ABIN393616
antibody from antibodies-online
Targeting: UBE3A
ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393616 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 51-151) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Rat
- Host
- Mouse
- Epitope
- AA 51-151
- Isotype
- IgG
- Antibody clone number
- 2F6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references A novel UBE3A truncating mutation in large Tunisian Angelman syndrome pedigree.
Kinetics of the transfer of ubiquitin from UbcH7 to E6AP.
Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.
Abaied L, Trabelsi M, Chaabouni M, Kharrat M, Kraoua L, M'rad R, Tebib N, Maazoul F, Chaabouni H
American journal of medical genetics. Part A 2010 Jan;152A(1):141-6
American journal of medical genetics. Part A 2010 Jan;152A(1):141-6
Kinetics of the transfer of ubiquitin from UbcH7 to E6AP.
Purbeck C, Eletr ZM, Kuhlman B
Biochemistry 2010 Feb 23;49(7):1361-3
Biochemistry 2010 Feb 23;49(7):1361-3
Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.
Wang H, Mo P, Ren S, Yan C
The Journal of biological chemistry 2010 Apr 23;285(17):13201-10
The Journal of biological chemistry 2010 Apr 23;285(17):13201-10
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A
Proceedings of the National Academy of Sciences of the United States of America 2010 Apr 13;107(15):6788-93
Proceedings of the National Academy of Sciences of the United States of America 2010 Apr 13;107(15):6788-93
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.
Sanduja S, Kaza V, Dixon DA
Aging 2009 Sep 10;1(9):803-17
Aging 2009 Sep 10;1(9):803-17
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Supportive validation
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- Experimental details
- WB
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- WB
- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
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- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC