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LearnPA3-843
antibody from Invitrogen Antibodies
Targeting: UBE3A
ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A
Western blot
Immunoprecipitation
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- PA3-843 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- E6AP Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Description
- PA3-843 detects Angelman Syndrome-Associated protein (E6-AP) from human tissues. PA3-843 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a single ~100 kDa protein representing E6-AP from HeLa cell lysate. IMPORTANT: E6-AP is a very labile protein. Freeze/thaw cycling of samples results in E6-AP degradation which is observed as a prominent 50 kDa band seen in Western blots. PA3-843 antigen is bacterially expressed, full-length human E6-AP.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- Conc. Not Determined
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis.
Samaco RC, Hogart A, LaSalle JM
Human molecular genetics 2005 Feb 15;14(4):483-92
Human molecular genetics 2005 Feb 15;14(4):483-92
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
Colledge M, Snyder EM, Crozier RA, Soderling JA, Jin Y, Langeberg LK, Lu H, Bear MF, Scott JD
Neuron 2003 Oct 30;40(3):595-607
Neuron 2003 Oct 30;40(3):595-607
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
Colledge M, Snyder EM, Crozier RA, Soderling JA, Jin Y, Langeberg LK, Lu H, Bear MF, Scott JD
Neuron 2003 Oct 30;40(3):595-607
Neuron 2003 Oct 30;40(3):595-607
The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis.
Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW
Breast cancer research and treatment 2000 Aug;62(3):185-95
Breast cancer research and treatment 2000 Aug;62(3):185-95
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