Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B8889 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-PACS2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- PACS2 (phosphofurin acidic cluster sorting protein 2) is a protein-coding gene. Diseases associated with PACS2 include kaposi's sarcoma, and sarcoma. An important paralog of this gene is PACS1. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In additon, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Storage
- Store at -20°C. Aliquoting is unnecessary for -20°C storage.
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