Antibody data
- Antibody Data
- Antigen structure
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- Product number
- MA-1H10 - Provider product page
- Provider
- Molecular Innovations
- Product name
- Anti-VLDLR
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Description
- Inhibitory Anti Human VLDL receptor, clone 1H10. Monoclonal antibody produced in mouse. Useful for ELISA and western blot under non-reducing conditions. Binds to an epitope on the C-terminus of VLDL receptor ligand binding domain (amino acids 191-355, UniProtKB: locus VLDLR_HUMAN, accession P98155) and blocks apoE4 binding. Purified by immobilized Protein A. IgG1 class. References: Functional domains of the very low density lipoprotein receptor: molecular analysis of ligand binding and acid-dependent ligand dissociation mechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 (1999). The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 (2005).
- Reactivity
- Human
- Host
- Mouse
- Epitope
- C-terminus of VLDL receptor ligand binding domain (191-355)
- Isotype
- IgG
- Antibody clone number
- 1H10
- Vial size
- 500 µl
- Concentration
- 2 mg/ml
- Storage
- -70 C
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