Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11-1001 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-DRAM Antibody
- Antibody type
- Polyclonal
- Description
- DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant DRAM p
rotein (amino acids 1-230) was used
as the immunogen for this antibody
.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
No comments: Submit comment
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of DRAM. Anti- DRAM antibody (11-1001) was used at 4 µg/ml on (1) Kidney and (2) Lungs lysates.