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- References [20]
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- Product number
- 25315-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- RUNX1 (middle) antibody
- Antibody type
- Polyclonal
- Description
- RUNX1 (middle) antibody (Cat. #25315-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.
RUNX1 promotes angiogenesis in colorectal cancer by regulating the crosstalk between tumor cells and tumor associated macrophages.
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia.
RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway.
Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner.
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress.
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis.
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells.
ASCL1 represses a SOX9(+) neural crest stem-like state in small cell lung cancer.
Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia.
Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.
CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a.
RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia.
The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation.
Li Y, Lai J, Ran M, Yi T, Zhou L, Luo J, Liu X, Tang X, Huang M, Xie X, Li H, Yang Y, Zou W, Wu J
European journal of pharmacology 2024 May 15;971:176548
European journal of pharmacology 2024 May 15;971:176548
RUNX1 promotes angiogenesis in colorectal cancer by regulating the crosstalk between tumor cells and tumor associated macrophages.
Guo X, Zhang H, He C, Qin K, Lai Q, Fang Y, Chen Q, Li W, Wang Y, Wang X, Li A, Liu S, Li Q
Biomarker research 2024 Feb 28;12(1):29
Biomarker research 2024 Feb 28;12(1):29
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Li Q, Xiao C, Gu J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2024 Feb 15;128:111459
International immunopharmacology 2024 Feb 15;128:111459
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia.
Zhou L, Ni C, Liao R, Tang X, Yi T, Ran M, Huang M, Liao R, Zhou X, Qin D, Wang L, Huang F, Xie X, Wan Y, Luo J, Wang Y, Wu J
eLife 2024 Apr 4;13
eLife 2024 Apr 4;13
RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway.
Zhu Q, Zhang X, Lu F, Miao S, Zhang C, Liu Z, Gao Z, Qi M, An X, Geng P, Wang S, Ren H, Han F, Zhang R, Zha D
Cell communication and signaling : CCS 2024 Apr 12;22(1):227
Cell communication and signaling : CCS 2024 Apr 12;22(1):227
Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner.
Long F, Li L, Xie C, Ma M, Wu Z, Lu Z, Liu B, Yang M, Zhang F, Ning Z, Zhong C, Yu B, Liu S, Wan L, Tian B, Yang K, Guo Y, Chen M, Chou J, Li X, Hu G, Lin C, Zhang Y
International journal of biological sciences 2023;19(12):3781-3803
International journal of biological sciences 2023;19(12):3781-3803
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
Zheng M, Li H, Gao Y, Brigstock DR, Gao R
European journal of pharmacology 2023 Oct 15;957:176000
European journal of pharmacology 2023 Oct 15;957:176000
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress.
Jiang X, Ma Y, Wang T, Zhou H, Wang K, Shi W, Qin L, Guan J, Li L, Long B, Wang J, Guan X, Ye H, Yang J, Yu Z, Jiao Z
Gastroenterology 2023 Jun;164(7):1232-1247
Gastroenterology 2023 Jun;164(7):1232-1247
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Xiao C, Li Q, Xiao J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2023 Jul;120:110318
International immunopharmacology 2023 Jul;120:110318
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice.
Li M, Gan C, Zhang R, Wang J, Wang Y, Zhu W, Liu L, Shang J, Zhao Q
Immunology 2023 Dec;170(4):495-509
Immunology 2023 Dec;170(4):495-509
Targeting TLR2/Rac1/cdc42/JNK Pathway to Reveal That Ruxolitinib Promotes Thrombocytopoiesis.
Yang S, Tang X, Wang L, Ni C, Wu Y, Zhou L, Zeng Y, Zhao C, Wu A, Wang Q, Xu X, Wang Y, Chen R, Zhang X, Zou L, Huang X, Wu J
International journal of molecular sciences 2022 Dec 17;23(24)
International journal of molecular sciences 2022 Dec 17;23(24)
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Dubey S, Dubey PK, Umeshappa CS, Ghebre YT, Krishnamurthy P
Journal of cellular physiology 2022 Apr;237(4):2169-2182
Journal of cellular physiology 2022 Apr;237(4):2169-2182
Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells.
Samara VA, Das S, Reddy MA, Tanwar VS, Stapleton K, Leung A, Abdollahi M, Ganguly R, Lanting L, Natarajan R
Cells 2021 Oct 9;10(10)
Cells 2021 Oct 9;10(10)
ASCL1 represses a SOX9(+) neural crest stem-like state in small cell lung cancer.
Olsen RR, Ireland AS, Kastner DW, Groves SM, Spainhower KB, Pozo K, Kelenis DP, Whitney CP, Guthrie MR, Wait SJ, Soltero D, Witt BL, Quaranta V, Johnson JE, Oliver TG
Genes & development 2021 Jun;35(11-12):847-869
Genes & development 2021 Jun;35(11-12):847-869
Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia.
Qing Y, Wang X, Wang H, Hu P, Li H, Yu X, Zhu M, Wang Z, Zhu Y, Xu J, Guo Q, Hui H
Cell communication and signaling : CCS 2021 Aug 9;19(1):83
Cell communication and signaling : CCS 2021 Aug 9;19(1):83
Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.
Zhang L, Wang W, Zhang S, Wang Y, Guo W, Liu Y, Wang Y, Zhang Y
Cancer cell international 2020;20:182
Cancer cell international 2020;20:182
CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a.
Gan X, Zhu H, Jiang X, Obiegbusi SC, Yong M, Long X, Hu J
Molecular cancer 2020 Feb 28;19(1):45
Molecular cancer 2020 Feb 28;19(1):45
RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia.
Bera R, Chiu MC, Huang YJ, Lin TH, Kuo MC, Shih LY
Journal of hematology & oncology 2019 Oct 22;12(1):104
Journal of hematology & oncology 2019 Oct 22;12(1):104
The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation.
Wang D, Diao H, Getzler AJ, Rogal W, Frederick MA, Milner J, Yu B, Crotty S, Goldrath AW, Pipkin ME
Immunity 2018 Apr 17;48(4):659-674.e6
Immunity 2018 Apr 17;48(4):659-674.e6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RUNX1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RUNX1. This antibody recognizes human, mouse antigen. The RUNX1 antibody has been validated for the following applications: ELISA, WB analysis.
