Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2841945 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 489-518), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 489-518, C-Term
- Antibody clone number
- RB3319
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.
Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis.
Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation.
Toll-like receptor 3 signaling attenuates liver regeneration.
RIP3, a novel apoptosis-inducing kinase.
Deutsch M, Graffeo CS, Rokosh R, Pansari M, Ochi A, Levie EM, Van Heerden E, Tippens DM, Greco S, Barilla R, Tomkötter L, Zambirinis CP, Avanzi N, Gulati R, Pachter HL, Torres-Hernandez A, Eisenthal A, Daley D, Miller G
Cell death & disease 2015 May 7;6:e1759
Cell death & disease 2015 May 7;6:e1759
Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis.
Dara L, Johnson H, Suda J, Win S, Gaarde W, Han D, Kaplowitz N
Hepatology (Baltimore, Md.) 2015 Dec;62(6):1847-57
Hepatology (Baltimore, Md.) 2015 Dec;62(6):1847-57
Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation.
Roychowdhury S, Chiang DJ, Mandal P, McMullen MR, Liu X, Cohen JI, Pollard J, Feldstein AE, Nagy LE
Alcoholism, clinical and experimental research 2012 Jul;36(7):1139-47
Alcoholism, clinical and experimental research 2012 Jul;36(7):1139-47
Toll-like receptor 3 signaling attenuates liver regeneration.
Zorde-Khvalevsky E, Abramovitch R, Barash H, Spivak-Pohis I, Rivkin L, Rachmilewitz J, Galun E, Giladi H
Hepatology (Baltimore, Md.) 2009 Jul;50(1):198-206
Hepatology (Baltimore, Md.) 2009 Jul;50(1):198-206
RIP3, a novel apoptosis-inducing kinase.
Sun X, Lee J, Navas T, Baldwin DT, Stewart TA, Dixit VM
The Journal of biological chemistry 1999 Jun 11;274(24):16871-5
The Journal of biological chemistry 1999 Jun 11;274(24):16871-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC