Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 21542-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21542-1-AP, RRID:AB_10858481
- Product name
- GABPA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GABPA antibody (Cat. #21542-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DDX21 Links BRAF(V600E) and TERT to Promote Thyroid Cancer Progression.
Hypoxia-induced PRMT6 expression promotes temozolomide chemoresistance in glioblastoma via G3BP1.
Gabpα-Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat.
GABPα Promotes Lipid Deposition and Endoplasmic Reticulum Stress by Transcriptional-Regulated ATF4 in Porcine Skeletal Myofibers.
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1.
Taurine ameliorates deoxynivalenol-induced intestinal injury in piglets: Restoration of mitochondrial function linked to the PGC1α-NRF1/2 axis.
The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible.
The transcription factor GABPA is a master regulator of naive pluripotency.
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
The transcription factor GABPA is a master regulator of naïve pluripotency.
Unraveling the NRF2 confusion: Distinguishing nuclear respiratory factor 2 from nuclear erythroid factor 2.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
GABPA Expression in Endometrial Carcinoma: A Prognostic Marker.
The role of transcription factor Ap1 in the activation of the Nrf2/ARE pathway through TET1 in diabetic nephropathy.
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis.
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.
Myeloid Zinc Finger 1 and GA Binding Protein Co-Operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells.
Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Chen M, Jiang K, Zhang Q, Xiao X, Zhu L, Sang Y, Hu G, Yu S, Hong S, Lv W, Xiao H, Liu R
Thyroid : official journal of the American Thyroid Association 2026 Mar;36(3):305-319
Thyroid : official journal of the American Thyroid Association 2026 Mar;36(3):305-319
Hypoxia-induced PRMT6 expression promotes temozolomide chemoresistance in glioblastoma via G3BP1.
Chen S, Yu P, Sun Y, Yan Y, Zhang B, Li G
Journal of translational medicine 2026 Jan 2;24(1):226
Journal of translational medicine 2026 Jan 2;24(1):226
Gabpα-Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat.
Wang Z, Wang H, Kang Q, Pan R, He R, Yang M, Liu J, Peng X, Xie Y, Deng H, Wang W, Zhu Z, Ge J, Liu Y, Gao R, Guo Y, Yu P, Pan L, Li D, Maretich P, Luo X, Yu X, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e17426
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e17426
GABPα Promotes Lipid Deposition and Endoplasmic Reticulum Stress by Transcriptional-Regulated ATF4 in Porcine Skeletal Myofibers.
Huang B, Zhang Z, Shen J, Pang W
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6082-6096
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6082-6096
Gut microbiota regulation by Lactiplantibacillus plantarum SG5 enhances mitochondrial function in Parkinson's disease mice via the GLP-1/PGC-1α pathway.
Qi Y, Xie S, Chen J, Zhang C, Ma X, Yu Y, Yu X, Wang Y
The Journal of nutritional biochemistry 2025 Sep;143:109954
The Journal of nutritional biochemistry 2025 Sep;143:109954
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1.
Hong J, Sui P, Li Y, Xu KY, Lee JH, Wang J, Chen S, Zhang P, Wingate N, Noor A, Yuan Y, Hromas R, Zhou H, Hamamoto K, Su R, Yin CC, Ye F, Quesada AE, Chen J, Huang S, Zhou D, You MJ, Yang FC, Wang J, Xu M
Cell stem cell 2025 Mar 6;32(3):463-478.e6
Cell stem cell 2025 Mar 6;32(3):463-478.e6
Taurine ameliorates deoxynivalenol-induced intestinal injury in piglets: Restoration of mitochondrial function linked to the PGC1α-NRF1/2 axis.
Ji X, Ding H, Zhou F, Zhang F, Wu D
Ecotoxicology and environmental safety 2025 Mar 1;292:117938
Ecotoxicology and environmental safety 2025 Mar 1;292:117938
The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible.
Stevers NO, Kim S, Yuan JB, Barger CJ, Hong C, Lenzo O, McKinney AM, Wu SH, Lee YJ, Kwok DW, Suwala AK, Appin CL, Gordan JD, Molinaro AM, Song JS, Costello JF
Molecular cell 2025 Jun 19;85(12):2337-2354.e9
Molecular cell 2025 Jun 19;85(12):2337-2354.e9
The transcription factor GABPA is a master regulator of naive pluripotency.
Zhou C, Wang M, Zhang C, Zhang Y
Nature cell biology 2025 Jan;27(1):48-58
Nature cell biology 2025 Jan;27(1):48-58
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Du L, Liu S, Lu Y, Ren D, Yu X, Hu Y, Yang T, Yang Q, Ming J, Zhang J, Yin X, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
The transcription factor GABPA is a master regulator of naïve pluripotency.
Zhou C, Wang M, Zhang C, Zhang Y
bioRxiv : the preprint server for biology 2024 Nov 21;
bioRxiv : the preprint server for biology 2024 Nov 21;
Unraveling the NRF2 confusion: Distinguishing nuclear respiratory factor 2 from nuclear erythroid factor 2.
George M, Reddy AP, Reddy PH, Kshirsagar S
Ageing research reviews 2024 Jul;98:102353
Ageing research reviews 2024 Jul;98:102353
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks.
Hu S, Feng J, Wang M, Wufuer R, Liu K, Zhang Z, Zhang Y
Redox biology 2022 Nov;57:102470
Redox biology 2022 Nov;57:102470
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
Fang Z, Zhang N, Yuan X, Xing X, Li X, Qin X, Liu Z, Neo S, Liu C, Kong F, Björkholm M, Fan Y, Xu D
Journal of experimental & clinical cancer research : CR 2022 May 12;41(1):173
Journal of experimental & clinical cancer research : CR 2022 May 12;41(1):173
TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis.
Wang Y, Chen Y, Li C, Xiao Z, Yuan H, Zhang Y, Pang D, Tang X, Li M, Ouyang H
Biology 2022 Jan 14;11(1)
Biology 2022 Jan 14;11(1)
GABPA Expression in Endometrial Carcinoma: A Prognostic Marker.
Ma X, Lin Q, Cui G, Zhao J, Wei X, Li R, Mao H, Ma Y, Liu P, Pang Y
Disease markers 2021;2021:5552614
Disease markers 2021;2021:5552614
The role of transcription factor Ap1 in the activation of the Nrf2/ARE pathway through TET1 in diabetic nephropathy.
Tan Y, Cao H, Li Q, Sun J
Cell biology international 2021 Aug;45(8):1654-1665
Cell biology international 2021 Aug;45(8):1654-1665
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H
Life science alliance 2020 Mar;3(3)
Life science alliance 2020 Mar;3(3)
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis.
Chen R, Zhu S, Fan XG, Wang H, Lotze MT, Zeh HJ 3rd, Billiar TR, Kang R, Tang D
Hepatology (Baltimore, Md.) 2018 May;67(5):1823-1841
Hepatology (Baltimore, Md.) 2018 May;67(5):1823-1841
Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson's Disease.
Wang Y, Zhao W, Li G, Chen J, Guan X, Chen X, Guan Z
PPAR research 2017;2017:4089214
PPAR research 2017;2017:4089214
GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.
Zhang S, Zhang K, Ji P, Zheng X, Jin J, Feng M, Liu P
BMC cancer 2017 May 26;17(1):380
BMC cancer 2017 May 26;17(1):380
Myeloid Zinc Finger 1 and GA Binding Protein Co-Operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells.
Verma NK, Gadi A, Maurizi G, Roy UB, Mansukhani A, Basilico C
Stem cells (Dayton, Ohio) 2017 Dec;35(12):2340-2350
Stem cells (Dayton, Ohio) 2017 Dec;35(12):2340-2350
Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.
Dworatzek E, Mahmoodzadeh S, Schubert C, Westphal C, Leber J, Kusch A, Kararigas G, Fliegner D, Moulin M, Ventura-Clapier R, Gustafsson JA, Davidson MM, Dragun D, Regitz-Zagrosek V
Cardiovascular research 2014 Jun 1;102(3):418-28
Cardiovascular research 2014 Jun 1;102(3):418-28
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, Li Y, Song S, Lin SC, Deng X, Camargo F, Avruch J, Chen L, Zhou D
Cell reports 2013 May 30;3(5):1663-77
Cell reports 2013 May 30;3(5):1663-77
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 21542-1-AP(GABPA antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21542-1-AP(GABPA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GABPA antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GABPA. This antibody recognizes human, mouse, rat antigen. The GABPA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
