Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB362A - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal ChemR23/CMKLR1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human ChemR23. Stains human ChemR23-transfected cells but not irrelevant transfectants.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells.
ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
Vinci P, Bastone A, Schiarea S, Cappuzzello C, Del Prete A, Dander E, Biondi A, D'Amico G
Cytotherapy 2017 Feb;19(2):200-210
Cytotherapy 2017 Feb;19(2):200-210
ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
Herová M, Schmid M, Gemperle C, Hersberger M
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2330-7
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 1;194(5):2330-7
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Detection of ChemR23 in Human Whole Blood Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human IL-3 R alpha/CD123 PE-conjugated Monoclonal Antibody (Catalog # FAB301P) and either (A) Mouse Anti-Human ChemR23 APC-conjugated Monoclonal Antibody (Catalog # FAB362A) or (B) Mouse IgG3 Allophycocyanin Isotype Control (Catalog # IC007A). View our protocol for Staining Membrane-associated Proteins.