Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb1824626 - Provider product page
- Provider
- Biorbyt
- Product name
- MZF1 Antibody / Myeloid zinc finger 1
- Antibody type
- Monoclonal
- Description
- Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- PCRP-MZF1-1E8
- Vial size
- 100 ug
- Storage
- Aliquot the Myeloid zinc finger 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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