HPA003256

antibody from Atlas Antibodies

Targeting: MEIS2 HsT18361, MRG1

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Chromatin Immunoprecipitation (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA003256

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003256, RRID:AB_1079356

Product name

Anti-MEIS2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MEIS2, Gene description: Meis homeobox 2, Alternative Gene Names: HsT18361, MRG1, Validated applications: IHC, ICC, ChIP, Uniprot ID: O14770, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.4 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation

De Wyn J, Zimmerman M, Weichert-Leahey N, Nunes C, Cheung B, Abraham B, Beckers A, Volders P, Decaesteker B, Carter D, Look A, De Preter K, Van Loocke W, Marshall G, Durbin A, Speleman F, Durinck K
Cancers 2021;13(19):4783

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Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

He B, Ebarasi L, Zhao Z, Guo J, Ojala J, Hultenby K, De Val S, Betsholtz C, Tryggvason K
Journal of the American Society of Nephrology 2014;25(12):2764-2777

Chromatin Immunoprecipitation

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

ChIP-Exo-Seq composite graph for Anti-MEIS2 (HPA003256, Lot A118643) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.