Antibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [2]
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- Product number
- ABIN2845371 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 10-37), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 10-37, N-Term
- Antibody clone number
- RB31989
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression.
LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis.
Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Yao QM, Li PP, Liang SM, Lu K, Zhu XJ, Liu YX, Zhang F, Yuan T, Wang X
International journal of clinical and experimental pathology 2015;8(7):7921-8
International journal of clinical and experimental pathology 2015;8(7):7921-8
LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis.
Gutierrez A Jr, Tschumper RC, Wu X, Shanafelt TD, Eckel-Passow J, Huddleston PM 3rd, Slager SL, Kay NE, Jelinek DF
Blood 2010 Oct 21;116(16):2975-83
Blood 2010 Oct 21;116(16):2975-83
Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.
Chen QY, Zhang T, Pincus SH, Wu S, Ricks D, Liu D, Sun Z, Maclaren N, Lan MS
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5047-54
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5047-54
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP
Human molecular genetics 2010 Jun 15;19(12):2497-506
Human molecular genetics 2010 Jun 15;19(12):2497-506
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB