W, Hu ZJ, Ge SM, Huo Y, Liu LX, Gao BL
Scientific reports 2021 Jul 15;11(1):14511
Scientific reports 2021 Jul 15;11(1):14511
DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS.
Zhou J, Qi C, Fang X, Wang Z, Zhang S, Li D, Song J
Life sciences 2021 Jul 1;276:119089
Life sciences 2021 Jul 1;276:119089
H(2)S probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys434.
Li N, Wang J, Zang X, Wang Z, Zhang T, Zhao B, Miao J, Lin Z
Apoptosis : an international journal on programmed cell death 2021 Feb;26(1-2):111-131
Apoptosis : an international journal on programmed cell death 2021 Feb;26(1-2):111-131
Galangin ameliorates severe acute pancreatitis in mice by activating the nuclear factor E2-related factor 2/heme oxygenase 1 pathway.
Song YD, Liu YY, Li DJ, Yang SJ, Wang QF, Liu YN, Li MK, Mei CP, Cui HN, Chen SY, Zhu CJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112293
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112293
Dietary dihydromyricetin supplementation enhances antioxidant capacity and improves lipid metabolism in finishing pigs.
Guo Z, Chen X, Huang Z, Chen D, Yu B, Chen H, Yu J, Yan H, Zheng P, Luo Y
Food & function 2021 Aug 2;12(15):6925-6935
Food & function 2021 Aug 2;12(15):6925-6935
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396
BMC cancer 2021 Apr 12;21(1):396
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Effect of Quercetin on PC12 Alzheimer's Disease Cell Model Induced by Aβ (25-35) and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway.
Yu X, Li Y, Mu X
BioMed research international 2020;2020:8210578
BioMed research international 2020;2020:8210578
Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis.
Wan S, Pan Q, Yang G, Kuang J, Luo S
Oncology letters 2020 Oct;20(4):13
Oncology letters 2020 Oct;20(4):13
Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway.
Niu Q, Sun W, Chen Q, Long Y, Cao W, Wen S, Li A, Dong F, Shi H
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 20;26:e923049
Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection.
Wei Y, Lu M, Mei M, Wang H, Han Z, Chen M, Yao H, Song N, Ding X, Ding J, Xiao M, Hu G
Nature communications 2020 Feb 18;11(1):941
Nature communications 2020 Feb 18;11(1):941
Dietary Ferulic Acid Supplementation Improves Antioxidant Capacity and Lipid Metabolism in Weaned Piglets.
Wang Y, Chen X, Huang Z, Chen D, Yu B, Yu J, Chen H, He J, Luo Y, Zheng P
Nutrients 2020 Dec 12;12(12)
Nutrients 2020 Dec 12;12(12)
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.
Li S, Zhou J, Xu S, Li J, Liu J, Lu Y, Shi J, Zhou S, Wu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073
Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways.
Shen B, Zhao C, Wang Y, Peng Y, Cheng J, Li Z, Wu L, Jin M, Feng H
Journal of cellular and molecular medicine 2019 Jun;23(6):4063-4075
Journal of cellular and molecular medicine 2019 Jun;23(6):4063-4075
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
Activation of the Nuclear Erythroid 2-Related Factor 2 Antioxidant Responsive Element (Nrf2-ARE) Signaling Pathway Alleviates Acute Graft-Versus-Host Disease by Reducing Oxidative Stress and Inhibiting Infiltration of Inflammatory Cells in an Allogeneic Stem Cell Transplantation Mouse Model.
Yi T, Li X, Wang E, Zhang Y, Fu Y, Li J, Jiang T
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 27;24:5973-5979
Medical science monitor : international medical journal of experimental and clinical research 2018 Aug 27;24:5973-5979
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Linetsky M, Bondelid KS, Losovskiy S, Gabyak V, Rullo MJ, Stiadle TI, Munjapara V, Saxena P, Ma D, Cheng YS, Howes AM, Udeigwe E, Salomon RG
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Chemical research in toxicology 2018 Aug 20;31(8):666-679
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