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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [120]
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- Product number
- 67439-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- SOX9 antibody
- Antibody type
- Monoclonal
- Description
- SOX9 antibody (Cat. #67439-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1H9A6
- Vial size
- 20ul, 150ul
Submitted references Asperuloside-Mediated Activation of Nrf2 Inhibits the NF-κB Pathway and Suppresses Osteoarthritis Progression.
Astragalus membranaceus Polysaccharides Attenuate Osteoarthritis in Human Primary Chondrocytes and in Animal Model: Mechanism Study Using RNA-Seq and Network Pharmacology.
Biomimetic mineralized xenogenic acellular cartilage matrix promotes the repair of osteochondral defects and the recovery of motor function.
Mechano-Iontronic Hydrogels Generating Biomimetic Endogenous Bioelectricity for Promoting Cartilage Regeneration.
Dopamine-functionalized bioinspired pre-chondrogenic hydrogel for cell-free cartilage regeneration.
Dental Pulp Stem Cell-Derived Intracellular Vesicles Promote Cartilage Regeneration and Alleviate Pain in Temporomandibular Joint Osteoarthritis.
Oncogenic role of PLOD3 mediated by SOX9 through IL-6/JAK/STAT3 pathway in cervical cancer.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery and rapid hair regeneration.
HDAC6 exacerbates osteoarthritis by promoting macrophage inflammation-mediated chondrocyte degeneration.
Bone remodeling stimulated by Wnt-mediated mitophagy regulated extracellular vesicles in subchondral bone contributes to osteoarthritis development.
IL-6 signaling is required for the development and regeneration of ear cartilage in microtia.
Rabbits as preclinical animal models of cam morphology: proof of concept.
A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis.
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Atorvastatin improves spermatogenesis in murine and in vitro human chronic orchitis models through restoring blood-testis barriers.
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury.
Membrane-anchored tissue inhibitor of matrix metalloproteinase (TIMP)-1 promotes cell death in head and neck cancer by inducing DNA damage, accumulating collagen II and disrupting cell survival mechanisms.
Astragalus polysaccharide alleviates oxidative stress and senescence in chondrocytes in osteoarthritis via GCN2/ATF4/TXN axis.
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
ZC3H13 Promotes NSUN4-Mediated Chondrocyte Mitochondrial Dysfunction and Pyroptosis in Temporomandibular Joint Osteoarthritis.
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Oxytocin-loaded hydrogel promotes cartilage regeneration and regulates microenvironment.
Harnessing Anti-Inflammatory and Regenerative Potential: GelMA Hydrogel Loaded with IL-10 and Kartogenin for Intervertebral Disc Degeneration Therapy.
Vaccarin ameliorates osteoarthritis by suppressing the c-Jun N-terminal kinase (JNK)-serum amyloid A2 (SAA2) pathway mediating chondrocyte senescence.
MXene-Based Cartilage-Adhesive Microspheres for Photothermal-Controlled Hydrophobic Drug Release and Mesenchymal Stem Cell Delivery in Osteoarthritis.
PTH Promotes Chondrogenesis of Fibrocartilage Stem Cells and Alleviates Temporomandibular Joint Osteoarthritis.
Mechanical Load-Induced Upregulation of Talin2 through Non-Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis.
Rutin protects the pancreas from inflammatory injury and oncogene-driven tumorigenesis by inhibiting acinar to ductal metaplasia.
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Exosome-Functionalized Hydrogels Improve Cartilage Repair by Modulating BMSCs Migration and Differentiation.
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
Efficiently directing differentiation and homing of mesenchymal stem cells to boost cartilage repair in osteoarthritis via a nanoparticle and peptide dual-engineering strategy.
Enhanced Chondrogenic Potential and Osteoarthritis Treatment Using Cyaonoside A-Induced MSC Delivered via a Hyaluronic Acid-Based Hydrogel System.
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9.
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81.
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Revolutionizing the treatment of intervertebral disc degeneration: an approach based on molecular typing.
Integrating superlubricative nanomaterials with precision drug delivery for advanced osteoarthritis therapy.
Gut microbiota-metabolite crosstalk mediates icariin's protection against obesity-induced spermatogenic dysfunction through NF-κB/AMH axis in Sertoli cells.
TLR4-IN-C34 attenuates the progression of osteoarthritis through inhibiting inflammation, angiogenesis and pain.
MFAP5 Activates ITGA5 to Drive Tooth Germ Mineralization Through the MAPK/ERK Pathway: Insights from Single-Cell Transcriptomics.
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
A novel variant in the MAP3K1 genomic locus reveals abnormal cell apoptosis as a potential pathogenic mechanism in 46, XY disorders of sex development.
DNA Origami-Based CD44-Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression.
m6A mRNA demethylase FTO promotes chondrogenic differentiation of human bone marrow mesenchymal stem cells by targeting SMAD3.
Fullerenol Doped Matrigel Promotes Maturation of Intestinal Organoids by Inhibiting Oxidative Stress and Apoptosis.
Synergizing adaptive immunity and regenerative signals to enhance osteochondral defects repair.
Lycium-Barbarum Polysaccharide-Loaded Dual-Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species.
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Promoting chondrogenesis by targeted delivery to the degenerating cartilage in early treatment of osteoarthritis.
Enhancing long-segmental tracheal restoration: A self-repairing hydrogel loaded with chondrocytokines for sutureless anastomosis and cartilage regeneration.
Therapeutic framework nucleic acid complexes targeting oxidative stress and pyroptosis for the treatment of osteoarthritis.
Cyclic negative pressure promotes chondrocyte growth: Association of IGF-2 with EGR-1.
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Differential impact of chronic intermittent hypoxia and stress changes on condylar development.
Tetrahedral Framework Nucleic Acid-Based Delivery of Astaxanthin Suppresses Chondrocyte Pyroptosis and Modulates Oxidative Stress for the Treatment of Osteoarthritis.
RIP1 inhibition reduces chondrocyte apoptosis through downregulating nuclear factor-kappa B signaling in a mouse osteoarthritis model.
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology.
Enhanced therapeutic potential of a self-healing hyaluronic acid hydrogel for early intervention in osteoarthritis.
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
True-bone-ceramics / type I collagen scaffolds for repairing osteochondral defect.
Wedelolactone alleviates inflammation and cartilage degeneration by suppressing the NF-κB signaling pathway in osteoarthritis.
Targeted lipid nanoparticles distributed in hydrogel treat osteoarthritis by modulating cholesterol metabolism and promoting endogenous cartilage regeneration.
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway.
4-Octyl itaconate protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by inhibiting GPX4 methylation in osteoarthritis.
Long noncoding RNA UCA1 promotes the chondrogenic differentiation of human bone marrow mesenchymal stem cells via regulating PARP1 ubiquitination.
Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.
Injectable silk fibroin peptide nanofiber hydrogel composite scaffolds for cartilage regeneration.
Curcumin Ameliorates Age-Induced Tight Junction Impaired in Porcine Sertoli Cells by Inactivating the NLRP3 Inflammasome through the AMPK/SIRT3/SOD2/mtROS Signaling Pathway.
Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors.
Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation.
Comprehensive analysis, immune, and cordycepin regulation for SOX9 expression in pan-cancers and the matched healthy tissues.
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Comprehensive Analysis of the Transcriptome-Wide m(6)A Methylome in Shaziling Pig Testicular Development.
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3.
Spatial and Temporal Expression of Ectodysplasin-A Signaling Pathway Members During Mandibular Condylar Development in Postnatal Mice.
Long non-coding RNA MIR22HG suppresses the chondrogenic differentiation of human adipose-derived stem cells by interacting with CTCF to upregulate CRLF1.
CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma.
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
TNF-α activates RELA expression via TNFRSF1B to upregulate OPA1 expression and inhibit chondrogenic differentiation of human adipose stem cells.
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy.
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
MiR-203a-3p attenuates apoptosis and pyroptosis of chondrocytes by regulating the MYD88/NF-κB pathway to alleviate osteoarthritis progression.
Growth differentiation factor 5 inhibits lipopolysaccharide-mediated pyroptosis of nucleus pulposus mesenchymal stem cells via RhoA signaling pathway.
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice.
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling.
Dual-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration therapy.
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
SOX9 negatively regulates the RLR antiviral signaling by targeting MAVS.
Electroacupuncture Upregulates HIF-1α and SOX9 Expression in Knee Osteoarthritis.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
LncRNA NONHSAT030515 promotes the chondrogenic differentiation of human adipose-derived stem cells via regulating the miR-490-5p/BMPR2 axis.
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Zhu L, Shen H, Huang C, Jiang H, Yan Z, Pan X, Lu Z
Phytotherapy research : PTR 2026 May;40(5):3027-3046
Phytotherapy research : PTR 2026 May;40(5):3027-3046
Astragalus membranaceus Polysaccharides Attenuate Osteoarthritis in Human Primary Chondrocytes and in Animal Model: Mechanism Study Using RNA-Seq and Network Pharmacology.
Xu H, Li Y, Wang J, Xin Y, Xu Q, Qin X, Yang X, Yan Y, Chen Q, Chen Y, Zhang Y, Lu C, Xu K, Wang X
Phytotherapy research : PTR 2026 May;40(5):2249-2269
Phytotherapy research : PTR 2026 May;40(5):2249-2269
Biomimetic mineralized xenogenic acellular cartilage matrix promotes the repair of osteochondral defects and the recovery of motor function.
Wei Y, Liao H, Guo H, Li Z, Zhao J, Yeung KWK, Chen S, Zeng C
Biomaterials 2026 Mar;326:123722
Biomaterials 2026 Mar;326:123722
Mechano-Iontronic Hydrogels Generating Biomimetic Endogenous Bioelectricity for Promoting Cartilage Regeneration.
Li L, Li Z, Yue M, Shao Y, Wang J, Song Y, Wang ZL, Zhou Y, Pu X
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(2):e14604
Advanced materials (Deerfield Beach, Fla.) 2026 Jan;38(2):e14604
Dopamine-functionalized bioinspired pre-chondrogenic hydrogel for cell-free cartilage regeneration.
Zhu Q, Zhu L, Lang J, Zhu J, Chen D, Huang Y, Zhang J, Wu X, Hu J, Ji J, Yang Q, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114407
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114407
Dental Pulp Stem Cell-Derived Intracellular Vesicles Promote Cartilage Regeneration and Alleviate Pain in Temporomandibular Joint Osteoarthritis.
Shu C, Luo Y, Liu Y, Wang J, Qin Q, Li Z, Situ J, Liu X, Wang X, He Y, Ye Q
International dental journal 2026 Feb;76(1):103974
International dental journal 2026 Feb;76(1):103974
Oncogenic role of PLOD3 mediated by SOX9 through IL-6/JAK/STAT3 pathway in cervical cancer.
Li J, Li J, Chen X
Cellular signalling 2026 Feb;138:112250
Cellular signalling 2026 Feb;138:112250
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
Yu T, Sun X, Liu Y, Dou Y, Tian Y, Zhang Y, Wang G, Wang L, Han J, Li X, Cheng X, Li H, Pan H, Yang L, Zhao Y, Yang Q
Bioactive materials 2026 Apr;58:531-549
Bioactive materials 2026 Apr;58:531-549
Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery and rapid hair regeneration.
Wang S, Sun J, Li Y, Zhou Y, Cai Y, Simayijiang Z, Gu Z, Xie Z
Materials today. Bio 2026 Apr;37:102997
Materials today. Bio 2026 Apr;37:102997
HDAC6 exacerbates osteoarthritis by promoting macrophage inflammation-mediated chondrocyte degeneration.
Wang S, Fu L, Qiu W, Ouyang J, Song D, Song Z, Zhu Y, Yan Z, Jin F, Lu YJ, Liu G
International immunopharmacology 2026 Apr 1;174:116399
International immunopharmacology 2026 Apr 1;174:116399
Bone remodeling stimulated by Wnt-mediated mitophagy regulated extracellular vesicles in subchondral bone contributes to osteoarthritis development.
Gu Y, Zhou Q, Sheng S, Yang H, Huang D, Zhang Q, Zhang H, Cao Z, Zhang Y, Li Z, Jiang Y, Chen X, Jing Y, Wang C, Tan H, Xu K, Su J
Theranostics 2025;15(18):10007-10027
Theranostics 2025;15(18):10007-10027
IL-6 signaling is required for the development and regeneration of ear cartilage in microtia.
Luan W, Fan S, Jiang H, Jiang D, Yang J, He L
Frontiers in cell and developmental biology 2025;13:1625058
Frontiers in cell and developmental biology 2025;13:1625058
Rabbits as preclinical animal models of cam morphology: proof of concept.
Li Z, Wan P, Liu X, Jiang G, Li J, Chen D, Zhang W, Tian K
BMC musculoskeletal disorders 2025 Oct 6;26(1):918
BMC musculoskeletal disorders 2025 Oct 6;26(1):918
A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis.
Huang H, Tang M, Hu P, Zhan Y, Sun W, Zheng W, Zhu J, Chen J, Xue S, Huang S, Han W, Zhang C, Ding C, Zhang Y, Li S, Ruan G
Journal of nanobiotechnology 2025 Oct 31;23(1):695
Journal of nanobiotechnology 2025 Oct 31;23(1):695
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Li J, Tang C, Zhang X, Xing R, Guo Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Atorvastatin improves spermatogenesis in murine and in vitro human chronic orchitis models through restoring blood-testis barriers.
Ma L, Chen J, Li Q, Zhu Y, Ren S, Song K, Yao Z, Yang X, Zheng Y, Liu Z, Wang Z, Miao K, Chen S, Zhao XY, Luo F
Cell death discovery 2025 Nov 6;11(1):505
Cell death discovery 2025 Nov 6;11(1):505
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury.
Tu YJ, Liu YQ, Pan YY, Cai HY, Liu C
World journal of stem cells 2025 Nov 26;17(11):112393
World journal of stem cells 2025 Nov 26;17(11):112393
Membrane-anchored tissue inhibitor of matrix metalloproteinase (TIMP)-1 promotes cell death in head and neck cancer by inducing DNA damage, accumulating collagen II and disrupting cell survival mechanisms.
Zhang P, Gao Y, Tao R, Zheng J, Fu Y, He Y, Meng Q, Lee MH
International journal of biological macromolecules 2025 May;310(Pt 4):143558
International journal of biological macromolecules 2025 May;310(Pt 4):143558
Astragalus polysaccharide alleviates oxidative stress and senescence in chondrocytes in osteoarthritis via GCN2/ATF4/TXN axis.
Chen K, Qin C, Ji C, Yu Y, Wu Y, Xu L, Jiang Y, Zou G
International journal of biological macromolecules 2025 May;310(Pt 3):143285
International journal of biological macromolecules 2025 May;310(Pt 3):143285
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
Zeng J, Yuan L, Chen G, Qi Y, Qie X, Jin Y, Chen Y, Li H
Free radical biology & medicine 2025 May;232:97-106
Free radical biology & medicine 2025 May;232:97-106
ZC3H13 Promotes NSUN4-Mediated Chondrocyte Mitochondrial Dysfunction and Pyroptosis in Temporomandibular Joint Osteoarthritis.
Chen Y, Ren H
Cartilage 2025 May 28;:19476035251339410
Cartilage 2025 May 28;:19476035251339410
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Feng X, Ma Y, Zhao Y, Zhao Z, Song Z, Lin L, Wang W
Molecular immunology 2025 Mar;179:94-105
Molecular immunology 2025 Mar;179:94-105
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
Stem cell research & therapy 2025 Mar 31;16(1):161
Stem cell research & therapy 2025 Mar 31;16(1):161
Oxytocin-loaded hydrogel promotes cartilage regeneration and regulates microenvironment.
Wang T, Zhao X, Li J, Yin C, Jiang B, Xie J, Wang B, Wang Y, Cao Z, Yao Q, Zheng S, Sui J, Zhu K
Biofabrication 2025 Mar 26;17(2)
Biofabrication 2025 Mar 26;17(2)
Harnessing Anti-Inflammatory and Regenerative Potential: GelMA Hydrogel Loaded with IL-10 and Kartogenin for Intervertebral Disc Degeneration Therapy.
Yang S, Shi J, Qiao Y, Teng Y, Zhong X, Wu T, Liu C, Ge J, Yang H, Zou J
ACS biomaterials science & engineering 2025 Mar 10;11(3):1486-1497
ACS biomaterials science & engineering 2025 Mar 10;11(3):1486-1497
Vaccarin ameliorates osteoarthritis by suppressing the c-Jun N-terminal kinase (JNK)-serum amyloid A2 (SAA2) pathway mediating chondrocyte senescence.
Gan X, Li J, Jiang Y, Wang X, Zeng Y, Chen X, Huang H, Min J, Li G, Nie M, Kang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156697
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156697
MXene-Based Cartilage-Adhesive Microspheres for Photothermal-Controlled Hydrophobic Drug Release and Mesenchymal Stem Cell Delivery in Osteoarthritis.
Chen F, Wang W, Zhao H, Zhang Z, Pang N, Tang Y, Wang T, Liu C, Huang Z, Mou F, Yu C, Zhang H
ACS nano 2025 Jun 10;19(22):20502-20515
ACS nano 2025 Jun 10;19(22):20502-20515
PTH Promotes Chondrogenesis of Fibrocartilage Stem Cells and Alleviates Temporomandibular Joint Osteoarthritis.
Yue Z, Gong W, Chu H, Li Y
Tissue engineering and regenerative medicine 2025 Jul;22(5):705-718
Tissue engineering and regenerative medicine 2025 Jul;22(5):705-718
Mechanical Load-Induced Upregulation of Talin2 through Non-Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis.
Huang Y, Sun H, Chen H, Wang X, Zhao J, Jiao Y, Zhou H, Cai H, Dai J, Huang X, Chen W, Shen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501046
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501046
Rutin protects the pancreas from inflammatory injury and oncogene-driven tumorigenesis by inhibiting acinar to ductal metaplasia.
Wang X, Gong M, Zhu Z, Zhang B, Han L, Li W, Wu Z, Ma Q, Wang Z, Qian W
European journal of pharmacology 2025 Jul 5;998:177536
European journal of pharmacology 2025 Jul 5;998:177536
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Kang J, Jie L, Fu H, Zhang L, Lu G, Yu L, Tian D, Liao T, Yin S, Xin R, Wang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
Exosome-Functionalized Hydrogels Improve Cartilage Repair by Modulating BMSCs Migration and Differentiation.
Pei L, Wang Y, Ye M, Sun W, Zhang J, Gao P, Tao Z, Liu D, Jing J, Guan J
ACS applied materials & interfaces 2025 Jul 23;17(29):41729-41746
ACS applied materials & interfaces 2025 Jul 23;17(29):41729-41746
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
Casey-Clyde T, Liu SJ, Pelonero A, Serrano JAC, Teng C, Jang YG, Vasudevan HN, Padmanabhan A, Bush JO, Raleigh DR
bioRxiv : the preprint server for biology 2025 Jul 21;
bioRxiv : the preprint server for biology 2025 Jul 21;
Efficiently directing differentiation and homing of mesenchymal stem cells to boost cartilage repair in osteoarthritis via a nanoparticle and peptide dual-engineering strategy.
Wu C, Huang Z, Chen J, Li N, Cai Y, Chen J, Ruan G, Han W, Ding C, Lu Y
Biomaterials 2025 Jan;312:122720
Biomaterials 2025 Jan;312:122720
Enhanced Chondrogenic Potential and Osteoarthritis Treatment Using Cyaonoside A-Induced MSC Delivered via a Hyaluronic Acid-Based Hydrogel System.
An X, Zhou Q, Sheng S, Deng A, Liu H, Wang X, Zhang Q, Jing Y, Xu K, He C, Zhao RC, Su J
Aging and disease 2025 Jan 29;17(1):466-482
Aging and disease 2025 Jan 29;17(1):466-482
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9.
Zhou C, Feng Z, Qian W, Zhu Z, Cao R, Wang Q, Zhang W, Liu R, Wu S, Hao J, Wang Z, Ma Q, Wu Z, Li X
Biology direct 2025 Jan 14;20(1):6
Biology direct 2025 Jan 14;20(1):6
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Chen J, Sheng R, Mo Q, Backman LJ, Lu Z, Long Q, Chen Z, Cao Z, Zhang Y, Liu C, Zheng H, Qi Y, Cao M, Rui Y, Zhang W
Bioactive materials 2025 Feb;44:319-338
Bioactive materials 2025 Feb;44:319-338
Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81.
Wang M, Wu Z, Zheng X, Huang Y, Jin Y, Song J, Lei W, Liu H, Yu R, Yang H, Gao R
Stem cell research & therapy 2025 Feb 7;16(1):55
Stem cell research & therapy 2025 Feb 7;16(1):55
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Xu H, He Y, Chen S, Meng C, Liu Q, Huang XJ, You HB
International immunopharmacology 2025 Feb 6;147:114027
International immunopharmacology 2025 Feb 6;147:114027
Revolutionizing the treatment of intervertebral disc degeneration: an approach based on molecular typing.
Chen S, Zhang W, Liu Y, Huang R, Zhou X, Wei X
Journal of translational medicine 2025 Feb 25;23(1):227
Journal of translational medicine 2025 Feb 25;23(1):227
Integrating superlubricative nanomaterials with precision drug delivery for advanced osteoarthritis therapy.
Gan X, Li J, Li S, Wang X, Wang Q, Chen X, Huang Y, Nie M, Kang H, Dai H
Materials today. Bio 2025 Dec;35:102359
Materials today. Bio 2025 Dec;35:102359
Gut microbiota-metabolite crosstalk mediates icariin's protection against obesity-induced spermatogenic dysfunction through NF-κB/AMH axis in Sertoli cells.
Huang Q, Ji L, Meng Z, Huang K, Lei S, Xue H, Zhou Q, Tian Y, Chen T, Lei X, Huang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157490
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157490
TLR4-IN-C34 attenuates the progression of osteoarthritis through inhibiting inflammation, angiogenesis and pain.
Wei K, Zou Y, Xu H, Liu H, Liu C
Cellular signalling 2025 Dec;136:112084
Cellular signalling 2025 Dec;136:112084
MFAP5 Activates ITGA5 to Drive Tooth Germ Mineralization Through the MAPK/ERK Pathway: Insights from Single-Cell Transcriptomics.
Wang X, Gu L, Zhang P, Zhou Y
International journal of molecular sciences 2025 Dec 30;27(1)
International journal of molecular sciences 2025 Dec 30;27(1)
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
Casey-Clyde T, Liu SJ, Pelonero A, Serrano JAC, Teng C, Jang YG, Vasudevan HN, Padmanabhan A, Bush JO, Raleigh DR
eLife 2025 Dec 2;13
eLife 2025 Dec 2;13
A novel variant in the MAP3K1 genomic locus reveals abnormal cell apoptosis as a potential pathogenic mechanism in 46, XY disorders of sex development.
Lu Y, Wei S, Wang S, Zhang J, Xu Y, Huang C, Pan W, Wang Z
Molecular medicine reports 2025 Aug;32(2)
Molecular medicine reports 2025 Aug;32(2)
DNA Origami-Based CD44-Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression.
Lv Q, Zhao X, Teng S, Jin X, Zhou Y, Sun Y, Pei H, Yan Z, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03939
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e03939
m6A mRNA demethylase FTO promotes chondrogenic differentiation of human bone marrow mesenchymal stem cells by targeting SMAD3.
Shu T, Zhang D, Li J, Liu H, Cui L, Gu J, Wu L, Liu W, Wan J, Zheng X
Stem cells (Dayton, Ohio) 2025 Aug 22;43(9)
Stem cells (Dayton, Ohio) 2025 Aug 22;43(9)
Fullerenol Doped Matrigel Promotes Maturation of Intestinal Organoids by Inhibiting Oxidative Stress and Apoptosis.
Ruan F, Li L, Wu M, Xue F, Fu Z, Zhang F, Zuo Z, Bu L, Zeng F, He C
ACS applied bio materials 2025 Aug 18;8(8):7161-7170
ACS applied bio materials 2025 Aug 18;8(8):7161-7170
Synergizing adaptive immunity and regenerative signals to enhance osteochondral defects repair.
Lin C, Ying C, Xu Y, Zou Y, Chen R, Xu K, Ji X, Cao Q, Weng J, Jiang L, Ye C, Xu K, He Y, Li W, Wu L, Ran J, Xiong Y, Yu X, Bao J
Bioactive materials 2025 Apr;46:242-258
Bioactive materials 2025 Apr;46:242-258
Lycium-Barbarum Polysaccharide-Loaded Dual-Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species.
Zhong W, Liao W, Xu L, He N, Xu K, Liu C, Wang F, Zhang W, Hu J, Cui H
Advanced healthcare materials 2025 Apr;14(11):e2404741
Advanced healthcare materials 2025 Apr;14(11):e2404741
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Chen K, Yu Y, Wang Y, Zhu Y, Qin C, Xu J, Zou X, Tao T, Li Y, Jiang Y
Drug design, development and therapy 2024;18:259-275
Drug design, development and therapy 2024;18:259-275
Promoting chondrogenesis by targeted delivery to the degenerating cartilage in early treatment of osteoarthritis.
Fei Y, Li X, Lv Z, Liu Z, Xie Y, Chen J, Li W, Liu X, Guo H, Liu H, Zhang Z, Wang X, Fan J, Hu C, Jin X, Jiang R, Xu N, Xia J, Li Y, Shi D
Bioactive materials 2024 Oct;40:624-633
Bioactive materials 2024 Oct;40:624-633
Enhancing long-segmental tracheal restoration: A self-repairing hydrogel loaded with chondrocytokines for sutureless anastomosis and cartilage regeneration.
Guo L, Liu X, Wang Y, Yi J, Li J, Xu Y, Cai K, Dai W, Feng Q, Tao B
Materials today. Bio 2024 Oct;28:101208
Materials today. Bio 2024 Oct;28:101208
Therapeutic framework nucleic acid complexes targeting oxidative stress and pyroptosis for the treatment of osteoarthritis.
Li J, Li Y, Shang X, Xu S, Zhang Z, Xu S, Wang X, Shen M
Materials today. Bio 2024 Oct;28:101202
Materials today. Bio 2024 Oct;28:101202
Cyclic negative pressure promotes chondrocyte growth: Association of IGF-2 with EGR-1.
Li X, Huang L, Liu B, Zhang Z, Zhou G, Guo Z, Song J, Wang X
Biomolecules & biomedicine 2024 Oct 17;24(6):1761-1775
Biomolecules & biomedicine 2024 Oct 17;24(6):1761-1775
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Li J, Zhang SX, Wang DL, Qi JJ, Bai CY, Sun H, Sun BX, Liang S
Theriogenology 2024 Oct 1;227:1-8
Theriogenology 2024 Oct 1;227:1-8
Differential impact of chronic intermittent hypoxia and stress changes on condylar development.
Liu F, Qin L, Zhang K, Yuan F, Zeng X, Zhao Y
Archives of oral biology 2024 Nov;167:106051
Archives of oral biology 2024 Nov;167:106051
Tetrahedral Framework Nucleic Acid-Based Delivery of Astaxanthin Suppresses Chondrocyte Pyroptosis and Modulates Oxidative Stress for the Treatment of Osteoarthritis.
Li Y, Li J, Xu S, Li D, Zhang Z, Huang Q, Wang X, Shen M, Xu S
Advanced healthcare materials 2024 Nov;13(28):e2401452
Advanced healthcare materials 2024 Nov;13(28):e2401452
RIP1 inhibition reduces chondrocyte apoptosis through downregulating nuclear factor-kappa B signaling in a mouse osteoarthritis model.
Zhao H, Wang C, Liu B, Weng Z, Shi Y, Zhang C
Molecular biology reports 2024 Nov 8;51(1):1132
Molecular biology reports 2024 Nov 8;51(1):1132
Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1.
Lin R, Yin J, Huang J, Zou L, Liu L, Tang W, Zhang H, Yang L, Zhang Y, Li G, Wang G, Cai D, Zhang H, Liu Y, Shao Y
Cell death discovery 2024 May 8;10(1):223
Cell death discovery 2024 May 8;10(1):223
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Yu FF, Yu SY, Sun L, Zuo J, Luo KT, Wang M, Fu XL, Zhang F, Huang H, Zhou GY, Wang YJ, Ba Y
Journal of hazardous materials 2024 Mar 5;465:133090
Journal of hazardous materials 2024 Mar 5;465:133090
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Wu X, Fu Y, Ma J, Li C, He A, Zhang T
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Single-cell transcriptomic insights into chemotherapy-induced remodeling of the osteosarcoma tumor microenvironment.
Zheng X, Wu W, Zhao Z, Zhang X, Yu S
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
Journal of cancer research and clinical oncology 2024 Jul 20;150(7):356
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Liu Y, Zhou C, Tan J, Wu T, Pan C, Liu J, Cheng X
Chemical biology & drug design 2024 Jan;103(1):e14382
Chemical biology & drug design 2024 Jan;103(1):e14382
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology.
Tang S, Yao L, Ruan J, Kang J, Cao Y, Nie X, Lan W, Zhu Z, Han W, Liu Y, Tian J, Seale P, Qin L, Ding C
Science translational medicine 2024 Jan 24;16(731):eadf4590
Science translational medicine 2024 Jan 24;16(731):eadf4590
Enhanced therapeutic potential of a self-healing hyaluronic acid hydrogel for early intervention in osteoarthritis.
Wu D, Yang S, Gong Z, Zhu X, Hong J, Wang H, Xu W, Lai J, Wang X, Lu J, Fang X, Jiang G, Zhu J
Materials today. Bio 2024 Dec;29:101353
Materials today. Bio 2024 Dec;29:101353
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Guo Y, Wang P, Hu B, Wang L, Zhang Y, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):112948
International immunopharmacology 2024 Dec 5;142(Pt A):112948
True-bone-ceramics / type I collagen scaffolds for repairing osteochondral defect.
Jiang Y, Li T, Lou Y, Liu B, Liu Y, Li T, Zhang D
Journal of materials science. Materials in medicine 2024 Dec 30;36(1):1
Journal of materials science. Materials in medicine 2024 Dec 30;36(1):1
Wedelolactone alleviates inflammation and cartilage degeneration by suppressing the NF-κB signaling pathway in osteoarthritis.
Sun W, Yue J, Cui Y, Feng J, He Q, Liang J, You W, Shi H, Sun W, Yi Q
International immunopharmacology 2024 Dec 25;143(Pt 1):113359
International immunopharmacology 2024 Dec 25;143(Pt 1):113359
Targeted lipid nanoparticles distributed in hydrogel treat osteoarthritis by modulating cholesterol metabolism and promoting endogenous cartilage regeneration.
Zhao Z, Wang P, Li Z, Wei X, Li S, Lu X, Dai S, Huang B, Man Z, Li W
Journal of nanobiotechnology 2024 Dec 20;22(1):786
Journal of nanobiotechnology 2024 Dec 20;22(1):786
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
Park J, Wu J, Szkop KJ, Jeong J, Jovanovic P, Husmann D, Flores NM, Francis JW, Chen YC, Benitez AM, Zahn E, Song S, Ajani JA, Wang L, Singh K, Larsson O, Garcia BA, Topisirovic I, Gozani O, Mazur PK
Nature 2024 Aug;632(8025):656-663
Nature 2024 Aug;632(8025):656-663
Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway.
Liu D, Yuan L, Xu F, Ma Y, Zhang H, Jin Y, Chen M, Zhang Z, Luo S
Communications biology 2024 Aug 20;7(1):1022
Communications biology 2024 Aug 20;7(1):1022
4-Octyl itaconate protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by inhibiting GPX4 methylation in osteoarthritis.
Pan X, Kong X, Feng Z, Jin Z, Wang M, Lu H, Chen G
International immunopharmacology 2024 Aug 20;137:112531
International immunopharmacology 2024 Aug 20;137:112531
Long noncoding RNA UCA1 promotes the chondrogenic differentiation of human bone marrow mesenchymal stem cells via regulating PARP1 ubiquitination.
Shu T, Li J, Gu J, Wu L, Xie P, Zhang D, Li W, Wan J, Zheng X
Stem cells (Dayton, Ohio) 2024 Aug 1;42(8):752-762
Stem cells (Dayton, Ohio) 2024 Aug 1;42(8):752-762
Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via upregulating SLC40A1.
Chen J, Yang X, Li Q, Ma J, Li H, Wang L, Chen Z, Quan Z
Free radical biology & medicine 2024 Aug 1;220:139-153
Free radical biology & medicine 2024 Aug 1;220:139-153
Injectable silk fibroin peptide nanofiber hydrogel composite scaffolds for cartilage regeneration.
Wu D, Li J, Wang C, Su Z, Su H, Chen Y, Yu B
Materials today. Bio 2024 Apr;25:100962
Materials today. Bio 2024 Apr;25:100962
Curcumin Ameliorates Age-Induced Tight Junction Impaired in Porcine Sertoli Cells by Inactivating the NLRP3 Inflammasome through the AMPK/SIRT3/SOD2/mtROS Signaling Pathway.
Xiao L, Fang Z, Wang Q, Sheng X, Qi X, Xing K, Guo Y, Ni H, Wang X, Zhang Y
Oxidative medicine and cellular longevity 2023;2023:1708251
Oxidative medicine and cellular longevity 2023;2023:1708251
Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors.
Smith CA, Humphreys PA, Naven MA, Woods S, Mancini FE, O'Flaherty J, Meng QJ, Kimber SJ
PloS one 2023;18(1):e0280024
PloS one 2023;18(1):e0280024
Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation.
Xu D, Yan S, Jin H, Chen C, Tang X, Wang X, Li Y, Fei F, Yang A
Frontiers in genetics 2023;14:1302351
Frontiers in genetics 2023;14:1302351
Comprehensive analysis, immune, and cordycepin regulation for SOX9 expression in pan-cancers and the matched healthy tissues.
Liu S, Yang L, Fu J, Li T, Zhou B, Wang K, Wei C, Fu J
Frontiers in immunology 2023;14:1149986
Frontiers in immunology 2023;14:1149986
Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.
Li B, Xia Y, Mei S, Ye Z, Song B, Yan X, Lin F, Rao T, Yu W, Mei C, Lv J, Wu M, Mao Z, Zhou X, Cheng F
Theranostics 2023;13(6):1860-1875
Theranostics 2023;13(6):1860-1875
Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.
Hao RC, Li ZL, Wang FY, Tang J, Li PL, Yin BF, Li XT, Han MY, Mao N, Liu B, Ding L, Zhu H
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712
Comprehensive Analysis of the Transcriptome-Wide m(6)A Methylome in Shaziling Pig Testicular Development.
Chen C, Tang X, Yan S, Yang A, Xiang J, Deng Y, Yin Y, Chen B, Gu J
International journal of molecular sciences 2023 Sep 23;24(19)
International journal of molecular sciences 2023 Sep 23;24(19)
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3.
Wan J, Li M, Yuan X, Yu X, Chen A, Shao M, Kang H, Cheng P
International journal of molecular medicine 2023 Oct;52(4)
International journal of molecular medicine 2023 Oct;52(4)
Spatial and Temporal Expression of Ectodysplasin-A Signaling Pathway Members During Mandibular Condylar Development in Postnatal Mice.
Xing L, Liu Y, Wu J, Song C, Jiang B
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Nov;71(11):631-642
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Nov;71(11):631-642
Long non-coding RNA MIR22HG suppresses the chondrogenic differentiation of human adipose-derived stem cells by interacting with CTCF to upregulate CRLF1.
Guo J, Ye W, Wu X, Huang H, Li B, Ren Z, Yang Z
Functional & integrative genomics 2023 Nov 1;23(4):329
Functional & integrative genomics 2023 Nov 1;23(4):329
CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma.
Mijiti M, Maimaiti A, Chen X, Tuersun M, Dilixiati M, Dilixiati Y, Zhu G, Wu H, Li Y, Turhon M, Abulaiti A, Maimaitiaili N, Yiming N, Kasimu M, Wang Y
Molecular medicine (Cambridge, Mass.) 2023 May 14;29(1):64
Molecular medicine (Cambridge, Mass.) 2023 May 14;29(1):64
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159
Regenerative therapy 2023 Mar;22:148-159
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
Yang A, Yan S, Yin Y, Chen C, Tang X, Ran M, Chen B
International journal of molecular sciences 2023 Mar 24;24(7)
International journal of molecular sciences 2023 Mar 24;24(7)
TNF-α activates RELA expression via TNFRSF1B to upregulate OPA1 expression and inhibit chondrogenic differentiation of human adipose stem cells.
Guo J, Ye W, Wu X, Huang H, Li B, Sun Z, Ren Z, Yang Z
Journal of orthopaedic surgery and research 2023 Jun 13;18(1):430
Journal of orthopaedic surgery and research 2023 Jun 13;18(1):430
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Shen PC, Huang SH, Liu ZM, Lu CC, Chou SH, Tien YC
International immunopharmacology 2023 Jul;120:110295
International immunopharmacology 2023 Jul;120:110295
Fibrin glue delivery system containing rhein ameliorates intervertebral disc degeneration by anti-inflammatory efficacy.
Bao J, Gao W, Zhang W, Wang D, Pan H
Journal of orthopaedic surgery and research 2023 Jul 6;18(1):485
Journal of orthopaedic surgery and research 2023 Jul 6;18(1):485
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Dai Z, Xia C, Zhao T, Wang H, Tian H, Xu O, Zhu X, Zhang J, Chen P
Materials today. Bio 2023 Feb;18:100512
Materials today. Bio 2023 Feb;18:100512
Budget-Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient-Derived Colon Organoids.
Rigaux E, Chen JW, George F, Lemaire J, Bertrand C, Faugeras L, Fattaccioli A, Gilliaux Q, D'Hondt L, Michiels C, Renard HF, Zanin N
Current protocols 2023 Dec;3(12):e943
Current protocols 2023 Dec;3(12):e943
MiR-203a-3p attenuates apoptosis and pyroptosis of chondrocytes by regulating the MYD88/NF-κB pathway to alleviate osteoarthritis progression.
Chen J, Liu Z, Sun H, Liu M, Wang J, Zheng C, Cao X
Aging 2023 Dec 13;15(23):14457-14472
Aging 2023 Dec 13;15(23):14457-14472
Growth differentiation factor 5 inhibits lipopolysaccharide-mediated pyroptosis of nucleus pulposus mesenchymal stem cells via RhoA signaling pathway.
Zhu C, Zhou Q, Wang Z, Zhang J, Xu C, Ruan D
Molecular biology reports 2023 Aug;50(8):6337-6347
Molecular biology reports 2023 Aug;50(8):6337-6347
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Zhu C, Zhou Q, Tang L, Xuan A, Xu C, Wang Z, Ruan D
Tissue engineering. Part A 2023 Aug;29(15-16):424-438
Tissue engineering. Part A 2023 Aug;29(15-16):424-438
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice.
Li Z, Chen Z, Chen J, Liu Z, Li Z, Sun H, Wang X, Wei J, Cao X, Zheng D
Chinese medicine 2023 Apr 19;18(1):42
Chinese medicine 2023 Apr 19;18(1):42
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Ma T, Jia L, Zhao J, Lv L, Yu Y, Ruan H, Song X, Chen H, Li X, Zhang J, Gao L
Frontiers in pharmacology 2022;13:1027553
Frontiers in pharmacology 2022;13:1027553
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Shi Y, Shao J, Zhang Z, Zhang J, Lu H
Frontiers in bioengineering and biotechnology 2022;10:1061855
Frontiers in bioengineering and biotechnology 2022;10:1061855
ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H
Environmental toxicology 2022 Sep;37(9):2133-2142
Environmental toxicology 2022 Sep;37(9):2133-2142
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Wang W, Jing X, Du T, Ren J, Liu X, Chen F, Shao Y, Sun S, Yang G, Cui X
Free radical biology & medicine 2022 Sep;190:234-246
Free radical biology & medicine 2022 Sep;190:234-246
MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling.
Zhou X, Luo J, Xie H, Wei Z, Li T, Liu J, Liao X, Zhu G, Peng T
Cell death discovery 2022 Oct 15;8(1):418
Cell death discovery 2022 Oct 15;8(1):418
Dual-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration therapy.
Yang L, Yu C, Fan X, Zeng T, Yang W, Xia J, Wang J, Yao L, Hu C, Jin Y, Zhu Y, Chen J, Hu Z
Journal of nanobiotechnology 2022 Oct 1;20(1):433
Journal of nanobiotechnology 2022 Oct 1;20(1):433
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Xiao L, Wang Z, Lu N, Wei H, Kang J, Yuan M, Sheng X, Qi X, Xing K, Guo Y, Wang X, Zhao J, Gao Y, Ni H
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
Endothelial cell-derived S1P promotes migration and stemness by binding with GPR63 in colorectal cancer.
Zeng S, Liang Y, Hu H, Wang F, Liang L
Pathology, research and practice 2022 Dec;240:154197
Pathology, research and practice 2022 Dec;240:154197
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Xue Y, Luo M, Hu X, Li X, Shen J, Zhu W, Huang L, Hu Y, Guo Y, Liu L, Wang L, Luo S
Communications biology 2022 Dec 1;5(1):1316
Communications biology 2022 Dec 1;5(1):1316
SOX9 negatively regulates the RLR antiviral signaling by targeting MAVS.
Jiang X, Xu LG
Virus genes 2022 Apr;58(2):122-132
Virus genes 2022 Apr;58(2):122-132
Electroacupuncture Upregulates HIF-1α and SOX9 Expression in Knee Osteoarthritis.
Tong J, Deng C, Sun G, Zhou J, Zhong P, Wang T, Zeng Y, Wu Q, Liao Y, Luo F, Peng T, Liao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2047097
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2047097
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
Cheng L, Xie M, Qiao W, Song Y, Zhang Y, Geng Y, Xu W, Wang L, Wang Z, Huang K, Dong N, Sun Y
Communications biology 2021 Sep 6;4(1):1039
Communications biology 2021 Sep 6;4(1):1039
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Gao XX, Liu CH, Hu ZL, Li HY, Chang X, Li YY, Zhang YY, Zhai Y, Li CQ
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
LncRNA NONHSAT030515 promotes the chondrogenic differentiation of human adipose-derived stem cells via regulating the miR-490-5p/BMPR2 axis.
Yang Q, Guo J, Ren Z, Li B, Huang H, Yang Z
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):658
Journal of orthopaedic surgery and research 2021 Nov 6;16(1):658
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits.
Liu H, Rui Y, Liu J, Gao F, Jin Y
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Journal of orthopaedic surgery and research 2021 Nov 3;16(1):657
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
Cao Y, Tang S, Nie X, Zhou Z, Ruan G, Han W, Zhu Z, Ding C
EBioMedicine 2021 Mar;65:103283
EBioMedicine 2021 Mar;65:103283
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Huang H, Liu K, Ou H, Qian X, Wan J
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Zhang Z, Li Z, Wang Y, Wang Q, Yao M, Zhao L, Shi J, Guan F, Ma S
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.
Wang B, Ye Q, Zou C
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
Medical science monitor : international medical journal of experimental and clinical research 2020 Jul 14;26:e923507
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