AMAb90795

antibody from Atlas Antibodies

Targeting: SOX9 CMD1, CMPD1, SRA1

Western blot (Enhanced validation)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AMAb90795

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#AMAb90795, RRID:AB_2665670

Product name

Anti-SOX9

Antibody type

Monoclonal

Description

Monoclonal Antibody against Human SOX9, Clone ID: CL0639, Gene description: SRY (sex determining region Y)-box 9, Alternative Gene Names: CMD1, CMPD1, SRA1, Validated applications: ICC, IHC, WB, Uniprot ID: P48436, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

CL0639

Vial size

100 µl

Concentration

1.0 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Dynamics of HSD17B3 expression in human fetal testis: implications for the role of Sertoli cells in fetal testosterone biosynthesis.

Planinic A, Maric T, Himelreich Peric M, Jezek D, Katusic Bojanac A
Frontiers in cell and developmental biology 2024;12:1429292

---

Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.

Angyal D, Groeneweg TA, Leung A, Desain M, Dulla K, de Jonge HR, Bijvelds MJC
Cellular & molecular biology letters 2024 Jan 23;29(1):18

---

Infection of SARS-CoV-2 causes severe pathological changes in mouse testis

Chen M, Li S, Liu S, Zhang Y, Cui X, Lv L, Liu B, Zheng A, Wang Q, Duo S, Gao F
Journal of Genetics and Genomics 2023;50(2):99-107

---

Human enteroids as a tool to study conventional and ultra-high dose rate radiation

Klett K, Martin-Villa B, Villarreal V, Melemenidis S, Viswanathan V, Manjappa R, Ashraf M, Soto L, Lau B, Dutt S, Rankin E, Loo B, Heilshorn S
Integrative Biology 2023;15

---

KRAS-specific antibody binds to KRAS protein inside colorectal adenocarcinoma cells and inhibits its localization to the plasma membrane

Lam K, Low Y, Lo M, Wong M, Leong Tang C, Tan E, Chok A, Seow-En I, Wong S, Cheah P
Frontiers in Oncology 2023;13

---

KRAS mutation‐independent downregulation of MAPK/PI3K signaling in colorectal cancer

Lam K, Tang C, Tan E, Wong S, Cheah P
Molecular Oncology 2022;16(5):1171-1183

---

PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer

Nimmakayala R, Ogunleye A, Parte S, Krishna Kumar N, Raut P, Varadharaj V, Perumal N, Nallasamy P, Rauth S, Cox J, Lele S, Batra S, Ponnusamy M
Cell Death & Disease 2022;13(10)

---

CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.

Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M
Nature neuroscience 2022 Nov;25(11):1528-1542

---

Stemness and clinical features in relation to the subventricular zone in diffuse lower-grade glioma: an exploratory study.

Corell A, Gómez Vecchio T, Ferreyra Vega S, Dénes A, Neimantaite A, Hagerius A, Barchéus H, Solheim O, Lindskog C, Bontell TO, Carén H, Jakola AS, Smits A
Neuro-oncology advances 2022 Jan-Dec;4(1):vdac074

---

Rejuvenated Vintage Tissue Sections Highlight Individual Antigen Fate During Processing and Long-term Storage

Mascadri F, Bolognesi M, Pilla D, Cattoretti G
Journal of Histochemistry & Cytochemistry 2021;69(10):659-667

---

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Seime T, Akbulut A, Liljeqvist M, Siika A, Jin H, Winski G, van Gorp R, Karlöf E, Lengquist M, Buckler A, Kronqvist M, Waring O, Lindeman J, Biessen E, Maegdefessel L, Razuvaev A, Schurgers L, Hedin U, Matic L
Cells 2021;10(6):1276

---

Generation of orthotopically functional salivary gland from embryonic stem cells

Tanaka J, Ogawa M, Hojo H, Kawashima Y, Mabuchi Y, Hata K, Nakamura S, Yasuhara R, Takamatsu K, Irié T, Fukada T, Sakai T, Inoue T, Nishimura R, Ohara O, Saito I, Ohba S, Tsuji T, Mishima K
Nature Communications 2018;9(1)

---

MALAT1-miR-101-SOX9 feedback loop modulates the chemo-resistance of lung cancer cell to DDP via Wnt signaling pathway

Chen W, Zhao W, Zhang L, Wang L, Wang J, Wan Z, Hong Y, Yu L
Oncotarget 2017;8(55):94317-94329

Western blot

Enhanced validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Genetic validation

Main image

Experimental details

Western blot analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-SOX9 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Sample type

Human

Protocol

Protocol

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human cerebral cortex and liver tissues using AMAb90795 antibody. Corresponding SOX9 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Show more