orb386055

antibody from Biorbyt
Targeting: NKX2-2 NKX2.2, NKX2B
Provider product page for orb386055
Immunohistochemistry

Antibody data

Product number
orb386055 - Provider product page
Provider
Biorbyt
Product name
NKX2.2 Antibody
Antibody type
Polyclonal
Description
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Vial size
20 ug
Storage
Store the NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
NKX2-2 protein structure - orb386055 shown in red.