Antibody data
- Antibody Data
- Antigen structure
- References [33]
- Comments [0]
- Validations [0]
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- Product number
- 33123-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- NRF2/NFE2L2 (mouse) antibody
- Antibody type
- Polyclonal
- Description
- NRF2/NFE2L2 (mouse) antibody (Catalog no. 33123-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat and has been validated for the following applications: WB, IF/ICC, ELISA
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
Submitted references Spatholobus suberectus Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling.
Phaseolorin J Alleviates Cellular Inflammation and Oxidative Stress by Inhibiting NLRP3 Inflammasome Expression via the Nrf2/HO-1 Pathway.
Atractylenolide III improves ovarian dysfunction and endometrial receptivity in a PCOS rat model by regulating Cybb-mediated oxidative stress.
Lutein attenuates sodium fluoride (NaF) and gamma-irradiation induced hepatotoxicity via AMPK-PGC1α mitochondrial biogenesis induction.
Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
The Tetradium ruticarpum-Zingiber officinale Roscoe herb pair inhibits atherogenic events: A study of the synergistic effects and active ingredient combination of a two-herb formula.
Catechin promotes osteogenic differentiation via AMPK-mediated autophagy activation in bone marrow mesenchymal stem cells.
Effect of saponins from gynostemma pentaphyllum on iron metabolism in apolipoprotein E deficient mice.
Chlorogenic acid exerts anti-inflammation and neuroprotective effect in pentylenetetrazole-induced epilepsy mouse model by regulating microglia polarization via Nrf2/HO-1 pathway.
Antioxidant properties of low-molecular-weight Ulva prolifera polysaccharides against H₂O₂-induced oxidative damage in BRL 3A cells and zebrafish.
Kaempferol Mitigates Liver Injury Induced by Copper Toxicity Through the Activation of the Sirt1/Nrf2/FOXO3 Signaling Pathway.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Elucidating the Therapeutic Mechanism of Danggui Liuhuang Decoction in Hyperthyroid Kidney Disease: An Integration of Network Pharmacology and Metabolomics.
Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
Forsythiaside A Suppresses Ferroptosis and Mitigates Type 2 Diabetes Osteoporosis Through the NRF2/GPX4 Axis.
Galangin Alleviates Intervertebral Disc Degeneration via the Nrf2/NF-κB Pathway.
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Fufang Huangqi Jianpi Oral Liquid alleviates spleen deficiency diarrhea via modulation of the NF-κB/Nrf2 signaling pathway and apoptosis.
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
RTA 408 attenuates TBHP-Induced apoptosis in nucleus pulposus cells via Nrf2/ARE and NF-κB signaling pathways: in vitro and in vivo evidence for mitigating rats' intervertebral disc degeneration.
Ferulic acid identification in brown rice using untargeted metabolomics and network analysis and its effects in mitigating AFB1-induced hepatic damage.
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway.
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Therapeutic Effects of Phyllanthus urinaria L on Cisplatin-Induced Acute Kidney Injury: Anti-Inflammatory, Anti-Apoptotic, and Anti-Oxidative Action.
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway.
Single-cell RNA-sequencing-guided reactive oxygen species-scavenging hydrogel design for regeneration of osteoporotic bone.
MOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via an Nrf2-Dependent Mechanism.
SIRT2 Inhibition promotes microglia LC3-associated phagocytosis via NRF2/CD36 after the experimental subarachnoid hemorrhage.
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene.
Diminazene Alleviates Neuroinflammation in Ischemic Stroke by Inhibiting Astrocytic Endoplasmic Reticulum Stress and Oxidative Stress.
Chen G, Li H, Chen R, Yao Y, Lian G, Bai L, Chen H, Zhang C, Chen G
International journal of nanomedicine 2026;21:585928
International journal of nanomedicine 2026;21:585928
Phaseolorin J Alleviates Cellular Inflammation and Oxidative Stress by Inhibiting NLRP3 Inflammasome Expression via the Nrf2/HO-1 Pathway.
Chen Y, Feng T, Li X, Xu J, Cen J
Marine drugs 2026 Mar 31;24(4)
Marine drugs 2026 Mar 31;24(4)
Atractylenolide III improves ovarian dysfunction and endometrial receptivity in a PCOS rat model by regulating Cybb-mediated oxidative stress.
Bai C, Liu J
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 30;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 30;
Lutein attenuates sodium fluoride (NaF) and gamma-irradiation induced hepatotoxicity via AMPK-PGC1α mitochondrial biogenesis induction.
Abd-ElRaouf A, Abdou FY, Ali MM, Habieb ME
Molecular biology reports 2026 Mar 25;53(1)
Molecular biology reports 2026 Mar 25;53(1)
Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.
Zhu Q, Xu W, Yang G, Gao Y, Zhao Y, Zhao Z, Kang Y, Li S, Zhao L
International journal of molecular sciences 2026 Mar 16;27(6)
International journal of molecular sciences 2026 Mar 16;27(6)
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
Sun L, Xu B, Liang Y, Tao Y, Wei C, Du W, Chen P, Wang L, Yang X, Chen X
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
The Tetradium ruticarpum-Zingiber officinale Roscoe herb pair inhibits atherogenic events: A study of the synergistic effects and active ingredient combination of a two-herb formula.
Chi C, Yang X, Li C, Li Z, Yang S, Du Y, Huang W, Liu R
Fitoterapia 2026 Jan;188:107030
Fitoterapia 2026 Jan;188:107030
Catechin promotes osteogenic differentiation via AMPK-mediated autophagy activation in bone marrow mesenchymal stem cells.
Liu H, Li A, Yue J, Guo Z, Zhou N, Yuan H, Han L, Han Y, Peng G, Xu Y, Wen F, Zhang Y
Stem cells (Dayton, Ohio) 2026 Jan 29;44(2)
Stem cells (Dayton, Ohio) 2026 Jan 29;44(2)
Effect of saponins from gynostemma pentaphyllum on iron metabolism in apolipoprotein E deficient mice.
Huang T, Xiao X, Ma J, Fang J, Bao Y
European journal of medical research 2026 Jan 12;31(1):260
European journal of medical research 2026 Jan 12;31(1):260
Chlorogenic acid exerts anti-inflammation and neuroprotective effect in pentylenetetrazole-induced epilepsy mouse model by regulating microglia polarization via Nrf2/HO-1 pathway.
Sun Y, Wang J, Zhang A, Hu A, Wu L
Neuroscience letters 2026 Feb 26;873:138493
Neuroscience letters 2026 Feb 26;873:138493
Antioxidant properties of low-molecular-weight Ulva prolifera polysaccharides against H₂O₂-induced oxidative damage in BRL 3A cells and zebrafish.
Tan J, Zheng Y, Ahn G, Wang L, Mao X
Food chemistry 2026 Feb 1;501:147475
Food chemistry 2026 Feb 1;501:147475
Kaempferol Mitigates Liver Injury Induced by Copper Toxicity Through the Activation of the Sirt1/Nrf2/FOXO3 Signaling Pathway.
Xu J, Wan W, Mu H, Gong S, Liu Y, Deng T
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70813
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70813
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Li X, Ye J, Zhong D, Xie J, Ding Z, Zhou M
Biomaterials 2026 Apr;327:123767
Biomaterials 2026 Apr;327:123767
Elucidating the Therapeutic Mechanism of Danggui Liuhuang Decoction in Hyperthyroid Kidney Disease: An Integration of Network Pharmacology and Metabolomics.
Jiang Y, Wang Z, Zhao Y, Yu Q, Weng L, Xiao C
International journal of endocrinology 2025;2025:5513418
International journal of endocrinology 2025;2025:5513418
Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
Ye C, Xu J, Wang Y, Ji M, Tao R, Han F, Zhou P
Regenerative biomaterials 2025;12:rbaf060
Regenerative biomaterials 2025;12:rbaf060
Forsythiaside A Suppresses Ferroptosis and Mitigates Type 2 Diabetes Osteoporosis Through the NRF2/GPX4 Axis.
Huang YX, Bu YT, Zhang YK, Wang YK, Guo YF, Jin C, Feng SX, Kong LF, Chen WK, Yang L
Food science & nutrition 2025 Oct;13(10):e70991
Food science & nutrition 2025 Oct;13(10):e70991
Galangin Alleviates Intervertebral Disc Degeneration via the Nrf2/NF-κB Pathway.
Chen L, Ying S, Guo Z, Tan H, Jin Y, Wang X, Sun J, Zhang X, Zhou C, Chen D, Jiang Y, Peng K
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26060-26072
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26060-26072
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Zhang X, Cui J, Sun J, Wang F, Fan B, Lu C
Nutrients 2025 Oct 12;17(20)
Nutrients 2025 Oct 12;17(20)
Fufang Huangqi Jianpi Oral Liquid alleviates spleen deficiency diarrhea via modulation of the NF-κB/Nrf2 signaling pathway and apoptosis.
Huang L, Qiu Z, Sun K, Yu C, Huang Q, Liu C, Pan X, Li S, Ge S, Shi X, Hu F, Xin R
3 Biotech 2025 Nov;15(11):377
3 Biotech 2025 Nov;15(11):377
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal-Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair.
Sun X, Xu X, Zhao X, Ma J, Wang T, Yue X, Sun X, Li X, Sun X, Zhang W, Zhang K, Zhang D, Zhao X, Jin W, Wang J
ACS nano 2025 Jun 24;19(24):22141-22162
ACS nano 2025 Jun 24;19(24):22141-22162
RTA 408 attenuates TBHP-Induced apoptosis in nucleus pulposus cells via Nrf2/ARE and NF-κB signaling pathways: in vitro and in vivo evidence for mitigating rats' intervertebral disc degeneration.
Chen W, Li D, Chen L, Fei J, Bian M, Zeng Q, Jiang Z, Wu J
Arthritis research & therapy 2025 Jun 19;27(1):128
Arthritis research & therapy 2025 Jun 19;27(1):128
Ferulic acid identification in brown rice using untargeted metabolomics and network analysis and its effects in mitigating AFB1-induced hepatic damage.
Wang Q, Wang G, Wang Y, Fang X, Fu Y, Li G, Huang S, Ma Q, Zhao L
Food & function 2025 Jun 16;16(12):4970-4982
Food & function 2025 Jun 16;16(12):4970-4982
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway.
Zhang J, He S, Wu K, Wei Y, Li C, Zhu Q, Lian S, Wang L, Wan F, Peng F, Zhang J, Chen Z, Zhang X
Scientific reports 2025 Jul 1;15(1):21199
Scientific reports 2025 Jul 1;15(1):21199
Immunomodulatory copper-based polyphenol nanozyme for diabetic infectious wound healing via NIR amplified cuproptosis bacteriostat in synergy with ferroptosis inhibition anti-inflammation.
Gao H, Luo J, Chen X, Huang Y, Mo M, Luo Q, Liu Y, Zou B, Lei Y, Li Z, Huang L, Huang X, Liang P, Lin M, Huang J, Lu H, Huang H, Gao H, Zhang J, Lu J, Gao M
Bioactive materials 2025 Dec;54:759-776
Bioactive materials 2025 Dec;54:759-776
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Kong C, Si C, Liu H, Wang Y, Qiao J, Tang X, Sun H, Zhang J, Chang B
Materials today. Bio 2025 Dec;35:102295
Materials today. Bio 2025 Dec;35:102295
Therapeutic Effects of Phyllanthus urinaria L on Cisplatin-Induced Acute Kidney Injury: Anti-Inflammatory, Anti-Apoptotic, and Anti-Oxidative Action.
Guo Q, Li P, Chen M, Yu Y, Shen L, Long C, Liu X, Wei G, Zhang D
Pediatric discovery 2025 Dec;3(4):e70000
Pediatric discovery 2025 Dec;3(4):e70000
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway.
Zhang H, Hu Q, Zhang Y, Yang L, Tian S, Zhang X, Shen H, Shu H, Xie L, Wu D, Zhou L, Wei X, Cheng C, Jiang J, Wang H, Shen C, Kong D, Xu L
Gut microbes 2025 Dec;17(1):2517821
Gut microbes 2025 Dec;17(1):2517821
Single-cell RNA-sequencing-guided reactive oxygen species-scavenging hydrogel design for regeneration of osteoporotic bone.
Hu W, Fei T, Liu Z, Ding Y, Yu M, Yang F, Zhao F
Journal of Zhejiang University. Science. B 2025 Dec 31;26(12):1172-1191
Journal of Zhejiang University. Science. B 2025 Dec 31;26(12):1172-1191
MOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via an Nrf2-Dependent Mechanism.
Li K, Yang T, Chen F, Lou C, Chen Y, Chen Z, Ye L, Sun X, Liu G, Xie C, Fang J, Hu X, Zhu Y, Liu B, He D, Ma H
Free radical biology & medicine 2025 Dec 16;241:717-731
Free radical biology & medicine 2025 Dec 16;241:717-731
SIRT2 Inhibition promotes microglia LC3-associated phagocytosis via NRF2/CD36 after the experimental subarachnoid hemorrhage.
Sheng B, Chen X, Tao T, Sun J, Li W, Wu L, Peng Z, Li X, Zhou Z, Yu Q, Ling Y, Sherchan P, Flores JJ, Tang J, Huang L, Hang C, Zhang JH
Journal of neuroinflammation 2025 Dec 12;23(1):26
Journal of neuroinflammation 2025 Dec 12;23(1):26
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Zhao L, Du L, Li Y, Guo Y, Pei D, Zhu D, Zhang H
Food science and biotechnology 2025 Aug;34(12):2947-2957
Food science and biotechnology 2025 Aug;34(12):2947-2957
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene.
Gobert AP, Hawkins CV, Snyder LA, Williams KJ, Barry DP, Allaman MM, Asim M, McNamara KM, Carey SM, Delgado AG, Tyree RN, Rose KL, Wang Y, Zhao S, Boutaud O, Zagol-Ikapitte I, Piazuelo MB, Washington MK, Coburn LA, Wilson KT
Cancer letters 2025 Aug 24;633:218002
Cancer letters 2025 Aug 24;633:218002
Diminazene Alleviates Neuroinflammation in Ischemic Stroke by Inhibiting Astrocytic Endoplasmic Reticulum Stress and Oxidative Stress.
Liu C, Peng Q, Wang S, Xu Z, Hong Y, Zhu L, Gu M, Lyu J, Zhang Y, Duan R
Neurochemical research 2025 Aug 21;50(5):272
Neurochemical research 2025 Aug 21;50(5):272
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