Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15767-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15767-1-AP, RRID:AB_2236213
- Product name
- NQO2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NQO2 antibody (Cat. #15767-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The specific NQO2 inhibitor, S29434, only marginally improves the survival of dopamine neurons in MPTP-intoxicated mice.
Proteomic and Phosphoproteomic Analysis of Right Ventricular Hypertrophy in the Pulmonary Hypertension Rat Model.
Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity.
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Autophagy and neuroprotection in astrocytes exposed to 6-hydroxydopamine is negatively regulated by NQO2: relevance to Parkinson's disease.
Realgar-induced nephrotoxicity via ferroptosis in mice.
Apigenin and Luteolin Regulate Autophagy by Targeting NRH-Quinone Oxidoreductase 2 in Liver Cells.
PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: a potential new therapeutic perspective for an old drug.
Downregulation of quinone reductase 2 attenuates vascular smooth muscle cells proliferation and neointimal formation in balloon injured rat carotid artery.
Vallucci M, Boutin JA, Janda E, Blandel F, Musgrove R, Di Monte D, Ferry G, Michel PP, Hirsch EC
Journal of neural transmission (Vienna, Austria : 1996) 2024 Jan;131(1):1-11
Journal of neural transmission (Vienna, Austria : 1996) 2024 Jan;131(1):1-11
Proteomic and Phosphoproteomic Analysis of Right Ventricular Hypertrophy in the Pulmonary Hypertension Rat Model.
Luo A, Jia Y, Hao R, Zhou X, Bao C, Yang L, Gu C, Tang H, Chu AA
Journal of proteome research 2024 Jan 5;23(1):264-276
Journal of proteome research 2024 Jan 5;23(1):264-276
Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity.
Meng Y, Iyamu ID, Ahmed NAM, Huang R
ACS chemical biology 2024 Jan 19;19(1):89-100
ACS chemical biology 2024 Jan 19;19(1):89-100
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Wang TX, Duan KL, Huang ZX, Xue ZA, Liang JY, Dang Y, Zhang A, Xiong Y, Ding C, Guan KL, Yuan HX
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Autophagy and neuroprotection in astrocytes exposed to 6-hydroxydopamine is negatively regulated by NQO2: relevance to Parkinson's disease.
Janda E, Parafati M, Martino C, Crupi F, George William JN, Reybier K, Arbitrio M, Mollace V, Boutin JA
Scientific reports 2023 Dec 7;13(1):21624
Scientific reports 2023 Dec 7;13(1):21624
Realgar-induced nephrotoxicity via ferroptosis in mice.
Zhang S, Cao S, Zhou H, Li L, Hu Q, Mao X, Ji S
Journal of applied toxicology : JAT 2022 Nov;42(11):1843-1853
Journal of applied toxicology : JAT 2022 Nov;42(11):1843-1853
Apigenin and Luteolin Regulate Autophagy by Targeting NRH-Quinone Oxidoreductase 2 in Liver Cells.
Janda E, Martino C, Riillo C, Parafati M, Lascala A, Mollace V, Boutin JA
Antioxidants (Basel, Switzerland) 2021 May 13;10(5)
Antioxidants (Basel, Switzerland) 2021 May 13;10(5)
PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: a potential new therapeutic perspective for an old drug.
He T, Hatem E, Vernis L, Lei M, Huang ME
Journal of experimental & clinical cancer research : CR 2015 Dec 21;34:152
Journal of experimental & clinical cancer research : CR 2015 Dec 21;34:152
Downregulation of quinone reductase 2 attenuates vascular smooth muscle cells proliferation and neointimal formation in balloon injured rat carotid artery.
Zhang XW, Wang Y, Cai JB, Hou XF, Wang HG, Zou JG, Cao KJ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;29(3-4):453-62
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;29(3-4):453-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15767-1-AP(NQO2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using NQO2 antibody 15767-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15767-1-AP(NQO2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15767-1-AP(NQO2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue