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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21542-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21542-1-AP, RRID:AB_10858481
- Product name
- GABPA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GABPA antibody (Cat. #21542-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
GABPA Expression in Endometrial Carcinoma: A Prognostic Marker.
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis.
GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.
Myeloid Zinc Finger 1 and GA Binding Protein Co-Operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells.
Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
Hu S, Feng J, Wang M, Wufuer R, Liu K, Zhang Z, Zhang Y
Redox biology 2022 Nov;57:102470
Redox biology 2022 Nov;57:102470
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
Fang Z, Zhang N, Yuan X, Xing X, Li X, Qin X, Liu Z, Neo S, Liu C, Kong F, Björkholm M, Fan Y, Xu D
Journal of experimental & clinical cancer research : CR 2022 May 12;41(1):173
Journal of experimental & clinical cancer research : CR 2022 May 12;41(1):173
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
Wang Y, Chen Y, Li C, Xiao Z, Yuan H, Zhang Y, Pang D, Tang X, Li M, Ouyang H
Biology 2022 Jan 14;11(1)
Biology 2022 Jan 14;11(1)
GABPA Expression in Endometrial Carcinoma: A Prognostic Marker.
Ma X, Lin Q, Cui G, Zhao J, Wei X, Li R, Mao H, Ma Y, Liu P, Pang Y
Disease markers 2021;2021:5552614
Disease markers 2021;2021:5552614
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H
Life science alliance 2020 Mar;3(3)
Life science alliance 2020 Mar;3(3)
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis.
Chen R, Zhu S, Fan XG, Wang H, Lotze MT, Zeh HJ 3rd, Billiar TR, Kang R, Tang D
Hepatology (Baltimore, Md.) 2018 May;67(5):1823-1841
Hepatology (Baltimore, Md.) 2018 May;67(5):1823-1841
GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.
Zhang S, Zhang K, Ji P, Zheng X, Jin J, Feng M, Liu P
BMC cancer 2017 May 26;17(1):380
BMC cancer 2017 May 26;17(1):380
Myeloid Zinc Finger 1 and GA Binding Protein Co-Operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells.
Verma NK, Gadi A, Maurizi G, Roy UB, Mansukhani A, Basilico C
Stem cells (Dayton, Ohio) 2017 Dec;35(12):2340-2350
Stem cells (Dayton, Ohio) 2017 Dec;35(12):2340-2350
Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.
Dworatzek E, Mahmoodzadeh S, Schubert C, Westphal C, Leber J, Kusch A, Kararigas G, Fliegner D, Moulin M, Ventura-Clapier R, Gustafsson JA, Davidson MM, Dragun D, Regitz-Zagrosek V
Cardiovascular research 2014 Jun 1;102(3):418-28
Cardiovascular research 2014 Jun 1;102(3):418-28
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, Li Y, Song S, Lin SC, Deng X, Camargo F, Avruch J, Chen L, Zhou D
Cell reports 2013 May 30;3(5):1663-77
Cell reports 2013 May 30;3(5):1663-77
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 21542-1-AP(GABPA antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21542-1-AP(GABPA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GABPA antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GABPA. This antibody recognizes human, mouse, rat antigen. The GABPA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
