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- Antibody Data
- Antigen structure
- References [40]
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- Immunohistochemistry [1]
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- Product number
- 22281-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22281-1-AP, RRID:AB_2736822
- Product name
- MYH6 antibody
- Antibody type
- Polyclonal
- Description
- MYH6 antibody (Cat. #22281-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts.
Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
Regulation of myo-miR-24-3p on the Myogenesis and Fiber Type Transformation of Skeletal Muscle.
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Ascorbic acid induces MLC2v protein expression and promotes ventricular-like cardiomyocyte subtype in human induced pluripotent stem cells derived cardiomyocytes.
Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp.
Circular RNA circIGF2BP3 Promotes the Proliferation and Differentiation of Chicken Primary Myoblasts.
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp.
GLUT4 mediates the protective function of gastrodin against pressure overload-induced cardiac hypertrophy.
The Mouse CircGHR Regulates Proliferation, Differentiation and Apoptosis of Hepatocytes and Myoblasts.
Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction.
Neddylation is required for perinatal cardiac development through stimulation of metabolic maturation.
Unilateral chemical ablation of the adrenal gland lowers blood pressure and alleviates target organ damage in spontaneously hypertensive rats.
Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation.
Appropriate Exogenous Expression Stoichiometry of GATA4 as an Important Factor for Cardiac Reprogramming of Human Dermal Fibroblasts.
MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin.
Dihydromyricetin alters myosin heavy chain expression via AMPK signaling pathway in porcine myotubes.
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
Fat mass and obesity-associated gene (FTO) hypermethylation induced by decabromodiphenyl ethane causing cardiac dysfunction via glucolipid metabolism disorder.
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Cellular Phenotypic Transformation in Heart Failure Caused by Coronary Heart Disease and Dilated Cardiomyopathy: Delineating at Single-Cell Level.
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation.
Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats.
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Asporin is a Potential Promising Biomarker for Common Heart Failure.
Sirtuin 3 deficiency aggravates angiotensin II-induced hypertensive cardiac injury by the impairment of lymphangiogenesis.
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Age-dependent changes in electrophysiology and calcium handling: implications for pediatric cardiac research.
Doxorubicin-induced cardiotoxicity involves IFNγ-mediated metabolic reprogramming in cardiomyocytes.
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Region of Interest analysis using mass spectrometry imaging of mitochondrial and sarcomeric proteins in acute cardiac infarction tissue.
Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.
Skeletal muscle in aged mice reveals extensive transformation of muscle gene expression.
Overexpression of Cardiac-Specific Kinase TNNI3K Promotes Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes.
Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development.
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
Xie R, Yuan S, Hu G, Zhan J, Jin K, Tang Y, Fan J, Zhao Y, Wang F, Chen C, Wang DW, Li H
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1578-1594
Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.
Lou S, Zhu W, Yu T, Zhang Q, Wang M, Jin L, Xiong Y, Xu J, Wang Q, Chen G, Liang G, Hu X, Luo W
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167140
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167140
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
Southwell N, Manzo O, Bacman S, Zhao D, Sayles NM, Dash J, Fujita K, D'Aurelio M, Di Lorenzo A, Manfredi G, Kawamata H
EMBO molecular medicine 2024 Jun;16(6):1352-1378
EMBO molecular medicine 2024 Jun;16(6):1352-1378
Regulation of myo-miR-24-3p on the Myogenesis and Fiber Type Transformation of Skeletal Muscle.
Fan D, Yao Y, Liu Y, Yan C, Li F, Wang S, Yu M, Xie B, Tang Z
Genes 2024 Feb 21;15(3)
Genes 2024 Feb 21;15(3)
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Wu Q, Liu WJ, Ma XY, Chang JS, Zhao XY, Liu YH, Yu XY
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Ascorbic acid induces MLC2v protein expression and promotes ventricular-like cardiomyocyte subtype in human induced pluripotent stem cells derived cardiomyocytes.
Gao Y, Su L, Wei Y, Tan S, Hu Z, Tao Z, Kovalik JP, Soong TW, Zhang J, Pu J, Ye L
Theranostics 2023;13(11):3872-3896
Theranostics 2023;13(11):3872-3896
Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp.
Neininger-Castro AC, Hayes JB Jr, Sanchez ZC, Taneja N, Fenix AM, Moparthi S, Vassilopoulos S, Burnette DT
bioRxiv : the preprint server for biology 2023 Oct 6;
bioRxiv : the preprint server for biology 2023 Oct 6;
Circular RNA circIGF2BP3 Promotes the Proliferation and Differentiation of Chicken Primary Myoblasts.
Wang X, Lin J, Jiao Z, Zhang L, Guo D, An L, Xie T, Lin S
International journal of molecular sciences 2023 Oct 24;24(21)
International journal of molecular sciences 2023 Oct 24;24(21)
miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.
He Y, Yang P, Yuan T, Zhang L, Yang G, Jin J, Yu T
International journal of molecular sciences 2023 Oct 18;24(20)
International journal of molecular sciences 2023 Oct 18;24(20)
Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp.
Neininger-Castro AC, Hayes JB, Sanchez ZC, Taneja N, Fenix AM, Moparthi S, Vassilopoulos S, Burnette DT
eLife 2023 Nov 3;12
eLife 2023 Nov 3;12
GLUT4 mediates the protective function of gastrodin against pressure overload-induced cardiac hypertrophy.
Zhang M, Tan Y, Song Y, Zhu M, Zhang B, Chen C, Liu Y, Shi L, Cui J, Shan W, Jia Z, Feng L, Cao G, Yi W, Sun Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114324
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114324
The Mouse CircGHR Regulates Proliferation, Differentiation and Apoptosis of Hepatocytes and Myoblasts.
Zhang W, Lin S, Jiao Z, An L, Xie T, Wu J, Zhang L
Genes 2023 May 31;14(6)
Genes 2023 May 31;14(6)
Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction.
Li H, Guan K, Liu M, Liu D, Wang W, Zhu A
Food chemistry 2023 Mar 1;403:134473
Food chemistry 2023 Mar 1;403:134473
Neddylation is required for perinatal cardiac development through stimulation of metabolic maturation.
Zou J, Wang W, Lu Y, Ayala J, Dong K, Zhou H, Wang J, Chen W, Weintraub NL, Zhou J, Li J, Su H
Cell reports 2023 Jan 31;42(1):112018
Cell reports 2023 Jan 31;42(1):112018
Unilateral chemical ablation of the adrenal gland lowers blood pressure and alleviates target organ damage in spontaneously hypertensive rats.
Wang X, Luo T, Yang Y, Zhou Y, Hou J, Wang P
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Dec;46(12):2693-2704
Hypertension research : official journal of the Japanese Society of Hypertension 2023 Dec;46(12):2693-2704
Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation.
Wang H, Dou M, Li J, Cao P, Li J, Guo T, Zhao D, Khan A, Li Y, Li B, Qin J, Du R
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):798-809
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):798-809
Appropriate Exogenous Expression Stoichiometry of GATA4 as an Important Factor for Cardiac Reprogramming of Human Dermal Fibroblasts.
Zhang X, Zhang Q, Chen L, Cai B, Zeng M, Ou S, Chen Y, Feng Z, Chen H, Cao S, Kang K
Cellular reprogramming 2022 Oct;24(5):283-293
Cellular reprogramming 2022 Oct;24(5):283-293
MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin.
Zhang X, Chen L, Huang X, Chen H, Cai B, Qin Y, Chen Y, Ou S, Li X, Wu Z, Feng Z, Zeng M, Guo W, Li H, Zhou C, Yu S, Pan M, Liu J, Kang K, Cao S, Pei D
Stem cell reviews and reports 2022 Oct;18(7):2414-2430
Stem cell reviews and reports 2022 Oct;18(7):2414-2430
Dihydromyricetin alters myosin heavy chain expression via AMPK signaling pathway in porcine myotubes.
Guo Z, Chen X, Chen D, Yu B, He J, Zheng P, Luo Y, Chen H, Yan H, Huang Z
Food & function 2022 Oct 17;13(20):10525-10534
Food & function 2022 Oct 17;13(20):10525-10534
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
Pretorius D, Kahn-Krell AM, LaBarge WC, Lou X, Zhang J
iScience 2022 Mar 18;25(3):103824
iScience 2022 Mar 18;25(3):103824
Fat mass and obesity-associated gene (FTO) hypermethylation induced by decabromodiphenyl ethane causing cardiac dysfunction via glucolipid metabolism disorder.
Gao L, Zhang Y, Liu J, Li X, Sang Y, Zhou G, Xue J, Jing L, Shi Z, Wei J, Lu X, Zhou X
Ecotoxicology and environmental safety 2022 Jun 1;237:113534
Ecotoxicology and environmental safety 2022 Jun 1;237:113534
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Yao Q, Wang H, Chen H, Li Z, Jiang Y, Li Z, Wang J, Xing Y, Liu F, Yu D, Yin S
Molecular neurobiology 2022 Jan;59(1):386-404
Molecular neurobiology 2022 Jan;59(1):386-404
Cellular Phenotypic Transformation in Heart Failure Caused by Coronary Heart Disease and Dilated Cardiomyopathy: Delineating at Single-Cell Level.
Zhu L, Wang W, Ren C, Wang Y, Zhang G, Liu J, Wang W
Biomedicines 2022 Feb 8;10(2)
Biomedicines 2022 Feb 8;10(2)
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation.
Wang S, Zhang J, Wu X, Lin X, Liu XM, Zhou J
RNA biology 2021 Sep;18(9):1354-1363
RNA biology 2021 Sep;18(9):1354-1363
Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats.
He X, Yang S, Deng J, Wu Q, Zang WJ
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):878-896
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):878-896
MicroRNA-124-3p affects myogenic differentiation of adipose-derived stem cells by targeting Caveolin-1 during pelvic floor dysfunction in Sprague Dawley rats.
Chen H, Li Z, Lin M, Lv X, Wang J, Wei Q, Zhang Z, Li L
Annals of translational medicine 2021 Jan;9(2):161
Annals of translational medicine 2021 Jan;9(2):161
Asporin is a Potential Promising Biomarker for Common Heart Failure.
Zhang K, Wu M, Qin X, Wen P, Wu Y, Zhuang J
DNA and cell biology 2021 Feb;40(2):303-315
DNA and cell biology 2021 Feb;40(2):303-315
Sirtuin 3 deficiency aggravates angiotensin II-induced hypertensive cardiac injury by the impairment of lymphangiogenesis.
Zhang C, Li N, Suo M, Zhang C, Liu J, Liu L, Qi Y, Zheng X, Xie L, Hu Y, Bu P
Journal of cellular and molecular medicine 2021 Aug;25(16):7760-7771
Journal of cellular and molecular medicine 2021 Aug;25(16):7760-7771
Examination of the Effect of a 50-Hz Electromagnetic Field at 500 μT on Parameters Related With the Cardiovascular System in Rats.
Zhang Y, Li L, Liu X, Ding L, Wu X, Wang J, He M, Hou H, Ruan G, Lai J, Chen C
Frontiers in public health 2020;8:87
Frontiers in public health 2020;8:87
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Jia K, Dai Y, Liu A, Li X, Wu L, Lu L, Bao Y, Jin Q
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, Sun Y, Du H, Wang B, Chen J, Dong S, Lu F, Zhang W
British journal of pharmacology 2020 Feb;177(4):836-856
British journal of pharmacology 2020 Feb;177(4):836-856
Age-dependent changes in electrophysiology and calcium handling: implications for pediatric cardiac research.
Swift LM, Burke M, Guerrelli D, Reilly M, Ramadan M, McCullough D, Prudencio T, Mulvany C, Chaluvadi A, Jaimes R, Posnack NG
American journal of physiology. Heart and circulatory physiology 2020 Feb 1;318(2):H354-H365
American journal of physiology. Heart and circulatory physiology 2020 Feb 1;318(2):H354-H365
Doxorubicin-induced cardiotoxicity involves IFNγ-mediated metabolic reprogramming in cardiomyocytes.
Ni C, Ma P, Wang R, Lou X, Liu X, Qin Y, Xue R, Blasig I, Erben U, Qin Z
The Journal of pathology 2019 Mar;247(3):320-332
The Journal of pathology 2019 Mar;247(3):320-332
[MiR-222-3р Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2].
Yang DL, Gan ML, Tan Y, Ge GH, Li Q, Jiang YZ, Tang GQ, Li MZ, Wang JY, Li XW, Zhang SH, Zhu L
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Molekuliarnaia biologiia 2019 Jan-Feb;53(1):44-52
Region of Interest analysis using mass spectrometry imaging of mitochondrial and sarcomeric proteins in acute cardiac infarction tissue.
Yajima Y, Hiratsuka T, Kakimoto Y, Ogawa S, Shima K, Yamazaki Y, Yoshikawa K, Tamaki K, Tsuruyama T
Scientific reports 2018 May 10;8(1):7493
Scientific reports 2018 May 10;8(1):7493
Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.
Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS
Developmental cell 2018 Jan 8;44(1):87-96.e5
Developmental cell 2018 Jan 8;44(1):87-96.e5
Skeletal muscle in aged mice reveals extensive transformation of muscle gene expression.
Lin IH, Chang JL, Hua K, Huang WC, Hsu MT, Chen YF
BMC genetics 2018 Aug 8;19(1):55
BMC genetics 2018 Aug 8;19(1):55
Overexpression of Cardiac-Specific Kinase TNNI3K Promotes Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes.
Wang Y, Wang SQ, Wang LP, Yao YH, Ma CY, Ding JF, Ye J, Meng XM, Li JJ, Xu RX
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(1):381-398
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(1):381-398
Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development.
Mazzotta S, Neves C, Bonner RJ, Bernardo AS, Docherty K, Hoppler S
Stem cell reports 2016 Oct 11;7(4):764-776
Stem cell reports 2016 Oct 11;7(4):764-776
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
Hinson JT, Chopra A, Nafissi N, Polacheck WJ, Benson CC, Swist S, Gorham J, Yang L, Schafer S, Sheng CC, Haghighi A, Homsy J, Hubner N, Church G, Cook SA, Linke WA, Chen CS, Seidman JG, Seidman CE
Science (New York, N.Y.) 2015 Aug 28;349(6251):982-6
Science (New York, N.Y.) 2015 Aug 28;349(6251):982-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MYH6 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human MYH6. This antibody recognizes human, mouse, rat antigen. The MYH6 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
