60345-1-Ig

antibody from Proteintech Group

Targeting: NR1H2 LXR-b, LXRb, NER, NER-I, RIP15, UNR

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

60345-1-Ig

Provider

Proteintech Group

Product name

NR1H2 antibody

Antibody type

Monoclonal

Description

KD/KO validated NR1H2 antibody (Cat. #60345-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1E12B10

Vial size

20ul, 150ul

References

Submitted references

Protective effect of liver X receptor on cigarette smoke and lipopolysaccharide induced airway inflammation and emphysema in mice.

Yu F, Gao L, Xu K, Yang X, Zhang J, Tang Y, Ma Z, Gu W, Wu B, Shi Y
Experimental lung research 2024;50(1):53-64

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Liver X receptor agonists exert antitumor effects against hepatocellular carcinoma via inducing REPS2 expression.

He XY, Zhu MM, Zheng J, Wang CY, Zhao XK, Zhang BT, Zhou DC, Zhang S, Yang XX, Duan YJ, Han JH, Chen YL
Acta pharmacologica Sinica 2023 Mar;44(3):635-646

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Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407.

Han W, Zhang D, Zhang P, Tao Q, Du X, Yu C, Dong P, Zhu Y
BMC complementary medicine and therapies 2023 Dec 8;23(1):445

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Polysaccharide MCP extracted from Morchella esculenta reduces atherosclerosis in LDLR-deficient mice.

Wang D, Yin Z, Ma L, Han L, Chen Y, Pan W, Gong K, Gao Y, Yang X, Chen Y, Han J, Duan Y
Food & function 2021 Jun 7;12(11):4842-4854

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Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.

Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667

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EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.

Chen T, Xu J, Fu W
Frontiers in oncology 2020;10:1688

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TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.

Zhao D, Li J, Xue C, Feng K, Liu L, Zeng P, Wang X, Chen Y, Li L, Zhang Z, Duan Y, Han J, Yang X
The Journal of biological chemistry 2020 Nov 27;295(48):16314-16327

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Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.

Wang X, Zhao H, Yan W, Liu Y, Yin T, Wang S, Fan M, Li C, Zhang L, Tao L
Biochemical and biophysical research communications 2019 Sep 3;516(4):1103-1109

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Upregulation of 24(R/S),25-epoxycholesterol and 27-hydroxycholesterol suppresses the proliferation and migration of gastric cancer cells.

Guo F, Hong W, Yang M, Xu D, Bai Q, Li X, Chen Z
Biochemical and biophysical research communications 2018 Oct 12;504(4):892-898

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Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.

Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, Zhang X, Yang S, Sun L, Yu M, Yang J, Li X, Hu W, Miao RQ, Zhu Y, Li L, Han J, Chen Y, Duan Y
British journal of pharmacology 2018 May;175(9):1486-1503

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25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.

Liu Y, Wei Z, Ma X, Yang X, Chen Y, Sun L, Ma C, Miao QR, Hajjar DP, Han J, Duan Y
Journal of lipid research 2018 Mar;59(3):439-451

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Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol.

Liu Y, Wei Z, Zhang Y, Ma X, Chen Y, Yu M, Ma C, Li X, Cao Y, Liu J, Han J, Yang X, Duan Y
Journal of lipid research 2018 Dec;59(12):2287-2296