Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14419-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14419-1-AP, RRID:AB_2198838
- Product name
- TCF12/HEB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TCF12/HEB antibody (Cat. #14419-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4.
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms.
Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon.
TCF12 Activates TGFB2 Expression to Promote the Malignant Progression of Melanoma.
RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12.
Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB.
A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis.
Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo.
TCF12 is mutated in anaplastic oligodendroglioma.
Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation.
Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis.
Zheng H, Fang J, Lu W, Liu Y, Chen S, Huang G, Zou Y, Hu S, Zheng Y, Fang H, Zhang R
Journal of orthopaedic translation 2024 Jan;44:35-46
Journal of orthopaedic translation 2024 Jan;44:35-46
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms.
Shin B, Zhou W, Wang J, Gao F, Rothenberg EV
Nature immunology 2023 Sep;24(9):1458-1472
Nature immunology 2023 Sep;24(9):1458-1472
Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon.
Talley MJ, Nardini D, Ehrman LA, Lu QR, Waclaw RR
Neural development 2023 Sep 8;18(1):5
Neural development 2023 Sep 8;18(1):5
TCF12 Activates TGFB2 Expression to Promote the Malignant Progression of Melanoma.
Tian Y, Zhou J, Chai X, Ping Z, Zhao Y, Xu X, Luo C, Sheng J
Cancers 2023 Sep 11;15(18)
Cancers 2023 Sep 11;15(18)
RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12.
Liu L, Zhou X, Cheng S, Ge Y, Chen B, Shi J, Li H, Li S, Li Y, Yuan J, Wu A, Liu X, Huang S, Xu Z, Dong J
CNS neuroscience & therapeutics 2023 Apr;29(4):988-999
CNS neuroscience & therapeutics 2023 Apr;29(4):988-999
Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB.
Holliday H, Roden D, Junankar S, Wu SZ, Baker LA, Krisp C, Chan CL, McFarland A, Skhinas JN, Cox TR, Pal B, Huntington ND, Ormandy CJ, Carroll JS, Visvader J, Molloy MP, Swarbrick A
iScience 2021 Feb 19;24(2):102072
iScience 2021 Feb 19;24(2):102072
A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis.
Han S, Dennis DJ, Balakrishnan A, Dixit R, Britz O, Zinyk D, Touahri Y, Olender T, Brand M, Guillemot F, Kurrasch D, Schuurmans C
Development (Cambridge, England) 2018 Oct 1;145(19)
Development (Cambridge, England) 2018 Oct 1;145(19)
Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo.
Yi S, Yu M, Yang S, Miron RJ, Zhang Y
Stem cells (Dayton, Ohio) 2017 Feb;35(2):386-397
Stem cells (Dayton, Ohio) 2017 Feb;35(2):386-397
TCF12 is mutated in anaplastic oligodendroglioma.
Labreche K, Simeonova I, Kamoun A, Gleize V, Chubb D, Letouzé E, Riazalhosseini Y, Dobbins SE, Elarouci N, Ducray F, de Reyniès A, Zelenika D, Wardell CP, Frampton M, Saulnier O, Pastinen T, Hallout S, Figarella-Branger D, Dehais C, Idbaih A, Mokhtari K, Delattre JY, Huillard E, Mark Lathrop G, Sanson M, Houlston RS, POLA Network
Nature communications 2015 Jun 12;6:7207
Nature communications 2015 Jun 12;6:7207
Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation.
Bates JG, Salzman J, May D, Garcia PB, Hogan GJ, McIntosh M, Schlissel MS, Brown PO
PloS one 2012;7(5):e37108
PloS one 2012;7(5):e37108
Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis.
Thorsen K, Schepeler T, Øster B, Rasmussen MH, Vang S, Wang K, Hansen KQ, Lamy P, Pedersen JS, Eller A, Mansilla F, Laurila K, Wiuf C, Laurberg S, Dyrskjøt L, Ørntoft TF, Andersen CL
BMC genomics 2011 Oct 14;12:505
BMC genomics 2011 Oct 14;12:505
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 14419-1-AP(TCF12 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TCF12/HEB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TCF12/HEB. This antibody recognizes human,mouse,rat antigen. The TCF12/HEB antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 14419-1-AP(TCF12 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue