Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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Validation data
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- Product number
- H00054101-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00054101-M01, RRID:AB_536802
- Product name
- Mouse Monoclonal RIPK4 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. RIPK4 - receptor-interacting serine-threonine kinase 4
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization.
RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation.
Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair.
Tanghe G, Urwyler-Rösselet C, De Groote P, Dejardin E, De Bock PJ, Gevaert K, Vandenabeele P, Declercq W
Cellular and molecular life sciences : CMLS 2018 Aug;75(15):2827-2841
Cellular and molecular life sciences : CMLS 2018 Aug;75(15):2827-2841
RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation.
Kopparam J, Chiffelle J, Angelino P, Piersigilli A, Zangger N, Delorenzi M, Meylan E
Cell death and differentiation 2017 Oct;24(10):1761-1771
Cell death and differentiation 2017 Oct;24(10):1761-1771
Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
Lee P, Jiang S, Li Y, Yue J, Gou X, Chen SY, Zhao Y, Schober M, Tan M, Wu X
The EMBO journal 2017 Jul 3;36(13):1963-1980
The EMBO journal 2017 Jul 3;36(13):1963-1980
RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair.
Adams S, Munz B
Experimental cell research 2010 Jan 1;316(1):126-37
Experimental cell research 2010 Jan 1;316(1):126-37
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: RIPK4 Antibody (2G3) [H00054101-M01] - RIPK4 monoclonal antibody (M01), clone 2G3 Analysis of RIPK4 expression in A-431.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: RIPK4 Antibody (2G3) [H00054101-M01] - Detection limit for recombinant GST tagged RIPK4 is approximately 0.3ng/ml as a capture antibody.