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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 22441-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- LARG antibody
- Antibody type
- Polyclonal
- Description
- LARG antibody (Cat. #22441-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β-catenin signalling via interaction with Gli1.
Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance.
RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.
Zhang F, Wang F, He J, Lian N, Wang Z, Shao J, Ding H, Tan S, Chen A, Zhang Z, Wang S, Zheng S
British journal of pharmacology 2021 Jun;178(11):2246-2265
British journal of pharmacology 2021 Jun;178(11):2246-2265
Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance.
Ding Z, Dong Z, Yang Y, Fortin Ensign SP, Sabit H, Nakada M, Ruggieri R, Kloss JM, Symons M, Tran NL, Loftus JC
The American journal of pathology 2020 Oct;190(10):2165-2176
The American journal of pathology 2020 Oct;190(10):2165-2176
RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.
Shi GX, Yang WS, Jin L, Matter ML, Ramos JW
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 9;115(2):E190-E199
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 9;115(2):E190-E199
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 22441-1-AP(LARG antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ARHGEF12 antibody 22441-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
