Tissue expression
Cell line expression
Protein structure
TBL1XR1
TBL1X receptor 1C21, DC42, FLJ12894, IRA1, TBLR1
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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Novus Biologicals | H00079718-M01 | 1 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
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antibodies-online | ABIN4948267 | 5 references | Monoclonal |
WB
EL
ICC
IHC |
|
Abnova Corporation | H00079718-M01 | 1 references | Monoclonal |
WB
EL
ICC
IHC |
|
LSBio | LS-C133815 | Monoclonal |
WB
EL
ICC
IHC |
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Atlas Antibodies | HPA019182 | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider