12081-1-AP

antibody from Proteintech Group

Targeting: NEUROD1 BETA2, BHF-1, bHLHa3, MODY6, NEUROD

Provider product page for 12081-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 12081-1-AP - Provider product page
Provider: Proteintech Group
Product name: NEUROD1 antibody
Antibody type: Polyclonal
Description: NEUROD1 antibody (Cat. #12081-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

NEUROD1 protein structure - 12081-1-AP shown in red.

Submitted references A sulfated manno-glucuronan ameliorates β-cell dysfunction in type 2 diabetes by targeting ALDH1A3.

Zhang W, Zhang F, Zou X, Wu N, He S, Lu L, Xu C, Xu W, Jin W, Zhou J
Carbohydrate polymers 2026 Jun 15;382:125227

H3K18la-driven methyltransferase 1-mediated upregulation of NeuroD1 m7G modification in promoting ferroptosis resistance in rheumatoid arthritis synovial fibroblasts.

Xu Y, Liu W, Zai Z, Qian X, Hu W, Peng X, Chen F
International journal of biological macromolecules 2026 Jan;335(Pt 1):149196

Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper function.

Yin W, Yao H, Li X, Pan W, Zhang Y, Wang C, Deng L, Lin C, Zhang ZM, Pan J, Han S, Tang Z, Zhao Z, Zhu C, Li S, Huang M, Chen M, Xue Y, Zhang J, Ye W, Zhang D
Cell reports. Medicine 2026 Jan 20;7(1):102569

ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.

Xiao J, Liu Y, Peng M, Ma J, Lei S, Chen Y, Liu S, Zhao X, Lu D, Sun Q
Alzheimer's research & therapy 2026 Feb 5;18(1)

Neurogenic inducers inhibit the proliferation of pancreatic cancer by promoting tumor cell transdifferentiation.

Guo D, Shi S, Ye L, Yang M, Peng W, Yang J, Xu J, Fei Q, Li H, Jin K, Hu X, Wu W
Journal of experimental & clinical cancer research : CR 2025 Nov 12;44(1):304

Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.

Shen J, Gao L, Gao J, Wang L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J
Biomolecules 2025 Jul 27;15(8)

A developmental atlas of mouse vestibular-like inner ear organoids.

Matern MS, Heller S
iScience 2025 Feb 21;28(2):111817

Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus.

Tao L, Teng L, Ge M, Wang Y, Hu C, Chen J, Zhao J, Cheng L, Zhang Z, Qin W, Jia Y, Mi D, Yuan Z, Chen L
Nature communications 2025 Dec 15;16(1):11117

Extracellular lactate improves neurogenesis by modulating H3K9 lactylation and SnoN expression under hypoxic conditions.

Xu W, Zhao A, Han R, Wei J, Yu Q, Wang M, Li H, Xu B, Li M, Chi G
Stem cell research & therapy 2025 Aug 27;16(1):462

Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells.

Tang W, He D, Li X, Feng Y, Xu Y, Hu J, Xu W, Xue L
Scientific reports 2025 Aug 11;15(1):29291

POU2F3-positive small cell carcinoma of the bladder: A clinicopathologic analysis of 4 cases and literature review.

Cai Z, Cheng X, Liao S, Zou W, Li L, Liu F, Huang W
Pathology, research and practice 2024 May;257:155296

Discovery of a Long Half-Life AURKA Inhibitor to Treat MYC-Amplified Solid Tumors as a Monotherapy and in Combination with Everolimus.

Chang CP, Yeh TK, Chen CT, Wang WP, Chen YT, Tsai CH, Chen YF, Ke YY, Wang JY, Chen CP, Hsieh TC, Wu MH, Huang CL, Chen YP, Zhuang H, Chi YH
Molecular cancer therapeutics 2024 Jun 4;23(6):766-779

The molecular subtypes of small cell lung cancer defined by key transcription factors and their clinical significance.

Yu Z, Zou J, Xu F
Lung cancer (Amsterdam, Netherlands) 2024 Dec;198:108033

Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.

Lin HH, Yu IS, Cheng MS, Chang TJ, Lin HY, Chang YC, Ko CJ, Chen PH, Lin SW, Huang TC, Huang SY, Chen TY, Kan KW, Huang HP, Lee MS
Nature communications 2024 Dec 3;15(1):10537

NEUROD1 predicts better prognosis in pancreatic cancer revealed by a TILs-based prognostic signature.

Jiang Z, Pan J, Lu J, Mei J, Xu R, Xia D, Yang X, Wang H, Liu C, Xu J, Ding J
Frontiers in pharmacology 2022;13:1025921

Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.

Welch GM, Boix CA, Schmauch E, Davila-Velderrain J, Victor MB, Dileep V, Bozzelli PL, Su Q, Cheng JD, Lee A, Leary NS, Pfenning AR, Kellis M, Tsai LH
Science advances 2022 Sep 30;8(39):eabo4662

Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.

Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J
Human molecular genetics 2022 Oct 10;31(20):3504-3520

Three-dimensional cell-culture platform based on hydrogel with tunable microenvironmental properties to improve insulin-secreting function of MIN6 cells.

Zhang M, Yan S, Xu X, Yu T, Guo Z, Ma M, Zhang Y, Gu Z, Feng Y, Du C, Wan M, Hu K, Han X, Gu N
Biomaterials 2021 Mar;270:120687

Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer.

Patel AS, Yoo S, Kong R, Sato T, Sinha A, Karam S, Bao L, Fridrikh M, Emoto K, Nudelman G, Powell CA, Beasley MB, Zhu J, Watanabe H
Science advances 2021 Jan;7(5)

Exploration of gastric neuroendocrine carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro analysis.

Xie J, Chen P, Xie H, Sun Y, Huang Z, Wei R, Miao Z, Wang Q, Zhang SD, Wong KH, Lin Y, Huang C, Kwok HF
Computational and structural biotechnology journal 2020;18:2610-2620

Centrioles are amplified in cycling progenitors of olfactory sensory neurons.

Ching K, Stearns T
PLoS biology 2020 Sep;18(9):e3000852

CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.

Sood S, Weber CM, Hodges HC, Krokhotin A, Shalizi A, Crabtree GR
Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 8;117(36):22331-22340

Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells.

Zhu K, Qian L, Lin Y, An L, Mu G, Ma G, Ren L
Journal of diabetes research 2019;2019:5245063

EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways.

Yang L, Zhu Y, Kong D, Gong J, Yu W, Liang Y, Nie Y, Teng CB
International journal of biological sciences 2019;15(12):2561-2575

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer.

Böttger F, Semenova EA, Song JY, Ferone G, van der Vliet J, Cozijnsen M, Bhaskaran R, Bombardelli L, Piersma SR, Pham TV, Jimenez CR, Berns A
Cell reports 2019 Jun 11;27(11):3345-3358.e4

Exposure to 1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells.

Chen C, Ma Q, Liu C, Deng P, Zhu G, Zhang L, He M, Lu Y, Duan W, Pei L, Li M, Yu Z, Zhou Z
Scientific reports 2014 May 29;4:5103

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Y79 cells were subjected to SDS PAGE followed by western blot with 12081-1-AP(NEUROD1 antibody) at dilution of 1:200
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The NEUROD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NEUROD1. This antibody recognizes human,mouse,rat antigen. The NEUROD1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Appendix: 12081-1-AP.pdf

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