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Learn13999-1-AP
antibody from Proteintech Group
Targeting: OLIG2
BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [109]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 13999-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13999-1-AP, RRID:AB_2157541
- Product name
- OLIG2 antibody
- Antibody type
- Polyclonal
- Description
- OLIG2 antibody (Cat. #13999-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Stem Cell-Derived Exosomes Improve Neurological Dysfunction in a Rat Model of Moderate-to-Severe Cerebral Palsy.
Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.
Buyang Huanwu decoction promotes post-stroke white matter repair via TREM2-Dependent microglial phagocytosis and IGF1 secretion.
Erk5-mediated microglial ferroptosis drives ischemic white matter damage via the Nfatc4-Clptm1l axis.
Promoting the nuclear retention of HMGB1 attenuates astrocyte senescence.
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling.
Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination.
Generation of spatially patterned human neural tube-like structures using microfluidic gradient devices.
Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq.
A skin-hypothalamus axis couples heat stress and metabolic dysfunction.
Oligodendrocyte arrangement, identification and morphology in the developing superior olivary complex.
Convergent activation of the integrated stress response and ER-mitochondria uncoupling in VAPB-associated ALS.
Electroacupuncture promotes myelin repair in the corpus callosum region of cerebral ischemic rats by modulating microglia activation and polarization.
Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages.
Transient gene melting governs the timing of oligodendrocyte maturation.
Sex-dependent impairments in oligodendrocyte maturation and myelination in offspring mice exposed to preeclampsia.
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
High-grade astrocytoma in a sheep: clinical, pathology, and genetic investigations.
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Edaravone protects against cuprizone-induced demyelination in rats by modulating TNF-α/NF-ĸB/NLRP3 signaling and the kynurenine pathway.
Deferiprone promoted remyelination and functional recovery through enhancement of oligodendrogenesis in experimental demyelination animal model.
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes.
Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex.
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Expression Analyses of C-Terminal-Binding Protein 1 (CtBP1) during Mouse Brain Development.
Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease.
AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice.
Acetate enables metabolic fitness and cognitive performance during sleep disruption.
Small Molecule Hydrogels Loading Small Molecule Drugs from Chinese Medicine for the Enhanced Treatment of Traumatic Brain Injury.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer's disease.
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding.
Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis.
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Disruption of the Na(+)/K(+)-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Lycium barbarum glycopeptide ameliorates motor and visual deficits in autoimmune inflammatory diseases.
Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease.
EAAT3 impedes oligodendrocyte remyelination in chronic cerebral hypoperfusion-induced white matter injury.
Astragalus polysaccharides promote neural stem cells-derived oligodendrogenesis through attenuating CD8(+)T cell infiltration in experimental autoimmune encephalomyelitis.
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Oxygen-Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes.
Bruton's tyrosine kinase inhibition ameliorated neuroinflammation during chronic white matter ischemia.
Unveiling the role of TAGLN2 in glioblastoma: From proneural-mesenchymal transition to Temozolomide resistance.
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome.
Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation.
Trem2 deficiency attenuates microglial phagocytosis and autophagic-lysosomal activation in white matter hypoperfusion.
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis.
Identification of Tau protein as a novel marker for maturation and pathological changes of oligodendrocytes.
XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors.
Tetrahydrofolate Alleviates the Inhibitory Effect of Oxidative Stress on Neural Stem Cell Proliferation through PTEN/Akt/mTOR Pathway.
PTBP-1 and TNF-α/NF-κB are involved in repair mechanisms of human umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury.
Clemastine Promotes Differentiation of Oligodendrocyte Progenitor Cells Through the Activation of ERK1/2 via Muscarinic Receptors After Spinal Cord Injury.
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Bovine intracranial neoplasia: A retrospective case series.
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood-brain barrier in rodents and primates.
The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis.
Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay.
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain.
TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway.
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function.
Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation.
Phospholipase D and phosphatidylinositol-4-phosphate 5-kinase 1 are involved in the regulation of oligodendrocyte morphological differentiation.
ADAM10 suppresses demyelination and reduces seizure susceptibility in cuprizone-induced demyelination model.
Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.
Valproic Acid Enhances Reprogramming Efficiency and Neuronal Differentiation on Small Molecules Staged-Induction Neural Stem Cells: Suggested Role of mTOR Signaling.
Myelin Damage in Diffuse Axonal Injury.
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
Distribution of endogenous normal tau in the mouse brain.
Examining the role of the surfactant family member SFTA3 in interneuron specification.
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells.
Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats.
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Poly-L-ornithine enhances migration of neural stem/progenitor cells via promoting α-Actinin 4 binding to actin filaments.
Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells.
Resetting cancer stem cell regulatory nodes upon MYC inhibition.
Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway.
Neuropeptide Y has a protective role during murine retrovirus-induced neurological disease.
Peng T Jr, Lin H, Zeng X, Xie Y, Luo J, Zhang L, Huang S, Ye Z, Guo X, Le W, Zhang M, Li W, Peng T Sr, Liu L, Han M, Gao T, Tang H, Zhang J, He L, Xu K
Stem cell reviews and reports 2026 May;22(4):1865-1885
Stem cell reviews and reports 2026 May;22(4):1865-1885
Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.
Liu LL, Shannahan J, Zheng W
Fluids and barriers of the CNS 2026 Mar 31;23(1)
Fluids and barriers of the CNS 2026 Mar 31;23(1)
Buyang Huanwu decoction promotes post-stroke white matter repair via TREM2-Dependent microglial phagocytosis and IGF1 secretion.
Qin X, Zhang Y, Liu J, Xiao G, Guo Y, Deng H, Hao H, Xu W, Cheng X, Zhao L, Xu S
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120520
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120520
Erk5-mediated microglial ferroptosis drives ischemic white matter damage via the Nfatc4-Clptm1l axis.
Chu YH, Zhang LY, He JY, Wang YF, Dong MH, You YF, Pang XW, Zhu LF, Zhang H, Xu LL, Chen L, Zhou LQ, Xiao J, Shang K, Gong JK, Wang W, Tian DS, Qin C
Proceedings of the National Academy of Sciences of the United States of America 2026 Jan 13;123(2):e2521757123
Proceedings of the National Academy of Sciences of the United States of America 2026 Jan 13;123(2):e2521757123
Promoting the nuclear retention of HMGB1 attenuates astrocyte senescence.
Zhang N, Yang F, Shi J, Tang X, Fan A, Li W, Zhang F, Chai S, Chen Q, Wang C, Xu Y, Gong F, Lu Y, Zheng F
Journal of neuroinflammation 2026 Jan 12;23(1):55
Journal of neuroinflammation 2026 Jan 12;23(1):55
HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma.
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z
Cell death & disease 2026 Feb 7;17(1):208
Cell death & disease 2026 Feb 7;17(1):208
Activation status of astrocytes drives the MS/NMOSD therapeutic paradox: Insights from IFNAR1 signaling.
Dai L, Cheng G, Cui T, He S, Wang R, Kang J, Li P, Zhang X, Ding X, Xue X, Yang L, Zhang Y, Yan Y
Cell reports 2026 Feb 24;45(2):116913
Cell reports 2026 Feb 24;45(2):116913
Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination.
Yan W, Xiang D, Du L, Zhu D, Jia Q, Liu Y, Wang S, Liu L, Guan H, Zhao Y, Jiang G, Gao S, Wang H
iScience 2026 Feb 20;29(2):114718
iScience 2026 Feb 20;29(2):114718
Generation of spatially patterned human neural tube-like structures using microfluidic gradient devices.
Xue X, Rahman OM, Sun S, Bok J, Tang A, Fu J
Nature protocols 2026 Apr;21(4):1730-1753
Nature protocols 2026 Apr;21(4):1730-1753
Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq.
Zhang L, Ma Q, Kong X, Zou W, Wang B, Wu B, Cai S, Bai T, Tan R, Dai Z, Liu X, Jia Z, Zhang M, Li T, Zheng Y, Hu X, Wu J, Xu Z, Zhou H
Science (New York, N.Y.) 2026 Apr 23;392(6796):eadw2156
Science (New York, N.Y.) 2026 Apr 23;392(6796):eadw2156
A skin-hypothalamus axis couples heat stress and metabolic dysfunction.
Zhou HY, Feng X, Wen J, Xiao Y, Wang LW, Chen LY, Xie GQ, Zhao JJ, Huang Y, Luo XH
Cell 2026 Apr 21;
Cell 2026 Apr 21;
Oligodendrocyte arrangement, identification and morphology in the developing superior olivary complex.
Zacher AC, Grabinski M, Console-Meyer L, Felmy F, Pätz-Warncke C
Frontiers in cellular neuroscience 2025;19:1561312
Frontiers in cellular neuroscience 2025;19:1561312
Convergent activation of the integrated stress response and ER-mitochondria uncoupling in VAPB-associated ALS.
Landry C, Costanzo JP, Mitne-Neto M, Zatz M, Schaffer AE, Hatzoglou M, Muotri AR, Miranda HC
EMBO molecular medicine 2025 Sep;17(9):2299-2331
EMBO molecular medicine 2025 Sep;17(9):2299-2331
Electroacupuncture promotes myelin repair in the corpus callosum region of cerebral ischemic rats by modulating microglia activation and polarization.
Wang W, Chan C, Wang X, Wu F
Neurological research 2025 Sep 9;:1-12
Neurological research 2025 Sep 9;:1-12
Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages.
Gu D, Hu L, Yang K, Yuan W, Shan D, Gao J, Li J, Gimple RC, Dixit D, Zhu Z, Li D, Wu Q, Shi Z, Wang Y, Zhao N, Yang K, Shao J, Lin F, Wang Q, Jin G, Chen Y, Qian X, Hu Z, Li C, Zhang N, You Y, Liu J, Zhang Q, Zhang J, Rich JN, Wang X
Developmental cell 2025 Oct 6;60(19):2558-2575.e6
Developmental cell 2025 Oct 6;60(19):2558-2575.e6
Transient gene melting governs the timing of oligodendrocyte maturation.
Allan KC, Zhan JJ, Morton AR, Cohn EF, Scavuzzo MA, Nikhil A, Elitt MS, Clayton BLL, Hu LR, Shick HE, Vrabic JK, Olsen HE, Factor DC, Henninger JE, Bachmann G, Powers BE, Young RA, Lin CY, Scacheri PC, Miller TE, Tesar PJ
Cell 2025 Oct 30;188(22):6205-6219.e23
Cell 2025 Oct 30;188(22):6205-6219.e23
Sex-dependent impairments in oligodendrocyte maturation and myelination in offspring mice exposed to preeclampsia.
Wu Z, Qiu Y, Chen X, Xia Z, Lv J, Jia Y, Xue H, Zhao P
Experimental neurology 2025 Nov;393:115405
Experimental neurology 2025 Nov;393:115405
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Liu M, Yang L, Yan Z, Huang Y
Cellular signalling 2025 Nov;135:112046
Cellular signalling 2025 Nov;135:112046
Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.
Li J, Tang C, Zhang X, Xing R, Guo Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e03897
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
Tang C, Ding Y, Yang S, Lei X, Zhang M, Xu B, He D
Molecular neurobiology 2025 Nov 22;63(1):133
Molecular neurobiology 2025 Nov 22;63(1):133
High-grade astrocytoma in a sheep: clinical, pathology, and genetic investigations.
Mignacca SA, Konold T, Gallisai E, Maestrale C, Gomez-Vitores A, Nunez A
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2025 May;37(3):499-503
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2025 May;37(3):499-503
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
Malik V, Huang X, Zhou H, Bojar R, Soni RK, Landry DW, Jelic S, Wang J
iScience 2025 May 16;28(5):112510
iScience 2025 May 16;28(5):112510
Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Glia 2025 Jun;73(6):1221-1240
Glia 2025 Jun;73(6):1221-1240
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
Li X, Zhang J, Zhang Y, Guo L, Gao M, Wang Y, Qiu W, Yuan Y, Zhu J, Liu B, Xiong H, Xu T, Xu R
Materials today. Bio 2025 Jun;32:101639
Materials today. Bio 2025 Jun;32:101639
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Edaravone protects against cuprizone-induced demyelination in rats by modulating TNF-α/NF-ĸB/NLRP3 signaling and the kynurenine pathway.
Mahmoud AMA, Helal MG, El-Sherbiny M, Said E, Nader MA, Shehatou GSG
European journal of pharmacology 2025 Jul 15;999:177686
European journal of pharmacology 2025 Jul 15;999:177686
Deferiprone promoted remyelination and functional recovery through enhancement of oligodendrogenesis in experimental demyelination animal model.
Rayatpour A, Foolad F, Javan M
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jan;398(1):715-727
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jan;398(1):715-727
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes.
Liu SS, Zha Z, Li C, Li CY, Wang L
Journal of ethnopharmacology 2025 Jan 31;340:119283
Journal of ethnopharmacology 2025 Jan 31;340:119283
Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex.
Alawathugoda TT, Sheikh MA, Challagandla AK, Dheen ST, Emerald BS, Ansari SA
The Journal of biological chemistry 2025 Feb;301(2):108173
The Journal of biological chemistry 2025 Feb;301(2):108173
The foam cell-derived exosomes exacerbate ischemic white matter injury via transmitting metabolic defects to microglia.
Zhang H, Zhou LQ, Yang S, Dong MH, Chen L, Lu YL, Zhang LY, Zhang L, Chu YH, Xu LL, Pang XW, Zhu LF, Xu T, Yong TY, Wang W, Tian DS, Qin C
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
Cell metabolism 2025 Aug 5;37(8):1636-1654.e10
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
Expression Analyses of C-Terminal-Binding Protein 1 (CtBP1) during Mouse Brain Development.
Hamada N, Matsuki T, Iwamoto I, Nishijo T, Noda M, Tabata H, Nakayama A, Nagata KI
Developmental neuroscience 2024;46(4):262-272
Developmental neuroscience 2024;46(4):262-272
Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease.
Evans LMP, Gawron J, Sim FJ, Feltri ML, Marziali LN
PloS one 2024;19(12):e0314858
PloS one 2024;19(12):e0314858
AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice.
Chauhan M, Daugherty AL, Khadir FE, Duzenli OF, Hoffman A, Tinklenberg JA, Kang PB, Aslanidi G, Pacak CA
Journal of translational medicine 2024 Sep 5;22(1):824
Journal of translational medicine 2024 Sep 5;22(1):824
Acetate enables metabolic fitness and cognitive performance during sleep disruption.
He Q, Ji L, Wang Y, Zhang Y, Wang H, Wang J, Zhu Q, Xie M, Ou W, Liu J, Tang K, Lu K, Liu Q, Zhou J, Zhao R, Cai X, Li N, Cao Y, Li T
Cell metabolism 2024 Sep 3;36(9):1998-2014.e15
Cell metabolism 2024 Sep 3;36(9):1998-2014.e15
Small Molecule Hydrogels Loading Small Molecule Drugs from Chinese Medicine for the Enhanced Treatment of Traumatic Brain Injury.
Luo W, Yang Z, Zheng J, Cai Z, Li X, Liu J, Guo X, Luo M, Fan X, Cheng M, Tang T, Liu J, Wang Y
ACS nano 2024 Oct 22;18(42):28894-28909
ACS nano 2024 Oct 22;18(42):28894-28909
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer's disease.
Ishii A, Pathoulas JA, MoustafaFathy Omar O, Ge Y, Yao AY, Pantalena T, Singh N, Zhou J, He W, Murphy P, Yan R, Hu X
Molecular neurodegeneration 2024 Nov 16;19(1):83
Molecular neurodegeneration 2024 Nov 16;19(1):83
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding.
Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB
Nature neuroscience 2024 May;27(5):822-835
Nature neuroscience 2024 May;27(5):822-835
Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis.
Landry C, Costanzo J, Mitne-Neto M, Zatz M, Schaffer A, Hatzoglou M, Muotri A, Miranda HC
bioRxiv : the preprint server for biology 2024 May 14;
bioRxiv : the preprint server for biology 2024 May 14;
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Hou B, Yin J, Liu S, Guo J, Zhang B, Zhang Z, Yang L, Tan X, Long Y, Feng S, Zhou J, Wu Y, Wang X, Han S, Wang Z, He X
Molecular neurobiology 2024 Mar;61(3):1318-1330
Molecular neurobiology 2024 Mar;61(3):1318-1330
Disruption of the Na(+)/K(+)-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Huang S, Dong W, Lin X, Xu K, Li K, Xiong S, Wang Z, Nie X, Bian JS
Immunity 2024 Mar 12;57(3):495-512.e11
Immunity 2024 Mar 12;57(3):495-512.e11
Exogenous NADPH could mitigate pyroptosis-induced brain injury in fetal mice exposed to gestational intermittent hypoxia.
Wei J, Zheng W, Teng C, An X, Li L, Zhong P, Peng C, Zhuge S, Akoto Ampadu J, Yu C, Cai X
International immunopharmacology 2024 Jun 30;135:112311
International immunopharmacology 2024 Jun 30;135:112311
Lycium barbarum glycopeptide ameliorates motor and visual deficits in autoimmune inflammatory diseases.
Xu L, Yang L, Xu H, Li Y, Peng F, Qiu W, Tang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155610
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155610
Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease.
Evans LMP, Gawron J, Sim FJ, Feltri ML, Marziali LN
bioRxiv : the preprint server for biology 2024 Jul 23;
bioRxiv : the preprint server for biology 2024 Jul 23;
EAAT3 impedes oligodendrocyte remyelination in chronic cerebral hypoperfusion-induced white matter injury.
Zhang Y, Ya D, Yang J, Jiang Y, Li X, Wang J, Tian N, Deng J, Yang B, Li Q, Liao R
CNS neuroscience & therapeutics 2024 Jan;30(1):e14487
CNS neuroscience & therapeutics 2024 Jan;30(1):e14487
Astragalus polysaccharides promote neural stem cells-derived oligodendrogenesis through attenuating CD8(+)T cell infiltration in experimental autoimmune encephalomyelitis.
Zhao Y, Ma J, Ding G, Wang Y, Yu H, Cheng X
International immunopharmacology 2024 Jan 5;126:111303
International immunopharmacology 2024 Jan 5;126:111303
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444
Bioactive materials 2024 Feb;32:427-444
Oxygen-Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes.
Moriyama K, Horino A, Kohyama K, Nishito Y, Morio T, Sakuma H
Brain sciences 2024 Feb 29;14(3)
Brain sciences 2024 Feb 29;14(3)
Bruton's tyrosine kinase inhibition ameliorated neuroinflammation during chronic white matter ischemia.
Xu LL, Yang S, Zhou LQ, Chu YH, Pang XW, You YF, Zhang H, Zhang LY, Zhu LF, Chen L, Shang K, Xiao J, Wang W, Tian DS, Qin C
Journal of neuroinflammation 2024 Aug 3;21(1):195
Journal of neuroinflammation 2024 Aug 3;21(1):195
Unveiling the role of TAGLN2 in glioblastoma: From proneural-mesenchymal transition to Temozolomide resistance.
Li Y, Wang X, Xu T, Xu F, Chen T, Li Z, Wang Y, Chen H, Ming J, Cai J, Jiang C, Meng X
Cancer letters 2024 Aug 28;598:217107
Cancer letters 2024 Aug 28;598:217107
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome.
Ahuja K, Vandenabeele M, Nami F, Lefevere E, Van Hoecke J, Bergmans S, Claes M, Vervliet T, Neyrinck K, Burg T, De Herdt D, Bhaskar P, Zhu Y, Looser ZJ, Loncke J, Gsell W, Plaas M, Agostinis P, Swinnen JV, Van Den Bosch L, Bultynck G, Saab AS, Wolfs E, Chai YC, Himmelreich U, Verfaillie C, Moons L, De Groef L
Acta neuropathologica communications 2024 Aug 28;12(1):140
Acta neuropathologica communications 2024 Aug 28;12(1):140
Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation.
Wen Q, Zhou J, Tian C, Li X, Song G, Gao Y, Sun Y, Ma C, Yao S, Liang X, Kang X, Wang N, Yao Y, Wang H, Liang X, Tang J, Offer SM, Lei X, Yu C, Liu X, Liu Z, Wang Z, Gan H
Nature genetics 2023 Sep;55(9):1555-1566
Nature genetics 2023 Sep;55(9):1555-1566
Trem2 deficiency attenuates microglial phagocytosis and autophagic-lysosomal activation in white matter hypoperfusion.
Pang XW, Chu YH, Zhou LQ, Chen M, You YF, Tang Y, Yang S, Zhang H, Xiao J, Deng G, Wang W, Shang K, Qin C, Tian DS
Journal of neurochemistry 2023 Nov;167(4):489-504
Journal of neurochemistry 2023 Nov;167(4):489-504
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301
Behavioural brain research 2023 Mar 28;442:114301
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Liu LL, Shannahan J, Zheng W
bioRxiv : the preprint server for biology 2023 Mar 18;
bioRxiv : the preprint server for biology 2023 Mar 18;
Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
Dai L, Gao F, Wang Q, Lv X, Cheng Z, Wu Y, Chai X, Zetterberg H, Blennow K, Levey AI, Shi J, Shen Y, CANDI Consortium
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559
Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation.
Luo W, Xu H, Xu L, Jiang W, Chen C, Chang Y, Liu C, Tian Z, Qiu X, Xie C, Li X, Chen H, Lai S, Wu L, Cui Y, Tang C, Qiu W
Glia 2023 Feb;71(2):284-304
Glia 2023 Feb;71(2):284-304
Rapamycin Exerts an Antidepressant Effect and Enhances Myelination in the Prefrontal Cortex of Chronic Restraint Stress Mice.
Zhang J, Li W, Yue Q, Liu L, Hou ST, Ju J
Neuroscience 2023 Dec 15;535:99-107
Neuroscience 2023 Dec 15;535:99-107
NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis.
Wang H, Zhao P, Zhang Y, Chen Z, Bao H, Qian W, Wu J, Xing Z, Hu X, Jin K, Zhuge Q, Yang J
Cell death discovery 2023 Aug 15;9(1):297
Cell death discovery 2023 Aug 15;9(1):297
Identification of Tau protein as a novel marker for maturation and pathological changes of oligodendrocytes.
Torii T, Miyamoto Y, Nakata R, Higashi Y, Shinmyo Y, Kawasaki H, Miyasaka T, Misonou H
Glia 2023 Apr;71(4):1002-1017
Glia 2023 Apr;71(4):1002-1017
XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors.
Bery A, Etienne O, Mouton L, Mokrani S, Granotier-Beckers C, Gauthier LR, Feat-Vetel J, Kortulewski T, Pérès EA, Desmaze C, Lestaveal P, Barroca V, Laugeray A, Boumezbeur F, Abramovski V, Mortaud S, Menuet A, Le Bihan D, Villartay JP, Boussin FD
Cell reports 2023 Apr 25;42(4):112342
Cell reports 2023 Apr 25;42(4):112342
Tetrahydrofolate Alleviates the Inhibitory Effect of Oxidative Stress on Neural Stem Cell Proliferation through PTEN/Akt/mTOR Pathway.
Zhang X, Liu Z, Yang W, Zhao F, Zhang C, Feng H, Zhou T, Zhong J, Zou Y, Feng H, Ge H, Hu R
Oxidative medicine and cellular longevity 2022;2022:9021474
Oxidative medicine and cellular longevity 2022;2022:9021474
PTBP-1 and TNF-α/NF-κB are involved in repair mechanisms of human umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury.
Cao H, Ji X, Wang Q, Guan X, Wei W, Li Y, Zou W, Liu J
American journal of translational research 2022;14(7):4443-4456
American journal of translational research 2022;14(7):4443-4456
Clemastine Promotes Differentiation of Oligodendrocyte Progenitor Cells Through the Activation of ERK1/2 via Muscarinic Receptors After Spinal Cord Injury.
Tong LY, Deng YB, Du WH, Zhou WZ, Liao XY, Jiang X
Frontiers in pharmacology 2022;13:914153
Frontiers in pharmacology 2022;13:914153
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Ge Y, Zhen F, Liu Z, Feng Z, Wang G, Zhang C, Wang X, Sun Y, Zheng X, Bai Y, Yao R
Frontiers in pharmacology 2022;13:766744
Frontiers in pharmacology 2022;13:766744
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Bovine intracranial neoplasia: A retrospective case series.
Jahns H, McElroy MC
Veterinary pathology 2022 Sep;59(5):824-835
Veterinary pathology 2022 Sep;59(5):824-835
Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo.
Zhu Y, Chen M, Zhang Y, Han M
International journal of molecular sciences 2022 Sep 15;23(18)
International journal of molecular sciences 2022 Sep 15;23(18)
Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood-brain barrier in rodents and primates.
Yao Y, Wang J, Liu Y, Qu Y, Wang K, Zhang Y, Chang Y, Yang Z, Wan J, Liu J, Nakashima H, Lawler SE, Chiocca EA, Cho CF, Bei F
Nature biomedical engineering 2022 Nov;6(11):1257-1271
Nature biomedical engineering 2022 Nov;6(11):1257-1271
The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.
Sui A, Han B, Ren W, He W, Gao C, Han X, Liu S, Zhang Y, Qi X, Guo X
Journal of molecular neuroscience : MN 2022 May;72(5):939-946
Journal of molecular neuroscience : MN 2022 May;72(5):939-946
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Wang T, Xu J, Xu Y, Xiao J, Bi N, Gu X, Wang HL
Cell reports 2022 Mar 8;38(10):110478
Cell reports 2022 Mar 8;38(10):110478
Matrine inhibits the Wnt3a/β-catenin/TCF7L2 signaling pathway in experimental autoimmune encephalomyelitis.
Ma R, Chu Y, Dou M, Jing Y, Zhao X, Li X, Li S, Zhang Y, Wang L, Zhu L
Journal of neuroimmunology 2022 Jun 15;367:577876
Journal of neuroimmunology 2022 Jun 15;367:577876
Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration.
Kreher C, Favret J, Weinstock NI, Maulik M, Hong X, Gelb MH, Wrabetz L, Feltri ML, Shin D
PLoS biology 2022 Jul;20(7):e3001661
PLoS biology 2022 Jul;20(7):e3001661
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay.
Martin S, Allan KC, Pinkard O, Sweet T, Tesar PJ, Coller J
Nature communications 2022 Aug 25;13(1):5003
Nature communications 2022 Aug 25;13(1):5003
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
LaForce GR, Farr JS, Liu J, Akesson C, Gumus E, Pinkard O, Miranda HC, Johnson K, Sweet TJ, Ji P, Lin A, Coller J, Philippidou P, Wagner EJ, Schaffer AE
Neuron 2022 Apr 20;110(8):1340-1357.e7
Neuron 2022 Apr 20;110(8):1340-1357.e7
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Tian Y, He M, Pan L, Yuan X, Xiong M, Meng L, Yao Z, Yu Z, Ye K, Zhang Z
Frontiers in aging neuroscience 2021;13:760781
Frontiers in aging neuroscience 2021;13:760781
Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.
Creighton BA, Afriyie S, Ajit D, Casingal CR, Voos KM, Reger J, Burch AM, Dyne E, Bay J, Huang JK, Anton ES, Fu MM, Lorenzo DN
eLife 2021 Nov 23;10
eLife 2021 Nov 23;10
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination.
Shen K, Reichelt M, Kyauk RV, Ngu H, Shen YA, Foreman O, Modrusan Z, Friedman BA, Sheng M, Yuen TJ
Cell reports 2021 Mar 9;34(10):108835
Cell reports 2021 Mar 9;34(10):108835
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain.
Mathieu C, Bovier FT, Ferren M, Lieberman NAP, Predella C, Lalande A, Peddu V, Lin MJ, Addetia A, Patel A, Outlaw V, Corneo B, Dorrello NV, Briese T, Hardie D, Horvat B, Moscona A, Greninger AL, Porotto M
mBio 2021 Jun 29;12(3):e0079921
mBio 2021 Jun 29;12(3):e0079921
TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway.
Ruganzu JB, Zheng Q, Wu X, He Y, Peng X, Jin H, Zhou J, Ma R, Ji S, Ma Y, Qian Y, Wang Y, Yang W
Experimental neurology 2021 Feb;336:113506
Experimental neurology 2021 Feb;336:113506
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function.
Allan KC, Hu LR, Scavuzzo MA, Morton AR, Gevorgyan AS, Cohn EF, Clayton BLL, Bederman IR, Hung S, Bartels CF, Madhavan M, Tesar PJ
Cell stem cell 2021 Feb 4;28(2):257-272.e11
Cell stem cell 2021 Feb 4;28(2):257-272.e11
Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation.
Liang L, Zeng T, Zhao Y, Lu R, Guo B, Xie R, Tang W, Zhang L, Mao Z, Yang X, Wu S, Wang Y, Zhang H
Journal of pineal research 2021 Dec;71(4):e12771
Journal of pineal research 2021 Dec;71(4):e12771
Phospholipase D and phosphatidylinositol-4-phosphate 5-kinase 1 are involved in the regulation of oligodendrocyte morphological differentiation.
Kato Y, Ochiai A, Seki Y, Morimoto T, Oizumi H, Ohbuchi K, Mizoguchi K, Yamamoto M, Sakagami H, Miyamoto Y, Yamauchi J
Experimental cell research 2021 Aug 1;405(1):112654
Experimental cell research 2021 Aug 1;405(1):112654
ADAM10 suppresses demyelination and reduces seizure susceptibility in cuprizone-induced demyelination model.
Zhu X, Yao Y, Yang J, Zhang C, Li X, Zhang A, Liu X, Zhang C, Gan G
Free radical biology & medicine 2021 Aug 1;171:26-41
Free radical biology & medicine 2021 Aug 1;171:26-41
Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions.
Du Y, Song Y, Zhang X, Luo Y, Zou W, Zhang J, Fu J
Mediators of inflammation 2020;2020:7974537
Mediators of inflammation 2020;2020:7974537
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.
Elitt MS, Barbar L, Shick HE, Powers BE, Maeno-Hikichi Y, Madhavan M, Allan KC, Nawash BS, Gevorgyan AS, Hung S, Nevin ZS, Olsen HE, Hitomi M, Schlatzer DM, Zhao HT, Swayze A, LePage DF, Jiang W, Conlon RA, Rigo F, Tesar PJ
Nature 2020 Sep;585(7825):397-403
Nature 2020 Sep;585(7825):397-403
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.
Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333
Journal of neuroinflammation 2020 Nov 6;17(1):333
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Weinstock NI, Shin D, Dhimal N, Hong X, Irons EE, Silvestri NJ, Reed CB, Nguyen D, Sampson O, Cheng YC, Lau JTY, Bongarzone ER, Kofler J, Escolar ML, Gelb MH, Wrabetz L, Feltri ML
Neuron 2020 Jul 8;107(1):65-81.e9
Neuron 2020 Jul 8;107(1):65-81.e9
Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.
Matsumoto T, Chino H, Akiya M, Hashimura M, Yokoi A, Tochimoto M, Nakagawa M, Jiang Z, Saegusa M
Molecular carcinogenesis 2020 Dec;59(12):1409-1419
Molecular carcinogenesis 2020 Dec;59(12):1409-1419
Valproic Acid Enhances Reprogramming Efficiency and Neuronal Differentiation on Small Molecules Staged-Induction Neural Stem Cells: Suggested Role of mTOR Signaling.
Duan Q, Li S, Wen X, Sunnassee G, Chen J, Tan S, Guo Y
Frontiers in neuroscience 2019;13:867
Frontiers in neuroscience 2019;13:867
Myelin Damage in Diffuse Axonal Injury.
Mu J, Li M, Wang T, Li X, Bai M, Zhang G, Kong J
Frontiers in neuroscience 2019;13:217
Frontiers in neuroscience 2019;13:217
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Zhong J, Lan C, Zhang C, Yang Y, Chen WX, Zhang KY, Zhao HL, Fang XY, Li HH, Tan L, Wang P, Ge HF, Hu R, Feng H
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway.
Zhong J, Ge HF, Zhang C, Chen JY, Li HH, Fang XY, Tan L, Liu X, Jia ZC, Feng H, Hu R
Brain research 2019 Jul 1;1714:158-165
Brain research 2019 Jul 1;1714:158-165
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
Li HB
Heliyon 2019 Apr;5(4):e01567
Heliyon 2019 Apr;5(4):e01567
Distribution of endogenous normal tau in the mouse brain.
Kubo A, Misonou H, Matsuyama M, Nomori A, Wada-Kakuda S, Takashima A, Kawata M, Murayama S, Ihara Y, Miyasaka T
The Journal of comparative neurology 2019 Apr 1;527(5):985-998
The Journal of comparative neurology 2019 Apr 1;527(5):985-998
Examining the role of the surfactant family member SFTA3 in interneuron specification.
Chen CY, Anderson NC, Becker S, Schicht M, Stoddard C, Bräuer L, Paulsen F, Grabel L
PloS one 2018;13(11):e0198703
PloS one 2018;13(11):e0198703
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells.
Lager AM, Corradin OG, Cregg JM, Elitt MS, Shick HE, Clayton BLL, Allan KC, Olsen HE, Madhavan M, Tesar PJ
Nature communications 2018 Sep 13;9(1):3708
Nature communications 2018 Sep 13;9(1):3708
Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats.
Fan WL, Liu P, Wang G, Pu JG, Xue X, Zhao JH
Journal of cellular biochemistry 2018 Jun;119(6):4339-4351
Journal of cellular biochemistry 2018 Jun;119(6):4339-4351
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Xiao X, Feng YP, Du B, Sun HR, Ding YQ, Qi JG
BioTechniques 2017 Mar 1;62(3):115-122
BioTechniques 2017 Mar 1;62(3):115-122
Poly-L-ornithine enhances migration of neural stem/progenitor cells via promoting α-Actinin 4 binding to actin filaments.
Ge H, Yu A, Chen J, Yuan J, Yin Y, Duanmu W, Tan L, Yang Y, Lan C, Chen W, Feng H, Hu R
Scientific reports 2016 Nov 22;6:37681
Scientific reports 2016 Nov 22;6:37681
Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells.
Wang G, Zhang L, Chen X, Xue X, Guo Q, Liu M, Zhao J
Scientific reports 2016 May 13;6:25946
Scientific reports 2016 May 13;6:25946
Resetting cancer stem cell regulatory nodes upon MYC inhibition.
Galardi S, Savino M, Scagnoli F, Pellegatta S, Pisati F, Zambelli F, Illi B, Annibali D, Beji S, Orecchini E, Alberelli MA, Apicella C, Fontanella RA, Michienzi A, Finocchiaro G, Farace MG, Pavesi G, Ciafrè SA, Nasi S
EMBO reports 2016 Dec;17(12):1872-1889
EMBO reports 2016 Dec;17(12):1872-1889
Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway.
Ge H, Tan L, Wu P, Yin Y, Liu X, Meng H, Cui G, Wu N, Lin J, Hu R, Feng H
Scientific reports 2015 Oct 27;5:15535
Scientific reports 2015 Oct 27;5:15535
Neuropeptide Y has a protective role during murine retrovirus-induced neurological disease.
Du M, Butchi NB, Woods T, Morgan TW, Peterson KE
Journal of virology 2010 Nov;84(21):11076-88
Journal of virology 2010 Nov;84(21):11076-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 13999-1-AP(OLIG2 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using 13999-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13999-1-AP(OLIG2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13999-1-AP(OLIG2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
